MY8700890A - New cis-bicyclo (3.3.0) octane derivatives, pharmaceutical compositions containing them and processes for the preparation of these compounds and pharmaceutical compositions. - Google Patents

New cis-bicyclo (3.3.0) octane derivatives, pharmaceutical compositions containing them and processes for the preparation of these compounds and pharmaceutical compositions.

Info

Publication number
MY8700890A
MY8700890A MY890/87A MY8700890A MY8700890A MY 8700890 A MY8700890 A MY 8700890A MY 890/87 A MY890/87 A MY 890/87A MY 8700890 A MY8700890 A MY 8700890A MY 8700890 A MY8700890 A MY 8700890A
Authority
MY
Malaysia
Prior art keywords
compounds
pharmaceutical compositions
bicyclo
processes
preparation
Prior art date
Application number
MY890/87A
Other languages
English (en)
Inventor
Bohlke Horst
Loschen Gerriet
Michel-Nee-Lambert Gudrun
Muller Bernd
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of MY8700890A publication Critical patent/MY8700890A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/59Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4018Esters of cycloaliphatic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
MY890/87A 1981-11-21 1987-12-30 New cis-bicyclo (3.3.0) octane derivatives, pharmaceutical compositions containing them and processes for the preparation of these compounds and pharmaceutical compositions. MY8700890A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3146278A DE3146278C2 (de) 1981-11-21 1981-11-21 cis-Bicyclo[3.3.0]octanderivate, diese enthaltende Arzneimittel und Verfahren zur Herstellung dieser Verbindungen

Publications (1)

Publication Number Publication Date
MY8700890A true MY8700890A (en) 1987-12-31

Family

ID=6146953

Family Applications (1)

Application Number Title Priority Date Filing Date
MY890/87A MY8700890A (en) 1981-11-21 1987-12-30 New cis-bicyclo (3.3.0) octane derivatives, pharmaceutical compositions containing them and processes for the preparation of these compounds and pharmaceutical compositions.

Country Status (21)

Country Link
US (1) US4510323A (fr)
EP (1) EP0080061B1 (fr)
JP (1) JPS5892637A (fr)
AT (1) ATE11668T1 (fr)
AU (1) AU556560B2 (fr)
CA (1) CA1202968A (fr)
DD (1) DD207196A5 (fr)
DE (2) DE3146278C2 (fr)
DK (1) DK155934C (fr)
ES (1) ES8308299A1 (fr)
GR (1) GR77643B (fr)
HK (1) HK40488A (fr)
HU (1) HU187814B (fr)
IE (1) IE53785B1 (fr)
MY (1) MY8700890A (fr)
PL (1) PL137185B1 (fr)
PT (1) PT75694B (fr)
SG (1) SG5788G (fr)
SU (1) SU1225482A3 (fr)
YU (1) YU42604B (fr)
ZA (1) ZA826928B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3408699A1 (de) * 1984-03-08 1985-09-12 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3914735A1 (de) * 1989-05-05 1990-11-08 Gruenenthal Gmbh Pharmakologisch wirksame ester, diese enthaltende arzneimittel und die herstellung dieser ester und arzneimittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201699A (en) * 1922-06-02 1923-08-09 Joseph Gardner Improvements in mechanical lubricators
IT1113341B (it) * 1978-03-31 1986-01-20 Ono Pharmaceutical Co Analoghi della 6,9-metano-pgi2
CA1201712A (fr) * 1980-02-28 1986-03-11 Paul A. Aristoff Analogues de la carbacycline
JPS56145239A (en) * 1980-04-11 1981-11-11 Sumitomo Chem Co Ltd Novel bicyclooctane derivative and its preparation

Also Published As

Publication number Publication date
ATE11668T1 (de) 1985-02-15
JPS5892637A (ja) 1983-06-02
PL137185B1 (en) 1986-05-31
DK155934B (da) 1989-06-05
ES517545A0 (es) 1983-08-16
ES8308299A1 (es) 1983-08-16
IE822252L (en) 1983-04-21
ZA826928B (en) 1983-11-30
DE3262233D1 (en) 1985-03-21
DE3146278A1 (de) 1983-06-01
SU1225482A3 (ru) 1986-04-15
DK513982A (da) 1983-05-22
DD207196A5 (de) 1984-02-22
YU257882A (en) 1985-03-20
SG5788G (en) 1989-06-02
EP0080061B1 (fr) 1985-02-06
GR77643B (fr) 1984-09-25
AU8881382A (en) 1983-05-26
PT75694B (de) 1985-01-10
DE3146278C2 (de) 1984-10-31
PL239099A1 (en) 1983-05-23
IE53785B1 (en) 1989-02-15
HK40488A (en) 1988-06-10
PT75694A (de) 1982-11-01
DK155934C (da) 1989-10-09
EP0080061A1 (fr) 1983-06-01
CA1202968A (fr) 1986-04-08
JPH0336821B2 (fr) 1991-06-03
HU187814B (en) 1986-02-28
AU556560B2 (en) 1986-11-06
YU42604B (en) 1988-10-31
US4510323A (en) 1985-04-09

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