MXPA04004412A - Antagonsitas del receptor nmda y su uso para inhibir la hiperfosforilacion anormal de la proteina tau asociada a microtubulos. - Google Patents
Antagonsitas del receptor nmda y su uso para inhibir la hiperfosforilacion anormal de la proteina tau asociada a microtubulos.Info
- Publication number
- MXPA04004412A MXPA04004412A MXPA04004412A MXPA04004412A MXPA04004412A MX PA04004412 A MXPA04004412 A MX PA04004412A MX PA04004412 A MXPA04004412 A MX PA04004412A MX PA04004412 A MXPA04004412 A MX PA04004412A MX PA04004412 A MXPA04004412 A MX PA04004412A
- Authority
- MX
- Mexico
- Prior art keywords
- amino
- adamantane
- tau
- condition
- memantine
- Prior art date
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- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
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- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
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- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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Applications Claiming Priority (3)
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| US35097401P | 2001-11-07 | 2001-11-07 | |
| US33785801P | 2001-11-08 | 2001-11-08 | |
| PCT/GB2002/005038 WO2003040084A1 (en) | 2001-11-07 | 2002-11-07 | Unsaturated 1-amino-alkylcyclohexane nmda, 5ht3 and neuronal nicotinic receptor antagonists |
Publications (1)
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| MXPA04004412A true MXPA04004412A (es) | 2005-05-16 |
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| TW593223B (en) * | 2000-06-20 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists |
| AU2004258751C1 (en) * | 2003-07-28 | 2008-07-17 | Merz Pharma Gmbh & Co. Kgaa | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity |
| AR046314A1 (es) * | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
| TW200531680A (en) * | 2004-03-03 | 2005-10-01 | Merz Pharma Gmbh & Co Kgaa | Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease |
| EP2601937A1 (en) * | 2004-06-17 | 2013-06-12 | Merz Pharma GmbH & Co. KGaA | Drinkable immediate release tablet made with direct compression of memantine or neramexane |
| US7427601B2 (en) * | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| US7893289B2 (en) * | 2007-02-21 | 2011-02-22 | Ssv Therapeutics, Inc. | Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids |
| EP2111858A1 (en) | 2008-04-25 | 2009-10-28 | EPFL Ecole Polytechnique Fédérale de Lausanne | Novel treatment for alzheimer's disease |
| US20090275597A1 (en) * | 2008-05-02 | 2009-11-05 | Forest Laboratories Holdings Limited | Methods of treating cns disorders |
| PE20150362A1 (es) | 2008-08-12 | 2015-03-20 | Zinfandel Pharmaceuticals Inc | Metodo de identificacion de factores de riesgo de la enfermedad |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| CA2824050A1 (en) | 2011-01-10 | 2012-07-19 | Zinfandel Pharmaceuticals, Inc. | Methods and drug products for treating alzheimer's disease |
| US20150182546A1 (en) * | 2013-03-15 | 2015-07-02 | Mitochondrial Concepts Llc | Therapeutic agent for enhancing mitochondrial function |
| US10556853B2 (en) | 2017-01-10 | 2020-02-11 | Owen-Barry Pharmaceuticals Inc. | Anticonvulsant compounds |
| AU2024287244B1 (en) * | 2024-12-28 | 2025-08-21 | Lai, Meng Hong MR | A device for relieving constipation and its preparation method |
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| US4267366A (en) * | 1977-12-14 | 1981-05-12 | Scm Corporation | Cyclic terpenoid amines, their preparation and uses |
| US6071966A (en) | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
| ES2200358T3 (es) * | 1997-06-30 | 2004-03-01 | MERZ PHARMA GMBH & CO. KGAA | 1-amino-alquilciclohexanos antagonistas del receptor de nmda. |
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| EP1442008A1 (en) | 2004-08-04 |
| HUP0402028A3 (en) | 2008-03-28 |
| CA2465738C (en) | 2009-01-20 |
| CN1602292A (zh) | 2005-03-30 |
| EA200400637A1 (ru) | 2004-10-28 |
| IL161801A0 (en) | 2005-11-20 |
| CO5570696A2 (es) | 2005-10-31 |
| US6828462B2 (en) | 2004-12-07 |
| EA010177B1 (ru) | 2008-06-30 |
| JP2005508381A (ja) | 2005-03-31 |
| CN100390131C (zh) | 2008-05-28 |
| CA2465738A1 (en) | 2003-05-15 |
| GEP20053714B (en) | 2005-12-26 |
| US20030166634A1 (en) | 2003-09-04 |
| KR20050044354A (ko) | 2005-05-12 |
| NO20042338L (no) | 2004-07-21 |
| PL370245A1 (en) | 2005-05-16 |
| WO2003040084A1 (en) | 2003-05-15 |
| HUP0402028A2 (hu) | 2005-01-28 |
| AU2002337389B2 (en) | 2005-12-08 |
| HK1075037A1 (zh) | 2005-12-02 |
| KR100655975B1 (ko) | 2006-12-08 |
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