NL301103I1 - tagraxofusp - Google Patents

tagraxofusp

Info

Publication number
NL301103I1
NL301103I1 NL301103C NL301103C NL301103I1 NL 301103 I1 NL301103 I1 NL 301103I1 NL 301103 C NL301103 C NL 301103C NL 301103 C NL301103 C NL 301103C NL 301103 I1 NL301103 I1 NL 301103I1
Authority
NL
Netherlands
Prior art keywords
tagraxofusp
Prior art date
Application number
NL301103C
Other languages
English (en)
Other versions
NL301103I2 (nl
Original Assignee
Scott & White Memorial Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scott & White Memorial Hospital filed Critical Scott & White Memorial Hospital
Publication of NL301103I1 publication Critical patent/NL301103I1/nl
Publication of NL301103I2 publication Critical patent/NL301103I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/202—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
NL301103C 2006-09-07 2021-05-12 tagraxofusp NL301103I2 (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84347106P 2006-09-07 2006-09-07
US93277207P 2007-06-01 2007-06-01
EP07837840.3A EP2063907B1 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
PCT/US2007/019481 WO2008030539A2 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates

Publications (2)

Publication Number Publication Date
NL301103I1 true NL301103I1 (nl) 2021-06-17
NL301103I2 NL301103I2 (nl) 2021-08-02

Family

ID=39157851

Family Applications (1)

Application Number Title Priority Date Filing Date
NL301103C NL301103I2 (nl) 2006-09-07 2021-05-12 tagraxofusp

Country Status (17)

Country Link
US (7) US7763242B2 (nl)
EP (3) EP3207941B3 (nl)
JP (6) JP5550905B2 (nl)
AU (1) AU2007293047B2 (nl)
CA (5) CA2923381A1 (nl)
CY (2) CY1119654T1 (nl)
DK (2) DK3207941T6 (nl)
ES (2) ES2781402T7 (nl)
FR (1) FR21C1017I2 (nl)
HU (2) HUE048356T2 (nl)
LT (2) LT3207941T (nl)
LU (1) LUC00206I2 (nl)
NL (1) NL301103I2 (nl)
PL (2) PL3207941T6 (nl)
PT (1) PT3207941T (nl)
SI (1) SI3207941T1 (nl)
WO (1) WO2008030539A2 (nl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2545942C (en) 2003-11-14 2012-07-10 Lorus Therapeutics Inc. Aryl imidazoles and their use as anti-cancer agents
CA2923381A1 (en) 2006-09-07 2008-03-13 Arthur E. Frankel Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
WO2010027802A2 (en) 2008-08-25 2010-03-11 New York University Methods for treating diabetic wounds
WO2010031185A1 (en) * 2008-09-19 2010-03-25 Protox Therapeutics Inc. Treating cancer stem cells using targeted cargo proteins
CN103002913B (zh) * 2010-02-17 2015-12-16 Csl有限公司 靶向产生i型干扰素的细胞的组合物和方法
EP4056193A1 (en) 2010-06-17 2022-09-14 New York University Therapeutic and cosmetic uses and applications of calreticulin
WO2012019061A2 (en) 2010-08-05 2012-02-09 Stem Centrx, Inc. Novel effectors and methods of use
SG10201506782XA (en) 2010-08-27 2015-10-29 Stem Centrx Inc Notum protein modulators and methods of use
AU2011295715B9 (en) 2010-09-03 2017-02-23 Abbvie Stemcentrx Llc Novel modulators and methods of use
NZ728016A (en) 2010-12-08 2020-06-26 Abbvie Stemcentrx Llc Novel modulators and methods of use
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
WO2013006838A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic combination compositions and uses thereof
US20130058947A1 (en) 2011-09-02 2013-03-07 Stem Centrx, Inc Novel Modulators and Methods of Use
ES2741936T3 (es) 2012-02-24 2020-02-12 Abbvie Stemcentrx Llc Anticuerpos anti-SEZ6 y procedimientos de uso
PL2817338T3 (pl) 2012-02-24 2017-12-29 Abbvie Stemcentrx Llc Modulatory DLL3 i sposoby zastosowania
EP3556400A1 (en) 2013-02-22 2019-10-23 AbbVie Stemcentrx LLC Method of making antidll3-antibody pbd conjugates
EP3892294A1 (en) 2013-08-28 2021-10-13 AbbVie Stemcentrx LLC Site-specific antibody conjugation methods and compositions
CN105792836A (zh) 2013-08-28 2016-07-20 施特姆森特克斯股份有限公司 新型sez6调节剂以及应用方法
WO2015051302A1 (en) 2013-10-04 2015-04-09 Aptose Biosciences Inc. Compositions and methods for treating cancers
CN105813650A (zh) 2013-11-06 2016-07-27 施特姆森特克斯股份有限公司 新型抗-密蛋白抗体和使用方法
WO2015089449A2 (en) 2013-12-12 2015-06-18 Stem Centrx, Inc. Novel anti-dpep3 antibodies and methods of use
MX2016010677A (es) 2014-02-21 2017-04-10 Abbvie Stemcentrx Llc Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma.
LT3137114T (lt) 2014-04-30 2021-03-25 Pfizer Inc. Anti-ptk7 antikūnų ir vaistų konjugatai
TW201617368A (zh) 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗ｍｆｉ２抗體及使用方法
WO2017184942A1 (en) 2016-04-21 2017-10-26 Abbvie Stemcentrx Llc Novel anti-bmpr1b antibodies and methods of use
CN107793481A (zh) * 2016-08-31 2018-03-13 南京传奇生物科技有限公司 一种靶向人cd123的嵌合受体配体及其应用
TW201936190A (zh) 2017-10-30 2019-09-16 加拿大商艾普托斯生物科學公司 用於治療癌症之芳基咪唑
WO2019210179A1 (en) 2018-04-27 2019-10-31 Stemline Therapeutics, Inc. Methods of treating an autoimmune disease with a human interleukin-3 (il-3)-diphtheria toxin conjugate (dt-il3)
WO2019227222A1 (en) * 2018-05-30 2019-12-05 The Governing Council Of The University Of Toronto Methods and kits for identifying a protein associated with receptor-ligand interactions
EP3873476A1 (en) * 2018-10-31 2021-09-08 Stemline Therapeutics, Inc. Combination therapy method of treating myeloproliferative neoplasms with a diphtheria toxin-human interleukin-3 conjugate in combination with other agents
WO2020112642A1 (en) 2018-11-30 2020-06-04 Stemline Therapeutics, Inc. Improved methods of treating myeloproliferative neoplasms with a diphtheria toxin-human interleukin-3 conjugate
EP4061967A1 (en) * 2019-11-21 2022-09-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for diagnosing and treating chronic myelomonocytic leukemia (cmml)
MX2023006805A (es) 2020-12-10 2023-07-06 Stemline Therapeutics Inc Formulacion liofilizada mejorada.

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573529B2 (en) 1982-05-12 1988-06-16 President And Fellows Of Harvard College Hybrid proteins
US5080898A (en) 1982-05-12 1992-01-14 The University Hospital Enzymatically active toxin coupled to a cell-specific ligand
US5668255A (en) 1984-06-07 1997-09-16 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US6022950A (en) 1984-06-07 2000-02-08 Seragen, Inc. Hybrid molecules having translocation region and cell-binding region
US5128326A (en) 1984-12-06 1992-07-07 Biomatrix, Inc. Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
CA2071867A1 (en) 1989-11-06 1991-05-07 Edith Mathiowitz Method for producing protein microspheres
CA2076678C (en) 1990-03-02 1999-09-28 Diane Williams Improved chimeric toxins
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
DE4121547A1 (de) 1991-06-28 1993-01-14 Daimler Benz Ag Mehrschichtisolierfolie
US6162432A (en) 1991-10-07 2000-12-19 Biogen, Inc. Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
DE4140121C2 (de) 1991-12-05 1994-06-30 Manfred Mueller Verfahren zum Herstellen von gefaßten, gegossenen Schmuckstücken
US5912015A (en) 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US5441050A (en) 1992-12-18 1995-08-15 Neoprobe Corporation Radiation responsive surgical instrument
AU5965296A (en) * 1995-05-31 1996-12-18 Regents Of The University Of Minnesota Recombinant polypeptide cytotoxins for cancer treatment
WO1997007788A2 (en) 1995-08-31 1997-03-06 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
US5843633A (en) 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
US20040013664A1 (en) 1997-01-14 2004-01-22 Gentz Reiner L. Tumor necrosis factor receptors 6 alpha & 6 beta
US6004528A (en) 1997-09-18 1999-12-21 Bergstein; Ivan Methods of cancer diagnosis and therapy targeted against the cancer stemline
US7361336B1 (en) 1997-09-18 2008-04-22 Ivan Bergstein Methods of cancer therapy targeted against a cancer stem line
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
WO2001040308A1 (en) 1999-12-03 2001-06-07 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Dendritic cell-specific antibodies
AU2001250030B2 (en) 2000-03-06 2004-11-25 University Of Kentucky Research Foundation Use of a compound that selectively binds to CD123 to impair hematologic cancer progenitor cell
MXPA03007878A (es) 2001-03-02 2004-07-08 Medimmune Inc Metodos de prevencion o tratamiento de alteraciones inflamatorias o autoinmunes mediante la administracion de los antagonistas alfav, beta3 de integrina.
US20030068320A1 (en) 2001-03-02 2003-04-10 Christine Dingivan Methods of administering/dosing CD2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders
KR20120035234A (ko) 2003-04-11 2012-04-13 메디뮨 엘엘씨 재조합 ｉｌ?９ 항체 및 그의 용도
AU2014201901B2 (en) 2006-09-07 2016-05-05 Scott & White Healthcare Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
CA2923381A1 (en) * 2006-09-07 2008-03-13 Arthur E. Frankel Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
US8163279B2 (en) 2007-04-13 2012-04-24 Stemline Therapeutics, Inc. IL3Rα antibody conjugates and uses thereof
US20150038679A1 (en) 2012-02-29 2015-02-05 Ambrx, Inc. Interleukin-3 Polypeptide Conjugates and Their Uses

Also Published As

Publication number Publication date
US20190169251A1 (en) 2019-06-06
CA3153438C (en) 2024-03-12
US20090232767A1 (en) 2009-09-17
CA3007075A1 (en) 2008-03-13
US20080138313A1 (en) 2008-06-12
PL2063907T3 (pl) 2018-06-29
SI3207941T1 (sl) 2020-08-31
LTPA2021507I1 (nl) 2021-06-10
EP3207941B1 (en) 2019-12-25
CA2698595C (en) 2016-07-26
US20180022788A1 (en) 2018-01-25
ES2781402T7 (es) 2021-06-09
US9181317B2 (en) 2015-11-10
FR21C1017I2 (fr) 2022-04-22
JP2016155830A (ja) 2016-09-01
DK2063907T3 (da) 2017-11-13
EP3520806A1 (en) 2019-08-07
US9631006B2 (en) 2017-04-25
AU2007293047B2 (en) 2014-01-09
US7763242B2 (en) 2010-07-27
ES2646545T3 (es) 2017-12-14
WO2008030539A2 (en) 2008-03-13
CA3053981C (en) 2022-07-12
EP2063907B1 (en) 2017-08-09
EP2063907A2 (en) 2009-06-03
NL301103I2 (nl) 2021-08-02
CY1119654T1 (el) 2019-07-10
CA3007075C (en) 2019-10-15
AU2007293047A1 (en) 2008-03-13
JP2020079260A (ja) 2020-05-28
US20160024167A1 (en) 2016-01-28
EP2063907A4 (en) 2011-08-31
CA3153438A1 (en) 2008-03-13
PL3207941T6 (pl) 2020-11-16
LUC00206I2 (nl) 2022-10-07
LTC3207941I2 (nl) 2022-10-10
WO2008030539A3 (en) 2009-04-09
CA2923381A1 (en) 2008-03-13
EP3207941A1 (en) 2017-08-23
EP3207941B3 (en) 2020-08-19
JP6654660B2 (ja) 2020-02-26
HUE048356T2 (hu) 2020-07-28
HUS2100013I1 (hu) 2021-05-28
CA2698595A1 (en) 2008-03-13
US8470307B2 (en) 2013-06-25
US20130315860A1 (en) 2013-11-28
JP5550905B2 (ja) 2014-07-16
DK3207941T3 (da) 2020-03-30
CY1123035T1 (el) 2021-09-14
US20220235108A1 (en) 2022-07-28
CA3053981A1 (en) 2008-03-13
JP2014144967A (ja) 2014-08-14
JP2010502712A (ja) 2010-01-28
FR21C1017I1 (nl) 2021-07-02
US11130792B2 (en) 2021-09-28
JP2018135378A (ja) 2018-08-30
PT3207941T (pt) 2020-04-02
ES2781402T3 (es) 2020-09-01
JP2022065089A (ja) 2022-04-26
PL3207941T3 (pl) 2020-07-27
JP5902223B2 (ja) 2016-04-13
US10259853B2 (en) 2019-04-16
JP6336500B2 (ja) 2018-06-06
LT3207941T (lt) 2020-04-10
DK3207941T6 (da) 2020-11-09
EP3520806B1 (en) 2024-03-20

Similar Documents

Publication Publication Date Title
NL301103I1 (nl) tagraxofusp
DE602006019782D1 (de) Kapselperforationsmodul
DE602007002544D1 (de) Nuancierungsmittel
DE602007008423D1 (de) Flüssigkeitshärtung
DE602007003893D1 (de) Kippambossanordnung
DE602007009650D1 (de) Spiroindolinonderivate
DE602007006947D1 (de) Pyridopyrimidinonderivate
DE602007000258D1 (de) Kassetteneinspannmechanismus
DE602006020192D1 (de) Riemenscheibenanorndung
DE602007001280D1 (de) Getränkeextraktor
AT504580A3 (de) Scan-einrichtung
DE602007008400D1 (de) Kaliummonopersulfatlösungen
DE602007010359D1 (de) Azaspiroderivate
DE602006019150D1 (de) Riemenscheibenanorndung
ATE546437T1 (de) Aminomethyl-4-imidazole
DE502007000218D1 (de) nsetzungen
DE502007002453D1 (de) Kunstoffverdichtergehäuse
DE602007000501D1 (de) Breitbandrichtkoppler
DE602007004080D1 (de) Tintenstrahlaufnehmer
DE602007007460D1 (de) Sehkrafttestsystem
DE602006016174D1 (de) Blisterverpackungsverfahren
DE502007000361D1 (de) Stanznieteinheit
DE502007001629D1 (de) Rfahren
DE602007000333D1 (de) Napfbefestigungsvorrichtung
DE102006045567A8 (de) Crimpstabilisierung