|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
BRPI0608387A2
(pt)
*
|
2006-04-19 |
2009-12-29 |
Boehringer Ingelheim Int |
compostos para o tratamento de doenças inflamatórias
|
|
CL2007001166A1
(es)
|
2006-04-26 |
2008-01-25 |
Piramed Ltd |
Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica
|
|
CN101472930B
(zh)
|
2006-04-26 |
2011-12-14 |
霍夫曼-拉罗奇有限公司 |
用作PI3K抑制剂的噻吩并[3,2-d]嘧啶的衍生物
|
|
PT2041139E
(pt)
|
2006-04-26 |
2012-01-13 |
Hoffmann La Roche |
Compostos farmacêuticos
|
|
BRPI0717923A2
(pt)
*
|
2006-12-07 |
2013-10-22 |
Genentech In |
'' composto, composição farmacêutica, método para tratar um câncer, processo para a produção de uma composição farmacêutica, usos, métodos para inibir ou modular a atividade da lipídeo quinase e kit ' '
|
|
ZA200904531B
(en)
*
|
2006-12-07 |
2010-09-29 |
Hoffmann La Roche |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
|
EP2207781B1
(en)
|
2007-09-24 |
2012-11-28 |
Genentech, Inc. |
Thiazolopyrimidine p13k inhibitor compounds and methods of use
|
|
CA2702518A1
(en)
|
2007-10-19 |
2009-04-23 |
Boehringer Ingelheim International Gmbh |
New piperazino-dihydrothienopyrimidine derivatives
|
|
NZ585346A
(en)
*
|
2007-10-19 |
2011-09-30 |
Boehringer Ingelheim Int |
Substituted piperidino-dihydrothienopyrimidines
|
|
NZ585348A
(en)
|
2007-10-19 |
2012-02-24 |
Boehringer Ingelheim Int |
Heterocycle-substituted piperazino-dihydrothienopyrimidines
|
|
EP2214675B1
(en)
|
2007-10-25 |
2013-11-20 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
AU2010224125B2
(en)
|
2009-03-12 |
2015-05-14 |
Genentech, Inc. |
Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
|
|
EP2435438A1
(en)
|
2009-05-27 |
2012-04-04 |
Genentech, Inc. |
Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
WO2010136491A1
(en)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
AU2010314287A1
(en)
*
|
2009-10-12 |
2012-05-03 |
F. Hoffmann-La Roche Ag |
Combinations of a PI3K inhibitor and a MEK inhibitor
|
|
WO2011130654A1
(en)
|
2010-04-16 |
2011-10-20 |
Genentech, Inc. |
Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
|
US20140004209A1
(en)
|
2010-12-22 |
2014-01-02 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
MX369175B
(es)
|
2013-02-25 |
2019-10-30 |
Genentech Inc |
Métodos para detectar mutantes de akt resistentes a fármacos.
|
|
CN113423711B
(zh)
*
|
2018-10-01 |
2024-03-15 |
建新公司 |
作为udp糖基转移酶抑制剂的噻吩并[3,2-b]吡啶衍生物及其使用方法
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|