MXPA05000287A - Particula viral adyuvante. - Google Patents
Particula viral adyuvante.Info
- Publication number
- MXPA05000287A MXPA05000287A MXPA05000287A MXPA05000287A MXPA05000287A MX PA05000287 A MXPA05000287 A MX PA05000287A MX PA05000287 A MXPA05000287 A MX PA05000287A MX PA05000287 A MXPA05000287 A MX PA05000287A MX PA05000287 A MXPA05000287 A MX PA05000287A
- Authority
- MX
- Mexico
- Prior art keywords
- immunogen
- vlp
- protein
- virus
- carrier complex
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
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- A—HUMAN NECESSITIES
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- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
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- C12N2770/26011—Flexiviridae
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US8101189B2 (en) | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
| ES2431963T3 (es) * | 2002-07-05 | 2013-11-28 | Folia Biotech Inc. | Partícula viral adyuvante |
| MX2007003171A (es) * | 2004-09-21 | 2007-05-23 | Cytos Biotechnology Ag | Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico. |
| AU2005298689A1 (en) | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| KR100688522B1 (ko) * | 2005-01-18 | 2007-03-02 | 삼성전자주식회사 | 영상데이터 압축기 및 압축방법 |
| BRPI0611336A2 (pt) | 2005-06-01 | 2010-08-31 | Dow Global Technologies Inc | método para produzir uma partìcula multivalente semelhante a vìrus, partìcula multivalente semelhante a vìrus, método de aumentar a solubilidade de uma partìcula multivalente semelhante a vìrus e vacina |
| AT503690A1 (de) | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
| JP2010508857A (ja) * | 2006-11-15 | 2010-03-25 | フォリア バイオテック インコーポレイテッド | パパイヤモザイクウイルスに基づく免疫原性の親和性で複合体化された抗原系及びその使用 |
| WO2012048430A1 (en) * | 2010-10-14 | 2012-04-19 | Folia Biotech Inc. | Affinity-conjugated nucleoprotein-papaya mosaic virus-like particles and uses thereof |
| CA2669485C (en) * | 2006-11-15 | 2017-01-03 | Folia Biotech Inc. | Papaya mosaic virus-based vaccines for influenza |
| US20100316665A1 (en) * | 2007-01-26 | 2010-12-16 | Denis Leclerc | Papaya mosaic virus-based vaccines against salmonella typhi and other enterobacterial pathogens |
| CN101784655A (zh) * | 2007-04-27 | 2010-07-21 | 菲尼克斯股份有限公司 | 可溶性重组二十面体病毒样颗粒的改良生成和体内装配 |
| JP2010538619A (ja) * | 2007-09-11 | 2010-12-16 | ユニベルシテ ラヴァル | Ｍａｌｖａモザイクウイルスおよびウイルス様粒子およびこれらの使用 |
| US20110189231A1 (en) * | 2008-06-17 | 2011-08-04 | Denis Leclerc | Compositions Comprising Salmonella Porins and Uses Thereof as Adjuvants and Vaccines |
| WO2010012069A1 (en) * | 2008-07-30 | 2010-02-04 | Folio Biotech Inc. | Multivalent vaccines based on papaya mosaic virus and uses thereof |
| US20130236491A1 (en) * | 2010-12-09 | 2013-09-12 | Iosif Grigorievich Atabekov | Spherical nano and microparticles derived from plant viruses for the display of foreign proteins or epitopes |
| US20140154288A1 (en) | 2011-05-13 | 2014-06-05 | Folia Biotech Inc. | Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response |
| RU2630652C2 (ru) | 2011-06-09 | 2017-09-11 | Биомей Аг | Гибридные белки-носители пептидов в качестве вакцин от аллергии |
| EP2834274A4 (en) * | 2012-04-02 | 2015-11-11 | Folia Biotech Inc | RECOMBINANT PAPAYAMOSA VIRUS WRAPPER PROTEINS AND USES THEREOF IN FLUID VACCINATES |
| US20160228541A1 (en) * | 2013-09-19 | 2016-08-11 | Alain Lamarre | Papaya mosaic virus and virus-like particles in cancer therapy |
| WO2016176558A1 (en) * | 2015-04-30 | 2016-11-03 | The Regents Of The University Of California | Adjuvant particles comprising adenosine receptor antagonists |
| BR112022019647A2 (pt) * | 2020-03-31 | 2022-11-29 | Mediphage Bioceuticals Inc | Vetores para produção de partículas semelhantes a vírus e usos das mesmas |
| CA3208643A1 (en) | 2021-01-18 | 2022-07-21 | Conserv Bioscience Limited | Coronavirus immunogenic compositions, methods and uses thereof |
| CN118684781A (zh) * | 2023-03-21 | 2024-09-24 | 深圳赫兹生命科学技术有限公司 | GnRH-VLP重组去势疫苗及其制备方法 |
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| IL79880A0 (en) | 1985-08-29 | 1986-11-30 | Inst Medical W & E Hall | Recombinant virus |
| US5977438A (en) * | 1988-02-26 | 1999-11-02 | Biosource Technologies, Inc. | Production of peptides in plants as viral coat protein fusions |
| DE4006630A1 (de) | 1990-03-03 | 1991-09-12 | Behringwerke Ag | Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung |
| EP0652967B1 (en) | 1990-08-15 | 1998-02-04 | Therion Biologics Corporation | Self-assembling replication defective hybrid virus particles |
| US5443969A (en) * | 1992-10-29 | 1995-08-22 | Rutgers University | RNA packaging system |
| GB9414118D0 (en) * | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| CA2202761A1 (en) | 1994-10-18 | 1996-04-25 | Sean Nicholas Chapman | Method of producing a chimeric protein |
| GB9607899D0 (en) | 1996-04-17 | 1996-06-19 | Scottish Crop Research Inst | Virus-like particle |
| US6042832A (en) | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| AU750702B2 (en) * | 1997-05-01 | 2002-07-25 | Chiron Corporation | Use of virus-like particles as adjuvants |
| US6228368B1 (en) | 1997-10-06 | 2001-05-08 | Loyola University Of Chicago | Papilloma virus capsomere formulations and method of use |
| DE19752855C2 (de) | 1997-11-28 | 2003-04-03 | Bundesrepublik Deutschland Let | Retrovirale Pseudotyp-Vektoren mit modifizierten Oberflächen-Hüllproteinen und Verpackungszelle zu ihrer Herstellung für den selektiven Gentransfer |
| GB9806666D0 (en) | 1998-03-27 | 1998-05-27 | Stanley Margaret | Antigen preparation and use |
| JP2002522029A (ja) | 1998-07-27 | 2002-07-23 | ジェネンテック・インコーポレーテッド | コートタンパク質の改変によるファージ提示における改良した形質転換効率 |
| FR2786773B1 (fr) | 1998-12-03 | 2002-03-08 | Univ Paris Curie | Proteines d'enveloppe, methodes et utilisations |
| TR200102423T2 (tr) * | 1998-12-04 | 2002-02-21 | Biogen, Inc. | Peptid ligandları yoluyla bağlı birden fazla imünojenik bileşeni olan HBV çekirdek antijeni parçacıkları |
| DE19904800C1 (de) * | 1999-02-05 | 2001-02-08 | Eberhard Hildt | Partikel zur Gentherapie |
| GB9921337D0 (en) * | 1999-09-09 | 1999-11-10 | Axis Genetics Plc | Modified plant viruses |
| GB9924351D0 (en) * | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
| GB9924352D0 (en) | 1999-10-14 | 1999-12-15 | Hellendoorn Koen | Methods,compositions and applications relating to the generation of novel plant viral particles |
| US6730306B1 (en) | 2000-03-08 | 2004-05-04 | Large Scale Biology Corporation | Parvovirus vaccine as viral coat protein fusions |
| AUPQ661600A0 (en) | 2000-03-31 | 2000-05-04 | Macfarlane Burnet Centre For Medical Research Limited, The | A nucleic acid construct and methods related thereto |
| IT1317046B1 (it) * | 2000-06-16 | 2003-05-26 | Ist Superiore Sanita | Proteina di fusione, particelle virali chimeriche che la espongono sulcapside, piante infettate con tali particelle, loro usi e composizioni |
| CA2414396A1 (en) | 2000-06-26 | 2002-01-03 | The United States Of America, As Represented By The Secretary Of Agricul Ture | Production of vaccines using transgenic plants |
| WO2002004007A2 (en) | 2000-07-06 | 2002-01-17 | Georgetown University | Stable (fixed) forms of viral capsid proteins, fusion proteins and uses thereof |
| GB0028319D0 (en) * | 2000-11-20 | 2001-01-03 | Univ Southampton | Materials and methods relating to fusion proteins for inducing an immune response |
| ITRM20010332A1 (it) * | 2001-06-11 | 2002-12-11 | Ist Superiore Sanita | Vaccini a subunita' e procedimenti per la loro produzione. |
| ES2431963T3 (es) * | 2002-07-05 | 2013-11-28 | Folia Biotech Inc. | Partícula viral adyuvante |
| US8101189B2 (en) * | 2002-07-05 | 2012-01-24 | Folia Biotech Inc. | Vaccines and immunopotentiating compositions and methods for making and using them |
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2003
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- 2003-06-30 EP EP10179379A patent/EP2272525A3/en not_active Withdrawn
- 2003-06-30 MX MXPA05000287A patent/MXPA05000287A/es active IP Right Grant
- 2003-06-30 PT PT37399136T patent/PT1523329E/pt unknown
- 2003-06-30 WO PCT/CA2003/000985 patent/WO2004004761A2/en not_active Ceased
- 2003-06-30 BR BR0312474-6A patent/BR0312474A/pt not_active Application Discontinuation
- 2003-06-30 EP EP03739913.6A patent/EP1523329B1/en not_active Expired - Lifetime
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- 2003-06-30 KR KR1020057000114A patent/KR20050044886A/ko not_active Withdrawn
- 2003-06-30 AU AU2003281246A patent/AU2003281246A1/en not_active Abandoned
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2005
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2009
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| AU2003281246A1 (en) | 2004-01-23 |
| EP2272525A2 (en) | 2011-01-12 |
| BR0312474A (pt) | 2005-04-26 |
| CA2434000C (en) | 2012-07-17 |
| WO2004004761A3 (en) | 2004-05-06 |
| JP4953570B2 (ja) | 2012-06-13 |
| CA2434000A1 (en) | 2004-01-05 |
| EP2272525A3 (en) | 2011-11-16 |
| EP1523329B1 (en) | 2013-07-24 |
| US20050048082A1 (en) | 2005-03-03 |
| EP1523329A2 (en) | 2005-04-20 |
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| HK1075214A1 (en) | 2005-12-09 |
| NO20050396L (no) | 2005-01-25 |
| US8282940B2 (en) | 2012-10-09 |
| JP2006504644A (ja) | 2006-02-09 |
| CN1665528A (zh) | 2005-09-07 |
| WO2004004761A2 (en) | 2004-01-15 |
| ES2431963T3 (es) | 2013-11-28 |
| CN1665528B (zh) | 2013-05-15 |
| KR20050044886A (ko) | 2005-05-13 |
| US7641896B2 (en) | 2010-01-05 |
| PT1523329E (pt) | 2013-10-08 |
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