NO20042338L - Umettede 1-aminoalkylsykloheksan-NMDA-, 5HT3- og nevronale nikotinsyrereseptorantagonister - Google Patents
Umettede 1-aminoalkylsykloheksan-NMDA-, 5HT3- og nevronale nikotinsyrereseptorantagonisterInfo
- Publication number
- NO20042338L NO20042338L NO20042338A NO20042338A NO20042338L NO 20042338 L NO20042338 L NO 20042338L NO 20042338 A NO20042338 A NO 20042338A NO 20042338 A NO20042338 A NO 20042338A NO 20042338 L NO20042338 L NO 20042338L
- Authority
- NO
- Norway
- Prior art keywords
- aminoalkylcyclohexane
- nmda
- unsaturated
- receptor antagonists
- nicotinic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P27/02—Ophthalmic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
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- A61P33/06—Antimalarials
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/25—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35097401P | 2001-11-07 | 2001-11-07 | |
| US33785801P | 2001-11-08 | 2001-11-08 | |
| PCT/GB2002/005038 WO2003040084A1 (en) | 2001-11-07 | 2002-11-07 | Unsaturated 1-amino-alkylcyclohexane nmda, 5ht3 and neuronal nicotinic receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20042338L true NO20042338L (no) | 2004-07-21 |
Family
ID=26990903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20042338A NO20042338L (no) | 2001-11-07 | 2004-06-04 | Umettede 1-aminoalkylsykloheksan-NMDA-, 5HT3- og nevronale nikotinsyrereseptorantagonister |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6828462B2 (no) |
| EP (1) | EP1442008A1 (no) |
| JP (1) | JP2005508381A (no) |
| KR (1) | KR100655975B1 (no) |
| CN (1) | CN100390131C (no) |
| AU (1) | AU2002337389B2 (no) |
| CA (1) | CA2465738C (no) |
| CO (1) | CO5570696A2 (no) |
| EA (1) | EA010177B1 (no) |
| GE (1) | GEP20053714B (no) |
| HK (1) | HK1075037A1 (no) |
| HU (1) | HUP0402028A3 (no) |
| IL (1) | IL161801A0 (no) |
| MX (1) | MXPA04004412A (no) |
| NO (1) | NO20042338L (no) |
| PL (1) | PL370245A1 (no) |
| WO (1) | WO2003040084A1 (no) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW593223B (en) * | 2000-06-20 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists |
| WO2005009421A2 (en) * | 2003-07-28 | 2005-02-03 | Merz Pharma Gmbh & Co. Kgaa | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity |
| AR046314A1 (es) * | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
| TW200531680A (en) * | 2004-03-03 | 2005-10-01 | Merz Pharma Gmbh & Co Kgaa | Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease |
| CN101389315A (zh) * | 2004-06-17 | 2009-03-18 | 莫茨药物股份两合公司 | 美金刚口服剂型即释制剂 |
| US7427601B2 (en) * | 2004-06-24 | 2008-09-23 | Schwarz Pharma Ag | Method for treating tremor |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| EP2117315A1 (en) * | 2007-02-21 | 2009-11-18 | SSV Therapeutics, Inc. | Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids |
| EP2111858A1 (en) | 2008-04-25 | 2009-10-28 | EPFL Ecole Polytechnique Fédérale de Lausanne | Novel treatment for alzheimer's disease |
| US20090275597A1 (en) * | 2008-05-02 | 2009-11-05 | Forest Laboratories Holdings Limited | Methods of treating cns disorders |
| EP2324126B1 (en) | 2008-08-12 | 2014-04-23 | Zinfandel Pharmaceuticals, Inc. | METHOD OF IDENTIFYING Alzheimer's DISEASE RISK FACTORS |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| MA34828B1 (fr) | 2011-01-10 | 2014-01-02 | Zinfandel Pharmaceuticals Inc | Procédés et produits médicamenteux destinés au traitement de la maladie d'alzheimer |
| US20150182546A1 (en) * | 2013-03-15 | 2015-07-02 | Mitochondrial Concepts Llc | Therapeutic agent for enhancing mitochondrial function |
| EP3568388A4 (en) * | 2017-01-10 | 2020-10-14 | Owen-Barry Pharmaceuticals Inc. | ANTICONVULSIVE CONNECTIONS |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4267366A (en) * | 1977-12-14 | 1981-05-12 | Scm Corporation | Cyclic terpenoid amines, their preparation and uses |
| TW593225B (en) * | 1997-06-30 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane NMDA receptor antagonists |
| US6071966A (en) | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
-
2002
- 2002-11-06 US US10/288,819 patent/US6828462B2/en not_active Expired - Fee Related
- 2002-11-07 EA EA200400637A patent/EA010177B1/ru not_active IP Right Cessation
- 2002-11-07 JP JP2003542132A patent/JP2005508381A/ja active Pending
- 2002-11-07 PL PL02370245A patent/PL370245A1/xx not_active Application Discontinuation
- 2002-11-07 WO PCT/GB2002/005038 patent/WO2003040084A1/en active IP Right Grant
- 2002-11-07 KR KR1020047006901A patent/KR100655975B1/ko not_active IP Right Cessation
- 2002-11-07 MX MXPA04004412A patent/MXPA04004412A/es active IP Right Grant
- 2002-11-07 IL IL16180102A patent/IL161801A0/xx unknown
- 2002-11-07 CN CNB02824530XA patent/CN100390131C/zh not_active Expired - Fee Related
- 2002-11-07 AU AU2002337389A patent/AU2002337389B2/en not_active Ceased
- 2002-11-07 CA CA002465738A patent/CA2465738C/en not_active Expired - Fee Related
- 2002-11-07 HU HU0402028A patent/HUP0402028A3/hu unknown
- 2002-11-07 GE GE5600A patent/GEP20053714B/en unknown
- 2002-11-07 EP EP02772631A patent/EP1442008A1/en not_active Withdrawn
-
2004
- 2004-05-06 CO CO04041831A patent/CO5570696A2/es not_active Application Discontinuation
- 2004-06-04 NO NO20042338A patent/NO20042338L/no not_active Application Discontinuation
-
2005
- 2005-08-22 HK HK05107277.4A patent/HK1075037A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6828462B2 (en) | 2004-12-07 |
| GEP20053714B (en) | 2005-12-26 |
| PL370245A1 (en) | 2005-05-16 |
| JP2005508381A (ja) | 2005-03-31 |
| EA010177B1 (ru) | 2008-06-30 |
| KR100655975B1 (ko) | 2006-12-08 |
| KR20050044354A (ko) | 2005-05-12 |
| AU2002337389B2 (en) | 2005-12-08 |
| CO5570696A2 (es) | 2005-10-31 |
| CN1602292A (zh) | 2005-03-30 |
| WO2003040084A1 (en) | 2003-05-15 |
| MXPA04004412A (es) | 2005-05-16 |
| HK1075037A1 (en) | 2005-12-02 |
| HUP0402028A3 (en) | 2008-03-28 |
| US20030166634A1 (en) | 2003-09-04 |
| EP1442008A1 (en) | 2004-08-04 |
| IL161801A0 (en) | 2005-11-20 |
| HUP0402028A2 (hu) | 2005-01-28 |
| CA2465738A1 (en) | 2003-05-15 |
| EA200400637A1 (ru) | 2004-10-28 |
| CA2465738C (en) | 2009-01-20 |
| CN100390131C (zh) | 2008-05-28 |
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