RU2382643C2 - Фармацевтические композиции в виде раствора, содержащие 17-aag - Google Patents

Фармацевтические композиции в виде раствора, содержащие 17-aag Download PDF

Info

Publication number
RU2382643C2
RU2382643C2 RU2006143666/15A RU2006143666A RU2382643C2 RU 2382643 C2 RU2382643 C2 RU 2382643C2 RU 2006143666/15 A RU2006143666/15 A RU 2006143666/15A RU 2006143666 A RU2006143666 A RU 2006143666A RU 2382643 C2 RU2382643 C2 RU 2382643C2
Authority
RU
Russia
Prior art keywords
vol
component
amount
aag
propylene glycol
Prior art date
Application number
RU2006143666/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2006143666A (ru
Inventor
Цзиян ЧЖУН (US)
Цзиян ЧЖУН
Питер Дж. ЛИКАРИ (US)
Питер Дж. ЛИКАРИ
Original Assignee
Козан Байосайенсиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Козан Байосайенсиз, Инк. filed Critical Козан Байосайенсиз, Инк.
Publication of RU2006143666A publication Critical patent/RU2006143666A/ru
Application granted granted Critical
Publication of RU2382643C2 publication Critical patent/RU2382643C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2006143666/15A 2004-05-11 2005-05-06 Фармацевтические композиции в виде раствора, содержащие 17-aag RU2382643C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57021504P 2004-05-11 2004-05-11
US60/570,215 2004-05-11
US11/123,570 2005-05-05
US11/123,570 US20050256097A1 (en) 2004-05-11 2005-05-05 Pharmaceutical solution formulations containing 17-AAG

Publications (2)

Publication Number Publication Date
RU2006143666A RU2006143666A (ru) 2008-06-20
RU2382643C2 true RU2382643C2 (ru) 2010-02-27

Family

ID=35310196

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006143666/15A RU2382643C2 (ru) 2004-05-11 2005-05-06 Фармацевтические композиции в виде раствора, содержащие 17-aag

Country Status (10)

Country Link
US (1) US20050256097A1 (enExample)
EP (1) EP1744743A2 (enExample)
JP (1) JP2007537258A (enExample)
AU (1) AU2005244115A1 (enExample)
BR (1) BRPI0511036A (enExample)
CA (1) CA2565583A1 (enExample)
IL (1) IL178689A0 (enExample)
MX (1) MXPA06012935A (enExample)
RU (1) RU2382643C2 (enExample)
WO (1) WO2005110398A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529800C2 (ru) * 2010-03-18 2014-09-27 ИННОФАРМА, Инк. Стабильные составы бортезомиба

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090197852A9 (en) * 2001-08-06 2009-08-06 Johnson Robert G Jr Method of treating breast cancer using 17-AAG or 17-AG or a prodrug of either in combination with a HER2 inhibitor
CA2563533C (en) 2004-04-15 2013-10-01 Shmuel A. Ben-Sasson Compositions capable of facilitating penetration across a biological barrier
WO2006119032A1 (en) * 2005-04-29 2006-11-09 Kosan Biosciences Incorporated Method of treating multiple myeloma using 17-aag or 17-ag or a prodrug of either in combination with a proteasome inhibitor
KR20080000682A (ko) * 2005-04-29 2008-01-02 코산 바이오사이언시즈, 인코포레이티드 17-aag 또는 17-ag, 또는 이들의 프로드럭을 사용한다발성 골수종의 치료 방법
US7648976B2 (en) * 2005-11-23 2010-01-19 Bristol-Myers Squibb Company 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20090042847A1 (en) * 2005-11-23 2009-02-12 Kosan Biosciences Incorporated 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
US20070167422A1 (en) * 2006-01-18 2007-07-19 Yu Kwok S Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations
EP2073803B1 (en) 2006-10-12 2018-09-19 Astex Therapeutics Limited Pharmaceutical combinations
WO2008055386A1 (fr) * 2006-11-10 2008-05-15 Shenzhen Shengeryimei Biotech Co., Ltd. Composition pharmaceutique hydrosoluble pour injection de 17-allyl amino-17-déméthoxy geldanamycine (17-aag)
PE20081506A1 (es) * 2006-12-12 2008-12-09 Infinity Discovery Inc Formulaciones de ansamicina
JP2010516282A (ja) * 2007-01-26 2010-05-20 コーサン バイオサイエンシーズ, インコーポレイテッド 工学的生合成によるマクロラクタム
JP2010533180A (ja) * 2007-07-09 2010-10-21 グレン エス. クウォン, 治療剤
MX2010003774A (es) * 2007-10-08 2010-04-27 Fovea Pharmaceuticals Sa Formulaciones oftalmicas acuosas.
US20090258869A1 (en) * 2008-02-08 2009-10-15 The Regents Of The University Of California Methods and compounds for treatment or prevention of substance-related disorders
WO2010032140A2 (en) 2008-09-17 2010-03-25 Chiasma Inc. Pharmaceutical compositions and related methods of delivery
US8236329B2 (en) * 2009-09-25 2012-08-07 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
US8945627B2 (en) 2011-05-05 2015-02-03 Wisconsin Alumni Research Foundation Micelles for the solubilization of gossypol
US10682415B2 (en) 2013-07-22 2020-06-16 Wisconsin Alumni Research Foundation Thermogel formulation for combination drug delivery
WO2016094831A1 (en) * 2014-12-11 2016-06-16 University Of Utah Research Foundation Bi-functional allosteric protein-drug molecules for targeted therapy
FI3253401T3 (fi) 2015-02-03 2025-07-09 Amryt Endo Inc Akromegallian hoitaminen suun kautta annettavalla oktreotidilla
JP2018008922A (ja) * 2015-08-04 2018-01-18 わかもと製薬株式会社 ステロイド白内障の予防及び治療
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925776A (en) * 1997-12-24 1999-07-20 Schein Pharmacetical, Inc. Polyethoxylated castor oil, process of making the same and formulations thereof
WO2000037050A1 (en) * 1998-12-22 2000-06-29 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Water-insoluble drug delivery system
US6682758B1 (en) * 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US553153A (en) * 1896-01-14 Type-writing machine
US4261989A (en) * 1979-02-19 1981-04-14 Kaken Chemical Co. Ltd. Geldanamycin derivatives and antitumor drug
US6262022B1 (en) * 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
US5932556A (en) * 1995-09-17 1999-08-03 Tam; Robert C Methods and compositions for regulation of CD28 expression
ATE554750T1 (de) * 1997-03-05 2012-05-15 Sugen Inc Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen
US20030044434A1 (en) * 1997-07-29 2003-03-06 Ping Gao Self-emulsifying formulation for lipophilic compounds
US6121323A (en) * 1997-12-03 2000-09-19 3M Innovative Properties Company Bishydroxyureas
TW471968B (en) * 1999-08-25 2002-01-11 Committee On Chinese Medicine Solamargine pharmaceutical composition for killing cancer cells
US20020037855A1 (en) * 2000-05-05 2002-03-28 Fritz Stanislaus Stabilized medicament containing cysteinyl derivatives
ATE526019T1 (de) * 2000-07-28 2011-10-15 Sloan Kettering Inst Cancer Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen
NZ526169A (en) * 2000-10-31 2005-12-23 Boehringer Ingelheim Pharma Oral dosage self-emulsifying formulations of pyranone protease inhibitors
US7025992B2 (en) * 2001-02-14 2006-04-11 Gw Pharma Limited Pharmaceutical formulations
JP4213472B2 (ja) * 2001-03-30 2009-01-21 アメリカ合衆国 ゲルダナマイシン誘導体及びそれを用いる癌の治療方法
WO2002092076A1 (en) * 2001-05-16 2002-11-21 Cytovia, Inc. Substituted coumarins and quinolines as caspases activators
US6962944B2 (en) * 2001-07-31 2005-11-08 Arqule, Inc. Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same
US6872715B2 (en) * 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
US6653319B1 (en) * 2001-08-10 2003-11-25 University Of Kentucky Research Foundation Pharmaceutical formulation for poorly water soluble camptothecin analogues
US8071133B2 (en) * 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
PT1435910E (pt) * 2001-10-19 2009-09-07 Isotechnika Inc Novos pré-concentrados de microemulsão de análogos da ciclosporina
CA2471081A1 (en) * 2001-12-19 2003-07-03 Alza Corporation Formulation & dosage form for the controlled delivery of therapeutic agents
HUP0402451A3 (en) * 2001-12-19 2008-04-28 Alza Corp Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
US6803046B2 (en) * 2002-08-16 2004-10-12 Bracco International B.V. Sincalide formulations
US7649006B2 (en) * 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925776A (en) * 1997-12-24 1999-07-20 Schein Pharmacetical, Inc. Polyethoxylated castor oil, process of making the same and formulations thereof
WO2000037050A1 (en) * 1998-12-22 2000-06-29 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Water-insoluble drug delivery system
US6682758B1 (en) * 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529800C2 (ru) * 2010-03-18 2014-09-27 ИННОФАРМА, Инк. Стабильные составы бортезомиба

Also Published As

Publication number Publication date
EP1744743A2 (en) 2007-01-24
RU2006143666A (ru) 2008-06-20
JP2007537258A (ja) 2007-12-20
MXPA06012935A (es) 2007-01-26
IL178689A0 (en) 2007-02-11
WO2005110398A2 (en) 2005-11-24
BRPI0511036A (pt) 2007-11-27
US20050256097A1 (en) 2005-11-17
AU2005244115A1 (en) 2005-11-24
CA2565583A1 (en) 2005-11-24
WO2005110398A3 (en) 2006-05-04

Similar Documents

Publication Publication Date Title
RU2382643C2 (ru) Фармацевтические композиции в виде раствора, содержащие 17-aag
AU2002352105B2 (en) Platinum derivative pharmaceutical formulations
RU2620341C2 (ru) Стабилизированная композиция пеметрекседа
US20100203114A1 (en) Micelle encapsulation of therapeutic agents
EP3424505A1 (en) Preparation and composition for treatment of malignant tumors
KR20070091121A (ko) 엑티나시딘 및 디사카라이드를 포함하는 제제
WO2007053284A2 (en) Method of treating breast cancer using 17-aag or 17-ag or a prodrug of either in combination with a her2 inhibitor
JP2008531708A (ja) 17−アリルアミノ−17−デメトキシゲルダナマイシンを含有する医薬製剤
US20070167422A1 (en) Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin
ES2991018T3 (es) (N-(2-((2-bencilfenil)amino)-2-oxoetil)-L-naftamida) como agente terapéutico anticanceroso
CN100490800C (zh) 含17-aag的药物溶液制剂
EP4495121A1 (en) Camptothecin derivatives that bind to ddx5 protein and prodrugs thereof
NZ551111A (en) Pharmaceutical solution formulations containing 17-AAG in a vehicle comprising ethanol, polyethoxylated castor oil, and a third component
US20070203110A1 (en) 17-Allylamino-17-demethoxygeldanamycin polymorphs and formulations
KR20070018117A (ko) 17-aag를 함유하는 약제학적 용제
US20090042847A1 (en) 17-allylamino-17-demethoxygeldanamycin polymorphs and formulations
Porter et al. Pharmaceutical development of IPI‐504, an Hsp90 inhibitor and clinical candidate for the treatment of cancer
CN118984706A (zh) 一种取代的1-(3,3-二氟哌啶-4-基)-咪唑并[4,5-c]喹啉-2-酮衍生物的晶型、其盐的晶型、制备方法及应用

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20110507