MXPA05009241A - Compuestos ester fosfato/sulfato y composiciones farmaceuticas para inhibir la proteina que interacciona con nima (pin1). - Google Patents
Compuestos ester fosfato/sulfato y composiciones farmaceuticas para inhibir la proteina que interacciona con nima (pin1).Info
- Publication number
- MXPA05009241A MXPA05009241A MXPA05009241A MXPA05009241A MXPA05009241A MX PA05009241 A MXPA05009241 A MX PA05009241A MX PA05009241 A MXPA05009241 A MX PA05009241A MX PA05009241 A MXPA05009241 A MX PA05009241A MX PA05009241 A MXPA05009241 A MX PA05009241A
- Authority
- MX
- Mexico
- Prior art keywords
- crdre
- mmol
- aryl
- alkyl
- nrbrc
- Prior art date
Links
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 18
- 229910019142 PO4 Inorganic materials 0.000 title abstract description 26
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 29
- 238000000034 method Methods 0.000 claims abstract description 24
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- 125000001072 heteroaryl group Chemical group 0.000 claims description 51
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- 125000001424 substituent group Chemical group 0.000 claims description 9
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- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
- C07F9/655354—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
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- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45316303P | 2003-03-10 | 2003-03-10 | |
PCT/IB2004/000574 WO2004087720A1 (fr) | 2003-03-10 | 2004-02-23 | Composes a base d'esters de sulfate/phosphate et compositions pharmaceutiques inhibant l'activite de nima interagissant avec des proteines (pin1) |
Publications (1)
Publication Number | Publication Date |
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MXPA05009241A true MXPA05009241A (es) | 2005-10-19 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MXPA05009241A MXPA05009241A (es) | 2003-03-10 | 2004-02-23 | Compuestos ester fosfato/sulfato y composiciones farmaceuticas para inhibir la proteina que interacciona con nima (pin1). |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1603926A1 (fr) |
JP (1) | JP2006523669A (fr) |
BR (1) | BRPI0408477A (fr) |
CA (1) | CA2517281A1 (fr) |
MX (1) | MXPA05009241A (fr) |
WO (1) | WO2004087720A1 (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005080406A2 (fr) * | 2003-12-19 | 2005-09-01 | Jerini Ag | Composes chimiques pour l'inhibition de proliferation cellulaire indesirable et leurs utilisation |
US7618981B2 (en) * | 2004-05-06 | 2009-11-17 | Cytokinetics, Inc. | Imidazopyridinyl-benzamide anti-cancer agents |
US7795448B2 (en) | 2004-05-06 | 2010-09-14 | Cytokinetics, Incorporated | Imidazoyl-benzamide anti-cancer agents |
US7504413B2 (en) | 2004-05-06 | 2009-03-17 | Cytokinetics, Inc. | N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases |
WO2006040646A1 (fr) * | 2004-10-14 | 2006-04-20 | Pfizer, Inc. | Amides de benzimidazole ou d'indole en tant qu'inhibiteurs de pin1 |
EP2845588A1 (fr) * | 2013-09-09 | 2015-03-11 | Centre National de la Recherche Scientifique (C.N.R.S.) | Inhibiteurs PIN1 destiné à être utilisé dans la prévention et/ou le traitement de theileriosis et applications associées |
SI3201196T1 (sl) | 2014-10-03 | 2021-12-31 | UCB Biopharma SRL | Derivati kondenziranega pentacikličnega imidazola |
WO2017063757A1 (fr) | 2015-10-12 | 2017-04-20 | Polyphor Ag | Composés macrocycliques à conformation limitée |
WO2017063755A1 (fr) | 2015-10-12 | 2017-04-20 | Polyphor Ag | Composés macrocycliques à conformation limitée |
WO2017063754A1 (fr) | 2015-10-12 | 2017-04-20 | Polyphor Ag | Utilisation de composés macrocycliques à conformation limitée comme modulateurs de pin1 |
WO2017063756A1 (fr) * | 2015-10-12 | 2017-04-20 | Polyphor Ag | Utilisation de composés macrocycliques à conformation limitée comme modulateurs de pin1 |
EA201892142A1 (ru) | 2016-04-01 | 2019-04-30 | Юсб Байофарма Спрл | Конденсированные пентациклические производные имидазола в качестве модуляторов активности tnf |
CA3018992A1 (fr) | 2016-04-01 | 2017-10-05 | Ucb Biopharma Sprl | Derives d'imidazole hexacycliques condenses utilises en tant que modulateurs de l'activite du tnf |
CA3018907A1 (fr) | 2016-04-01 | 2017-10-05 | Ucb Biopharma Sprl | Derives d'imidazole pentacycliques condenses utilises en tant que modulateurs de l'activite du tnf |
CA3019026A1 (fr) | 2016-04-01 | 2017-10-05 | Ucb Biopharma Sprl | Derives d'imidazole pentacycliques condenses utilises en tant que modulateurs de l'activite du tnf |
WO2018101329A1 (fr) | 2016-11-29 | 2018-06-07 | 国立大学法人広島大学 | Nouveau composé ester et inhibiteur de pin1, agent thérapeutique pour maladie inflammatoire et agent thérapeutique pour cancer du côlon dans lesquels ledit composé ester est utilisé |
TWI784370B (zh) * | 2017-01-31 | 2022-11-21 | 美商基利科學股份有限公司 | 替諾福韋埃拉酚胺(tenofovir alafenamide)之晶型 |
JP7121033B2 (ja) | 2017-03-15 | 2022-08-17 | ユーシービー バイオファルマ エスアールエル | Tnf活性のモジュレーターとしての縮合五環式イミダゾール誘導体 |
EP3680232A4 (fr) | 2017-08-07 | 2021-08-11 | Hiroshima University | NOUVEAU COMPOSÉ À BASE D'ACIDE ANTHRANILIQUE, ET INHIBITEUR DE Pin1, AGENT THÉRAPEUTIQUE CONTRE LES MALADIES INFLAMMATOIRES AINSI QU'AGENT THÉRAPEUTIQUE CONTRE LE CANCER METTANT EN UVRE CELUI-CI |
WO2019031471A1 (fr) | 2017-08-07 | 2019-02-14 | 国立大学法人広島大学 | Agent thérapeutique contre la stéatose hépatique, et agent thérapeutique contre l'obésité |
CN111201215B (zh) | 2017-08-07 | 2024-01-26 | 国立大学法人广岛大学 | 新型酰胺系化合物、使用了该化合物的Pin1抑制剂、炎症性疾病的治疗剂及癌症的治疗剂 |
CN115397466A (zh) | 2020-03-12 | 2022-11-25 | 国立大学法人广岛大学 | 新型3,5-二氨基苯甲酸系化合物和使用该化合物的Pin1抑制剂以及炎症性疾病的治疗剂 |
WO2022032179A1 (fr) * | 2020-08-07 | 2022-02-10 | The Regents Of The University Of California | Inhibiteurs de pin1 et utilisations associées |
JP2022080079A (ja) | 2020-11-17 | 2022-05-27 | 国立大学法人広島大学 | Covid-19の治療剤又は予防剤 |
WO2022270628A1 (fr) * | 2021-06-25 | 2022-12-29 | 国立大学法人 大分大学 | Dérivé de polyhétéroazole substitué par hétérocycloalkyle utilisé en tant que médicament pour le traitement et/ou la prévention d'une maladie infectieuse à virus rs |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508387A (en) * | 1993-08-04 | 1996-04-16 | Glycomed Incorporated | Selectin binding glycopeptides |
WO2004005315A2 (fr) * | 2002-07-09 | 2004-01-15 | Pfizer Inc. | Polypeptides isomerase peptidyl-prolyl pin1, leurs structures cristallines, et leur utilisation dans la conception de medicament |
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2004
- 2004-02-23 BR BRPI0408477-2A patent/BRPI0408477A/pt not_active IP Right Cessation
- 2004-02-23 WO PCT/IB2004/000574 patent/WO2004087720A1/fr not_active Application Discontinuation
- 2004-02-23 CA CA002517281A patent/CA2517281A1/fr not_active Abandoned
- 2004-02-23 EP EP04713610A patent/EP1603926A1/fr not_active Withdrawn
- 2004-02-23 MX MXPA05009241A patent/MXPA05009241A/es unknown
- 2004-02-23 JP JP2006506287A patent/JP2006523669A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1603926A1 (fr) | 2005-12-14 |
WO2004087720A1 (fr) | 2004-10-14 |
JP2006523669A (ja) | 2006-10-19 |
CA2517281A1 (fr) | 2004-10-14 |
BRPI0408477A (pt) | 2006-04-04 |
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