MXPA03005388A - Peptido yy y agonistas de peptido yy para el tratamiento de desordenes metabolicos. - Google Patents
Peptido yy y agonistas de peptido yy para el tratamiento de desordenes metabolicos.Info
- Publication number
- MXPA03005388A MXPA03005388A MXPA03005388A MXPA03005388A MXPA03005388A MX PA03005388 A MXPA03005388 A MX PA03005388A MX PA03005388 A MXPA03005388 A MX PA03005388A MX PA03005388 A MXPA03005388 A MX PA03005388A MX PA03005388 A MXPA03005388 A MX PA03005388A
- Authority
- MX
- Mexico
- Prior art keywords
- peptide
- metabolic disorders
- agonists
- treatment
- pyy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2271—Neuropeptide Y
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Adhesive Tapes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25621600P | 2000-12-14 | 2000-12-14 | |
PCT/US2001/048336 WO2002047712A2 (en) | 2000-12-14 | 2001-12-14 | Peptide yy and peptide yy agonists for treatment of metabolic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03005388A true MXPA03005388A (es) | 2003-09-25 |
Family
ID=22971453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03005388A MXPA03005388A (es) | 2000-12-14 | 2001-12-14 | Peptido yy y agonistas de peptido yy para el tratamiento de desordenes metabolicos. |
Country Status (12)
Country | Link |
---|---|
US (3) | US8273713B2 (es) |
EP (2) | EP1349563B1 (es) |
JP (1) | JP2004515533A (es) |
CN (1) | CN1568195B (es) |
AT (1) | ATE450269T1 (es) |
AU (1) | AU2002230843B8 (es) |
BR (1) | BR0116206A (es) |
CA (1) | CA2431800C (es) |
DE (1) | DE60140693D1 (es) |
MX (1) | MXPA03005388A (es) |
RU (1) | RU2275207C2 (es) |
WO (1) | WO2002047712A2 (es) |
Families Citing this family (87)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
AU2002353784B2 (en) * | 2001-09-24 | 2008-04-10 | Oregon Health And Science University | Assessment of neurons in the arcuate nucleus to screen for agents that modify feeding behavior |
IL160983A0 (en) * | 2001-09-24 | 2004-08-31 | Imp College Innovations Ltd | Use of pyy for preparation of a medicament for modification of feeding behavior |
US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
AU2003201998C1 (en) * | 2002-01-10 | 2012-10-25 | Imperial Innovations Limited | Modification of feeding behavior |
JP2006516262A (ja) | 2002-12-17 | 2006-06-29 | ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド | Y2受容体結合ペプチドの粘膜送達促進のための組成物および方法ならびに肥満症の治療法および予防法 |
US7186692B2 (en) | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
US7229966B2 (en) | 2002-12-17 | 2007-06-12 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
GB0300571D0 (en) | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
US7811989B2 (en) | 2003-01-17 | 2010-10-12 | Ipsen Pharma S.A.S. | Peptide YY analogs |
WO2004089280A2 (en) | 2003-04-08 | 2004-10-21 | Yeda Research And Development Co. Ltd. | Reversible pegylated drugs |
WO2005000222A2 (en) | 2003-05-30 | 2005-01-06 | Amylin Pharmaceuticals, Inc. | Novel methods and compositions for enhanced transmucosal delivery of peptides and proteins |
EP1689421A4 (en) * | 2003-11-25 | 2009-06-24 | Bayer Healthcare Ag | SELECTIVE AGONISTS OF NEUROPEPTIDE Y2 RECEPTOR |
US7649002B2 (en) | 2004-02-04 | 2010-01-19 | Pfizer Inc | (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists |
CN103897066A (zh) * | 2004-02-11 | 2014-07-02 | 安米林药品有限责任公司 | 具有可选择特性的杂合多肽 |
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
CA2555894A1 (en) * | 2004-02-11 | 2005-08-25 | Amylin Pharmaceuticals, Inc. | Pancreatic polypeptide family motifs and polypeptides comprising the same |
EA011860B1 (ru) * | 2004-03-17 | 2009-06-30 | 7ТиЭм ФАРМА А/С | Селективные агонисты рецептора y2 для терапевтического воздействия |
CN1953763A (zh) * | 2004-03-17 | 2007-04-25 | 7Tm制药联合股份有限公司 | 用于治疗性干预的y4选择性受体激动剂 |
JP2007531714A (ja) * | 2004-03-17 | 2007-11-08 | 7ティーエム ファーマ エイ/エス | 治療的介入のためのy2/y4選択性レセプターアゴニスト |
NZ551196A (en) | 2004-05-14 | 2010-08-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents |
NZ551241A (en) * | 2004-05-14 | 2010-08-27 | Emisphere Tech Inc | Aryl ketone compounds and compositions for delivering active agents |
WO2005110457A2 (en) * | 2004-05-18 | 2005-11-24 | Aditech Pharma Ab | Treatment of eating disorders and induction of lipolysis |
US20090069226A1 (en) * | 2004-05-28 | 2009-03-12 | Amylin Pharmaceuticals, Inc. | Transmucosal delivery of peptides and proteins |
JP5749879B2 (ja) * | 2004-07-12 | 2015-07-15 | エミスフェアー・テクノロジーズ・インク | ペプチドyyおよびペプチドyyアゴニストの送達用組成物 |
EP1645877A1 (en) * | 2004-10-08 | 2006-04-12 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Method for providing a insulin resistance biomarker profile of one or more lipids |
ES2325773T5 (es) | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals, Llc. | Tratamiento de la obesidad y de los trastornos relacionados |
BRPI0518559A2 (pt) | 2004-12-13 | 2008-11-25 | Amylin Pharmaceuticals Inc | motivos da famÍlia do polipetÍdeo pancreÁtico, polipeptÍdeos e mÉtodos compreendendo os mesmos |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2007022123A2 (en) | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
EP1888043A4 (en) * | 2005-03-11 | 2010-07-28 | Endo Pharmaceuticals Solutions | OCTREOTIDE FORMULATIONS WITH CONTROLLED RELEASE |
US7759312B2 (en) * | 2005-03-11 | 2010-07-20 | Endo Pharmaceuticals Solutions Inc. | Delivery of dry formulations of octreotide |
GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
EP2330125A3 (en) * | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
EP1934254A1 (en) | 2005-09-21 | 2008-06-25 | 7TM Pharma A/S | Y4 selective receptor agonists for therapeutic interventions |
JP2009508886A (ja) | 2005-09-21 | 2009-03-05 | 7ティーエム ファーマ エイ/エス | 治療的介入のためのy2選択性レセプターアゴニスト |
US20070232537A1 (en) * | 2005-12-19 | 2007-10-04 | Nastech Pharmaceutical Company Inc. | Intranasal pyy formulations with improved transmucosal pharmacokinetics |
CA2642922C (en) | 2006-02-23 | 2011-08-02 | Pfizer Limited | Melanocortin type 4 receptor agonist piperidinoylpyrrolidines |
WO2007112069A2 (en) * | 2006-03-23 | 2007-10-04 | Amylin Pharmaceuticals, Inc. | Endothelin and endothelin receptor agonists in the treatment of metabolic diseases |
ES2351527T3 (es) | 2006-05-30 | 2011-02-07 | Intarcia Therapeutics, Inc | Modulador de flujo en dos piezas con conducto interno para un sistema osmótico de administración. |
EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
CN101583593A (zh) | 2006-11-13 | 2009-11-18 | 辉瑞产品公司 | 二芳基、二吡啶基和芳基-吡啶基衍生物及其用途 |
EP2099755A2 (en) * | 2006-11-20 | 2009-09-16 | Glenmark Pharmaceuticals S.A. | Acetylene derivatives as stearoyl coa desaturase inhibitors |
TWI428346B (zh) * | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
EP2157967B1 (en) | 2007-04-23 | 2013-01-16 | Intarcia Therapeutics, Inc | Suspension formulations of insulinotropic peptides and uses thereof |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EA020466B1 (ru) | 2007-06-04 | 2014-11-28 | Синерджи Фармасьютикалз Инк. | Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний |
WO2009037542A2 (en) | 2007-09-20 | 2009-03-26 | Glenmark Pharmaceuticals, S.A. | Spirocyclic compounds as stearoyl coa desaturase inhibitors |
CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
CA2723855A1 (en) * | 2008-05-16 | 2009-11-19 | Novo Nordisk A/S | Long-acting y2 and/or y4 receptor agonists |
CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
UA104866C2 (uk) | 2008-06-25 | 2014-03-25 | Ендо Фармас'Ютікалз Солюшнз Інк. | Імплантат октреотиду, який містить вивільняючу речовину |
JP5622725B2 (ja) * | 2008-06-25 | 2014-11-12 | エンド ファーマスーティカルズ ソリューションズ インコーポレイテッド.Endo Pharmaceuticals Solutionsinc. | エキセナチド及び他のポリペプチド類の持続的送達 |
CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
MX2011001405A (es) | 2008-08-06 | 2011-03-21 | Pfizer Ltd | Compuestos de diazepina y diazocano como agonistas de mc4. |
US9492505B2 (en) | 2009-01-21 | 2016-11-15 | University Of Florida Research Foundation, Inc. | Satiation peptide administration |
EP3323423B1 (en) | 2009-09-28 | 2020-06-17 | Intarcia Therapeutics, Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
WO2011133948A2 (en) | 2010-04-22 | 2011-10-27 | Longevity Biotech, Inc. | Highly active polypeptides and methods of making and using the same |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP5902194B2 (ja) | 2010-12-16 | 2016-04-13 | ノヴォ ノルディスク アー/エス | Glp−1アゴニストとn−(8−(2−ヒドロキシベンゾイル)アミノ)カプリル酸の塩とを含む固形組成物 |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
WO2012125622A1 (en) | 2011-03-14 | 2012-09-20 | Bristol-Myers Squibb Company | Substituted adipic acid amides and uses thereof |
US10166295B2 (en) | 2011-06-02 | 2019-01-01 | Opko Biologics Ltd. | Pegylated OXM variants |
ES2952874T3 (es) | 2012-03-22 | 2023-11-06 | Novo Nordisk As | Composiciones de péptidos GLP-1 y preparación de estas |
CN109096387B (zh) | 2012-06-04 | 2021-11-30 | 奥普科生物制品有限公司 | 聚乙二醇化的oxm变体 |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
WO2014145718A2 (en) | 2013-03-15 | 2014-09-18 | Longevity Biotech, Inc. | Peptides comprising non-natural amino acids and methods of making and using the same |
CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
CN113388007A (zh) | 2013-06-05 | 2021-09-14 | 博士医疗爱尔兰有限公司 | 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法 |
MX369818B (es) * | 2013-11-15 | 2019-11-22 | Novo Nordisk As | Compuestos selectivos de peptido yy (pyy) y usos de los mismos. |
JP6629198B2 (ja) | 2013-11-15 | 2020-01-15 | ノヴォ ノルディスク アー/エス | 35位にβ−ホモアルギニン置換を有するHPYY(1−36) |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
MA44390A (fr) | 2015-06-03 | 2019-01-23 | Intarcia Therapeutics Inc | Systèmes de mise en place et de retrait d'implant |
AR104984A1 (es) | 2015-06-12 | 2017-08-30 | Novo Nordisk As | Compuestos selectivos para pyy y sus usos |
US10224727B2 (en) * | 2015-06-30 | 2019-03-05 | Dong-Sheng Li | Multi-functional hub integrated with AC power supply |
US11311633B2 (en) | 2016-04-16 | 2022-04-26 | University Of Florida Research Foundation, Incorporated | Satiation peptides for weight loss and altered taste sensitivity |
SG11201810102SA (en) | 2016-05-16 | 2018-12-28 | Intarcia Therapeutics Inc | Glucagon-receptor selective polypeptides and methods of use thereof |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
BR112020014596A2 (pt) | 2018-01-23 | 2020-12-08 | Gila Therapeutics, Inc. | Formulações, composições e métodos farmacêuticos de peptídeo yy |
JP6898518B2 (ja) | 2018-02-02 | 2021-07-07 | ノヴォ ノルディスク アー/エス | Glp−1アゴニスト、n−(8−(2−ヒドロキシベンゾイル)アミノ)カプリル酸の塩及び滑沢剤を含む固形組成物 |
GB2573145A (en) * | 2018-04-26 | 2019-10-30 | Univ Ulster | Peptides for metabolic disease |
TWI749381B (zh) | 2018-11-01 | 2021-12-11 | 美商美國禮來大藥廠 | 蛋白質酪胺酸-酪胺酸類似物及其使用方法 |
Family Cites Families (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
US4701441A (en) * | 1985-02-11 | 1987-10-20 | University Of Florida | Methods and compositions for stimulation of appetite |
US4891357A (en) | 1985-02-11 | 1990-01-02 | University Of Florida | Methods and compositions for stimulation of appetite |
US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4839343A (en) * | 1987-03-13 | 1989-06-13 | Debiopharm, S.A. | Preparation containing hexatriacontapeptides and methods of use |
WO1989001967A1 (en) | 1987-09-03 | 1989-03-09 | Brown University Research Foundation | Blood purification with cultured renal cells |
US4892538A (en) * | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
US5158881A (en) | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
US5011472A (en) | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
WO1990006952A1 (en) * | 1988-12-22 | 1990-06-28 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
US5459039A (en) * | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
DK0478671T3 (da) | 1989-06-21 | 1993-10-18 | Univ Brown Res Found | Neurologisk terapeutisk anordning |
WO1991010470A1 (en) | 1990-01-08 | 1991-07-25 | Brown University Research Foundation | Devices and methods for enhanced delivery of active factors |
US6391343B1 (en) * | 1991-01-15 | 2002-05-21 | Hemosphere, Inc. | Fibrinogen-coated particles for therapeutic use |
HU222249B1 (hu) | 1991-03-08 | 2003-05-28 | Amylin Pharmaceuticals Inc. | Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
US5547835A (en) | 1993-01-07 | 1996-08-20 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
NZ265452A (en) | 1993-03-29 | 1997-09-22 | Univ Cincinnati | Analogues of peptide yy, dimers and pharmaceutical compositions |
US5498531A (en) * | 1993-09-10 | 1996-03-12 | President And Fellows Of Harvard College | Intron-mediated recombinant techniques and reagents |
US5545549A (en) * | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
US5696093A (en) * | 1994-10-28 | 1997-12-09 | Crc For Biopharmaceutical Research Pty Limited | Method of treating nasal congestion using neuropeptide Y Y2 agonist peptides |
US5574010A (en) * | 1994-11-14 | 1996-11-12 | The Regents Of The University Of California | Treatment of pancreatic tumors with peptide YY and analogs thereof |
US5602024A (en) | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
US5912227A (en) | 1995-01-27 | 1999-06-15 | North Carolina State University | Method of enhancing nutrient uptake |
US6558708B1 (en) * | 1995-05-17 | 2003-05-06 | Cedars-Sinai Medical Center | Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia |
US20020094346A1 (en) * | 1995-05-17 | 2002-07-18 | M. D. Henry C. Lin | Method and compositions for improving digestion and absorption in the small intestine |
US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
US6355478B1 (en) * | 1996-06-17 | 2002-03-12 | Eli Lilly And Company | Rhesus monkey neuropeptide Y Y2 receptor |
US5686511A (en) | 1996-06-28 | 1997-11-11 | The Valspar Corporation | Esterifying epoxy resin with carboxyl polymer and quenching |
WO1998030231A1 (en) | 1997-01-07 | 1998-07-16 | Amylin Pharmaceuticals, Inc. | Use of exendins and agonists thereof for the reduction of food intake |
EP0910565A1 (en) | 1997-02-14 | 1999-04-28 | Bayer Corporation | Amide derivatives as selective neuropeptide y receptor antagonists |
DE69812096T2 (de) * | 1997-04-23 | 2003-10-30 | Banyu Pharma Co Ltd | Neuropeptid y rezeptorantagonisten |
ES2293688T5 (es) | 1997-08-08 | 2011-05-04 | Amylin Pharmaceuticals, Inc. | Nuevos compuestos análogos de la exendina. |
JP3036480B2 (ja) * | 1997-08-25 | 2000-04-24 | 日本電気株式会社 | バーコード読取装置およびその焦点制御方法 |
AU9185598A (en) | 1997-09-25 | 1999-04-12 | Banyu Pharmaceutical Co., Ltd. | Novel neuropeptide y receptor antagonists |
EP1032587B2 (en) | 1997-11-14 | 2013-03-13 | Amylin Pharmaceuticals, Inc. | Novel exendin agonist compounds |
JP2003522721A (ja) | 1997-11-14 | 2003-07-29 | アミリン・ファーマシューティカルズ,インコーポレイテッド | 新規なエキセンジンアゴニスト化合物 |
CA2320962C (en) | 1998-02-13 | 2011-04-19 | Amylin Pharmaceuticals, Inc. | Novel mixed amylin activity compounds |
US6013622A (en) | 1998-04-15 | 2000-01-11 | Nutriceutical Technology Corporation | Method of regulating appetite and metabolism |
EP1100530B1 (en) * | 1998-07-31 | 2003-10-08 | Novo Nordisk A/S | In-vitro stimulation of beta cell proliferation |
US20020015950A1 (en) * | 1999-07-07 | 2002-02-07 | Karen Anne Jones | Atherosclerosis-associated genes |
ES2353728T3 (es) * | 1999-02-10 | 2011-03-04 | Curis, Inc. | Péptido yy (pyy) para tratar trastornos metabólicos de la glucosa. |
US7745216B2 (en) * | 1999-02-10 | 2010-06-29 | Curis, Inc. | Methods and reagents for treating glucose metabolic disorders |
MXPA01011321A (es) * | 1999-05-05 | 2003-08-01 | Johnson & Johnson | Neuropeptidos y ligandos de receptores 3a, 4, 5, 9b-tetrahidro-1h-benz(e)indol-2-il amino derivados utiles en el tratamiento de obesidad y otros trastornos. |
US6569832B1 (en) * | 1999-11-12 | 2003-05-27 | Novo Nordisk A/S | Inhibition of beta cell degeneration |
US6734166B1 (en) * | 2000-02-08 | 2004-05-11 | North Carolina State University | Method of reducing aluminum levels in the central nervous system |
US6531478B2 (en) * | 2000-02-24 | 2003-03-11 | Cheryl P. Kordik | Amino pyrazole derivatives useful for the treatment of obesity and other disorders |
IL160983A0 (en) | 2001-09-24 | 2004-08-31 | Imp College Innovations Ltd | Use of pyy for preparation of a medicament for modification of feeding behavior |
AU2003201998C1 (en) | 2002-01-10 | 2012-10-25 | Imperial Innovations Limited | Modification of feeding behavior |
US20060122106A1 (en) | 2002-06-14 | 2006-06-08 | Amylin Pharmaceuticals, Inc | Prevention and/or treatment of inflammatory bowel disease using pyy or agonists thereof |
-
2001
- 2001-12-14 JP JP2002549282A patent/JP2004515533A/ja active Pending
- 2001-12-14 CN CN018226477A patent/CN1568195B/zh not_active Expired - Fee Related
- 2001-12-14 EP EP01991093A patent/EP1349563B1/en not_active Revoked
- 2001-12-14 DE DE60140693T patent/DE60140693D1/de not_active Expired - Lifetime
- 2001-12-14 RU RU2003121230/15A patent/RU2275207C2/ru not_active IP Right Cessation
- 2001-12-14 CA CA2431800A patent/CA2431800C/en not_active Expired - Fee Related
- 2001-12-14 WO PCT/US2001/048336 patent/WO2002047712A2/en active Application Filing
- 2001-12-14 EP EP09010965A patent/EP2123293A3/en not_active Withdrawn
- 2001-12-14 AU AU2002230843A patent/AU2002230843B8/en not_active Ceased
- 2001-12-14 US US10/016,969 patent/US8273713B2/en not_active Expired - Fee Related
- 2001-12-14 MX MXPA03005388A patent/MXPA03005388A/es active IP Right Grant
- 2001-12-14 BR BR0116206-3A patent/BR0116206A/pt not_active Application Discontinuation
- 2001-12-14 AT AT01991093T patent/ATE450269T1/de not_active IP Right Cessation
-
2012
- 2012-09-14 US US13/618,265 patent/US20130023466A1/en not_active Abandoned
-
2014
- 2014-01-24 US US14/163,689 patent/US20140135261A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE450269T1 (de) | 2009-12-15 |
US20140135261A1 (en) | 2014-05-15 |
CA2431800A1 (en) | 2002-06-20 |
BR0116206A (pt) | 2003-12-23 |
JP2004515533A (ja) | 2004-05-27 |
AU3084302A (en) | 2002-06-24 |
EP2123293A3 (en) | 2010-09-08 |
AU2002230843B2 (en) | 2006-10-19 |
EP1349563A2 (en) | 2003-10-08 |
US20130023466A1 (en) | 2013-01-24 |
EP1349563B1 (en) | 2009-12-02 |
DE60140693D1 (en) | 2010-01-14 |
RU2275207C2 (ru) | 2006-04-27 |
US8273713B2 (en) | 2012-09-25 |
CN1568195A (zh) | 2005-01-19 |
EP2123293A2 (en) | 2009-11-25 |
CN1568195B (zh) | 2011-03-02 |
WO2002047712A3 (en) | 2002-09-06 |
US20020141985A1 (en) | 2002-10-03 |
WO2002047712A2 (en) | 2002-06-20 |
AU2002230843B8 (en) | 2007-05-17 |
CA2431800C (en) | 2014-07-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU3084302A (en) | Peptide yy and peptide yy agonists for treatment of metabolic disorders | |
IL267381A (en) | A pharmaceutical preparation containing dextromethorphan and quinidine for the treatment of nervous disorders | |
WO2003057666A3 (en) | Inhibitors of dipeptidyl peptidase iv | |
IL160983A (en) | Use of pyy for preparation of a medicament for modification of feeding behavior | |
AP2001002129A0 (en) | 5HT1 receptor agonists and metoclopramide for the treatment of migrane. | |
DE60128912D1 (en) | Pyridoxin- und pyridoxalanaloga als cardiovasculäre therapeutika | |
WO2004091540A3 (en) | Methods of treating pain and compositions for use therefor | |
TWI367751B (en) | Pharmaceutical composition comprising rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction | |
WO2006002096A3 (en) | Low doses of l-citrulline for treating diseases | |
MY118526A (en) | Method for improving the pharmacokinetics of tipranavir | |
BR0316723A (pt) | Derivados de anilinopirazol úteis para o tratamento de diabetes | |
HK1073250A1 (en) | Use of pleuromutilins for the treatment of disorders caused by helicobacter pylori | |
EP1108426A3 (en) | Use of prostaglandin agonists to treat erectile dysfunction or impotence | |
WO2002064160A8 (en) | Pharmaceutical compositions which inhibit vascular proliferation and method of use thereof | |
WO2003049667A3 (en) | The method of treating cancer | |
IL126159A (en) | Pharmaceutical composition containing duloxetine for treating or preventing interstitial cystitis | |
WO2003084503A3 (en) | P38 kinase inhibitors for treating mucus hypersecretion_ | |
EP1546377A4 (en) | METHODS AND COMPOSITIONS FOR TREATING PAIN AND PAIN DISORDERS USING MOLECULES 9949, 14230, 760, 62553, 41897, 47174, 33408, 10002, 16209, 314, 636, 27410, 33260, 619, 15985, 69112, 2158, 224, 615, 44373, 95431, 22245, 2387, 16658, 55054, 9569 OR 13424 | |
MXPA01007952A (es) | Formulaciones a base de l-arginina para tratar enfermedades, y metodos para usarlas. | |
ZA200209714B (en) | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV. | |
WO2002038144A8 (en) | The use of tiagabine for treatment of diabetic neuropathy and migraine | |
EP1260221A3 (en) | Combination treatment for depression and anxiety | |
WO2003003983A3 (en) | Receptor agonists useful for the treatment of pain | |
TW200512183A (en) | 2-alkylidene-19-nor-vitamin d derivatives for the treatment of frailty, muscle damage or sarcopenia | |
AU2002357691A1 (en) | Methods and compositions to treat pain and painful disorders using 577, 20739 or 57145 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
GB | Transfer or rights | ||
HC | Change of company name or juridical status |