MXPA06000658A - Formulacion farmaceutica estable. - Google Patents

Formulacion farmaceutica estable.

Info

Publication number
MXPA06000658A
MXPA06000658A MXPA06000658A MXPA06000658A MXPA06000658A MX PA06000658 A MXPA06000658 A MX PA06000658A MX PA06000658 A MXPA06000658 A MX PA06000658A MX PA06000658 A MXPA06000658 A MX PA06000658A MX PA06000658 A MXPA06000658 A MX PA06000658A
Authority
MX
Mexico
Prior art keywords
active core
core composition
composition
quenching
gelatine capsule
Prior art date
Application number
MXPA06000658A
Other languages
English (en)
Inventor
Armin Knapp
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MXPA06000658A publication Critical patent/MXPA06000658A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion se refiere a una composicion farmaceutica en forma de capsula de gelatina, que comprende (a) una composicion activa de nucleo que comprende al menos un compuesto farmaceuticamente activo y opcionalmente adyuvantes farmaceuticos convencionales, (b) al menos una capa protectora de inactivacion, colocada entre dicha composicion de nucleo activo y la superficie interna de la envuelta de la capsula de gelatina, que comprende al menos un agente de inactivacion, pudiendo el agente activo unir quimicamente las impurezas volatiles que inician la reticulacion de la gelatina mediante una reaccion quimica sustancialmente reversible despues de que dichas impurezas se hayan liberado mediante adyuvantes y/o compuesto(s) activos de dicha composicion de nucleo activo y (c) un envuelta de capsula de gelatina que envuelve dicha composicion activa de nucleo incluyendo cualquier material adyuvante y cualquier capa de inactivacion anadida a la composicion de nucleo activo. Dicha composicion ha mejorado la capacidad de almacenamiento.
MXPA06000658A 2003-07-15 2004-07-05 Formulacion farmaceutica estable. MXPA06000658A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03016056A EP1498117A1 (en) 2003-07-15 2003-07-15 A pharmaceutical gelatin-capsule or gelatin containing capsule preparation showing an improved stability, a process for making the capsules and a process for improving the stability of gelatin-capsules
PCT/IB2004/002227 WO2005004839A2 (en) 2003-07-15 2004-07-05 Stable pharmaceutical formulation

Publications (1)

Publication Number Publication Date
MXPA06000658A true MXPA06000658A (es) 2006-03-30

Family

ID=33462122

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06000658A MXPA06000658A (es) 2003-07-15 2004-07-05 Formulacion farmaceutica estable.

Country Status (7)

Country Link
US (1) US20050053651A1 (es)
EP (2) EP1498117A1 (es)
JP (1) JP2007516210A (es)
BR (1) BRPI0412592A (es)
CA (1) CA2532337A1 (es)
MX (1) MXPA06000658A (es)
WO (1) WO2005004839A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
DE102007051059B4 (de) * 2007-10-18 2014-04-03 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen Bioverbundmaterial für die kontrollierte Freisetzung von Wirkstoffen
US8807070B2 (en) * 2008-08-07 2014-08-19 Vector Corporation Rotor processor for dry powders
US20100034967A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Dry polymer layering using a rotor processor
US20100034968A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Polymer coating process using dry glidant in a rotor processor
CN105434393B (zh) * 2014-09-25 2019-07-09 四川国为制药有限公司 一种包含高含量ω-3多不饱和脂肪酸的软胶囊药物组合物
JP6803250B2 (ja) * 2017-02-02 2020-12-23 共和薬品工業株式会社 エレトリプタン臭化水素酸塩含有口腔内崩壊錠

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US34545A (en) * 1862-02-25 Improvement in harvesters
JPS5115094B2 (es) * 1972-11-01 1976-05-14
JPS51101118A (ja) * 1975-02-28 1976-09-07 Eisai Co Ltd Nankapuseruhimaku
US4928840A (en) * 1986-02-25 1990-05-29 American Home Products Corporation Tamper proof encapsulated medicaments
US4867983A (en) * 1987-02-20 1989-09-19 Mcneilab, Inc. Method for double dipping gelating coated caplets
JPH062665B2 (ja) * 1987-10-06 1994-01-12 新田ゼラチン株式会社 ゼラチン組成物
JP2790659B2 (ja) * 1989-06-30 1998-08-27 帝国臓器製薬株式会社 ゼラチンカプセル剤
US5018822A (en) * 1989-12-11 1991-05-28 Litton Systems, Inc. Environmentally sealed multichannel fiber optic connector
US5460824A (en) * 1990-06-27 1995-10-24 Warner-Lambert Company Method for the preparation of an encapsulated medicament
JP3557008B2 (ja) * 1994-08-05 2004-08-25 塩野義製薬株式会社 変性の防止された硬質ゼラチンカプセル剤及びその製造方法
ES2151940T3 (es) * 1994-08-05 2001-01-16 Shionogi & Co Capsulas de gelatina dura resistentes a la desnaturalizacion y procedimiento para su preparacion.
US5620704A (en) * 1994-11-07 1997-04-15 Warner-Lambert Company Process for stabilizing gelatin products
HUP9900858A2 (hu) * 1995-06-07 1999-08-30 R.P. Scherer Corporation Eljárás és kompozíció töltőanyag átjutását gátló héjú lágy zselatinkapszulák előállítására
WO1997004755A1 (en) * 1995-08-02 1997-02-13 Warner-Lambert Company Hard gelatin capsules with low water transport and process for the production thereof
WO1997033568A1 (en) * 1996-03-12 1997-09-18 Novartis Ag Filled gelatin capsules having a reduced degree of cross-linking
JP2000026282A (ja) * 1998-07-14 2000-01-25 Shionogi & Co Ltd 溶出性が改善された硬ゼラチンカプセル剤
JP5196693B2 (ja) * 2001-05-02 2013-05-15 小川香料株式会社 非架橋ゼラチンカプセルの皮膜架橋防止方法

Also Published As

Publication number Publication date
JP2007516210A (ja) 2007-06-21
EP1656119A2 (en) 2006-05-17
CA2532337A1 (en) 2005-01-20
WO2005004839A3 (en) 2006-03-16
BRPI0412592A (pt) 2006-09-19
US20050053651A1 (en) 2005-03-10
WO2005004839A2 (en) 2005-01-20
EP1498117A1 (en) 2005-01-19

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