NL8004836A - Aroylethenylpiperidinobutyrofenonen met anti-psycho- tische werking. - Google Patents

Aroylethenylpiperidinobutyrofenonen met anti-psycho- tische werking. Download PDF

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Publication number
NL8004836A
NL8004836A NL8004836A NL8004836A NL8004836A NL 8004836 A NL8004836 A NL 8004836A NL 8004836 A NL8004836 A NL 8004836A NL 8004836 A NL8004836 A NL 8004836A NL 8004836 A NL8004836 A NL 8004836A
Authority
NL
Netherlands
Prior art keywords
compound according
pharmaceutically acceptable
acid addition
acceptable acid
addition salt
Prior art date
Application number
NL8004836A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of NL8004836A publication Critical patent/NL8004836A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL8004836A 1979-09-04 1980-08-27 Aroylethenylpiperidinobutyrofenonen met anti-psycho- tische werking. NL8004836A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7249979 1979-09-04
US06/072,499 US4283404A (en) 1979-09-04 1979-09-04 Aroylethenylpiperidinobutyrophenone antipsychotic agents

Publications (1)

Publication Number Publication Date
NL8004836A true NL8004836A (nl) 1981-03-06

Family

ID=22107983

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8004836A NL8004836A (nl) 1979-09-04 1980-08-27 Aroylethenylpiperidinobutyrofenonen met anti-psycho- tische werking.

Country Status (14)

Country Link
US (1) US4283404A (https=)
JP (1) JPS5640666A (https=)
AU (1) AU538603B2 (https=)
BE (1) BE885018A (https=)
CA (1) CA1147735A (https=)
CH (1) CH646951A5 (https=)
DE (1) DE3031929A1 (https=)
ES (1) ES494223A0 (https=)
FR (1) FR2464252A1 (https=)
GB (3) GB2057444B (https=)
IL (1) IL60743A (https=)
IT (1) IT1145386B (https=)
NL (1) NL8004836A (https=)
ZA (1) ZA804664B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0661266A1 (en) * 1993-12-27 1995-07-05 Toa Eiyo Ltd. Substituted cyclic amine compounds as 5HT2 antagonists
WO2007136790A2 (en) 2006-05-18 2007-11-29 Mannkind Corporation Intracellular kinase inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives
GB979555A (en) * 1962-01-17 1965-01-06 Bellon Labor Sa Roger New benzyl piperidyl ketones
US3689492A (en) * 1965-09-10 1972-09-05 Hans Detlef Schroeder 1-{8 4{40 -OXO-4-(p-FLUOROPHENYL)-n-BUTYL-1{40 {9 -4-ACETYL-4-(m-HYDROXY-PHENYL-PIPERIDINE
US3646014A (en) * 1966-05-09 1972-02-29 Aldrich Chem Co Inc Chemical compounds
US3484446A (en) * 1967-01-16 1969-12-16 Aldrich Chem Co Inc 1-(3-(4-fluorobenzoyl)propyl) - and 1 - (1,1-ethylenedioxy - 1 - (4 - fluorophenyl)-4-butyl)-4-piperidyl carbamates
NL130760C (https=) * 1967-01-25
CH532048A (de) * 1967-12-01 1973-02-15 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Zimtsäureamiden
CH516557A (de) * 1967-12-01 1971-12-15 Thomae Gmbh Dr K Verfahren zur Herstellung neuer Zimtsäureamide
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
US3637712A (en) * 1970-01-26 1972-01-25 Bristol Myers Co Piperidylpropanol compounds
US3852455A (en) * 1970-11-27 1974-12-03 Richardson Merrell Inc 4-{8 4({60 hydroxybenzyl)piperidino{9 -4-fluorobutyrophenone derivatives as tranquilizers
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives
US3816443A (en) * 1972-02-17 1974-06-11 Merck & Co Inc 4-(benzothiazol-2-yl)fluoro phenyl-acetic acids
US3797932A (en) * 1972-10-31 1974-03-19 Eastman Kodak Co Vibration isolation arrangement for aperture card photographic copying machine
US4101662A (en) * 1973-05-03 1978-07-18 A. H. Robins Company, Incorporated Method for inhibiting emesis and compositions therefor
SE7409245L (https=) * 1973-07-19 1975-01-20 Robins Co Inc A H
GB1535791A (en) * 1975-05-07 1978-12-13 Ferrosan Ab Derivatives of 4-piperidinol
CH602642A5 (https=) * 1975-11-14 1978-07-31 Orgamol Sa

Also Published As

Publication number Publication date
ES8106144A1 (es) 1981-08-01
JPS6341389B2 (https=) 1988-08-17
CH646951A5 (de) 1984-12-28
GB8302742D0 (en) 1983-03-02
ZA804664B (en) 1981-07-29
AU6148980A (en) 1981-03-12
GB8303500D0 (en) 1983-03-16
GB2121032B (en) 1984-06-06
AU538603B2 (en) 1984-08-23
FR2464252A1 (fr) 1981-03-06
IT1145386B (it) 1986-11-05
FR2464252B1 (https=) 1983-05-27
GB2121033B (en) 1984-05-16
IT8049598A0 (it) 1980-09-02
GB2057444B (en) 1983-11-30
BE885018A (fr) 1980-12-31
GB2121033A (en) 1983-12-14
US4283404A (en) 1981-08-11
IL60743A0 (en) 1980-10-26
ES494223A0 (es) 1981-08-01
IL60743A (en) 1984-07-31
JPS5640666A (en) 1981-04-16
GB2057444A (en) 1981-04-01
CA1147735A (en) 1983-06-07
DE3031929A1 (de) 1981-03-26
GB2121032A (en) 1983-12-14

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed