MY192062A - Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof - Google Patents

Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof

Info

Publication number
MY192062A
MY192062A MYPI2017000852A MYPI2017000852A MY192062A MY 192062 A MY192062 A MY 192062A MY PI2017000852 A MYPI2017000852 A MY PI2017000852A MY PI2017000852 A MYPI2017000852 A MY PI2017000852A MY 192062 A MY192062 A MY 192062A
Authority
MY
Malaysia
Prior art keywords
receptor
chimeric antigen
antigen receptors
fcrl5
cars
Prior art date
Application number
MYPI2017000852A
Other languages
English (en)
Inventor
Eric L Smith
Cheng Liu
Renier J Brentjens
Original Assignee
Memorial Sloan Kettering Cancer Center
Eureka Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Memorial Sloan Kettering Cancer Center, Eureka Therapeutics Inc filed Critical Memorial Sloan Kettering Cancer Center
Publication of MY192062A publication Critical patent/MY192062A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
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    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2319/00—Fusion polypeptide
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
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MYPI2017000852A 2014-12-05 2015-12-04 Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof MY192062A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462088164P 2014-12-05 2014-12-05
PCT/US2015/064134 WO2016090337A1 (en) 2014-12-05 2015-12-04 Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof

Publications (1)

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MY192062A true MY192062A (en) 2022-07-25

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US (3) US11059891B2 (OSRAM)
EP (2) EP3227436B1 (OSRAM)
JP (3) JP7174522B2 (OSRAM)
KR (1) KR20170108946A (OSRAM)
CN (2) CN116063565A (OSRAM)
AU (2) AU2015357543B2 (OSRAM)
BR (1) BR112017011936A8 (OSRAM)
IL (2) IL252655B (OSRAM)
MX (1) MX395028B (OSRAM)
MY (1) MY192062A (OSRAM)
NZ (1) NZ732570A (OSRAM)
PH (1) PH12017501041A1 (OSRAM)
SG (2) SG10202008076RA (OSRAM)
WO (1) WO2016090337A1 (OSRAM)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016090337A1 (en) 2014-12-05 2016-06-09 Memorial Sloan-Kettering Cancer Center Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof
WO2016210129A1 (en) * 2015-06-23 2016-12-29 Memorial Sloan-Kettering Cancer Center Novel pd-1 immune modulating agents
CN109071654B (zh) 2015-12-04 2022-09-23 纪念斯隆-凯特琳癌症中心 靶向Fc受体样5的抗体及使用方法
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