NL1027115A1 - Aminozuren met affiniteit voor het alfa-2-delta-proteïne. - Google Patents
Aminozuren met affiniteit voor het alfa-2-delta-proteïne.Info
- Publication number
- NL1027115A1 NL1027115A1 NL1027115A NL1027115A NL1027115A1 NL 1027115 A1 NL1027115 A1 NL 1027115A1 NL 1027115 A NL1027115 A NL 1027115A NL 1027115 A NL1027115 A NL 1027115A NL 1027115 A1 NL1027115 A1 NL 1027115A1
- Authority
- NL
- Netherlands
- Prior art keywords
- affinity
- alpha
- amino acids
- delta protein
- delta
- Prior art date
Links
- 101000914947 Bungarus multicinctus Long neurotoxin homolog TA-bm16 Proteins 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
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- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
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- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50595303P | 2003-09-25 | 2003-09-25 | |
US50595303 | 2003-09-25 | ||
US50744303P | 2003-09-30 | 2003-09-30 | |
US50744303 | 2003-09-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL1027115A1 true NL1027115A1 (nl) | 2005-03-29 |
NL1027115C2 NL1027115C2 (nl) | 2005-09-07 |
Family
ID=34396281
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1027115A NL1027115C2 (nl) | 2003-09-25 | 2004-09-24 | Aminozuren met affiniteit voor het alfa-2-delta-proteïne. |
NL1029821A NL1029821C2 (nl) | 2003-09-25 | 2005-08-26 | Aminozuren met affiniteit voor het alfa-2-delta-proteïne. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1029821A NL1029821C2 (nl) | 2003-09-25 | 2005-08-26 | Aminozuren met affiniteit voor het alfa-2-delta-proteïne. |
Country Status (27)
Country | Link |
---|---|
US (3) | US7179934B2 (nl) |
EP (1) | EP1667957A2 (nl) |
JP (2) | JP4001349B2 (nl) |
KR (2) | KR100768974B1 (nl) |
AP (1) | AP2006003544A0 (nl) |
AR (1) | AR046022A1 (nl) |
AU (1) | AU2004276072A1 (nl) |
BR (1) | BRPI0414781A (nl) |
CA (1) | CA2540208A1 (nl) |
CO (1) | CO5680413A2 (nl) |
CR (1) | CR8290A (nl) |
EA (1) | EA200600467A1 (nl) |
EC (1) | ECSP066450A (nl) |
IL (1) | IL173764A0 (nl) |
IS (1) | IS8308A (nl) |
MA (1) | MA28048A1 (nl) |
MX (1) | MXPA06003395A (nl) |
NL (2) | NL1027115C2 (nl) |
NO (1) | NO20061812L (nl) |
OA (1) | OA13258A (nl) |
PA (1) | PA8613101A1 (nl) |
PE (1) | PE20050434A1 (nl) |
RS (1) | RS20060210A (nl) |
TN (1) | TNSN06095A1 (nl) |
TW (1) | TW200528420A (nl) |
UY (1) | UY28533A1 (nl) |
WO (1) | WO2005030700A2 (nl) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006008612A2 (en) * | 2004-07-09 | 2006-01-26 | Warner-Lambert Company Llc | Preparation of beta-amino acids having affinity for the alpha-2-delta protein |
EP1863780A1 (en) * | 2005-03-24 | 2007-12-12 | Pharmacia & Upjohn Company LLC | Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein |
US20090286875A1 (en) * | 2005-11-17 | 2009-11-19 | Pfizer, Inc. | Isocystene derivatives for the treatment of pain |
EP1993529A1 (en) * | 2006-03-06 | 2008-11-26 | Pfizer Products Inc. | Alpha-2-delta ligands for non-restorative sleep |
AR061728A1 (es) * | 2006-06-30 | 2008-09-17 | Pfizer Prod Inc | Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1 |
EP1903027A1 (en) | 2006-09-13 | 2008-03-26 | Novartis AG | Process for preparing biaryl substituted 4-amino-butyric acid or derivatives thereof and their use in the production of NEP inhibitors |
US20110130454A1 (en) * | 2009-11-24 | 2011-06-02 | Xenoport, Inc. | Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
US20110124705A1 (en) * | 2009-11-24 | 2011-05-26 | Xenoport, Inc. | Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof |
WO2014069626A1 (ja) * | 2012-11-01 | 2014-05-08 | 協和発酵キリン株式会社 | ピリミドジアゼピノン化合物の製造方法 |
US10610512B2 (en) | 2014-06-26 | 2020-04-07 | Island Breeze Systems Ca, Llc | MDI related products and methods of use |
CN116351339A (zh) * | 2022-06-07 | 2023-06-30 | 北京先通国际医药科技股份有限公司 | 一种液体组合物的生产设备及其制备方法和用途 |
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US195251A (en) * | 1877-09-18 | Improvement in coffee-roasters | ||
US5968942A (en) * | 1992-08-25 | 1999-10-19 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
US5578606A (en) * | 1992-10-30 | 1996-11-26 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors |
US6153650A (en) * | 1996-10-23 | 2000-11-28 | Warner-Lambert Company | Substituted gamma aminobutyric acids as pharmaceutical agents |
US6306909B1 (en) * | 1997-03-12 | 2001-10-23 | Queen's University At Kingston | Anti-epileptogenic agents |
TR200103587T2 (tr) * | 1999-06-10 | 2002-04-22 | Warner Lambert Company | Mono-ve çift ikame edilmiş 3-propil gama aminobutirik asitler. |
NI200300043A (es) * | 2002-03-28 | 2003-11-05 | Warner Lambert Co | AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA. |
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US7419981B2 (en) * | 2002-08-15 | 2008-09-02 | Pfizer Inc. | Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor |
US20050043406A1 (en) * | 2003-08-22 | 2005-02-24 | Pfizer Inc | Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss |
GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
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2004
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- 2004-09-13 WO PCT/IB2004/002985 patent/WO2005030700A2/en active Application Filing
- 2004-09-13 KR KR1020067005872A patent/KR100768974B1/ko not_active IP Right Cessation
- 2004-09-13 BR BRPI0414781-2A patent/BRPI0414781A/pt not_active Application Discontinuation
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- 2004-09-13 JP JP2006527500A patent/JP4001349B2/ja not_active Expired - Fee Related
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- 2004-09-23 TW TW093128802A patent/TW200528420A/zh unknown
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2005
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2006
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- 2006-04-25 NO NO20061812A patent/NO20061812L/no not_active Application Discontinuation
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2007
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