MXPA06012935A - Formulaciones de solucion farmaceuticas que contienen 17-aag. - Google Patents
Formulaciones de solucion farmaceuticas que contienen 17-aag.Info
- Publication number
- MXPA06012935A MXPA06012935A MXPA06012935A MXPA06012935A MXPA06012935A MX PA06012935 A MXPA06012935 A MX PA06012935A MX PA06012935 A MXPA06012935 A MX PA06012935A MX PA06012935 A MXPA06012935 A MX PA06012935A MX PA06012935 A MXPA06012935 A MX PA06012935A
- Authority
- MX
- Mexico
- Prior art keywords
- volume
- component
- amount
- aag
- cremophor
- Prior art date
Links
- AYUNIORJHRXIBJ-TXHRRWQRSA-N tanespimycin Chemical compound N1C(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@@H](O)[C@@H](OC)C[C@H](C)CC2=C(NCC=C)C(=O)C=C1C2=O AYUNIORJHRXIBJ-TXHRRWQRSA-N 0.000 title claims abstract description 58
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 78
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 46
- 239000008389 polyethoxylated castor oil Substances 0.000 claims abstract description 44
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 29
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- 238000000034 method Methods 0.000 claims description 29
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- QUANRIQJNFHVEU-UHFFFAOYSA-N oxirane;propane-1,2,3-triol Chemical group C1CO1.OCC(O)CO QUANRIQJNFHVEU-UHFFFAOYSA-N 0.000 claims description 21
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- JRZJKWGQFNTSRN-UHFFFAOYSA-N Geldanamycin Natural products C1C(C)CC(OC)C(O)C(C)C=C(C)C(OC(N)=O)C(OC)CCC=C(C)C(=O)NC2=CC(=O)C(OC)=C1C2=O JRZJKWGQFNTSRN-UHFFFAOYSA-N 0.000 description 14
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- KUFRQPKVAWMTJO-QSTRRNJOSA-N 17-dmag Chemical compound N1C(=O)\C(C)=C/C=C\[C@@H](OC)[C@H](OC(N)=O)\C(C)=C/[C@@H](C)[C@@H](O)[C@H](OC)C[C@@H](C)CC2=C(NCCN(C)C)C(=O)C=C1C2=O KUFRQPKVAWMTJO-QSTRRNJOSA-N 0.000 description 4
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| PCT/US2005/016010 WO2005110398A2 (en) | 2004-05-11 | 2005-05-06 | Pharmaceutical solution formulations containing 17-aag |
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| US20090197852A9 (en) * | 2001-08-06 | 2009-08-06 | Johnson Robert G Jr | Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor |
| KR20070044805A (ko) | 2004-04-15 | 2007-04-30 | 키아스마, 인코포레이티드 | 생물학적 장벽 투과를 촉진시킬 수 있는 조성물 |
| BRPI0609861A2 (pt) * | 2005-04-29 | 2010-05-11 | Kosan Biosciences Inc | uso de 17-aag ou 17-ag ou um pró-fármaco de ambos em combinação com um inibidor de proteassoma na preparação de formulações farmacêuticas para tratar mieloma múltiplo |
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- 2005-05-06 WO PCT/US2005/016010 patent/WO2005110398A2/en not_active Ceased
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- 2005-05-06 BR BRPI0511036-0A patent/BRPI0511036A/pt not_active IP Right Cessation
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| AU2005244115A1 (en) | 2005-11-24 |
| RU2006143666A (ru) | 2008-06-20 |
| WO2005110398A2 (en) | 2005-11-24 |
| JP2007537258A (ja) | 2007-12-20 |
| WO2005110398A3 (en) | 2006-05-04 |
| US20050256097A1 (en) | 2005-11-17 |
| CA2565583A1 (en) | 2005-11-24 |
| IL178689A0 (en) | 2007-02-11 |
| BRPI0511036A (pt) | 2007-11-27 |
| RU2382643C2 (ru) | 2010-02-27 |
| EP1744743A2 (en) | 2007-01-24 |
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