NL190485B - ALFA-FLUORMETHYL-ALFA-AMINOALCANIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING ONE OR MORE SUCH COMPOUNDS, AND METHOD FOR PREPARING THE COMPOUNDS. - Google Patents

ALFA-FLUORMETHYL-ALFA-AMINOALCANIC ACID DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING ONE OR MORE SUCH COMPOUNDS, AND METHOD FOR PREPARING THE COMPOUNDS.

Info

Publication number
NL190485B
NL190485B NLAANVRAGE7805981,A NL7805981A NL190485B NL 190485 B NL190485 B NL 190485B NL 7805981 A NL7805981 A NL 7805981A NL 190485 B NL190485 B NL 190485B
Authority
NL
Netherlands
Prior art keywords
alfa
compounds
aminoalcanic
fluormethyl
preparing
Prior art date
Application number
NLAANVRAGE7805981,A
Other languages
Dutch (nl)
Other versions
NL190485C (en
NL7805981A (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NL7805981A publication Critical patent/NL7805981A/en
Publication of NL190485B publication Critical patent/NL190485B/en
Application granted granted Critical
Publication of NL190485C publication Critical patent/NL190485C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
NLAANVRAGE7805981,A 1977-06-01 1978-06-01 alpha-Fluoromethyl-alpha-aminoalkanoic acid derivative, pharmaceutical composition containing one or more such compounds, and method of preparing the compounds. NL190485C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (3)

Publication Number Publication Date
NL7805981A NL7805981A (en) 1978-12-05
NL190485B true NL190485B (en) 1993-10-18
NL190485C NL190485C (en) 1994-03-16

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7805981,A NL190485C (en) 1977-06-01 1978-06-01 alpha-Fluoromethyl-alpha-aminoalkanoic acid derivative, pharmaceutical composition containing one or more such compounds, and method of preparing the compounds.

Country Status (26)

Country Link
JP (1) JPS5416423A (en)
AR (1) AR223463A1 (en)
AT (1) AT360509B (en)
AU (1) AU518479B2 (en)
CA (1) CA1120040A (en)
CH (1) CH639639A5 (en)
DD (1) DD138651A5 (en)
DE (1) DE2824116A1 (en)
DK (1) DK149841C (en)
ES (1) ES470296A1 (en)
FI (1) FI66840C (en)
FR (1) FR2392958A1 (en)
GB (1) GB1602525A (en)
GR (1) GR64495B (en)
HK (1) HK18184A (en)
HU (1) HU181911B (en)
IE (1) IE46983B1 (en)
IT (1) IT1104709B (en)
LU (1) LU79750A1 (en)
NL (1) NL190485C (en)
NO (1) NO147382C (en)
NZ (1) NZ187377A (en)
PL (1) PL115731B1 (en)
PT (1) PT68102B (en)
SE (1) SE7806440L (en)
YU (1) YU129178A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
EP0007600B1 (en) * 1978-07-24 1983-05-11 Merck & Co. Inc. Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
AU544990B2 (en) * 1980-06-16 1985-06-27 Merrell Pharmaceuticals Inc. Antiprotozal composition containing amino compounds
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
NO781892L (en) 1978-12-04
PL115731B1 (en) 1981-04-30
GB1602525A (en) 1981-11-11
IT1104709B (en) 1985-10-28
AT360509B (en) 1981-01-12
NO147382C (en) 1983-03-30
ATA393278A (en) 1980-06-15
DK149841C (en) 1987-04-21
AU518479B2 (en) 1981-10-01
HU181911B (en) 1983-11-28
JPS5416423A (en) 1979-02-07
FI66840B (en) 1984-08-31
FR2392958A1 (en) 1978-12-29
LU79750A1 (en) 1979-02-02
SE7806440L (en) 1978-12-02
JPS641474B2 (en) 1989-01-11
PL207242A1 (en) 1979-04-23
NL190485C (en) 1994-03-16
AR223463A1 (en) 1981-08-31
IT7849637A0 (en) 1978-05-31
DK237978A (en) 1979-01-19
PT68102B (en) 1982-06-08
IE46983B1 (en) 1983-11-16
NL7805981A (en) 1978-12-05
FI781674A (en) 1978-12-02
NO147382B (en) 1982-12-20
ES470296A1 (en) 1979-09-16
DE2824116C2 (en) 1989-04-27
PT68102A (en) 1978-06-01
CH639639A5 (en) 1983-11-30
HK18184A (en) 1984-03-09
DK149841B (en) 1986-10-13
DD138651A5 (en) 1979-11-14
FR2392958B1 (en) 1980-10-24
DE2824116A1 (en) 1978-12-14
NZ187377A (en) 1981-05-15
GR64495B (en) 1980-03-31
IE781078L (en) 1978-12-01
YU129178A (en) 1983-01-21
CA1120040A (en) 1982-03-16
AU3658678A (en) 1979-12-06
FI66840C (en) 1984-12-10

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V1 Lapsed because of non-payment of the annual fee

Effective date: 19980101