NL192326C - Werkwijze voor het bereiden van een geneesmiddel, waarbij een gezuiverd, ontgift endotoxine samen met een drager en eventueel andere toevoegingen in een voor therapeutische toediening geschikte vorm wordt gebracht. - Google Patents

Werkwijze voor het bereiden van een geneesmiddel, waarbij een gezuiverd, ontgift endotoxine samen met een drager en eventueel andere toevoegingen in een voor therapeutische toediening geschikte vorm wordt gebracht. Download PDF

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Publication number
NL192326C
NL192326C NL8402515A NL8402515A NL192326C NL 192326 C NL192326 C NL 192326C NL 8402515 A NL8402515 A NL 8402515A NL 8402515 A NL8402515 A NL 8402515A NL 192326 C NL192326 C NL 192326C
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NL
Netherlands
Prior art keywords
rde
endotoxin
purified
standard
response
Prior art date
Application number
NL8402515A
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English (en)
Dutch (nl)
Other versions
NL8402515A (nl
NL192326B (nl
Original Assignee
Ribi Immunochem Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribi Immunochem Research Inc filed Critical Ribi Immunochem Research Inc
Publication of NL8402515A publication Critical patent/NL8402515A/nl
Publication of NL192326B publication Critical patent/NL192326B/xx
Application granted granted Critical
Publication of NL192326C publication Critical patent/NL192326C/nl

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/05Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NL8402515A 1983-08-26 1984-08-16 Werkwijze voor het bereiden van een geneesmiddel, waarbij een gezuiverd, ontgift endotoxine samen met een drager en eventueel andere toevoegingen in een voor therapeutische toediening geschikte vorm wordt gebracht. NL192326C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52696783A 1983-08-26 1983-08-26
US52696783 1983-08-26

Publications (3)

Publication Number Publication Date
NL8402515A NL8402515A (nl) 1985-03-18
NL192326B NL192326B (nl) 1997-02-03
NL192326C true NL192326C (nl) 1997-06-04

Family

ID=24099553

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8402515A NL192326C (nl) 1983-08-26 1984-08-16 Werkwijze voor het bereiden van een geneesmiddel, waarbij een gezuiverd, ontgift endotoxine samen met een drager en eventueel andere toevoegingen in een voor therapeutische toediening geschikte vorm wordt gebracht.

Country Status (22)

Country Link
JP (1) JPS6072825A (de)
KR (1) KR880002223B1 (de)
AT (1) AT389228B (de)
AU (1) AU554039B2 (de)
BE (1) BE900377A (de)
CA (1) CA1225592A (de)
CH (1) CH660125A5 (de)
DE (2) DE3448164C2 (de)
DK (1) DK389384A (de)
ES (1) ES8606883A1 (de)
FI (1) FI843204A (de)
FR (1) FR2550945B1 (de)
GB (1) GB2147806B (de)
HU (1) HU191713B (de)
IL (1) IL72675A (de)
IN (1) IN157910B (de)
IT (1) IT1177974B (de)
NL (1) NL192326C (de)
NO (1) NO843243L (de)
NZ (1) NZ209233A (de)
SE (1) SE8404090L (de)
ZA (1) ZA846309B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629722A (en) * 1984-07-12 1986-12-16 Ribi Immunochem Research, Inc. Method of inhibiting the onset of acute radiation syndrome
US4803070A (en) * 1986-04-15 1989-02-07 Ribi Immunochem Research Inc. Immunological emulsion adjuvants for polysaccharide vaccines
US4806352A (en) * 1986-04-15 1989-02-21 Ribi Immunochem Research Inc. Immunological lipid emulsion adjuvant
DE10115310A1 (de) * 2001-03-28 2002-10-10 Nodar A Daniela Bakteriophagen-Präparation
KR100868443B1 (ko) * 2002-05-27 2008-11-11 주식회사 포스코 폭과 길이가 가변 조정되는 런치박스 제작장치

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2160326B1 (de) * 1971-11-19 1975-02-07 Anvar
BE793260A (fr) * 1971-12-24 1973-06-22 Pasteur Institut Agent immunostimulant, medicaments le contenant et procede de fabrication de cet agent immunostimulant
NL7507376A (nl) * 1974-06-20 1975-12-23 Anvar Werkwijze voor de bereiding van bacteriele prepa- raten met anti-tumor, antivirale en adjuvans-acti- viteiten.
FR2393065A1 (fr) * 1977-05-31 1978-12-29 Merieux Inst Procede de separation de lipides d'endotoxines bacteriennes et notamment d'endotoxine de bordetella pertussis
US4435386A (en) * 1982-05-26 1984-03-06 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436727A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4436728A (en) * 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product

Also Published As

Publication number Publication date
BE900377A (fr) 1985-02-18
FR2550945B1 (fr) 1988-09-16
SE8404090L (sv) 1985-02-27
ES535124A0 (es) 1986-05-01
CA1225592A (en) 1987-08-18
NO843243L (no) 1985-02-27
DE3448164C2 (de) 1987-06-25
AU3221584A (en) 1985-02-28
ZA846309B (en) 1985-03-27
IT8448757A1 (it) 1986-02-24
ATA273384A (de) 1989-04-15
IT1177974B (it) 1987-09-03
KR880002223B1 (ko) 1988-10-20
IT8448757A0 (it) 1984-08-24
AU554039B2 (en) 1986-08-07
ES8606883A1 (es) 1986-05-01
DK389384A (da) 1985-02-27
JPH0556326B2 (de) 1993-08-19
IL72675A (en) 1988-04-29
DK389384D0 (da) 1984-08-13
GB8420612D0 (en) 1984-09-19
NL8402515A (nl) 1985-03-18
AT389228B (de) 1989-11-10
DE3431058C2 (de) 1987-06-11
FI843204A (fi) 1985-02-27
FI843204A0 (fi) 1984-08-14
KR850001696A (ko) 1985-04-01
NZ209233A (en) 1987-11-27
DE3431058A1 (de) 1985-03-07
GB2147806B (en) 1986-10-22
HU191713B (en) 1987-03-30
JPS6072825A (ja) 1985-04-24
GB2147806A (en) 1985-05-22
IN157910B (de) 1986-07-19
CH660125A5 (de) 1987-03-31
FR2550945A1 (fr) 1985-03-01
NL192326B (nl) 1997-02-03
IL72675A0 (en) 1984-11-30
HUT34887A (en) 1985-05-28
SE8404090D0 (sv) 1984-08-14

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NL192326C (nl) Werkwijze voor het bereiden van een geneesmiddel, waarbij een gezuiverd, ontgift endotoxine samen met een drager en eventueel andere toevoegingen in een voor therapeutische toediening geschikte vorm wordt gebracht.
KITAGAWA et al. Chemical Studies on Cellular Components of Hemophilus pertussis II. Isolation of Toxic Lipopolysaccharide

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BT A notification was added to the application dossier and made available to the public
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20040816