NL179582C - Werkwijze voor de bereiding van benzodiazepinederivaten. - Google Patents

Werkwijze voor de bereiding van benzodiazepinederivaten.

Info

Publication number
NL179582C
NL179582C NLAANVRAGE7311507,A NL7311507A NL179582C NL 179582 C NL179582 C NL 179582C NL 7311507 A NL7311507 A NL 7311507A NL 179582 C NL179582 C NL 179582C
Authority
NL
Netherlands
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
NLAANVRAGE7311507,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7311507A (fi
NL179582B (nl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL7311507A publication Critical patent/NL7311507A/xx
Publication of NL179582B publication Critical patent/NL179582B/xx
Application granted granted Critical
Publication of NL179582C publication Critical patent/NL179582C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NLAANVRAGE7311507,A 1972-08-21 1973-08-21 Werkwijze voor de bereiding van benzodiazepinederivaten. NL179582C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28221772A 1972-08-21 1972-08-21
US35981473A 1973-05-14 1973-05-14

Publications (3)

Publication Number Publication Date
NL7311507A NL7311507A (fi) 1974-02-25
NL179582B NL179582B (nl) 1986-05-01
NL179582C true NL179582C (nl) 1986-10-01

Family

ID=26961312

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7311507,A NL179582C (nl) 1972-08-21 1973-08-21 Werkwijze voor de bereiding van benzodiazepinederivaten.

Country Status (24)

Country Link
JP (1) JPS5911589B2 (fi)
AR (1) AR198108A1 (fi)
AT (1) AT341527B (fi)
AU (1) AU472777B2 (fi)
CA (1) CA1012535A (fi)
CH (1) CH578544A5 (fi)
DD (1) DD107040A5 (fi)
DE (1) DE2340159A1 (fi)
DK (1) DK155326C (fi)
ES (1) ES418014A1 (fi)
FI (1) FI57939C (fi)
FR (1) FR2197003B1 (fi)
GB (1) GB1392681A (fi)
HU (1) HU170153B (fi)
IE (1) IE38091B1 (fi)
IL (1) IL42947A (fi)
LU (1) LU68269A1 (fi)
NL (1) NL179582C (fi)
NO (1) NO139481C (fi)
PH (1) PH13640A (fi)
PL (1) PL99162B1 (fi)
SE (1) SE408302B (fi)
SU (1) SU550980A3 (fi)
YU (1) YU219873A (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5334792A (en) * 1976-09-13 1978-03-31 Scherico Ltd Production of 1*44 benzodiazepines and 1*44 benzodiazepinee22ones
CN113149915B (zh) * 2021-03-01 2024-03-15 中国科学院成都有机化学有限公司 一种合成氯硝西泮化合物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1136709B (de) * 1959-12-10 1962-09-20 Hoffmann La Roche Verfahren zur Herstellung von 2-Oxo-1, 2-dihydro-1, 4-benzodiazepinen
CH537393A (de) * 1969-10-16 1973-05-31 Hoffmann La Roche Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten
BE785962A (fr) * 1971-07-08 1973-01-08 Hoffmann La Roche Procede pour la preparation de derives de benzodiazepine

Also Published As

Publication number Publication date
FR2197003B1 (fi) 1978-01-13
IE38091L (en) 1974-02-21
DK155326B (da) 1989-03-28
NO139481B (no) 1978-12-11
DE2340159C2 (fi) 1989-01-19
SU550980A3 (ru) 1977-03-15
CA1012535A (en) 1977-06-21
FR2197003A1 (fi) 1974-03-22
NL7311507A (fi) 1974-02-25
AR198108A1 (es) 1974-05-31
AU5918073A (en) 1975-02-13
JPS5911589B2 (ja) 1984-03-16
LU68269A1 (fi) 1975-05-21
FI57939C (fi) 1980-11-10
SE408302B (sv) 1979-06-05
YU219873A (en) 1982-06-30
NO139481C (no) 1979-03-21
DD107040A5 (fi) 1974-07-12
FI57939B (fi) 1980-07-31
DK155326C (da) 1989-08-14
IL42947A (en) 1977-01-31
PH13640A (en) 1980-08-18
JPS4956992A (fi) 1974-06-03
HU170153B (fi) 1977-04-28
PL99162B1 (pl) 1978-06-30
CH578544A5 (fi) 1976-08-13
IE38091B1 (en) 1977-12-21
AU472777B2 (en) 1976-06-03
NL179582B (nl) 1986-05-01
IL42947A0 (en) 1973-11-28
GB1392681A (en) 1975-04-30
DE2340159A1 (de) 1974-03-07
AT341527B (de) 1978-02-10
ATA720773A (de) 1977-06-15
ES418014A1 (es) 1976-03-16

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Legal Events

Date Code Title Description
BC A request for examination has been filed
A85 Still pending on 85-01-01
SNR Assignments of patents or rights arising from examined patent applications

Owner name: F. HOFFMANN-LA ROCHE AG

V1 Lapsed because of non-payment of the annual fee