NI201000052A - Composición de zibotentan que contiene manitol y/o celulosa microcristalina. - Google Patents

Composición de zibotentan que contiene manitol y/o celulosa microcristalina.

Info

Publication number
NI201000052A
NI201000052A NI201000052A NI201000052A NI201000052A NI 201000052 A NI201000052 A NI 201000052A NI 201000052 A NI201000052 A NI 201000052A NI 201000052 A NI201000052 A NI 201000052A NI 201000052 A NI201000052 A NI 201000052A
Authority
NI
Nicaragua
Prior art keywords
microcrystalline cellulose
zibotentan
composition
containing mannitol
mannitol
Prior art date
Application number
NI201000052A
Other languages
English (en)
Inventor
David Blyth John
John Day Andrew
James Lennon Kieran
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40534840&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NI201000052(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NI201000052A publication Critical patent/NI201000052A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describe una composición farmacéutica que contiene N - (3 - metoxi - 5 - metilpirazin - 2 - il) - 2 - (4 - [1, 3, 4 - oxadiazol - 2 - il] fenil) piridin - 3 - sulfonamida con manitol y/o celulosa microcristalina.
NI201000052A 2007-10-12 2010-04-12 Composición de zibotentan que contiene manitol y/o celulosa microcristalina. NI201000052A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97973607P 2007-10-12 2007-10-12
US8911808P 2008-08-15 2008-08-15

Publications (1)

Publication Number Publication Date
NI201000052A true NI201000052A (es) 2011-03-24

Family

ID=40534840

Family Applications (1)

Application Number Title Priority Date Filing Date
NI201000052A NI201000052A (es) 2007-10-12 2010-04-12 Composición de zibotentan que contiene manitol y/o celulosa microcristalina.

Country Status (35)

Country Link
US (2) US8168221B2 (es)
EP (2) EP2209501B1 (es)
JP (1) JP2011500548A (es)
KR (1) KR20100099113A (es)
CN (1) CN101896210A (es)
AR (1) AR068845A1 (es)
AT (1) ATE536893T1 (es)
AU (1) AU2008309385B2 (es)
BR (1) BRPI0818323A2 (es)
CA (1) CA2701385A1 (es)
CL (1) CL2008003022A1 (es)
CO (1) CO6270344A2 (es)
CR (1) CR11363A (es)
CU (1) CU20100064A7 (es)
CY (1) CY1112433T1 (es)
DK (1) DK2209501T3 (es)
DO (1) DOP2010000105A (es)
EA (1) EA201000545A1 (es)
ES (1) ES2377426T3 (es)
HK (1) HK1143095A1 (es)
HR (1) HRP20120085T1 (es)
IL (1) IL204953A0 (es)
MX (1) MX2010003989A (es)
NI (1) NI201000052A (es)
NZ (1) NZ585310A (es)
PE (1) PE20091032A1 (es)
PL (1) PL2209501T3 (es)
PT (1) PT2209501E (es)
SG (1) SG182138A1 (es)
SI (1) SI2209501T1 (es)
SV (1) SV2010003529A (es)
TW (1) TW200924768A (es)
UY (1) UY31385A1 (es)
WO (1) WO2009047565A2 (es)
ZA (1) ZA201002477B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1644336T3 (pl) 2003-06-06 2011-07-29 Fibrogen Inc Związki heteroarylowe zawierające azot i ich zastosowanie w zwiększaniu poziomu endogennej erytropoetyny
TW200924768A (en) 2007-10-12 2009-06-16 Astrazeneca Ab Composition
CN101822796B (zh) * 2010-03-17 2012-01-04 山西仟源制药有限公司 一种银冰含片及制备方法和应用
EP2568973A2 (en) * 2010-05-11 2013-03-20 Sensient Colors LLC Film coating composition and methods of making and using the same
JO3753B1 (ar) 2011-10-14 2021-01-31 Otsuka Pharma Co Ltd قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه
JP6363993B2 (ja) * 2012-04-27 2018-07-25 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ コーティングを有する錠剤および該錠剤の製造
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
SI3470397T1 (sl) 2012-07-16 2022-07-29 Fibrogen, Inc. Kristalinične oblike zaviralca prolil hidroksilaze
DK3003284T3 (da) * 2013-06-06 2020-03-30 Fibrogen Inc Farmaceutiske formuleringer af en hif-hydroxylase-inhibitor
TW202203971A (zh) * 2020-03-31 2022-02-01 日商衛材R&D企管股份有限公司 錠劑、醫藥及其等之製造方法以及套組

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674794A (en) * 1970-03-18 1972-07-04 Ciba Geigy Corp Certain-3-pyridine-sulfonamide derivatives
UA58494C2 (uk) * 1995-06-07 2003-08-15 Зенека Лімітед Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну
US5783705A (en) * 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
PL197843B1 (pl) * 1997-04-28 2008-05-30 Encysive Pharmaceuticals Inc Farmaceutycznie dopuszczalne sole metali alkalicznych ze związkami sulfonoamidowymi, środek farmaceutyczny, zastosowanie farmaceutycznie dopuszczalnych soli metali alkalicznych ze związkami sulfonoamidowymi, sposób wytwarzania liofilizowanego proszku i sposób wytwarzania farmaceutycznie dopuszczalnych soli metali alkalicznych ze związkami sulfonoamidowymi
EP1203580A4 (en) * 1999-06-18 2004-06-30 Takeda Chemical Industries Ltd SOLID PREPARATIONS WITH FAST DISINTEGRATION
JP2001058944A (ja) * 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
CN1615135A (zh) 2001-11-13 2005-05-11 法马西亚公司 磺酰胺前药如帕瑞考昔的口服剂型
GB0219660D0 (en) * 2002-08-23 2002-10-02 Astrazeneca Ab Therapeutic use
WO2004026233A2 (en) * 2002-09-20 2004-04-01 Merck & Co., Inc. Mannitol formulation for integrin receptor antagonist
GB0223854D0 (en) 2002-10-12 2002-11-20 Astrazeneca Ab Therapeutic treatment
GB0320806D0 (en) 2003-09-05 2003-10-08 Astrazeneca Ab Therapeutic treatment
US7772232B2 (en) 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
GB0425854D0 (en) 2004-11-25 2004-12-29 Astrazeneca Ab Therapeutic treatment
CN101032464A (zh) * 2007-04-01 2007-09-12 杨喜鸿 含有利莫那班和聚乙烯吡咯烷酮的组合物、固体分散体及其制备和药物应用
TW200924768A (en) 2007-10-12 2009-06-16 Astrazeneca Ab Composition

Also Published As

Publication number Publication date
DOP2010000105A (es) 2010-08-15
ZA201002477B (en) 2010-12-29
BRPI0818323A2 (pt) 2017-05-16
WO2009047565A3 (en) 2009-11-26
CY1112433T1 (el) 2015-12-09
CA2701385A1 (en) 2009-04-16
HRP20120085T1 (hr) 2012-02-29
AU2008309385B2 (en) 2011-10-20
ATE536893T1 (de) 2011-12-15
PT2209501E (pt) 2012-02-03
SI2209501T1 (sl) 2012-03-30
US8168221B2 (en) 2012-05-01
PL2209501T3 (pl) 2012-03-30
SV2010003529A (es) 2010-09-13
EP2433620A1 (en) 2012-03-28
CN101896210A (zh) 2010-11-24
US20120177705A1 (en) 2012-07-12
AU2008309385A1 (en) 2009-04-16
IL204953A0 (en) 2010-11-30
WO2009047565A2 (en) 2009-04-16
DK2209501T3 (da) 2012-02-27
EP2209501A2 (en) 2010-07-28
ES2377426T3 (es) 2012-03-27
EP2209501B1 (en) 2011-12-14
AR068845A1 (es) 2009-12-09
KR20100099113A (ko) 2010-09-10
UY31385A1 (es) 2009-05-29
CU20100064A7 (es) 2011-10-05
MX2010003989A (es) 2010-04-27
CR11363A (es) 2010-07-14
CO6270344A2 (es) 2011-04-20
CL2008003022A1 (es) 2010-07-23
JP2011500548A (ja) 2011-01-06
HK1143095A1 (en) 2010-12-24
SG182138A1 (en) 2012-07-30
US20090099203A1 (en) 2009-04-16
NZ585310A (en) 2012-02-24
TW200924768A (en) 2009-06-16
PE20091032A1 (es) 2009-08-15
EA201000545A1 (ru) 2010-10-29

Similar Documents

Publication Publication Date Title
NI201000052A (es) Composición de zibotentan que contiene manitol y/o celulosa microcristalina.
CL2011002697A1 (es) Compuestos derivados de 3-[4-(oxo-dihidropiridin)bencil]-1,3-oxazin-ona hidratados, inhibidores 11beta-hsd1; composicion farmaceutica que los comprende; y su uso en el tratamiento de la diabetes
CL2008002199A1 (es) Compuestos derivados de 1,3-oxazin-2-ona; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad asociada con la actividad de la 11beta-hidroxiesteroide deshidrogenasa tipo 1 (11beta-hsd1) tales como dislipidemia, hiperlipidemia, hipertension, obesidad y enfermedad cardiovascular, entre otras.
PE20121820A1 (es) (2s,3r)-n-(2-((3-piridinil)metil)-1-azabiciclo[2.2.2]oct-3-il)benzofuran-2-carboxamida, formas de sales novedosas de ella, y metodos de uso de ella
TW200833324A (en) Sulfonamide derivatives
EA201070598A1 (ru) Терапевтическое применение соединений, обладающих комбинированной активностью в отношении sert, 5-htи 5-ht
CL2008001157A1 (es) Compuestos derivados de quinolina-carboxamida, antagonistas de p2y12; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; composicion de una combinacion de dichos compuestos; y uso del compuesto en el tratamiento de trastornos cardiovasculares, tromboembolismo, infarto agudo al miocardio.
AR062860A1 (es) Combinaciones terapeuticas 482
MX2010004028A (es) 4-[3-(4-ciclopropancarbonil-piperacin-1-carbonil)-4-fluoro-bencil ]-2h-ftalacin-1-ona.
AR068369A1 (es) Sal de xinafoato de n4-[(2,2-difluor-4h-benzo[1,4]oxazin-3-on)-6-il]-5-fluor-n2-[3-(metilaminocarbonilmetilenoxi)-fenil]2,4-pirimidindiamina"
EA201001334A1 (ru) Твёрдый препарат гидрохлорида карипразина для перорального введения
CL2007001391A1 (es) Compuestos derivados de pirrolidinas sustituidas, inhibidores del factor xa y/o inhibidores sobre la serina proteasa; composicion farmaceutica que comprende a dichos compuestos; proedimiento para preparar la composicon farmaceutica; y uso de los compuestos preparar un medicamneto con un efecto antitrombotico
ATE466838T1 (de) Sulfonamid-derivate als lebercarnitin-palmitoyl- transferase-hemmer
CL2008002049A1 (es) Compuestos derivados de aminoindol macrociclicos; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c.
CL2007000918A1 (es) Compuestos derivados de enfumafungina, inhibidores de (1,3)-beta-d-glucanosintetasa; composicion farmaceutica; y uso para tratar una infeccion fungica.
CO6361993A2 (es) Compuestos de 4-[2-(2-fluorofenoximetil)fenil]piperidina
EA201170680A1 (ru) Ингибиторы акт и p70 s6-киназы
RS53138B (en) 4- [2- (4-METHYLPHENYLSULPHANYL) PHENYL] PIPERIDINE FOR THE TREATMENT OF INJURED INTENTION SYNDROME (IBS).
CO6321285A2 (es) Uso de 3,11b-cis- dihidrotetrabenazina en el tratamiento de la esclerosis multiple y la mielitis autoinmunitaria
BRPI0720684A2 (pt) composto, medicamento, composição farmacêutica que contém e uso do composto
EA201171207A1 (ru) Биодоступные композиции аморфного альфа-(n-сульфонамидо)ацетамидного соединения
UY30552A1 (es) Combinaciones farmacologiicas en base a derivados sustituidos de la n-(5-{2-[1,1-dimetil-propilamino]-1-hidroxi-metil}-2-hidroxi-fenil)-metansulfonamida y aplicaciones
EA201070737A1 (ru) Терапевтическое применение соединений, обладающих аффинностью к переносчику серотонина, рецепторам серотонина и переносчику норадреналина
NO20080053L (no) Etanolaminsalt av N-(3-metoksy-5-metylpyrazin-2yl)-2-(4-(1,3,4-oksadiazol-2-yl)fenyl)pyridin-3-sulfonamid
NO20092695L (no) Profylaktisk eller terapeutisk middel for alopeki