NL6603997A - - Google Patents

Info

Publication number
NL6603997A
NL6603997A NL6603997A NL6603997A NL6603997A NL 6603997 A NL6603997 A NL 6603997A NL 6603997 A NL6603997 A NL 6603997A NL 6603997 A NL6603997 A NL 6603997A NL 6603997 A NL6603997 A NL 6603997A
Authority
NL
Netherlands
Application number
NL6603997A
Other versions
NL147732B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6603997A publication Critical patent/NL6603997A/xx
Priority claimed from DE19691918142 external-priority patent/DE1918142A1/de
Priority claimed from DE19691920365 external-priority patent/DE1920365A1/de
Publication of NL147732B publication Critical patent/NL147732B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL666603997A 1965-03-25 1966-03-25 Werkwijze voor het bereiden van een geneesmiddel met een anti-allergische werking en de aldus verkregen gevormde geneesmiddelen, alsmede werkwijze voor het bereiden van geneeskrachtige chromonderivaten. NL147732B (nl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB12626/65A GB1144905A (en) 1965-03-25 1965-03-25 Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof
GB5241465 1965-12-09
GB5374465 1965-12-17
GB37765/68A GB1144906A (en) 1965-03-25 1968-08-07 Bis-phenoxy derivatives
DE19691918142 DE1918142A1 (de) 1969-04-10 1969-04-10 Verfahren zur Herstellung von Bischromonverbindungen
DE19691920365 DE1920365A1 (de) 1969-04-22 1969-04-22 Verfahren zur Herstellung von Bis-Chromonen

Publications (2)

Publication Number Publication Date
NL6603997A true NL6603997A (en:Method) 1966-09-26
NL147732B NL147732B (nl) 1975-11-17

Family

ID=27544127

Family Applications (1)

Application Number Title Priority Date Filing Date
NL666603997A NL147732B (nl) 1965-03-25 1966-03-25 Werkwijze voor het bereiden van een geneesmiddel met een anti-allergische werking en de aldus verkregen gevormde geneesmiddelen, alsmede werkwijze voor het bereiden van geneeskrachtige chromonderivaten.

Country Status (16)

Country Link
US (2) US3419578A (en:Method)
JP (5) JPS5341662B1 (en:Method)
BE (1) BE678175A (en:Method)
CH (1) CH486445A (en:Method)
DE (1) DE1543579C3 (en:Method)
DK (4) DK134646B (en:Method)
FR (1) FR5452M (en:Method)
GB (2) GB1144905A (en:Method)
IL (1) IL25317A (en:Method)
IT (1) IT1047628B (en:Method)
MY (1) MY7000043A (en:Method)
NL (1) NL147732B (en:Method)
NO (3) NO124875B (en:Method)
OA (1) OA03872A (en:Method)
SE (3) SE371185B (en:Method)
YU (1) YU32999B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830920A (en) * 1995-05-05 1998-11-03 Hoffmann-La Roche Inc. Sulfuric acid esters of sugar alcohols

Families Citing this family (89)

* Cited by examiner, † Cited by third party
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US3862175A (en) * 1965-03-25 1975-01-21 Fison House Bis-chromone compounds
GB1144905A (en) * 1965-03-25 1969-03-12 Fisons Pharmaceuticals Ltd Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof
GB1147976A (en) * 1965-12-21 1969-04-10 Fisons Pharmaceuticals Ltd Chromone derivatives
GB1190194A (en) * 1966-07-05 1970-04-29 Fisons Pharmaceuticals Ltd Bis-Phenoxy Compounds and Chromanone and Chromone Derivatives
US3860618A (en) * 1967-08-08 1975-01-14 Philip Saxton Hartley Chromone
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1292601A (en) * 1968-10-30 1972-10-11 Fisons Pharmaceuticals Ltd Bis-(2-carboxy-chromone) compounds, their preparation and pharmaceutical compositions containing them
GB1340512A (en) * 1970-01-21 1973-12-12 Fisons Ltd Production of esters of chromone-2-carboxylic acids
GB1326745A (en) * 1970-04-25 1973-08-15 Fisons Ltd Chromone-2-carboxylic acid derivatives
US3979407A (en) * 1970-07-31 1976-09-07 Allen & Hanburys Limited Chromone derivatives
US4029802A (en) * 1970-08-27 1977-06-14 Fisons Limited The treatment of asthma, hay fever or urticaria
US3968235A (en) 1970-12-14 1976-07-06 Sandoz Ltd. Composition and method for combating insects with alkylenedioxyphenyl derivatives
US3933804A (en) 1970-12-14 1976-01-20 Sandoz Ltd., (Sandoz Ag) Insecticidal 1,3-benzodioxol derivatives
US4105781A (en) * 1970-12-30 1978-08-08 Fujisawa Pharmaceutical Co., Ltd. Chromone compounds and preparation thereof
US3965122A (en) * 1970-12-30 1976-06-22 Fujisawa Pharmaceutical Co., Ltd. Chromone compounds and preparation thereof
US4053628A (en) * 1971-05-12 1977-10-11 Fisons Limited Composition
US3975536A (en) 1971-05-12 1976-08-17 Fisons Limited Composition
GB1399834A (en) * 1971-05-12 1975-07-02 Fisons Ltd Pharmaceutical compositions
US4006245A (en) * 1971-07-29 1977-02-01 Fisons Limited Chemical compounds
GB1384530A (en) * 1971-07-29 1975-02-19 Fisons Ltd Chromone derivatives
GB1410588A (en) * 1971-08-10 1975-10-22 Fisons Ltd Composition
SU469247A3 (ru) * 1972-01-14 1975-04-30 Майлз Лабораториз Инк (Фирма) Способ получени производных хромона
GB1428186A (en) * 1972-06-21 1976-03-17 Fujisawa Pharmaceutical Co Chromone derivatives
FR2196795A1 (en) * 1972-08-25 1974-03-22 Aries Robert Amine salts of bis(carboxychromones) - useful for treatment of dyspnoea and bronchoconstriction
GB1399647A (en) * 1972-12-15 1975-07-02 Fisons Ltd Phenoxyalkoxy-chromone derivatives processes for their preparation and compositions containing them
FR2210398A1 (en) * 1972-12-20 1974-07-12 Aries Robert Bis-(carboxy-chromone) amino ethoxy-ethyl carboxylate salts - useful as a sedative and prophylactic
US3948954A (en) * 1973-01-19 1976-04-06 Fisons Limited Bis-chromone-tetrazole/hydroxamic/carboxylic acids
FR2217004A1 (en) * 1973-02-15 1974-09-06 Aries Robert Sedatives and bronchodilatories - i.e. salts of 1,3-bis(2-carboxychromon-5-yloxy)propanes with 3-hydroxy-2-hydroxymethyl pyridines
FR2230358A2 (en) * 1973-05-25 1974-12-20 Fisons Ltd Cromoglycate contg. solns. - contg. a second therapeutically active cpd. e.g. an antihistamine
US4046910A (en) * 1974-01-28 1977-09-06 The Upjohn Company Dosage schedule
IL48360A (en) * 1974-11-09 1978-12-17 Fisons Ltd Pharmaceutical compositions for the treatment of aphthous stomatitis comprising 1,3-bis-(2-carboxychromon-5-yloxy)-2-carboxychromon-5-yloxy)-2-hydroxypropane
DE2634908A1 (de) * 1974-11-09 1977-04-14 Fisons Ltd Mittel zur behandlung chronischer haut- oder augenerkrankungen
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4145438A (en) * 1975-09-10 1979-03-20 Fisons Limited Method for treatment of eczema or psoriasis
US4067992A (en) * 1975-09-10 1978-01-10 Fisons Limited Method of treating a psychiatric condition
GB1509979A (en) * 1975-11-28 1978-05-10 Fisons Ltd Pharmaceutical compositions containing aspirin or indomethacin
US4097596A (en) * 1976-11-02 1978-06-27 American Home Products Corporation Inhalation therapy for relieving bronchial spasm using quaternary salts of promethazine
GB1557082A (en) * 1977-01-25 1979-12-05 Fisons Ltd Pharmaceutical mixture containing an antiinflammatory
DE2819859A1 (de) * 1977-05-06 1978-11-09 Fisons Ltd Tiermedizinisches behandlungsmittel und inhalationsvorrichtung fuer tiere
US4192860A (en) * 1977-05-06 1980-03-11 Fisons Limited Methods for treating disease conditions
AU522792B2 (en) * 1977-07-19 1982-06-24 Fisons Plc Pressure pack formulation
DE3068213D1 (en) * 1979-09-05 1984-07-19 Glaxo Group Ltd Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them
GB2077100B (en) * 1980-04-30 1985-04-24 Fisons Ltd Pharmaceutical compositions containing cromoglycates
EP0061800B1 (en) 1981-03-24 1985-08-28 FISONS plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
JPS5828509U (ja) * 1981-08-20 1983-02-24 関東電気工事株式会社 分岐箇所用低圧ロ−ラ
US4584315A (en) * 1981-11-16 1986-04-22 The Upjohn Company Method of treating ischemic states
US4447449A (en) * 1981-11-16 1984-05-08 The Upjohn Company Methods of treating ischemic states
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
US4782176A (en) * 1983-01-24 1988-11-01 Hoffmann-La Roche Inc. Phenoxycarboxylic acids
US4581225A (en) * 1984-04-25 1986-04-08 Eli Lilly And Company Sustained release intranasal formulation and method of use thereof
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
US4758678A (en) * 1986-07-18 1988-07-19 Pennwalt Corporation Preparation of 7-(2,3-epoxypropoxy)flavone
US5788983A (en) * 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
US5428033A (en) 1990-10-12 1995-06-27 Merck Frosst Canada, Inc. Saturated hydroxyalkylquinoline acids as leukotriene antagonists
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
GB9317752D0 (en) * 1993-08-26 1993-10-13 Fisons Plc New pharmaceutical use
US5508451A (en) * 1994-07-07 1996-04-16 Hoechst Celanese Corporation Process for the preparation of dialkali metal cromoglycates
CN1088580C (zh) 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
EP0806945B1 (en) * 1994-12-22 2003-04-23 AstraZeneca AB Therapeutic preparation for inhalation containing parathyro d hormone, pth
US6150400A (en) * 1997-06-30 2000-11-21 Presutti Laboratories Method for treating vulvar vestibulitis
US6596284B1 (en) 2002-04-30 2003-07-22 Thomas E. Fleming Treating eczema with a combination of isotonic saline ocean® and nasal mast cell stabilizers
US20050026880A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a cromone for treatment of asthma or chronic obstructive pulmonary disease
US9095621B2 (en) 2008-04-25 2015-08-04 Nektar Therapeutics Oligome-bis-chromonyl compound conjugates
CN105061376A (zh) * 2009-01-29 2015-11-18 通用医疗公司 色甘酸衍生物以及成像和治疗的相关方法
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
TR201000733A2 (tr) 2010-02-02 2011-08-22 Bi̇lgi̇ç Mahmut Flutikazon, tiotropyum ve sodyum kromoglikat içeren farmasötik bileşimler.
EP2764863B1 (en) * 2011-10-03 2020-03-11 National Center for Geriatrics and Gerontology Tau aggregation inhibitor
EP2911664B1 (en) 2012-10-25 2019-05-08 The General Hospital Corporation Combination therapies for the treatment of alzheimer's disease and related disorders
US10058530B2 (en) 2012-10-25 2018-08-28 The General Hospital Corporation Combination therapies for the treatment of Alzheimer's disease and related disorders
US9907799B2 (en) 2013-04-02 2018-03-06 The Doshisha Tau aggregation inhibitor
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
AU2014340182B2 (en) 2013-10-22 2019-05-23 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
EP3725311A1 (en) 2014-02-10 2020-10-21 Respivant Sciences GmbH Methods for the treatment of lung diseases with mast cell stabilizers
EP3653207A1 (en) 2014-02-10 2020-05-20 Respivant Sciences GmbH Mast cell stabilizers treatment for systemic disorders
EP3331522A1 (en) 2015-08-07 2018-06-13 Patara Pharma LLC Methods for the treatment of mast cell related disorders with mast cell stabilizers
US10265296B2 (en) 2015-08-07 2019-04-23 Respivant Sciences Gmbh Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
CN110139646A (zh) 2016-08-31 2019-08-16 瑞思皮万特科学有限责任公司 用于治疗由特发性肺纤维化引起的慢性咳嗽的色甘酸组合物
CA3033079A1 (en) 2016-08-31 2018-03-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
WO2018067341A1 (en) 2016-10-07 2018-04-12 Patara Pharma, LLC Cromolyn compositions for treatment of pulmonary fibrosis
KR20210070232A (ko) 2017-07-20 2021-06-14 아즈테라피즈 인코포레이티드 크로몰린 나트륨 및 이부프로펜의 분말화된 제형
CA3105392A1 (en) 2018-07-02 2020-01-09 The General Hospital Corporation Powdered formulations of cromolyn sodium and .alpha.-lactose
EP3893945A4 (en) 2018-12-10 2022-11-30 The General Hospital Corporation CROMOGLYC ESTERS AND THEIR USES
US20220387408A1 (en) 2019-11-12 2022-12-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of mast cell stabilizer for the treatment of heart failure with preserved ejection fraction
US12458622B2 (en) 2020-04-06 2025-11-04 The General Hospital Corporation Methods of treatment of coronavirus-induced inflammation conditions

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US2769015A (en) * 1954-10-06 1956-10-30 Lab Laroche Navarron Process of preparing 3-methyl-chromone
US3162673A (en) * 1960-12-28 1964-12-22 Union Carbide Corp Bis (aminoaliphatic) carbonates and process for preparation
GB1144905A (en) * 1965-03-25 1969-03-12 Fisons Pharmaceuticals Ltd Substituted bis-(2-carboxy-chromonyl-oxy) derivatives and preparation and pharmaceutical compositions thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830920A (en) * 1995-05-05 1998-11-03 Hoffmann-La Roche Inc. Sulfuric acid esters of sugar alcohols

Also Published As

Publication number Publication date
OA03872A (fr) 1971-12-24
IT1047628B (it) 1980-10-20
DK128245B (da) 1974-03-25
NO124875B (en:Method) 1972-06-19
YU32999B (en) 1976-03-31
US3671625A (en) 1972-06-20
NO137497C (no) 1978-03-08
JPS4843506B1 (en:Method) 1973-12-19
SE372941B (en:Method) 1975-01-20
CH486445A (fr) 1970-02-28
YU177066A (en) 1975-08-31
DK128353B (da) 1974-04-16
GB1144905A (en) 1969-03-12
DE1543579A1 (de) 1969-11-06
US3419578A (en) 1968-12-31
IL25317A (en) 1970-08-19
DK128318B (da) 1974-04-08
DK134646C (en:Method) 1977-05-16
NO124832B (en:Method) 1972-06-12
NO137497B (no) 1977-11-28
JPS5343493B1 (en:Method) 1978-11-20
SE355184B (en:Method) 1973-04-09
DK134646B (da) 1976-12-13
JPS5343492B1 (en:Method) 1978-11-20
GB1144906A (en) 1969-03-12
BE678175A (en:Method) 1966-09-21
MY7000043A (en) 1970-12-31
SE371185B (en:Method) 1974-11-11
JPS5341662B1 (en:Method) 1978-11-06
JPS5341663B1 (en:Method) 1978-11-06
FR5452M (en:Method) 1967-10-16
NL147732B (nl) 1975-11-17
DE1543579B2 (de) 1980-01-03
DE1543579C3 (de) 1980-08-28

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Legal Events

Date Code Title Description
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: FISONS

V4 Discontinued because of reaching the maximum lifetime of a patent