MXPA96004705A - Metodo para detectar la presencia de una especie de microbacteria y un juego de implementos y anticuerpos para su uso en ese aspecto. - Google Patents
Metodo para detectar la presencia de una especie de microbacteria y un juego de implementos y anticuerpos para su uso en ese aspecto.Info
- Publication number
- MXPA96004705A MXPA96004705A MXPA96004705A MX9604705A MXPA96004705A MX PA96004705 A MXPA96004705 A MX PA96004705A MX PA96004705 A MXPA96004705 A MX PA96004705A MX 9604705 A MX9604705 A MX 9604705A MX PA96004705 A MXPA96004705 A MX PA96004705A
- Authority
- MX
- Mexico
- Prior art keywords
- antigens
- mycobacterium
- test
- detection
- kit
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1289—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Mycobacteriaceae (F)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
Abstract
La invencion se refiere a una prueba de diagnostico para detectar e identificar la especie Mycobacterium en muestras biologicas de origen humano y animal. La prueba se basan en la deteccion inmunologica de uno o varios antigenos que se originan a partir de Mycobacterium. Para permitir la deteccion de una reaccion anticuerpo-antigeno, los anticuerpos especificos para estos antigenos pueden estar marcados con una enzima o un tinte fluorescente o bien fijados con particulas de latex o bien por medio de cualquier otro marcador adecuado. La prueba de diagnostico puede realizarse en forma de ELISA y puede o no requerir de concentracion de antigenos de Mycobacterium antes de la prueba real. La invencion comprende: la seleccion y obtencion de una especie y sepa microbacteriana adecuada, el aislamiento y la purificacion de los antigenos, la preparacion de los conjugados necesarios para la inmunizacion de los animales de experimento usando varias moleculas portadoras, el desarrollo de un ensayo para monitorear la produccion de anticuerpos, la caracterizacion de los anticuerpos especificos para el antigeno/antigenos de Mycobacterium y el desarrollo de un ensayo/conjunto de implementos para el diagnostico.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA942575 | 1994-04-14 | ||
| ZA951464 | 1995-02-22 | ||
| PCT/GB1995/000856 WO1995028642A1 (en) | 1994-04-14 | 1995-04-13 | A method for detecting the presence of a mycobacterium species and a kit and antibodies for use therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA96004705A true MXPA96004705A (es) | 2004-08-19 |
Family
ID=27142386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA96004705A MXPA96004705A (es) | 1994-04-14 | 1995-04-13 | Metodo para detectar la presencia de una especie de microbacteria y un juego de implementos y anticuerpos para su uso en ese aspecto. |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6124105A (es) |
| EP (1) | EP0755517B1 (es) |
| JP (1) | JPH09512101A (es) |
| CN (1) | CN1150840A (es) |
| AT (1) | ATE187251T1 (es) |
| BR (1) | BR9507389A (es) |
| CA (1) | CA2187779A1 (es) |
| DE (1) | DE69513649T2 (es) |
| DK (1) | DK0755517T3 (es) |
| ES (1) | ES2141348T3 (es) |
| GR (1) | GR3032471T3 (es) |
| MX (1) | MXPA96004705A (es) |
| NZ (1) | NZ283784A (es) |
| PL (1) | PL181579B1 (es) |
| PT (1) | PT755517E (es) |
| WO (1) | WO1995028642A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0811075B1 (en) * | 1995-02-22 | 2008-05-14 | Adcock Ingram Limited | A method for the isolation and purification of lipid cell-wall components |
| US6015681A (en) * | 1995-07-28 | 2000-01-18 | The United States Of America As Represented By The Secretary Of The Navy | Rapid immunoassay for cariogenic bacteria |
| US6599691B1 (en) * | 1995-11-27 | 2003-07-29 | The United States Of America As Represented By The Secretary Of The Navy | Rapid immunoassay to detect infection with Mycobacterium tuberculosis |
| AU6631298A (en) | 1997-03-03 | 1998-09-22 | Adcock Ingram Limited | A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease |
| RS20050300A (en) | 2002-10-16 | 2007-08-03 | Euro-Celtique S.A., | Antibodies that bind cell-associated ca 125/0772p and methods of use thereof |
| ATE408837T1 (de) * | 2004-05-13 | 2008-10-15 | Univ Pretoria | Verfahren zum nachweis von infektionen mit mykobakterien |
| DE102004024674A1 (de) * | 2004-05-18 | 2005-12-15 | Wolfgang Lorenz | Mittel und Verfahren zur Diagnose, Prophylaxe und Therapie von Bindegewebserkrankungen |
| EP2593793B1 (en) * | 2010-07-15 | 2016-05-25 | University of Pretoria | A method of detecting surrogate markers for active tuberculosis in a serum sample |
| WO2012102679A1 (en) | 2011-01-24 | 2012-08-02 | National University Of Singapore | Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins |
| EP2629095A1 (en) * | 2012-02-17 | 2013-08-21 | Biosure R & T Cell Co. | Detection of mycobacterial protein targets using quantum dots (QDs) and immunomagnetic seperation |
| EP2997371B1 (en) | 2013-05-16 | 2018-11-07 | University of Pretoria | A method of diagnosing tuberculosis |
| CN104897894A (zh) * | 2015-06-15 | 2015-09-09 | 长春理工大学 | 一种检测胞内分枝杆菌的elisa检测方法 |
| CN105651996A (zh) * | 2016-02-29 | 2016-06-08 | 丹娜（天津）生物科技有限公司 | 一种新型隐球菌荚膜多糖抗原免疫检测试剂盒及其制备方法与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL71683A0 (en) * | 1984-04-27 | 1984-09-30 | Yeda Res & Dev | Pharmaceutical compositions for treating arthritis type diseases comprising fractions obtained from mycobacteria |
| US5591632A (en) * | 1987-03-02 | 1997-01-07 | Beth Israel Hospital | Recombinant BCG |
| DE68924265T2 (de) * | 1989-01-18 | 1996-02-15 | Sawai Seiyaku Kk | Verwendung von einem reagens zum nachweis eines mit einem säurebeständigen bakterienantigen übereinstimmenden antikörpers. |
| DE69433115T2 (de) * | 1993-06-21 | 2004-04-01 | Brigham And Women's Hospital, Boston | Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien |
| WO1996012190A2 (en) * | 1994-10-13 | 1996-04-25 | Brigham & Women's Hospital | Presentation of hydrophobic antigens to t-cells by cd1 molecules |
-
1995
- 1995-04-13 DK DK95915263T patent/DK0755517T3/da active
- 1995-04-13 CA CA002187779A patent/CA2187779A1/en not_active Abandoned
- 1995-04-13 DE DE69513649T patent/DE69513649T2/de not_active Expired - Fee Related
- 1995-04-13 ES ES95915263T patent/ES2141348T3/es not_active Expired - Lifetime
- 1995-04-13 PL PL95316792A patent/PL181579B1/pl unknown
- 1995-04-13 CN CN95193609A patent/CN1150840A/zh active Pending
- 1995-04-13 BR BR9507389A patent/BR9507389A/pt not_active Application Discontinuation
- 1995-04-13 PT PT95915263T patent/PT755517E/pt unknown
- 1995-04-13 JP JP7526812A patent/JPH09512101A/ja active Pending
- 1995-04-13 NZ NZ283784A patent/NZ283784A/xx unknown
- 1995-04-13 AT AT95915263T patent/ATE187251T1/de not_active IP Right Cessation
- 1995-04-13 EP EP95915263A patent/EP0755517B1/en not_active Expired - Lifetime
- 1995-04-13 MX MXPA96004705A patent/MXPA96004705A/es unknown
- 1995-04-13 US US08/722,055 patent/US6124105A/en not_active Expired - Lifetime
- 1995-04-13 WO PCT/GB1995/000856 patent/WO1995028642A1/en active IP Right Grant
-
1999
- 1999-05-04 US US09/304,893 patent/US6458367B1/en not_active Expired - Lifetime
-
2000
- 2000-01-25 GR GR20000400165T patent/GR3032471T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK0755517T3 (da) | 2000-05-01 |
| AU2220595A (en) | 1995-11-10 |
| EP0755517B1 (en) | 1999-12-01 |
| CN1150840A (zh) | 1997-05-28 |
| JPH09512101A (ja) | 1997-12-02 |
| ES2141348T3 (es) | 2000-03-16 |
| NZ283784A (en) | 1998-08-26 |
| BR9507389A (pt) | 1997-09-16 |
| DE69513649D1 (de) | 2000-01-05 |
| GR3032471T3 (en) | 2000-05-31 |
| US6124105A (en) | 2000-09-26 |
| DE69513649T2 (de) | 2000-04-06 |
| CA2187779A1 (en) | 1995-10-26 |
| EP0755517A1 (en) | 1997-01-29 |
| WO1995028642A1 (en) | 1995-10-26 |
| US6458367B1 (en) | 2002-10-01 |
| PL316792A1 (en) | 1997-02-17 |
| ATE187251T1 (de) | 1999-12-15 |
| PL181579B1 (pl) | 2001-08-31 |
| AU695968B2 (en) | 1998-08-27 |
| PT755517E (pt) | 2000-05-31 |
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