MXPA03002788A - Moduladores de receptor c5a de molecula pequena de alta afinidad. - Google Patents

Moduladores de receptor c5a de molecula pequena de alta afinidad.

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Publication number
MXPA03002788A
MXPA03002788A MXPA03002788A MXPA03002788A MXPA03002788A MX PA03002788 A MXPA03002788 A MX PA03002788A MX PA03002788 A MXPA03002788 A MX PA03002788A MX PA03002788 A MXPA03002788 A MX PA03002788A MX PA03002788 A MXPA03002788 A MX PA03002788A
Authority
MX
Mexico
Prior art keywords
alkyl
amino
mono
alkoxy
optionally substituted
Prior art date
Application number
MXPA03002788A
Other languages
English (en)
Spanish (es)
Inventor
Xiaoyan Zhang
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of MXPA03002788A publication Critical patent/MXPA03002788A/es

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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MXPA03002788A 2000-09-29 2000-09-29 Moduladores de receptor c5a de molecula pequena de alta afinidad. MXPA03002788A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/026816 WO2002049993A2 (en) 2000-09-29 2000-09-29 High affinity small molecule c5a receptor modulators

Publications (1)

Publication Number Publication Date
MXPA03002788A true MXPA03002788A (es) 2004-12-13

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MXPA03002788A MXPA03002788A (es) 2000-09-29 2000-09-29 Moduladores de receptor c5a de molecula pequena de alta afinidad.

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EP (1) EP1322309B1 (https=)
JP (1) JP5260818B2 (https=)
KR (1) KR20030060887A (https=)
CN (1) CN1454086A (https=)
AT (1) ATE404553T1 (https=)
AU (1) AU7622500A (https=)
BR (1) BR0017338A (https=)
DE (1) DE60039921D1 (https=)
IL (1) IL154993A0 (https=)
MX (1) MXPA03002788A (https=)
NO (1) NO20031370L (https=)
WO (1) WO2002049993A2 (https=)
YU (1) YU23503A (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PA8535601A1 (es) 2000-12-21 2002-11-28 Pfizer Derivados benzimidazol y piridilimidazol como ligandos para gabaa
CA2479930A1 (en) * 2002-03-28 2003-10-09 Neurogen Corporation Substituted tetrahydroisoquinolines as c5a receptor modulators
US6858637B2 (en) 2002-03-28 2005-02-22 Neurogen Corporation Substituted biaryl amides as C5a receptor modulators
EP1487796A4 (en) * 2002-03-28 2005-11-16 Neurogen Corp SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR
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