LTC3207941I2 - - Google Patents

Info

Publication number
LTC3207941I2
LTC3207941I2 LTPA2021507C LTPA2021507C LTC3207941I2 LT C3207941 I2 LTC3207941 I2 LT C3207941I2 LT PA2021507 C LTPA2021507 C LT PA2021507C LT PA2021507 C LTPA2021507 C LT PA2021507C LT C3207941 I2 LTC3207941 I2 LT C3207941I2
Authority
LT
Lithuania
Application number
LTPA2021507C
Original Assignee
Scott & White Memorial Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scott & White Memorial Hospital filed Critical Scott & White Memorial Hospital
Publication of LTPA2021507I1 publication Critical patent/LTPA2021507I1/lt
Publication of LTC3207941I2 publication Critical patent/LTC3207941I2/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5403IL-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/202IL-3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
LTPA2021507C 2006-09-07 2021-05-12 LTC3207941I2 (lt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84347106P 2006-09-07 2006-09-07
US93277207P 2007-06-01 2007-06-01
PCT/US2007/019481 WO2008030539A2 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
EP07837840.3A EP2063907B1 (en) 2006-09-07 2007-09-07 Methods and compositions based on diphtheria toxin-interleukin-3 conjugates

Publications (2)

Publication Number Publication Date
LTPA2021507I1 LTPA2021507I1 (lt) 2021-06-10
LTC3207941I2 true LTC3207941I2 (lt) 2022-10-10

Family

ID=39157851

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17151480.5T LT3207941T (lt) 2006-09-07 2007-09-07 Būdai ir kompozicijos difterijos toksino ir interleukino 3 konjugatų pagrindu
LTPA2021507C LTC3207941I2 (lt) 2006-09-07 2021-05-12

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP17151480.5T LT3207941T (lt) 2006-09-07 2007-09-07 Būdai ir kompozicijos difterijos toksino ir interleukino 3 konjugatų pagrindu

Country Status (17)

Country Link
US (7) US7763242B2 (lt)
EP (3) EP2063907B1 (lt)
JP (6) JP5550905B2 (lt)
AU (1) AU2007293047B2 (lt)
CA (5) CA2923381A1 (lt)
CY (2) CY1119654T1 (lt)
DK (2) DK3207941T6 (lt)
ES (2) ES2781402T7 (lt)
FR (1) FR21C1017I2 (lt)
HU (2) HUE048356T2 (lt)
LT (2) LT3207941T (lt)
LU (1) LUC00206I2 (lt)
NL (1) NL301103I2 (lt)
PL (2) PL2063907T3 (lt)
PT (1) PT3207941T (lt)
SI (1) SI3207941T1 (lt)
WO (1) WO2008030539A2 (lt)

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EP2352526A1 (en) * 2008-09-19 2011-08-10 Protox Therapeutics Inc. Treating cancer stem cells using targeted cargo proteins
JP6018507B2 (ja) * 2010-02-17 2016-11-02 シーエスエル、リミテッド I型インターフェロン産生細胞を標的化するための組成物及び方法
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WO2012019061A2 (en) 2010-08-05 2012-02-09 Stem Centrx, Inc. Novel effectors and methods of use
KR20140018837A (ko) 2010-08-27 2014-02-13 스템 센트알엑스 인코포레이티드 노텀 단백질 조절 인자 및 사용 방법
US9458231B2 (en) 2010-09-03 2016-10-04 Stemcentrx, Inc. Modulators and methods of use
TWI585106B (zh) 2010-12-08 2017-06-01 艾伯維史坦森特瑞斯有限責任公司 新穎調節劑及其使用方法
SA112330278B1 (ar) 2011-02-18 2015-10-09 ستيم سينتركس، انك. مواد ضابطة جديدة وطرق للاستخدام
CA2840989A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic combination compositions and uses thereof
US20130058947A1 (en) 2011-09-02 2013-03-07 Stem Centrx, Inc Novel Modulators and Methods of Use
EP2817338B1 (en) 2012-02-24 2017-07-26 AbbVie Stemcentrx LLC Dll3 modulators and methods of use
MX2014010094A (es) 2012-02-24 2014-09-16 Stem Centrx Inc Anticuerpos anti-homologo relacionado con las convulsiones 6 (anti-sez6) y metodos de uso.
AU2014218730B2 (en) 2013-02-22 2018-12-13 Abbvie Stemcentrx Llc Novel antibody conjugates and uses thereof
CA2922547C (en) 2013-08-28 2020-03-10 Stemcentrx, Inc. Site-specific antibody conjugation methods and compositions
WO2015031541A1 (en) 2013-08-28 2015-03-05 Stem Centrx, Inc. Novel sez6 modulators and methods of use
JP6946000B2 (ja) 2013-10-04 2021-10-06 アプトース バイオサイエンシーズ, インコーポレイテッド がんの治療用組成物及び方法
PE20160870A1 (es) 2013-11-06 2016-09-09 Abbvie Stemcentrx Llc Anticuerpos anti-claudina novedosos y metodos de uso
JP2017500028A (ja) 2013-12-12 2017-01-05 アッヴィ・ステムセントルクス・エル・エル・シー 新規の抗dpep3抗体および使用方法
EP3107576A4 (en) 2014-02-21 2017-09-06 Abbvie Stemcentrx LLC Anti-dll3 antibodies and drug conjugates for use in melanoma
RU2708075C2 (ru) 2014-04-30 2019-12-04 Пфайзер Инк. Конъюгаты анти-ртк7 антитело-лекарственное средство
TW201617368A (zh) 2014-09-05 2016-05-16 史坦森特瑞斯公司 新穎抗mfi2抗體及使用方法
AU2017254674A1 (en) 2016-04-21 2018-11-01 Abbvie Stemcentrx Llc Novel anti-BMPR1B antibodies and methods of use
CN107793481A (zh) * 2016-08-31 2018-03-13 南京传奇生物科技有限公司 一种靶向人cd123的嵌合受体配体及其应用
WO2019089511A1 (en) 2017-10-30 2019-05-09 Aptose Biosciences Inc. Aryl imidazoles for the treatment of cancer
US20210361744A1 (en) * 2018-04-27 2021-11-25 Stemline Therapeutics, Inc. Methods of Treating an Autoimmune Disease with a Human Interleukin-3 (IL-3)-Diphtheria Toxin Conjugate (DT-IL3)
EP3802834A4 (en) * 2018-05-30 2022-08-03 The Governing Council of the University of Toronto METHODS AND KITS FOR IDENTIFYING A PROTEIN ASSOCIATED WITH RECEPTOR-LIGAND INTERACTIONS
BR112021007945A2 (pt) 2018-10-31 2021-08-03 Stemline Therapeutics, Inc. método de terapia de combinação para tratar neoplasmas mieloproliferativos com um conjugado de toxina de difteria-interleucina-3 humana em combinação com outros agentes
WO2020112642A1 (en) 2018-11-30 2020-06-04 Stemline Therapeutics, Inc. Improved methods of treating myeloproliferative neoplasms with a diphtheria toxin-human interleukin-3 conjugate
WO2021099573A1 (en) * 2019-11-21 2021-05-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for diagnosing and treating chronic myelomonocytic leukemia (cmml)
KR20230146515A (ko) 2020-12-10 2023-10-19 스템라인 테라퓨틱스, 인코포레이티드 개선된 동결건조 제형

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Also Published As

Publication number Publication date
EP3207941A1 (en) 2017-08-23
CY1119654T1 (el) 2019-07-10
EP2063907A2 (en) 2009-06-03
JP2010502712A (ja) 2010-01-28
DK3207941T3 (da) 2020-03-30
JP2022065089A (ja) 2022-04-26
NL301103I1 (nl) 2021-06-17
CA2923381A1 (en) 2008-03-13
US10259853B2 (en) 2019-04-16
ES2781402T7 (es) 2021-06-09
JP6654660B2 (ja) 2020-02-26
US9181317B2 (en) 2015-11-10
EP3520806B1 (en) 2024-03-20
US20190169251A1 (en) 2019-06-06
US11130792B2 (en) 2021-09-28
HUS2100013I1 (hu) 2021-05-28
PT3207941T (pt) 2020-04-02
JP2014144967A (ja) 2014-08-14
CA3007075A1 (en) 2008-03-13
LTPA2021507I1 (lt) 2021-06-10
US7763242B2 (en) 2010-07-27
EP3520806A1 (en) 2019-08-07
US20130315860A1 (en) 2013-11-28
US20180022788A1 (en) 2018-01-25
CA2698595A1 (en) 2008-03-13
US20080138313A1 (en) 2008-06-12
PL3207941T3 (pl) 2020-07-27
NL301103I2 (nl) 2021-08-02
JP2018135378A (ja) 2018-08-30
CA2698595C (en) 2016-07-26
DK3207941T6 (da) 2020-11-09
HUE048356T2 (hu) 2020-07-28
JP6336500B2 (ja) 2018-06-06
CA3153438C (en) 2024-03-12
ES2781402T3 (es) 2020-09-01
EP2063907A4 (en) 2011-08-31
FR21C1017I2 (fr) 2022-04-22
CA3153438A1 (en) 2008-03-13
WO2008030539A3 (en) 2009-04-09
US20220235108A1 (en) 2022-07-28
AU2007293047B2 (en) 2014-01-09
ES2646545T3 (es) 2017-12-14
AU2007293047A1 (en) 2008-03-13
WO2008030539A2 (en) 2008-03-13
FR21C1017I1 (lt) 2021-07-02
EP3207941B1 (en) 2019-12-25
JP5550905B2 (ja) 2014-07-16
CY1123035T1 (el) 2021-09-14
LT3207941T (lt) 2020-04-10
US20090232767A1 (en) 2009-09-17
US8470307B2 (en) 2013-06-25
JP2020079260A (ja) 2020-05-28
EP3207941B3 (en) 2020-08-19
LUC00206I2 (lt) 2022-10-07
CA3053981A1 (en) 2008-03-13
SI3207941T1 (sl) 2020-08-31
CA3007075C (en) 2019-10-15
PL3207941T6 (pl) 2020-11-16
DK2063907T3 (da) 2017-11-13
JP5902223B2 (ja) 2016-04-13
JP2016155830A (ja) 2016-09-01
US20160024167A1 (en) 2016-01-28
EP2063907B1 (en) 2017-08-09
US9631006B2 (en) 2017-04-25
CA3053981C (en) 2022-07-12
PL2063907T3 (pl) 2018-06-29

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