NL2000337A1 - Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. - Google Patents

Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. Download PDF

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Publication number
NL2000337A1
NL2000337A1 NL2000337A NL2000337A NL2000337A1 NL 2000337 A1 NL2000337 A1 NL 2000337A1 NL 2000337 A NL2000337 A NL 2000337A NL 2000337 A NL2000337 A NL 2000337A NL 2000337 A1 NL2000337 A1 NL 2000337A1
Authority
NL
Netherlands
Prior art keywords
pyrrole
isopropyl
amino
pyrimidine
methoxyphenyl
Prior art date
Application number
NL2000337A
Other languages
English (en)
Dutch (nl)
Inventor
Tracy Lee Boyden
Feng Guo
Susan Deborah Lagreca
Douglas Alan Lorenz
Ravi Mysore Shanker
Franzanne Vreeland
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NL2000337A1 publication Critical patent/NL2000337A1/nl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
NL2000337A 2005-12-09 2006-11-27 Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum. NL2000337A1 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74907005P 2005-12-09 2005-12-09
US74907005 2005-12-09

Publications (1)

Publication Number Publication Date
NL2000337A1 true NL2000337A1 (nl) 2007-06-12

Family

ID=38123252

Family Applications (1)

Application Number Title Priority Date Filing Date
NL2000337A NL2000337A1 (nl) 2005-12-09 2006-11-27 Zouten, voorgeneesmiddelen en formuleringen van 1-[5- (4-amino-7-isopropyl-7H-pyrrool[2,3-D]pyrimidine-5-carbonyl)-2- methoxyfenyl]-3- (2,4-dichloorfenyl)-ureum.

Country Status (8)

Country Link
AR (1) AR058293A1 (es)
DO (1) DOP2006000271A (es)
GT (1) GT200600496A (es)
NL (1) NL2000337A1 (es)
PE (1) PE20071037A1 (es)
TW (1) TW200733965A (es)
UY (1) UY29991A1 (es)
WO (1) WO2007066189A2 (es)

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CA2699335A1 (en) * 2007-10-19 2009-04-23 Abbott Gmbh & Co. Kg. Solid dispersion product containing n-aryl urea-based compound
BRPI0818340A2 (pt) * 2007-10-19 2015-04-22 Abbott Gmbh & Co Kg Produto de dispersão sólida de fármacos baseados em n-aril uréia
ES2570429T3 (es) * 2008-10-16 2016-05-18 Univ California Inhibidores de heteroaril quinasa de anillo condensado
CN102892768A (zh) 2009-12-30 2013-01-23 艾科尔公司 被取代的吡咯并氨基嘧啶化合物
CN103037843A (zh) * 2010-06-23 2013-04-10 麦它波莱克斯股份有限公司 5-乙基-2-{4-[4-(4-四唑-1-基-苯氧甲基)-噻唑-2-基]-哌啶-1-基}-嘧啶的组合物
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
CA2846496C (en) 2011-09-02 2020-07-14 The Regents Of The University Of California Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
US20140004192A1 (en) * 2012-04-13 2014-01-02 Ziopharm Oncology, Inc. Pharmaceutical formulations of indibulin and uses thereof
ME03300B (me) 2012-06-13 2019-07-20 Incyte Holdings Corp Supsтituisana triciklična jedinjenja као inhibiтori fgfr
WO2014026125A1 (en) 2012-08-10 2014-02-13 Incyte Corporation Pyrazine derivatives as fgfr inhibitors
JP2015532287A (ja) 2012-09-26 2015-11-09 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア Ｉｒｅ１の調節
US9266892B2 (en) 2012-12-19 2016-02-23 Incyte Holdings Corporation Fused pyrazoles as FGFR inhibitors
DK2986610T5 (en) 2013-04-19 2018-12-10 Incyte Holdings Corp BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
US10851105B2 (en) 2014-10-22 2020-12-01 Incyte Corporation Bicyclic heterocycles as FGFR4 inhibitors
EA038045B1 (ru) 2015-02-20 2021-06-28 Инсайт Корпорейшн Бициклические гетероциклы в качестве ингибиторов fgfr
WO2016134294A1 (en) 2015-02-20 2016-08-25 Incyte Corporation Bicyclic heterocycles as fgfr4 inhibitors
MA41551A (fr) 2015-02-20 2017-12-26 Incyte Corp Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
CN107722012B (zh) * 2016-08-11 2020-05-29 斯福瑞（南通）制药有限公司 制备4-氯-7H-吡咯并[2,3-d]嘧啶的方法
AR111960A1 (es) 2017-05-26 2019-09-04 Incyte Corp Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
EA202092649A1 (ru) 2018-05-04 2021-06-21 Инсайт Корпорейшн Соли ингибитора fgfr
US11466004B2 (en) 2018-05-04 2022-10-11 Incyte Corporation Solid forms of an FGFR inhibitor and processes for preparing the same
US11628162B2 (en) 2019-03-08 2023-04-18 Incyte Corporation Methods of treating cancer with an FGFR inhibitor
US11591329B2 (en) 2019-07-09 2023-02-28 Incyte Corporation Bicyclic heterocycles as FGFR inhibitors
IL291901A (en) 2019-10-14 2022-06-01 Incyte Corp Bicyclyl heterocycles as fgr suppressors
WO2021076728A1 (en) 2019-10-16 2021-04-22 Incyte Corporation Bicyclic heterocycles as fgfr inhibitors
WO2021113479A1 (en) 2019-12-04 2021-06-10 Incyte Corporation Tricyclic heterocycles as fgfr inhibitors
KR20220131900A (ko) 2019-12-04 2022-09-29 인사이트 코포레이션 Fgfr 억제제의 유도체
AR126102A1 (es) 2021-06-09 2023-09-13 Incyte Corp Heterociclos tricíclicos como inhibidores de fgfr

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0901786T3 (da) * 1997-08-11 2007-10-08 Pfizer Prod Inc Faste farmaceutiske dispersioner med foröget biotilgængelighed
UA80171C2 (en) * 2002-12-19 2007-08-27 Pfizer Prod Inc Pyrrolopyrimidine derivatives

Also Published As

Publication number Publication date
TW200733965A (en) 2007-09-16
GT200600496A (es) 2007-07-17
AR058293A1 (es) 2008-01-30
DOP2006000271A (es) 2007-08-15
PE20071037A1 (es) 2007-11-19
WO2007066189A3 (en) 2008-08-14
WO2007066189A2 (en) 2007-06-14
UY29991A1 (es) 2007-07-31

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