IT1104709B - ALPHA-FLUOROMETHYL-ALPHA-AMINO ALCANOIC ACIDS - Google Patents

ALPHA-FLUOROMETHYL-ALPHA-AMINO ALCANOIC ACIDS

Info

Publication number
IT1104709B
IT1104709B IT49637/78A IT4963778A IT1104709B IT 1104709 B IT1104709 B IT 1104709B IT 49637/78 A IT49637/78 A IT 49637/78A IT 4963778 A IT4963778 A IT 4963778A IT 1104709 B IT1104709 B IT 1104709B
Authority
IT
Italy
Prior art keywords
alpha
fluoromethyl
amino
alcanoic acids
alcanoic
Prior art date
Application number
IT49637/78A
Other languages
Italian (it)
Other versions
IT7849637A0 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IT7849637A0 publication Critical patent/IT7849637A0/en
Application granted granted Critical
Publication of IT1104709B publication Critical patent/IT1104709B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
IT49637/78A 1977-06-01 1978-05-31 ALPHA-FLUOROMETHYL-ALPHA-AMINO ALCANOIC ACIDS IT1104709B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (2)

Publication Number Publication Date
IT7849637A0 IT7849637A0 (en) 1978-05-31
IT1104709B true IT1104709B (en) 1985-10-28

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49637/78A IT1104709B (en) 1977-06-01 1978-05-31 ALPHA-FLUOROMETHYL-ALPHA-AMINO ALCANOIC ACIDS

Country Status (26)

Country Link
JP (1) JPS5416423A (en)
AR (1) AR223463A1 (en)
AT (1) AT360509B (en)
AU (1) AU518479B2 (en)
CA (1) CA1120040A (en)
CH (1) CH639639A5 (en)
DD (1) DD138651A5 (en)
DE (1) DE2824116A1 (en)
DK (1) DK149841C (en)
ES (1) ES470296A1 (en)
FI (1) FI66840C (en)
FR (1) FR2392958A1 (en)
GB (1) GB1602525A (en)
GR (1) GR64495B (en)
HK (1) HK18184A (en)
HU (1) HU181911B (en)
IE (1) IE46983B1 (en)
IT (1) IT1104709B (en)
LU (1) LU79750A1 (en)
NL (1) NL190485C (en)
NO (1) NO147382C (en)
NZ (1) NZ187377A (en)
PL (1) PL115731B1 (en)
PT (1) PT68102B (en)
SE (1) SE7806440L (en)
YU (1) YU129178A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
ATE3282T1 (en) * 1978-07-24 1983-05-15 Merck & Co. Inc. ALPHA-DIFLUOROMETHYL-ALPHA-AMINO ACIDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
ZA813953B (en) * 1980-06-16 1982-06-30 Merrell Dow Pharma Method of inhibiting the growth of protozoa
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
DE2824116C2 (en) 1989-04-27
FR2392958B1 (en) 1980-10-24
NO147382B (en) 1982-12-20
NO147382C (en) 1983-03-30
SE7806440L (en) 1978-12-02
PL207242A1 (en) 1979-04-23
LU79750A1 (en) 1979-02-02
DK149841B (en) 1986-10-13
AR223463A1 (en) 1981-08-31
HK18184A (en) 1984-03-09
CA1120040A (en) 1982-03-16
AU3658678A (en) 1979-12-06
DK149841C (en) 1987-04-21
DD138651A5 (en) 1979-11-14
FI66840B (en) 1984-08-31
NO781892L (en) 1978-12-04
NL7805981A (en) 1978-12-05
FI66840C (en) 1984-12-10
AT360509B (en) 1981-01-12
FI781674A (en) 1978-12-02
GR64495B (en) 1980-03-31
YU129178A (en) 1983-01-21
NL190485B (en) 1993-10-18
NL190485C (en) 1994-03-16
GB1602525A (en) 1981-11-11
DE2824116A1 (en) 1978-12-14
IT7849637A0 (en) 1978-05-31
ATA393278A (en) 1980-06-15
IE46983B1 (en) 1983-11-16
HU181911B (en) 1983-11-28
AU518479B2 (en) 1981-10-01
JPS641474B2 (en) 1989-01-11
PT68102A (en) 1978-06-01
PT68102B (en) 1982-06-08
FR2392958A1 (en) 1978-12-29
NZ187377A (en) 1981-05-15
JPS5416423A (en) 1979-02-07
CH639639A5 (en) 1983-11-30
IE781078L (en) 1978-12-01
PL115731B1 (en) 1981-04-30
DK237978A (en) 1979-01-19
ES470296A1 (en) 1979-09-16

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960521