MY131641A - Indoline derivatives, process of preparation and use - Google Patents
Indoline derivatives, process of preparation and useInfo
- Publication number
- MY131641A MY131641A MYPI94003410A MYPI9403410A MY131641A MY 131641 A MY131641 A MY 131641A MY PI94003410 A MYPI94003410 A MY PI94003410A MY PI9403410 A MYPI9403410 A MY PI9403410A MY 131641 A MY131641 A MY 131641A
- Authority
- MY
- Malaysia
- Prior art keywords
- formula
- preparation
- indoline derivatives
- 6alkyl
- integer
- Prior art date
Links
- 125000003387 indolinyl group Chemical class N1(CCC2=CC=CC=C12)* 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 abstract 1
- 229960003987 melatonin Drugs 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939326192A GB9326192D0 (en) | 1993-12-22 | 1993-12-22 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY131641A true MY131641A (en) | 2007-08-30 |
Family
ID=10747030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI94003410A MY131641A (en) | 1993-12-22 | 1994-12-19 | Indoline derivatives, process of preparation and use |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5633276A (enExample) |
| EP (1) | EP0736028A1 (enExample) |
| JP (1) | JPH09507057A (enExample) |
| AP (1) | AP535A (enExample) |
| AU (1) | AU684877B2 (enExample) |
| CA (1) | CA2179402A1 (enExample) |
| CO (1) | CO4340623A1 (enExample) |
| GB (1) | GB9326192D0 (enExample) |
| IL (1) | IL112097A (enExample) |
| IS (1) | IS4244A (enExample) |
| MY (1) | MY131641A (enExample) |
| SV (1) | SV1994000083A (enExample) |
| TW (1) | TW291479B (enExample) |
| WO (1) | WO1995017405A1 (enExample) |
| ZA (1) | ZA9410056B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2741799B1 (fr) * | 1995-12-04 | 1998-01-02 | Oreal | Utilisation de melatonine dans une composition pour traiter les signes cutanes des etats de fatigue |
| US6034239A (en) * | 1996-03-08 | 2000-03-07 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| WO1997032871A1 (en) * | 1996-03-08 | 1997-09-12 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
| EP1199304A1 (en) * | 1997-03-05 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders |
| KR100499106B1 (ko) * | 1996-12-10 | 2005-07-01 | 브리스톨-마이어즈 스퀴브 컴페니 | 벤조디옥솔, 벤조퓨란, 디히드로벤조퓨란, 및 벤조디옥산 멜라토닌 작용제 |
| US5948817A (en) * | 1997-03-05 | 1999-09-07 | Bristol-Myers Squibb Company | Polycyclic ethyl alkylamide melatonergic agents |
| FR2763335B1 (fr) * | 1997-05-16 | 2000-11-24 | Adir | Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| AU727654B2 (en) * | 1997-06-13 | 2000-12-21 | Yamanouchi Pharmaceutical Co., Ltd. | Tricyclic pyrazole derivative |
| CA2334299A1 (en) | 1998-06-05 | 1999-12-09 | Pierre Dextraze | Heterocyclic cis cyclopropane derivatives as melatonergic agents |
| PT1189900E (pt) | 1999-06-30 | 2004-05-31 | Bristol Myers Squibb Co | Derivados de aminopirrolidina heterociclicos utilizados como agentes melatonergicos |
| GB9918965D0 (en) | 1999-08-11 | 1999-10-13 | Cerebrus Ltd | Chemical compounds xxi |
| AU6595000A (en) | 1999-08-20 | 2001-03-19 | Takeda Chemical Industries Ltd. | Dihydrobenzofuran derivatives, process for the preparation thereof and agents |
| US7012090B1 (en) | 2000-03-17 | 2006-03-14 | Alcon, Inc. | Pyranoindoles for treating glaucoma |
| DE60005566T2 (de) * | 2000-03-17 | 2004-07-29 | Alcon, Inc. | Pyranoindole zur glaukombehandlung |
| ES2172415B2 (es) | 2000-07-28 | 2003-11-16 | Univ Madrid Complutense | Tratamiento del glaucoma y la hipertension ocular por medio de un analogo de la melatonina. |
| US6743448B2 (en) * | 2000-12-11 | 2004-06-01 | Abraham H. Kryger | Topical testosterone formulations and associated methods |
| US20030096379A1 (en) * | 2001-03-28 | 2003-05-22 | Kilgore James L. | Method for producing tryptamine derivatives |
| AR059935A1 (es) * | 2006-03-20 | 2008-05-07 | Takeda Pharmaceutical | Composicion farmaceutica para la prevencion o tratamiento del sindrome de colon irritable |
| CN101605795A (zh) | 2006-12-08 | 2009-12-16 | 武田药品工业株式会社 | 三环化合物及其药物用途 |
| ES2331274B1 (es) * | 2007-10-25 | 2010-10-21 | Ferrer Internacional, S.A. | Compuesto de indolina. |
| BRPI0916395A2 (pt) | 2008-07-30 | 2016-02-16 | Ferrer Int | compostos de 1,6-di-hidro-2h-3-oxa-6-aza-as-indaceno |
| BR102016024814A2 (pt) | 2016-10-24 | 2018-05-08 | Aché Laboratórios Farmacêuticos S.A. | composto, processo de obtenção do composto, composição farmacêutica, uso do composto e método de tratamento de desordens psiquiátricas e/ou distúrbios do sono |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2485539A1 (fr) * | 1980-06-26 | 1981-12-31 | Sori Soc Rech Ind | Nouveau derive de pyranno-indole, son procede de preparation et son application en therapeutique |
| US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
| WO1986007056A1 (en) * | 1985-05-21 | 1986-12-04 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
-
1993
- 1993-12-22 GB GB939326192A patent/GB9326192D0/en active Pending
-
1994
- 1994-12-08 TW TW083111439A patent/TW291479B/zh active
- 1994-12-16 IS IS4244A patent/IS4244A/is unknown
- 1994-12-19 MY MYPI94003410A patent/MY131641A/en unknown
- 1994-12-19 ZA ZA9410056A patent/ZA9410056B/xx unknown
- 1994-12-20 JP JP7517174A patent/JPH09507057A/ja active Pending
- 1994-12-20 AU AU12743/95A patent/AU684877B2/en not_active Ceased
- 1994-12-20 US US08/652,460 patent/US5633276A/en not_active Expired - Fee Related
- 1994-12-20 AP APAP/P/1994/000706A patent/AP535A/en active
- 1994-12-20 EP EP95903817A patent/EP0736028A1/en not_active Ceased
- 1994-12-20 CA CA002179402A patent/CA2179402A1/en not_active Abandoned
- 1994-12-20 WO PCT/EP1994/004220 patent/WO1995017405A1/en not_active Ceased
- 1994-12-21 IL IL112097A patent/IL112097A/en not_active IP Right Cessation
- 1994-12-21 SV SV1994000083A patent/SV1994000083A/es unknown
- 1994-12-21 CO CO94057739A patent/CO4340623A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5633276A (en) | 1997-05-27 |
| IL112097A0 (en) | 1995-03-15 |
| IL112097A (en) | 1998-06-15 |
| CO4340623A1 (es) | 1996-07-30 |
| SV1994000083A (es) | 1995-07-24 |
| ZA9410056B (en) | 1995-10-18 |
| JPH09507057A (ja) | 1997-07-15 |
| AU1274395A (en) | 1995-07-10 |
| TW291479B (enExample) | 1996-11-21 |
| EP0736028A1 (en) | 1996-10-09 |
| AU684877B2 (en) | 1998-01-08 |
| IS4244A (is) | 1995-06-23 |
| WO1995017405A1 (en) | 1995-06-29 |
| AP535A (en) | 1996-09-16 |
| CA2179402A1 (en) | 1995-06-29 |
| GB9326192D0 (en) | 1994-02-23 |
| AP9400706A0 (en) | 1995-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW347387B (en) | Piperidine derivatives | |
| BG102600A (en) | Carbamoyloxy derivatives of mutilin and their use as bactericides | |
| MY108885A (en) | Heterocyclic-cyclic amine derivatives. | |
| ES8700234A1 (es) | Un procedimiento para la preparacion de derivados del indol. | |
| GR3033020T3 (en) | Amide and urea derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses. | |
| NO996108L (no) | 9-oksinerytromycinderivater | |
| MY117092A (en) | Chemotherapeutic pyrrolocarbazole derivatives | |
| MY113266A (en) | New indol derivatives derivatives with high affinity 5-ht1a receptor. | |
| CO4340623A1 (es) | Derivados de indolina, metodo de preparacion y uso | |
| DE69227088D1 (de) | Verwendung von 1-(aminoalkyl)-3-Quinoxalin-2-on Derivaten zur Herstellung von neuroprotektiven Mitteln | |
| SE8505887L (sv) | Indoler | |
| IE890177L (en) | Piperidinyl derivatives | |
| ES8401067A1 (es) | Procedimiento analogo para preparar un derivado de tropil benzoato. | |
| TW333532B (en) | Benzopyrans | |
| TW328957B (en) | Substituted benzothienylpiperazines, their use as medicaments, and processes for their preparation | |
| UA41880C2 (uk) | Серотонінергічні похідні ерголіну і фармацевтична композиція | |
| ES2102327A1 (es) | Nuevos derivados de 2,2,6,6-tetrametilpiperidina para utilizarse como agentes estabilizantes para materiales organicos contra la luz, el calor, y la oxidacion. n | |
| NO994104L (no) | 5-hydroksymetyl-2-aminotetraliner i form av kardiovaskulaere midler | |
| BG103271A (en) | Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means | |
| NO934741L (no) | Fremgangsmåte for minimalisering og kontroll av ischemiske og reperfusjonsskade | |
| AU3386299A (en) | N-aryloxyethylamine derivatives for the treatment of depression | |
| TW349864B (en) | Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders | |
| ES8506032A1 (es) | Un procedimiento para la preparacion de un derivado de ergolina | |
| EP0466662A3 (en) | 6,7-disubstituted-2-aminotetralines active as immunomodulators and pharmaceutical compositions containing same | |
| NO950731L (no) | Optisk aktive karboksamidderivater |