AU2002337389B2 - Unsaturated 1-amino-alkylcyclohexane NMDA,5HT3 and neuronal nicotinic receptor antagonists - Google Patents

Unsaturated 1-amino-alkylcyclohexane NMDA,5HT3 and neuronal nicotinic receptor antagonists Download PDF

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Publication number
AU2002337389B2
AU2002337389B2 AU2002337389A AU2002337389A AU2002337389B2 AU 2002337389 B2 AU2002337389 B2 AU 2002337389B2 AU 2002337389 A AU2002337389 A AU 2002337389A AU 2002337389 A AU2002337389 A AU 2002337389A AU 2002337389 B2 AU2002337389 B2 AU 2002337389B2
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linear
branched lower
group
alleviation
alkenyl
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AU2002337389A1 (en
Inventor
Wojciech Dansyz
Markus Gold
Markus Henrich
Aigars Jirgensons
Ivars Kalvinsh
Valerjans Kauss
Christopher Graham Raphael Parsons
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Merz Pharma GmbH and Co KGaA
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Merz Pharma GmbH and Co KGaA
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    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
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    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
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AU2002337389A 2001-11-07 2002-11-07 Unsaturated 1-amino-alkylcyclohexane NMDA,5HT3 and neuronal nicotinic receptor antagonists Ceased AU2002337389B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35097401P 2001-11-07 2001-11-07
US60/350,974 2001-11-07
US33785801P 2001-11-08 2001-11-08
US60/337,858 2001-11-08
PCT/GB2002/005038 WO2003040084A1 (en) 2001-11-07 2002-11-07 Unsaturated 1-amino-alkylcyclohexane nmda, 5ht3 and neuronal nicotinic receptor antagonists

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AU2002337389A1 AU2002337389A1 (en) 2003-07-24
AU2002337389B2 true AU2002337389B2 (en) 2005-12-08

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AU2002337389A Ceased AU2002337389B2 (en) 2001-11-07 2002-11-07 Unsaturated 1-amino-alkylcyclohexane NMDA,5HT3 and neuronal nicotinic receptor antagonists

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US (1) US6828462B2 (enExample)
EP (1) EP1442008A1 (enExample)
JP (1) JP2005508381A (enExample)
KR (1) KR100655975B1 (enExample)
CN (1) CN100390131C (enExample)
AU (1) AU2002337389B2 (enExample)
CA (1) CA2465738C (enExample)
CO (1) CO5570696A2 (enExample)
EA (1) EA010177B1 (enExample)
GE (1) GEP20053714B (enExample)
HU (1) HUP0402028A3 (enExample)
IL (1) IL161801A0 (enExample)
MX (1) MXPA04004412A (enExample)
NO (1) NO20042338L (enExample)
PL (1) PL370245A1 (enExample)
WO (1) WO2003040084A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW593223B (en) * 2000-06-20 2004-06-21 Merz Pharma Gmbh & Co Kgaa 1-amino-alkylcyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists
AU2004258751C1 (en) * 2003-07-28 2008-07-17 Merz Pharma Gmbh & Co. Kgaa The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity
AR046314A1 (es) * 2003-11-05 2005-11-30 Merz Pharma Gmbh & Co Kgaa Composiciones que comprenden ciclohexilaminas y aminoadamantanos
TW200531680A (en) * 2004-03-03 2005-10-01 Merz Pharma Gmbh & Co Kgaa Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease
ES2483126T3 (es) * 2004-06-17 2014-08-05 Merz Pharma Gmbh & Co. Kgaa Formulaciones de formas de dosificación de neramexano
US7427601B2 (en) * 2004-06-24 2008-09-23 Schwarz Pharma Ag Method for treating tremor
US20060205822A1 (en) * 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
US7893289B2 (en) * 2007-02-21 2011-02-22 Ssv Therapeutics, Inc. Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids
EP2111858A1 (en) 2008-04-25 2009-10-28 EPFL Ecole Polytechnique Fédérale de Lausanne Novel treatment for alzheimer's disease
US20090275597A1 (en) * 2008-05-02 2009-11-05 Forest Laboratories Holdings Limited Methods of treating cns disorders
PE20110565A1 (es) 2008-08-12 2011-09-02 Zinfandel Pharmaceuticals Inc Metodo de identificacion de factores de riesgo de la enfermedad
US8846315B2 (en) 2008-08-12 2014-09-30 Zinfandel Pharmaceuticals, Inc. Disease risk factors and methods of use
EA201391017A1 (ru) 2011-01-10 2014-04-30 Зинфандел Фармасьютикалз, Инк. Способы и готовые лекарственные формы для лечения болезни альцгеймера
US20150182546A1 (en) * 2013-03-15 2015-07-02 Mitochondrial Concepts Llc Therapeutic agent for enhancing mitochondrial function
WO2018129609A1 (en) * 2017-01-10 2018-07-19 Owen-Barry Pharmaceuticals Inc. Anticonvulsant compounds
AU2024287244B1 (en) * 2024-12-28 2025-08-21 Lai, Meng Hong MR A device for relieving constipation and its preparation method

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Publication number Priority date Publication date Assignee Title
US4267366A (en) * 1977-12-14 1981-05-12 Scm Corporation Cyclic terpenoid amines, their preparation and uses
UA61962C2 (uk) * 1997-06-30 2003-12-15 Мерц Фарма Гмбх Унд Ко. Кгаа Сполука 1-аміноалкілциклогексану, фармацевтична композиція на її основі та спосіб лікування
US6071966A (en) 1997-06-30 2000-06-06 Merz + Co. Gmbh & Co. 1-amino-alkylcyclohexane NMDA receptor antagonists

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CA2465738C (en) 2009-01-20
JP2005508381A (ja) 2005-03-31
EA010177B1 (ru) 2008-06-30
WO2003040084A1 (en) 2003-05-15
PL370245A1 (en) 2005-05-16
HK1075037A1 (zh) 2005-12-02
IL161801A0 (en) 2005-11-20
GEP20053714B (en) 2005-12-26
CA2465738A1 (en) 2003-05-15
CO5570696A2 (es) 2005-10-31
HUP0402028A2 (hu) 2005-01-28
EA200400637A1 (ru) 2004-10-28
MXPA04004412A (es) 2005-05-16
US6828462B2 (en) 2004-12-07
US20030166634A1 (en) 2003-09-04
KR20050044354A (ko) 2005-05-12
KR100655975B1 (ko) 2006-12-08
HUP0402028A3 (en) 2008-03-28
CN100390131C (zh) 2008-05-28
EP1442008A1 (en) 2004-08-04
CN1602292A (zh) 2005-03-30
NO20042338L (no) 2004-07-21

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