ES8203092A1 - Procedimiento para la preparacion de nuevos derivados este- roide-espiro-oxatiazolidinos - Google Patents
Procedimiento para la preparacion de nuevos derivados este- roide-espiro-oxatiazolidinosInfo
- Publication number
- ES8203092A1 ES8203092A1 ES500306A ES500306A ES8203092A1 ES 8203092 A1 ES8203092 A1 ES 8203092A1 ES 500306 A ES500306 A ES 500306A ES 500306 A ES500306 A ES 500306A ES 8203092 A1 ES8203092 A1 ES 8203092A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- image
- alkyl
- spiro
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS ESTEORIDE-ESPIRO-OXATIA-ZOLIDINOS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 ES UN GRUPO ALQUILO C1-3 O ALQUENILO C2-4 Y Z PUEDE SER UNO DE VARIOS RADICALES BIVALENTES DERIVADOS DE ESTEROIDES. CONSISTE EN LA REACCION DE CICLACION DE UN COMPUESTO DE FORMULA (II), EN LA QUE R1 Y Z TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN COMPUESTO DE FORMULA (III), EN LA QUE X ES HALOGENO O UN GRUPO 1-IMIDAZOLILO O LOS DOS GRUPOS X FORMAN UN GRUPO DE FORMULA = N-COOR5, SIENDO R5 UN ALQUILO C1-3. LA REACCION DE CICLACION SE LLEVA A CABO EN CONDICIONES QUE DEPENDEN DE LOS PRODUCTOS DE PARTIDA UTILIZADOS. EL GRUPO HIDROXILO EN POSICION 3 DEL COMPUESTO OBTENIDO SE PUEDE ALQUILAR, ACILAR U OXIDAR EN UN GRUPO CETO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU8080579A HU181066B (en) | 1980-03-12 | 1980-03-12 | Process for preparing steroid -spiro-oxathiazolidine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES500306A0 ES500306A0 (es) | 1982-02-01 |
ES8203092A1 true ES8203092A1 (es) | 1982-02-01 |
Family
ID=10950243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES500306A Expired ES8203092A1 (es) | 1980-03-12 | 1981-03-12 | Procedimiento para la preparacion de nuevos derivados este- roide-espiro-oxatiazolidinos |
Country Status (19)
Country | Link |
---|---|
US (1) | US4342754A (es) |
JP (1) | JPS56142300A (es) |
AT (1) | ATA111481A (es) |
AU (1) | AU6826781A (es) |
BE (1) | BE887833A (es) |
DE (1) | DE3109523A1 (es) |
DK (1) | DK111581A (es) |
ES (1) | ES8203092A1 (es) |
FI (1) | FI810761L (es) |
FR (1) | FR2478106A1 (es) |
GB (1) | GB2073201B (es) |
HU (1) | HU181066B (es) |
IL (1) | IL62347A0 (es) |
IT (1) | IT1142000B (es) |
NL (1) | NL8101188A (es) |
NO (1) | NO810838L (es) |
NZ (1) | NZ196464A (es) |
SE (1) | SE8101516L (es) |
SU (1) | SU1079177A3 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
US4772406A (en) * | 1987-04-08 | 1988-09-20 | Exxon Chemical Patents Inc. | Olefinic hydrocarbon modification with sulfur imides |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU179711B (en) * | 1977-03-14 | 1982-11-29 | Gyogyszerkutato Intezet | Process for preparing steroid-spiro-oxazolidinone derivatives |
HU178397B (en) * | 1978-04-01 | 1982-04-28 | Gyogyszerkutato Intezet | Process for preparing substituted derivatives of steroid-spiro-oxazolidione derivatives |
US4239757A (en) * | 1979-07-24 | 1980-12-16 | Interx Research Corporation | Thiazolidine prodrugs for the improved delivery of anti-inflammatory corticosteroids |
-
1980
- 1980-03-12 HU HU8080579A patent/HU181066B/hu unknown
-
1981
- 1981-03-09 BE BE1/10162A patent/BE887833A/fr not_active IP Right Cessation
- 1981-03-10 SE SE8101516A patent/SE8101516L/xx not_active Application Discontinuation
- 1981-03-11 FI FI810761A patent/FI810761L/fi not_active Application Discontinuation
- 1981-03-11 IL IL62347A patent/IL62347A0/xx unknown
- 1981-03-11 FR FR8104829A patent/FR2478106A1/fr active Granted
- 1981-03-11 DK DK111581A patent/DK111581A/da not_active Application Discontinuation
- 1981-03-11 US US06/242,711 patent/US4342754A/en not_active Expired - Fee Related
- 1981-03-11 IT IT20276/81A patent/IT1142000B/it active
- 1981-03-11 AT AT0111481A patent/ATA111481A/de not_active Application Discontinuation
- 1981-03-11 NO NO810838A patent/NO810838L/no unknown
- 1981-03-11 SU SU813260499A patent/SU1079177A3/ru active
- 1981-03-11 NL NL8101188A patent/NL8101188A/nl not_active Application Discontinuation
- 1981-03-11 AU AU68267/81A patent/AU6826781A/en not_active Abandoned
- 1981-03-11 NZ NZ196464A patent/NZ196464A/xx unknown
- 1981-03-11 GB GB8107596A patent/GB2073201B/en not_active Expired
- 1981-03-12 JP JP3469281A patent/JPS56142300A/ja active Pending
- 1981-03-12 ES ES500306A patent/ES8203092A1/es not_active Expired
- 1981-03-12 DE DE3109523A patent/DE3109523A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
NZ196464A (en) | 1982-12-07 |
IL62347A0 (en) | 1981-05-20 |
GB2073201B (en) | 1983-10-12 |
FR2478106A1 (fr) | 1981-09-18 |
GB2073201A (en) | 1981-10-14 |
HU181066B (en) | 1983-05-30 |
DK111581A (da) | 1981-09-13 |
BE887833A (fr) | 1981-09-09 |
FR2478106B1 (es) | 1983-11-10 |
SU1079177A3 (ru) | 1984-03-07 |
NO810838L (no) | 1981-09-14 |
ATA111481A (de) | 1983-12-15 |
US4342754A (en) | 1982-08-03 |
DE3109523A1 (de) | 1982-02-18 |
ES500306A0 (es) | 1982-02-01 |
NL8101188A (nl) | 1981-10-01 |
FI810761L (fi) | 1981-09-13 |
AU6826781A (en) | 1981-09-17 |
JPS56142300A (en) | 1981-11-06 |
SE8101516L (sv) | 1981-09-13 |
IT8120276A0 (it) | 1981-03-11 |
IT1142000B (it) | 1986-10-08 |
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