MXPA03001389A - Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu. - Google Patents

Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu.

Info

Publication number
MXPA03001389A
MXPA03001389A MXPA03001389A MXPA03001389A MXPA03001389A MX PA03001389 A MXPA03001389 A MX PA03001389A MX PA03001389 A MXPA03001389 A MX PA03001389A MX PA03001389 A MXPA03001389 A MX PA03001389A MX PA03001389 A MXPA03001389 A MX PA03001389A
Authority
MX
Mexico
Prior art keywords
neu
compositions
diagnosis
polypeptides
therapy
Prior art date
Application number
MXPA03001389A
Other languages
English (en)
Inventor
Martin A Cheever
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of MXPA03001389A publication Critical patent/MXPA03001389A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/463—Cellular immunotherapy characterised by recombinant expression
    • A61K39/4632—T-cell receptors [TCR]; antibody T-cell receptor constructs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464402—Receptors, cell surface antigens or cell surface determinants
    • A61K39/464403—Receptors for growth factors
    • A61K39/464406—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Abstract

Se describen composiciones y metodos para la terapia y el diagnostico de cancer, particularmente canceres asociados con Her-2/neu. Las composiciones ilustrativas comprenden uno o mas polipeptidos Her-2/neu, sus porciones inmunogenicas, polinucleotidos que codifican dichos polipeptidos, celulas de presentacion de antigeno que expresan dichos polipeptidos, y celulas T que son especificas para celulas que expresan dichos polipeptidos. Las composiciones descritas son utiles en, por ejemplo, el diagnostica, la prevencion y/o el tratamiento de malignidades asociadas con Her-2/neun.
MXPA03001389A 2000-08-14 2001-08-14 Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu. MXPA03001389A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22515200P 2000-08-14 2000-08-14
US23642800P 2000-09-28 2000-09-28
US27052001P 2001-02-21 2001-02-21
PCT/US2001/041733 WO2002014503A2 (en) 2000-08-14 2001-08-14 Compositions and methods for the therapy and diagnosis of her-2/neu-associated malignancies

Publications (1)

Publication Number Publication Date
MXPA03001389A true MXPA03001389A (es) 2004-05-04

Family

ID=27397445

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03001389A MXPA03001389A (es) 2000-08-14 2001-08-14 Composiciones y metodos para la terapia y diagnostico de malignidades asociadas con her-2/neu.

Country Status (14)

Country Link
US (1) US20020193329A1 (es)
EP (1) EP1366153A2 (es)
JP (1) JP2004522412A (es)
KR (1) KR20030048009A (es)
CN (1) CN1537164A (es)
AU (1) AU2001295008A1 (es)
BR (1) BR0113235A (es)
CA (1) CA2419533A1 (es)
HU (1) HUP0600780A2 (es)
IL (1) IL154415A0 (es)
MX (1) MXPA03001389A (es)
NO (1) NO20030714L (es)
PL (1) PL365789A1 (es)
WO (1) WO2002014503A2 (es)

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Also Published As

Publication number Publication date
AU2001295008A1 (en) 2002-02-25
EP1366153A2 (en) 2003-12-03
NO20030714L (no) 2003-04-11
IL154415A0 (en) 2003-09-17
WO2002014503A2 (en) 2002-02-21
NO20030714D0 (no) 2003-02-14
CN1537164A (zh) 2004-10-13
KR20030048009A (ko) 2003-06-18
PL365789A1 (en) 2005-01-10
CA2419533A1 (en) 2002-02-21
JP2004522412A (ja) 2004-07-29
WO2002014503A3 (en) 2003-09-18
US20020193329A1 (en) 2002-12-19
BR0113235A (pt) 2004-06-08
HUP0600780A2 (en) 2007-01-29

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