MXPA05010882A - Preparacion y purificacion de capsaicina sintetica. - Google Patents

Preparacion y purificacion de capsaicina sintetica.

Info

Publication number
MXPA05010882A
MXPA05010882A MXPA05010882A MXPA05010882A MXPA05010882A MX PA05010882 A MXPA05010882 A MX PA05010882A MX PA05010882 A MXPA05010882 A MX PA05010882A MX PA05010882 A MXPA05010882 A MX PA05010882A MX PA05010882 A MXPA05010882 A MX PA05010882A
Authority
MX
Mexico
Prior art keywords
purification
preparation
capsaicin
synthetic capsaicin
synthetic
Prior art date
Application number
MXPA05010882A
Other languages
English (en)
Inventor
B Carter Richard
Original Assignee
Algorx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Algorx Pharmaceuticals Inc filed Critical Algorx Pharmaceuticals Inc
Publication of MXPA05010882A publication Critical patent/MXPA05010882A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds

Abstract

La presente invencion proporciona metodos para sintetizar el isomero trans de capsaicina o compuestos similares a capsaicina, utilizando un proceso donde se fija la geometria trans desde el inicio de la reaccion de sintesis, y se sostiene durante todo el proceso de sintesis.
MXPA05010882A 2003-04-08 2004-04-08 Preparacion y purificacion de capsaicina sintetica. MXPA05010882A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46116403P 2003-04-08 2003-04-08
US53107403P 2003-12-18 2003-12-18
PCT/US2004/010745 WO2004092122A2 (en) 2003-04-08 2004-04-08 Preparation and purification of synthetic capsaicin

Publications (1)

Publication Number Publication Date
MXPA05010882A true MXPA05010882A (es) 2005-11-25

Family

ID=33303038

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05010882A MXPA05010882A (es) 2003-04-08 2004-04-08 Preparacion y purificacion de capsaicina sintetica.

Country Status (10)

Country Link
US (2) US20050085652A1 (es)
EP (1) EP1615880A4 (es)
JP (1) JP2006522815A (es)
AU (1) AU2004230915B2 (es)
BR (1) BRPI0409748A (es)
CA (1) CA2521925A1 (es)
EA (1) EA008705B1 (es)
MX (1) MXPA05010882A (es)
NZ (1) NZ542887A (es)
WO (1) WO2004092122A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2311756T3 (es) * 2002-12-18 2009-02-16 Algorx Administracion de la capsiacina.
DK1605956T3 (en) 2002-12-18 2016-02-15 Ct Xion Therapeutics Corp ADMINISTRATION OF CAPSAICINOIDS TO TREAT OSTEOARTHRITIS
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ES2535045T3 (es) 2003-04-10 2015-05-04 Vanderbilt Royalty Sub L.P. Usos y composiciones para administración de capsaicina
CA2596194A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
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ITMI20071603A1 (it) * 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
EP2453858B2 (en) * 2009-07-16 2017-09-13 Brightwake Limited Method
DK2629610T3 (da) 2010-07-27 2017-11-20 Flex Pharma Inc Fremgangsmåder og sammensætninger til forebyggelse og lindring af muskelkramper og til rehabilitering fra neuromuskulær irritabilitet og træthed efter træning
MX362804B (es) 2012-11-12 2019-02-14 Vizuri Health Sciences Llc Composiciones acuosas de capsaicinoides que comprenden un analgésico y un vehículo acuoso, y uso de las mismas para el tratamiento del dolor.
US20150133561A1 (en) 2013-11-12 2015-05-14 Vizuri Health Sciences Llc Aqueous based capsaicinoid formulations and methods of manufacture and use
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CN110453311A (zh) * 2019-09-23 2019-11-15 浙江理工大学 一种温感壳聚糖纤维及其制备方法
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CN117770450A (zh) * 2024-02-23 2024-03-29 天津福来特新材料科技有限公司 一种高纯度的辣椒素组合物及其制备方法和其应用

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Also Published As

Publication number Publication date
AU2004230915B2 (en) 2008-08-07
AU2004230915A1 (en) 2004-10-28
CA2521925A1 (en) 2004-10-28
EA200501582A1 (ru) 2006-06-30
NZ542887A (en) 2008-05-30
JP2006522815A (ja) 2006-10-05
US20050085652A1 (en) 2005-04-21
WO2004092122A2 (en) 2004-10-28
US20070293703A1 (en) 2007-12-20
EP1615880A2 (en) 2006-01-18
EA008705B1 (ru) 2007-06-29
EP1615880A4 (en) 2007-03-07
WO2004092122A3 (en) 2005-12-29
BRPI0409748A (pt) 2006-10-24

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