NL193282C - Bloeddrukverlagend prolinederivaat en werkwijze voor het bereiden van een bloeddrukverlagend geneesmiddel. - Google Patents
Bloeddrukverlagend prolinederivaat en werkwijze voor het bereiden van een bloeddrukverlagend geneesmiddel. Download PDFInfo
- Publication number
- NL193282C NL193282C NL8202472A NL8202472A NL193282C NL 193282 C NL193282 C NL 193282C NL 8202472 A NL8202472 A NL 8202472A NL 8202472 A NL8202472 A NL 8202472A NL 193282 C NL193282 C NL 193282C
- Authority
- NL
- Netherlands
- Prior art keywords
- mixture
- proline
- added
- cyclohexanecarbonyl
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9400281 | 1981-06-19 | ||
| JP56094002A JPS57209270A (en) | 1981-06-19 | 1981-06-19 | Proline derivative |
| JP13782381 | 1981-09-03 | ||
| JP56137823A JPS5839661A (ja) | 1981-09-03 | 1981-09-03 | プロリン誘導体の製法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8202472A NL8202472A (nl) | 1983-01-17 |
| NL193282B NL193282B (nl) | 1999-01-04 |
| NL193282C true NL193282C (nl) | 1999-05-06 |
Family
ID=26435270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8202472A NL193282C (nl) | 1981-06-19 | 1982-06-18 | Bloeddrukverlagend prolinederivaat en werkwijze voor het bereiden van een bloeddrukverlagend geneesmiddel. |
Country Status (19)
| Country | Link |
|---|---|
| KR (1) | KR890000769B1 (sv) |
| AT (1) | AT377496B (sv) |
| CA (1) | CA1235120A (sv) |
| CH (1) | CH651825A5 (sv) |
| DE (1) | DE3222779A1 (sv) |
| DK (1) | DK156054C (sv) |
| ES (2) | ES8307216A1 (sv) |
| FI (1) | FI75804C (sv) |
| FR (1) | FR2508040B1 (sv) |
| GB (1) | GB2102412B (sv) |
| HU (1) | HU188177B (sv) |
| IL (1) | IL65954A (sv) |
| IT (1) | IT1157053B (sv) |
| MX (2) | MX155724A (sv) |
| NL (1) | NL193282C (sv) |
| NO (1) | NO156408C (sv) |
| PT (1) | PT75076B (sv) |
| SE (1) | SE453595B (sv) |
| SU (1) | SU1316556A3 (sv) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6354321A (ja) * | 1985-03-27 | 1988-03-08 | Ajinomoto Co Inc | 血糖降下剤 |
| KR870007114A (ko) * | 1986-01-21 | 1987-08-14 | 우에노 기미오 | 티올 에스테르 유도체의 안정된 고형제 |
| ZA896851B (en) | 1988-09-14 | 1990-06-27 | Hoffmann La Roche | Use of ace-inhibitors |
| EP0634175B1 (de) * | 1993-07-15 | 2001-01-10 | F. Hoffmann-La Roche Ag | Pharmazeutische Kombination, die einen Hemmer des Renin-Angiotensin-Systems und einen Endothelin-Antagonisten enthält |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA802420B (en) * | 1979-05-18 | 1981-04-29 | Squibb & Sons Inc | Aminoacyl derivatives of mercaptoacyl amino acids |
-
1981
- 1981-12-29 AT AT0558581A patent/AT377496B/de not_active IP Right Cessation
-
1982
- 1982-05-26 GB GB08215345A patent/GB2102412B/en not_active Expired
- 1982-05-28 CA CA000404054A patent/CA1235120A/en not_active Expired
- 1982-06-02 IL IL65954A patent/IL65954A/xx not_active IP Right Cessation
- 1982-06-16 IT IT67772/82A patent/IT1157053B/it active
- 1982-06-16 SU SU823450352A patent/SU1316556A3/ru active
- 1982-06-16 NO NO821997A patent/NO156408C/no not_active IP Right Cessation
- 1982-06-16 FI FI822171A patent/FI75804C/sv not_active IP Right Cessation
- 1982-06-16 MX MX193189A patent/MX155724A/es unknown
- 1982-06-16 MX MX010799A patent/MX171888B/es unknown
- 1982-06-17 DK DK273082A patent/DK156054C/da not_active IP Right Cessation
- 1982-06-17 CH CH3751/82A patent/CH651825A5/de not_active IP Right Cessation
- 1982-06-17 HU HU821976A patent/HU188177B/hu not_active IP Right Cessation
- 1982-06-18 PT PT75076A patent/PT75076B/pt not_active IP Right Cessation
- 1982-06-18 ES ES513277A patent/ES8307216A1/es not_active Expired
- 1982-06-18 NL NL8202472A patent/NL193282C/nl not_active IP Right Cessation
- 1982-06-18 DE DE19823222779 patent/DE3222779A1/de active Granted
- 1982-06-18 SE SE8203814A patent/SE453595B/sv not_active IP Right Cessation
- 1982-06-19 KR KR8202740A patent/KR890000769B1/ko active
- 1982-06-21 FR FR8210796A patent/FR2508040B1/fr not_active Expired
-
1983
- 1983-03-14 ES ES520582A patent/ES8403868A1/es not_active Expired
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR900008004B1 (ko) | 펩티다제 억제물의 제조방법 | |
| CA2032559C (en) | Endothelin antagonistic cyclic pentapeptides | |
| SK63194A3 (en) | Peptide derivatives | |
| EP0273689B1 (en) | Derivatives of n-(2-alkyl-3-mercapto-glutaryl) alpha-amino acids and their use as collagenase inhibitors | |
| JPH03386B2 (sv) | ||
| HU181087B (en) | Process for producing mercapto-acyl-dipeptides | |
| EP0577775A1 (en) | Anti-thrombotic peptides and pseudopeptides | |
| EP0042291A2 (en) | Methods and compositions for preparation of H-Arg-X-Z-Y-Tyr-R | |
| ES2274106T3 (es) | Derivados de pirano como inhibidores tanto de ace como de nep. | |
| NL193282C (nl) | Bloeddrukverlagend prolinederivaat en werkwijze voor het bereiden van een bloeddrukverlagend geneesmiddel. | |
| EP0009898A1 (en) | Novel anti-hypertensive mercaptoacylamino acid derivatives, their preparation and use | |
| US4420490A (en) | Substituted phenylacetic acid amide compounds | |
| Roubini et al. | Pseudopeptide analogs of substance P and leucine enkephalinamide containing the. psi.(methyleneoxy) modification: synthesis and biological activity | |
| AT390619B (de) | Verfahren zur herstellung von neuen prolinderivaten | |
| EP0080283B1 (en) | N-carboxyalkylproline-containing tripeptides | |
| US4456594A (en) | N-Carboxyalkylproline-containing tripeptides | |
| FI64349B (fi) | Foerfarande foer framstaellning av ett terapeutiskt anvaendbart l-pyroglutamyl-l-histidyl-glycin och dess salter | |
| JPH11509850A (ja) | ドラスタチン１５の製法及びその中間体 | |
| WO1988005049A1 (en) | Novel compounds | |
| KR890000770B1 (ko) | 프롤린 유도체의 제법 | |
| AU611269B2 (en) | Peptides with pharmaceutical activity | |
| IE65539B1 (en) | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same | |
| JPH0136465B2 (sv) | ||
| JPH0667902B2 (ja) | ３―チオプロピオン酸誘導体の製造法 | |
| KR100236473B1 (ko) | 항암 효과를 갖는 아자펩타이드 파네실 전이효소 저해제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1B | A search report has been drawn up | ||
| A85 | Still pending on 85-01-01 | ||
| BC | A request for examination has been filed | ||
| V1 | Lapsed because of non-payment of the annual fee |
Effective date: 20000101 |