MXPA04011372A - Diaminotiazoles. - Google Patents
Diaminotiazoles.Info
- Publication number
- MXPA04011372A MXPA04011372A MXPA04011372A MXPA04011372A MXPA04011372A MX PA04011372 A MXPA04011372 A MX PA04011372A MX PA04011372 A MXPA04011372 A MX PA04011372A MX PA04011372 A MXPA04011372 A MX PA04011372A MX PA04011372 A MXPA04011372 A MX PA04011372A
- Authority
- MX
- Mexico
- Prior art keywords
- amino
- phenylamino
- thiazol
- methanone
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38151302P | 2002-05-17 | 2002-05-17 | |
| PCT/EP2003/004939 WO2003097048A1 (en) | 2002-05-17 | 2003-05-12 | Diaminothiazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04011372A true MXPA04011372A (es) | 2005-08-15 |
Family
ID=29550137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04011372A MXPA04011372A (es) | 2002-05-17 | 2003-05-12 | Diaminotiazoles. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6818663B2 (pl) |
| EP (1) | EP1507530B1 (pl) |
| JP (1) | JP4308133B2 (pl) |
| KR (1) | KR100619515B1 (pl) |
| CN (1) | CN100400041C (pl) |
| AR (1) | AR040078A1 (pl) |
| AT (1) | ATE308323T1 (pl) |
| AU (1) | AU2003232754B2 (pl) |
| BR (1) | BR0310081A (pl) |
| CA (1) | CA2485367A1 (pl) |
| DE (1) | DE60302152T2 (pl) |
| ES (1) | ES2251697T3 (pl) |
| MX (1) | MXPA04011372A (pl) |
| PL (1) | PL374581A1 (pl) |
| RU (1) | RU2311414C2 (pl) |
| WO (1) | WO2003097048A1 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070167329A1 (en) * | 2003-12-24 | 2007-07-19 | Bayer Cropscience Gmbh | Plant growth regulation |
| US7211576B2 (en) * | 2004-04-20 | 2007-05-01 | Hoffmann-La Roche Inc. | Diaminothiazoles |
| US7405220B2 (en) | 2004-06-09 | 2008-07-29 | Hoffmann-La Roche Inc. | Pyrazolopyrimidines |
| US7705009B2 (en) * | 2005-11-22 | 2010-04-27 | Hoffman-La Roche Inc. | 4-aminopyrimidine-5-thione derivatives |
| WO2008054702A1 (en) | 2006-10-31 | 2008-05-08 | Schering Corporation | Anilinopiperazine derivatives and methods of use thereof |
| US8318735B2 (en) | 2006-10-31 | 2012-11-27 | Merck Sharp & Dohme Corp. | 2-aminothiazole-4-carboxylic amides as protein kinase inhibitors |
| CA2733682C (en) * | 2008-08-12 | 2014-10-14 | Air Products And Chemicals, Inc. | Polymeric compositions comprising per(phenylethynyl) arene derivatives |
| EP2608671B1 (en) * | 2010-08-24 | 2018-12-12 | Gtx, Inc. | Compounds for treatment of cancer |
| US9006353B2 (en) | 2011-11-18 | 2015-04-14 | Delsper LP | Crosslinking compounds for high glass transition temperature polymers |
| EP2986740B1 (en) | 2013-04-16 | 2020-01-15 | Memorial Sloan-Kettering Cancer Center | Companion diagnostic for cdk4 inhibitors |
| WO2015051525A1 (en) * | 2013-10-11 | 2015-04-16 | Rhodia Operations | Synthesis of acetal/ketal |
| US11921116B2 (en) | 2016-03-09 | 2024-03-05 | Memorial Sloan Kettering Cancer Center | Enigma and CDH18 as companion diagnostics for CDK4 inhibitors |
| WO2017158147A1 (en) | 2016-03-18 | 2017-09-21 | Savira Pharmaceuticals Gmbh | Pyrimidone derivatives and their use in the treatment, amelioration or prevention of a viral disease |
| WO2018089902A1 (en) * | 2016-11-13 | 2018-05-17 | Apogee Biotechnology Corporation | Diaminothiazole compounds, compositions and methods of use |
| CN110950848B (zh) * | 2018-09-27 | 2024-03-26 | 徐诺药业 | 新型氨基吡唑类衍生物的合成与应用 |
| KR20220002316A (ko) | 2019-04-30 | 2022-01-06 | 인스티튜토 데 메디시나 몰레큘라 조앙 로보 안투네스 | Cdk 억제제와 조합된 rank 경로 억제제 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL135574A0 (en) * | 1997-10-27 | 2001-05-20 | Agouron Pharma | Substituted 4-amino-thiazol-2-yl compounds as cdk inhibitors |
| UA71971C2 (en) * | 1999-06-04 | 2005-01-17 | Agoron Pharmaceuticals Inc | Diaminothiazoles, composition based thereon, a method for modulation of protein kinases activity, a method for the treatment of diseases mediated by protein kinases |
| JP2004505983A (ja) * | 2000-08-09 | 2004-02-26 | アグーロン ファーマシューティカルズ，インコーポレイテッド | ピラゾール−チアゾール化合物、これらを含む医薬組成物、およびサイクリン依存性キナーゼの阻害のためのこれらの使用方法 |
| US6756374B2 (en) | 2001-01-22 | 2004-06-29 | Hoffmann-La Roche Inc. | Diaminothiazoles having antiproliferative activity |
-
2003
- 2003-05-05 US US10/429,551 patent/US6818663B2/en not_active Expired - Fee Related
- 2003-05-12 EP EP03752731A patent/EP1507530B1/en not_active Expired - Lifetime
- 2003-05-12 RU RU2004137110/04A patent/RU2311414C2/ru active
- 2003-05-12 WO PCT/EP2003/004939 patent/WO2003097048A1/en active IP Right Grant
- 2003-05-12 CN CNB038111314A patent/CN100400041C/zh not_active Expired - Fee Related
- 2003-05-12 MX MXPA04011372A patent/MXPA04011372A/es active IP Right Grant
- 2003-05-12 BR BR0310081-2A patent/BR0310081A/pt not_active IP Right Cessation
- 2003-05-12 PL PL03374581A patent/PL374581A1/pl not_active Application Discontinuation
- 2003-05-12 CA CA002485367A patent/CA2485367A1/en not_active Abandoned
- 2003-05-12 JP JP2004505047A patent/JP4308133B2/ja not_active Expired - Fee Related
- 2003-05-12 DE DE60302152T patent/DE60302152T2/de not_active Expired - Fee Related
- 2003-05-12 AU AU2003232754A patent/AU2003232754B2/en not_active Ceased
- 2003-05-12 AT AT03752731T patent/ATE308323T1/de not_active IP Right Cessation
- 2003-05-12 ES ES03752731T patent/ES2251697T3/es not_active Expired - Lifetime
- 2003-05-12 KR KR1020047018605A patent/KR100619515B1/ko not_active IP Right Cessation
- 2003-05-15 AR ARP030101692A patent/AR040078A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US6818663B2 (en) | 2004-11-16 |
| EP1507530B1 (en) | 2005-11-02 |
| US20040006058A1 (en) | 2004-01-08 |
| RU2004137110A (ru) | 2005-08-20 |
| DE60302152D1 (de) | 2005-12-08 |
| AR040078A1 (es) | 2005-03-16 |
| KR20050006261A (ko) | 2005-01-15 |
| JP2005530783A (ja) | 2005-10-13 |
| DE60302152T2 (de) | 2006-07-13 |
| BR0310081A (pt) | 2005-02-15 |
| ATE308323T1 (de) | 2005-11-15 |
| ES2251697T3 (es) | 2006-05-01 |
| AU2003232754B2 (en) | 2009-03-12 |
| EP1507530A1 (en) | 2005-02-23 |
| KR100619515B1 (ko) | 2006-09-08 |
| PL374581A1 (pl) | 2005-10-31 |
| JP4308133B2 (ja) | 2009-08-05 |
| AU2003232754A1 (en) | 2003-12-02 |
| CN100400041C (zh) | 2008-07-09 |
| WO2003097048A1 (en) | 2003-11-27 |
| CN1652780A (zh) | 2005-08-10 |
| RU2311414C2 (ru) | 2007-11-27 |
| CA2485367A1 (en) | 2003-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |