US3984396A
(en)
*
|
1971-06-01 |
1976-10-05 |
Icn Pharmaceuticals, Inc. |
1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters
|
DE2401449A1
(de)
*
|
1973-01-16 |
1974-07-25 |
Voorhees |
Pharmazeutische zusammensetzung zur linderung von hautproliferationserkrankungen
|
US3888843A
(en)
*
|
1973-06-12 |
1975-06-10 |
Toyo Jozo Kk |
4-carbamoyl-1-' -d-ribofuranosylimidazolium-5-olate
|
AR207138A1
(es)
*
|
1974-03-18 |
1976-09-15 |
Icn Pharmaceuticals |
Metodo para la obtencion de 1,2,4-triazoles n-substituidos y sus sales de adicion
|
GB1482736A
(en)
*
|
1974-03-18 |
1977-08-10 |
Icn Pharmaceuticals |
1-(beta-d-ribofuranosyl)-1,2,4-triazole acid derivatives
|
US3960836A
(en)
*
|
1974-07-22 |
1976-06-01 |
Eli Lilly And Company |
Acylated derivatives of pyrazofurin and process for their preparation
|
US4007198A
(en)
*
|
1975-05-01 |
1977-02-08 |
American Cyanamid Company |
Substituted 1,2,4-triazole carboxamide
|
US4138547A
(en)
*
|
1977-12-22 |
1979-02-06 |
Icn Pharmaceuticals, Inc. |
Process for preparing 1,2,4-triazole nucleosides
|
JPS57146593A
(en)
*
|
1981-03-09 |
1982-09-10 |
Ajinomoto Co Inc |
Preparation of ribofuranosyltriazole derivative
|
US4451648A
(en)
*
|
1981-08-19 |
1984-05-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Process for the production of 2-β-D-ribofuranosylthiazole-4-carboxamide
|
US4531001A
(en)
*
|
1982-03-23 |
1985-07-23 |
Brigham Young University |
2-β-D-ribofuranosylselenazole-4-carboxamide compounds
|
US4446315A
(en)
*
|
1982-09-24 |
1984-05-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adenosine 5'-triphosphate-4-carboxamide-ribofuranosylthiazole
|
JPS5964648U
(ja)
*
|
1982-10-22 |
1984-04-28 |
阿波野 政晴 |
日覆用骨格
|
BE902199A
(fr)
*
|
1984-10-29 |
1985-07-31 |
Vira Tek Inc |
Procede de traitement medical de maladies virales utilisant le 1-beta-d-ribofurannosyl-1, 2,4-triazole-3-carboxamide.
|
NZ213370A
(en)
*
|
1985-01-16 |
1989-03-29 |
Vira Tek Inc |
Method of treating viral infections of selected trees and field crops using ribavirin (1-b-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) or the 2,3,5-triacetyl or 5'-butyryl derivative thereof
|
DE3606634A1
(de)
*
|
1986-02-28 |
1987-09-03 |
Mack Chem Pharm |
Isohexid-nucleoside, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
WO1987005807A1
(fr)
*
|
1986-03-27 |
1987-10-08 |
Harry Edward Gruber |
Procede pour augmenter l'excretion d'adenosine
|
US4925930A
(en)
*
|
1988-11-02 |
1990-05-15 |
Nucleic Acid Research Institute |
Synthesis and anti-leukemic activity of alkyl-1-(β-D-ribofuranosyl)[1,2,4]triazole-3-carboximidates
|
US5438131A
(en)
*
|
1992-09-16 |
1995-08-01 |
Bergstrom; Donald E. |
3-nitropyrrole nucleoside
|
EP1244356A4
(fr)
*
|
1999-12-23 |
2003-03-19 |
Icn Pharmaceuticals |
Compositions et procedes relatives a des nucleosides-l, a des nucleotides-l ainsi qu'a leurs analogues
|
US6455508B1
(en)
*
|
2000-02-15 |
2002-09-24 |
Kanda S. Ramasamy |
Methods for treating diseases with tirazole and pyrrolo-pyrimidine ribofuranosyl nucleosides
|
US6495677B1
(en)
*
|
2000-02-15 |
2002-12-17 |
Kanda S. Ramasamy |
Nucleoside compounds
|
US7638496B2
(en)
*
|
2000-02-15 |
2009-12-29 |
Valeant Pharmaceuticals North America |
Nucleoside analogs with carboxamidine modified monocyclic base
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
NZ547204A
(en)
|
2000-05-26 |
2008-01-31 |
Idenix Cayman Ltd |
Methods and compositions for treating flaviviruses and pestiviruses
|
US6815542B2
(en)
*
|
2000-06-16 |
2004-11-09 |
Ribapharm, Inc. |
Nucleoside compounds and uses thereof
|
IL154168A0
(en)
*
|
2000-08-22 |
2003-07-31 |
Ribapharm Inc |
Improved specificity in treatment of diseases
|
WO2002044717A1
(fr)
*
|
2000-12-01 |
2002-06-06 |
Cornell Research Foundation |
Modele animal d'infection par virus des flaviviridae
|
US20040014696A1
(en)
*
|
2000-12-07 |
2004-01-22 |
Johnson Lau |
Specificity in treatment of diseases
|
US6720000B2
(en)
*
|
2001-03-19 |
2004-04-13 |
Three Rivers Pharmaceutical, Llc |
Process for producing wet ribavirin pellets
|
ATE252594T1
(de)
*
|
2001-07-30 |
2003-11-15 |
Clariant Lsm Italia Spa |
Verfahren zur herstellung von ribavirin
|
AU2002330154A1
(en)
*
|
2001-09-28 |
2003-04-07 |
Centre National De La Recherche Scientifique |
Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
|
WO2003039517A1
(fr)
*
|
2001-11-02 |
2003-05-15 |
Sandoz Inc. |
Procede de preparation de compositions de ribavirine a charge elevee et a dissolution rapide
|
KR100411398B1
(ko)
|
2001-12-06 |
2003-12-18 |
주식회사유한양행 |
베타-디-리보푸라노즈 유도체의 제조방법
|
US7608600B2
(en)
*
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
AU2003248748A1
(en)
*
|
2002-06-28 |
2004-01-19 |
Idenix (Cayman) Limited |
2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
NZ537662A
(en)
*
|
2002-06-28 |
2007-10-26 |
Idenix Cayman Ltd |
2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
|
WO2004002999A2
(fr)
|
2002-06-28 |
2004-01-08 |
Idenix (Cayman) Limited |
Promedicaments a nucleosides 2' et 3' destines a traiter les infections aux flavivirus
|
US20040067877A1
(en)
*
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
US7538094B2
(en)
*
|
2002-09-19 |
2009-05-26 |
Three Rivers Pharmacueticals, Llc |
Composition containing ribavirin and use thereof
|
KR20050088079A
(ko)
*
|
2002-11-15 |
2005-09-01 |
이데닉스 (케이만) 리미티드 |
2'-분지형 뉴클레오시드 및 플라비비리다에 돌연변이
|
CA2509687C
(fr)
*
|
2002-12-12 |
2012-08-14 |
Idenix (Cayman) Limited |
Procede de production de nucleosides ramifies en position 2'
|
RU2005123395A
(ru)
*
|
2002-12-23 |
2006-01-27 |
Айденикс (Кайман) Лимитед (Ky) |
Способ получения 3-нуклеозидных пролекарств
|
JP2006524227A
(ja)
*
|
2003-03-28 |
2006-10-26 |
ファーマセット,インク. |
フラビウイルス科ウイルス感染の治療のための化合物
|
CA2734052A1
(fr)
|
2003-05-30 |
2005-01-13 |
Pharmasset, Inc. |
Analogues de nucleosides fluores modifies
|
PL1658302T3
(pl)
|
2003-07-25 |
2011-03-31 |
Idenix Pharmaceuticals Inc |
Analogi nukleozydów purynowych do leczenia chorób spowodowanych przez Flaviviridae obejmujących zapalenie wątroby typu C
|
WO2005018330A1
(fr)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Regime de dosage pour therapie contre flaviviridae
|
US20050187192A1
(en)
*
|
2004-02-20 |
2005-08-25 |
Kucera Pharmaceutical Company |
Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
|
CA2571675A1
(fr)
*
|
2004-06-23 |
2006-01-05 |
Idenix (Cayman) Limited |
Derives de 5-aza-7-deazapurine pour le traitement des infections avec flaviviridae
|
CN101023094B
(zh)
*
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
RU2433124C2
(ru)
*
|
2004-09-14 |
2011-11-10 |
Фармассет, Инк. |
Способ получения 2'-фтор-2'-алкилзамещенных или других замещенных рибофуранозилпиримидинов и пуринов и их производных
|
BRPI0613962A2
(pt)
|
2005-07-25 |
2009-03-24 |
Intermune Inc |
inibidores macrocìclicos inovadores de replicação de vìrus da hepatite c
|
GEP20104956B
(en)
*
|
2005-10-11 |
2010-04-12 |
Array Biopharma Inc |
Compounds for inhibiting hepatitis c viral replication and use thereof
|
JP5254033B2
(ja)
*
|
2005-12-23 |
2013-08-07 |
イデニク プハルマセウティカルス,インコーポレイテッド |
分岐型ヌクレオシドを調製するための合成中間体の製造方法
|
CA2643680A1
(fr)
|
2006-04-11 |
2007-11-22 |
Novartis Ag |
Composes organiques et leurs utilisations
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
WO2009028575A1
(fr)
|
2007-08-27 |
2009-03-05 |
National University Corporation Nagoya University |
Activateur pour le promoteur du facteur vii de la coagulation du sang et son utilisation
|
JPWO2009028573A1
(ja)
|
2007-08-27 |
2010-12-09 |
国立大学法人名古屋大学 |
血液凝固障害におけるリバビリンの利用
|
US20090082414A1
(en)
*
|
2007-09-26 |
2009-03-26 |
Protia, Llc |
Deuterium-enriched viramidine
|
WO2009105258A1
(fr)
|
2008-02-22 |
2009-08-27 |
Nektar Therapeutics Al, Corporation |
Conjugués oligomères de nucléosides hétéropentacycliques
|
TW200946541A
(en)
*
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
AP2010005416A0
(en)
*
|
2008-04-15 |
2010-10-31 |
Intermune Inc |
Novel macrocyclic inhibitors of hepatitis c virus replication.
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
CN102216321A
(zh)
*
|
2008-10-15 |
2011-10-12 |
因特蒙公司 |
治疗性抗病毒肽
|
AU2009333559B2
(en)
|
2008-12-09 |
2015-03-12 |
Gilead Sciences, Inc. |
Modulators of toll-like receptors
|
EA201100851A1
(ru)
*
|
2008-12-23 |
2012-04-30 |
Фармассет, Инк. |
Аналоги нуклеозидов
|
CL2009002206A1
(es)
*
|
2008-12-23 |
2011-08-26 |
Gilead Pharmasset Llc |
Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
|
NZ593648A
(en)
*
|
2008-12-23 |
2013-09-27 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
CN102741270B
(zh)
*
|
2009-09-28 |
2015-07-22 |
英特穆恩公司 |
C型肝炎病毒复制的环肽抑制剂
|
TW201116540A
(en)
*
|
2009-10-01 |
2011-05-16 |
Intermune Inc |
Therapeutic antiviral peptides
|
WO2011076923A1
(fr)
|
2009-12-23 |
2011-06-30 |
Institut National De La Sante Et De La Recherche Medicale |
Inhibiteur de l'inosine monophosphate (imp) déshydrogénase et/ou de l'arn polymérase viral utile(s) pour le traitement de l'hépatite e
|
US8785487B2
(en)
*
|
2010-01-25 |
2014-07-22 |
Enanta Pharmaceuticals, Inc. |
Hepatitis C virus inhibitors
|
US8933110B2
(en)
|
2010-01-25 |
2015-01-13 |
Enanta Pharmaceuticals, Inc. |
Hepatitis C virus inhibitors
|
US8563530B2
(en)
|
2010-03-31 |
2013-10-22 |
Gilead Pharmassel LLC |
Purine nucleoside phosphoramidate
|
BR112012024884A2
(pt)
|
2010-03-31 |
2016-10-18 |
Gilead Pharmasset Llc |
síntese estereosseletiva de ativos contendo fósforo
|
US9011833B2
(en)
|
2010-10-08 |
2015-04-21 |
Novartis Ag |
Vitamin E formulations of sulfamide NS3 inhibitors
|
AR084044A1
(es)
|
2010-11-30 |
2013-04-17 |
Pharmasset Inc |
Compuestos 2’-espiro-nucleosidos
|
TW201701876A
(zh)
|
2010-12-20 |
2017-01-16 |
吉李德科學股份有限公司 |
治療c型肝炎病毒(hcv)之方法
|
CA2752008A1
(fr)
|
2011-09-13 |
2013-03-13 |
Universite De Montreal |
Therapie combinee utilisant de la ribavirine a titre d'inhibiteur de l'elf4e
|
CN104244945B
(zh)
|
2011-09-16 |
2016-08-31 |
吉利德制药有限责任公司 |
用于治疗hcv的方法
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
AU2013340559B2
(en)
|
2012-10-29 |
2018-03-15 |
Cipla Limited |
Antiviral phosphonate analogues and process for preparation thereof
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
DK2950786T3
(da)
|
2013-01-31 |
2020-02-17 |
Gilead Pharmasset Llc |
Kombinationsformulering af to antivirale forbindelser
|
ES2792503T3
(es)
|
2013-08-27 |
2020-11-11 |
Gilead Pharmasset Llc |
Formulación combinada de dos compuestos antivirales
|
EA201692507A1
(ru)
|
2014-06-23 |
2017-04-28 |
Сановель Илач Санайи Ве Тиджарет А.Ш. |
Фармацевтические комбинации софосбувира и рибавирина
|
WO2015197549A1
(fr)
|
2014-06-23 |
2015-12-30 |
Sanovel Ilac Sanayi Ve Ticaret A.S. |
Nouvelle composition pharmaceutique de sofosbuvir et de ribavirine
|
US20170128482A1
(en)
|
2014-06-23 |
2017-05-11 |
Sanovel Ilac Sanayi Ve Ticaret A.S. |
Modified release pharmaceutical compositions of sofosbuvir and ribavirin
|
TWI733652B
(zh)
|
2014-07-11 |
2021-07-21 |
美商基利科學股份有限公司 |
用於治療HIV之toll樣受體調節劑
|
EP3194401B1
(fr)
|
2014-09-16 |
2020-10-21 |
Gilead Sciences, Inc. |
Formes solides d'un modulateur de récepteur de type toll
|
TW201817714A
(zh)
|
2016-08-30 |
2018-05-16 |
英商葛蘭素史密斯克藍智慧財產權有限公司 |
抑制3c及3cl蛋白酶之化合物及其使用方法
|
CN110713464B
(zh)
*
|
2019-10-31 |
2023-03-31 |
重庆大学 |
一种芳基1,2,4-三氮唑核苷化合物及其制备方法和应用
|
US20230218644A1
(en)
|
2020-04-16 |
2023-07-13 |
Som Innovation Biotech, S.A. |
Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
|