EP1064022A4 - Hla-binding peptides and their uses - Google Patents

Hla-binding peptides and their uses

Info

Publication number
EP1064022A4
EP1064022A4 EP98910404A EP98910404A EP1064022A4 EP 1064022 A4 EP1064022 A4 EP 1064022A4 EP 98910404 A EP98910404 A EP 98910404A EP 98910404 A EP98910404 A EP 98910404A EP 1064022 A4 EP1064022 A4 EP 1064022A4
Authority
EP
European Patent Office
Prior art keywords
hla
binding peptides
peptides
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98910404A
Other languages
German (de)
French (fr)
Other versions
EP1064022A1 (en
Inventor
Alessandro Sette
Ralph T Kubo
John Sidney
Esteban Celis
Howard M Grey
Scott Southwood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Epimmune Inc
Original Assignee
Epimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epimmune Inc filed Critical Epimmune Inc
Publication of EP1064022A1 publication Critical patent/EP1064022A1/en
Publication of EP1064022A4 publication Critical patent/EP1064022A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP98910404A 1998-03-13 1998-03-13 Hla-binding peptides and their uses Withdrawn EP1064022A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/005039 WO1999045954A1 (en) 1998-03-13 1998-03-13 Hla-binding peptides and their uses

Publications (2)

Publication Number Publication Date
EP1064022A1 EP1064022A1 (en) 2001-01-03
EP1064022A4 true EP1064022A4 (en) 2004-09-29

Family

ID=22266589

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98910404A Withdrawn EP1064022A4 (en) 1998-03-13 1998-03-13 Hla-binding peptides and their uses

Country Status (5)

Country Link
EP (1) EP1064022A4 (en)
JP (1) JP2002507397A (en)
AU (1) AU6465598A (en)
CA (1) CA2323632A1 (en)
WO (1) WO1999045954A1 (en)

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US9340577B2 (en) 1992-08-07 2016-05-17 Epimmune Inc. HLA binding motifs and peptides and their uses
US6291430B1 (en) 1997-09-12 2001-09-18 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
US6716809B1 (en) 1997-09-12 2004-04-06 Ludwig Institute For Cancer Research Mage-A3 peptides presented by HLA class molecules
US6183746B1 (en) 1997-10-09 2001-02-06 Zycos Inc. Immunogenic peptides from the HPV E7 protein
EP1117679B9 (en) * 1998-10-02 2010-07-07 Ludwig Institute For Cancer Research Tumor antigens and ctl clones isolated by a novel procedure
US6407063B1 (en) 1998-10-02 2002-06-18 Ludwig Institute For Cancer Research Tumor antigens and CTL clones isolated by a novel procedure
US6541214B1 (en) * 1998-11-13 2003-04-01 Oregon Heath Science University N-terminally truncated HER-2/neu protein as a cancer prognostic indicator
GB9826143D0 (en) 1998-11-27 1999-01-20 Ludwig Inst Cancer Res Tumour rejection antigens
NZ512052A (en) * 1998-12-01 2003-10-31 Sumitomo Pharma Novel tumor antigen protein art-1 and tumor antigen peptide thereof
IT1309584B1 (en) * 1999-02-26 2002-01-24 San Raffaele Centro Fond IMMUNOGENIC PEPTIDES DERIVED FROM MAGE-3 PRESENTED BY MHC OF CLASS II AND THEIR USE.
WO2001032193A1 (en) * 1999-10-29 2001-05-10 Argonex Pharmaceuticals Cytotoxic t lymphocyte-stimulating peptides for prevention, treatment, and diagnosis of melanoma
ATE445643T1 (en) * 1999-11-18 2009-10-15 Pharmexa Inc HETEROCLITIC ANALOGUE OF CLASS-I EPITOPES
CA2393339A1 (en) * 1999-12-10 2001-06-14 Epimmune Inc. Inducing cellular immune responses to mage2/3 using peptide and nucleic acid compositions
AU2088701A (en) * 1999-12-10 2001-06-18 Epimmune, Inc. Inducing cellular immune responses to p53 using peptide and nucleic acid compositions
CA2393738A1 (en) * 1999-12-10 2001-06-14 Epimmune Inc. Inducing cellular immune responses to her2/neu using peptide and nucleic acid compositions
US7026443B1 (en) 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
US20040037843A1 (en) * 1999-12-21 2004-02-26 John Fikes Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions
US7462354B2 (en) 1999-12-28 2008-12-09 Pharmexa Inc. Method and system for optimizing minigenes and peptides encoded thereby
FR2806727A1 (en) * 2000-03-23 2001-09-28 Pf Medicament MOLECULE OF PHARMACEUTICAL INTEREST COMPRISING IN THE N-TERMINAL END A GLUTAMIC ACID OR GLUTAMINE IN THE FORM OF A PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALT
WO2001074847A2 (en) * 2000-03-30 2001-10-11 The Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services T-cell epitope of mage-12 and related nucleic acids, vectors, cells, compositions and methods of inducing an immune response to cancer
CN1107681C (en) * 2000-08-11 2003-05-07 中国科学院微生物研究所 Compound of polypeptide as antigen of hepatitis B virus and heat shock protein and its application
MXPA03001389A (en) * 2000-08-14 2004-05-04 Corixa Corp Compositions and methods for the therapy and diagnosis of her-2/neu-associated malignancies.
JP2004508340A (en) * 2000-09-01 2004-03-18 エピミューン　インコーポレーティッド HLA binding peptides and methods of use
EP1195381A1 (en) * 2000-09-28 2002-04-10 Immusystems GmbH Hepatitis c virus epitopes specific for cd4+ t-cell lymphocytes
AU3941002A (en) 2000-10-31 2002-06-03 Zycos Inc Cyp1b1 nucleic acids and methods of use
JP2004535369A (en) * 2001-03-01 2004-11-25 アメリカ合衆国 Immunogenic HIV peptides for use as reagents and vaccines
CN100589845C (en) * 2001-03-07 2010-02-17 麦康公司 Anti-neovasculature preparations for cancer
EP1752160A3 (en) * 2001-04-06 2007-05-30 Mannkind Corporation Epitope sequences
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
WO2002080848A2 (en) 2001-04-09 2002-10-17 Mayo Foundation For Medical Education And Research Methods and materials for cancer treatment
US7049413B2 (en) 2001-05-18 2006-05-23 Ludwig Institute For Cancer Research MAGE-A3 peptides presented by HLA class II molecules
WO2002094994A2 (en) 2001-05-18 2002-11-28 Mayo Foundation For Medical Education And Research Chimeric antigen-specific t cell-activating polypeptides
US20060222656A1 (en) 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
US7223836B2 (en) 2001-06-05 2007-05-29 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Peptides for chlamydophila pneumoniae vaccine and diagnosis
US20030113919A1 (en) * 2001-08-17 2003-06-19 Aventis Pasteur, Ltd. Immunogenic targets for melanoma
CA2357906A1 (en) * 2001-09-28 2003-03-28 Institut Pasteur Identification of new cd8 epitopes from hiv-1 proteins with therapeutical and vaccinal properties against hiv infections
DE60238864D1 (en) * 2001-11-07 2011-02-17 Mankind Corp FOR EPITOPES OF ANTIGENIC ENCODING EXPRESSION VECTORS AND METHOD FOR THEIR DESIGN
AU2002349543A1 (en) * 2001-12-10 2003-06-23 Kyogo Itoh Tumor antigens
EP1495322A4 (en) * 2002-04-05 2006-09-06 Epimmune Inc Heteroclitic analogs and related methods
EP2336189A1 (en) * 2003-01-28 2011-06-22 Proscan RX Pharma Prostate cancer diagnosis and treatment
WO2005007694A1 (en) * 2003-07-16 2005-01-27 Green Peptide Co., Ltd. HER2/neu PEPTIDE AND THERAPEUTIC USE TEHREOF
EP2481422A3 (en) * 2003-09-03 2013-04-03 Dendritherapeutics, Inc. Multiplex vaccines
US7488793B2 (en) * 2003-09-22 2009-02-10 Ludwig Institute For Cancer Research Isolated peptide which binds to HLA-Cw*07 and uses thereof
KR20060087574A (en) * 2003-09-22 2006-08-02 가부시키가이샤 그린 펩티드 Peptide originating in hepatitis c virus
US9090673B2 (en) 2003-12-12 2015-07-28 City Of Hope Synthetic conjugate of CpG DNA and T-help/CTL peptide
GB0716992D0 (en) 2007-08-31 2007-10-10 Immune Targeting Systems Its L Influenza antigen delivery vectors and constructs
GB0408164D0 (en) 2004-04-13 2004-05-19 Immune Targeting Systems Ltd Antigen delivery vectors and constructs
WO2005103679A2 (en) 2004-04-21 2005-11-03 Algonomics Nv Method for affinity scoring of peptide/protein complexes
CN1954068B (en) * 2004-04-30 2011-03-02 日本电气株式会社 HLA-binding peptide, precursor thereof, DNA fragment encoding the same and recombinant vector
JP5176099B2 (en) * 2004-09-27 2013-04-03 国立大学法人 東京医科歯科大学 HLA-A11 restricted Tax anti-tumor epitope
WO2007029778A1 (en) * 2005-09-07 2007-03-15 Nec Corporation Hla-binding peptide, dna fragment encoding the peptide, and recombinant vector
JP2009536157A (en) 2006-04-13 2009-10-08 ペプチミューン，インコーポレイテッド Methods of designing and synthesizing directed sequence polymer compositions via directed extension of epitope permeability
WO2008010010A1 (en) * 2006-07-12 2008-01-24 Vaxon Biotech Identification, optimization and use of cryptic hla-b7 epitopes for immunotherapy
AP3467A (en) 2007-10-16 2015-11-30 Peptimmune Inc Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes
JP5573679B2 (en) * 2008-01-18 2014-08-20 アエラス グローバル ティービー ワクチン ファウンデーション Malaria vaccine composition and components eliciting cell-mediated immunity
EP2391635B1 (en) 2009-01-28 2017-04-26 Epimmune Inc. Pan-dr binding polypeptides and uses thereof
WO2011041490A1 (en) * 2009-09-30 2011-04-07 Saint Louis University Peptides for inducing heterosubtypic influenza t cell responses
US20130183376A1 (en) 2010-09-08 2013-07-18 Saitama Medical University Hepatitis c virus liposome vaccine
DK3138581T3 (en) 2011-03-17 2019-04-15 Univ Birmingham REDIRECTED IMMUNTERY
CN102286075A (en) * 2011-08-01 2011-12-21 中国人民解放军第三军医大学 Hepatitis B virus surface antigen immunodominance HLA-A*1101 restricted cytotoxic T lymphocyte (CTL) epitope and use thereof
US9517252B2 (en) 2011-09-09 2016-12-13 Agency For Science, Technology And Research p53 activating peptides
BR112014017819B1 (en) * 2012-01-20 2024-01-09 Fernando Thomé Kreutz METHOD OF PRODUCING ISOLATED IMMUNOGENIC CANCER CELLS
JP5999703B2 (en) * 2013-01-09 2016-09-28 国立大学法人 東京医科歯科大学 HLA-DR1-restricted Tax-specific CD4 + T cell epitope
CA2975439A1 (en) * 2015-02-18 2016-08-25 F.Hoffmann-La Roche Ag Immunoconjugates for specific induction of t cell cytotoxicity against a target cell
CN105037559B (en) * 2015-08-17 2018-09-25 北京康爱瑞浩生物科技股份有限公司 Treat or prevent the cytotoxic T lymphocyte and preparation method thereof of hepatitis B
GB201515321D0 (en) 2015-08-28 2015-10-14 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
IL309003A (en) 2015-08-28 2024-01-01 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides and scaffolds for use in immunothera-peutic treatment of various cancers
CN111148528A (en) 2016-12-28 2020-05-12 英福瓦克思公司 Influenza vaccine
CN111655280A (en) * 2017-09-01 2020-09-11 达纳-法伯癌症研究所股份有限公司 BCMA and TACI antigen specific immunogenic peptides for the treatment of cancer
EP3545967A1 (en) * 2018-03-28 2019-10-02 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Cancer immunization platform
SG11202107510SA (en) * 2019-01-11 2021-08-30 Agency Science Tech & Res Use of hla-a*11:01-restricted hepatitis b virus (hbv) peptides for identifying hbv-specific cd8+ t cells
BR112021017404A2 (en) * 2019-03-04 2022-02-01 Univ Health Network T cell receptors and methods of using them

Citations (5)

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Publication number Priority date Publication date Assignee Title
WO1994003205A1 (en) * 1992-08-07 1994-02-17 Cytel Corporation Hla binding peptides and their uses
WO1997033602A1 (en) * 1996-03-11 1997-09-18 Cytel Corporation Peptides with increased binding affinity for hla molecules
WO1997034617A1 (en) * 1996-03-21 1997-09-25 Cytel Corporation Hla binding peptides and their uses
WO1997034621A1 (en) * 1996-03-21 1997-09-25 Cytel Corporation Hla-a2.1 binding peptides and their uses
WO1998032456A1 (en) * 1997-01-23 1998-07-30 Epimmune, Inc. Identification of broadly reactive dr restricted epitopes

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
WO1994003205A1 (en) * 1992-08-07 1994-02-17 Cytel Corporation Hla binding peptides and their uses
WO1997033602A1 (en) * 1996-03-11 1997-09-18 Cytel Corporation Peptides with increased binding affinity for hla molecules
WO1997034617A1 (en) * 1996-03-21 1997-09-25 Cytel Corporation Hla binding peptides and their uses
WO1997034621A1 (en) * 1996-03-21 1997-09-25 Cytel Corporation Hla-a2.1 binding peptides and their uses
WO1998032456A1 (en) * 1997-01-23 1998-07-30 Epimmune, Inc. Identification of broadly reactive dr restricted epitopes

Non-Patent Citations (4)

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Title
ALTUVIA YAEL ET AL: "A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets", HUMAN IMMUNOLOGY, vol. 58, no. 1, November 1997 (1997-11-01), pages 1 - 11, XP002279422, ISSN: 0198-8859 *
GREY H M ET AL: "CLASS I MHC-PEPTIDE INTERACTIONS: STRUCTURAL REQUIREMENTS AND FUNCTIONAL IMPLICATIONS", CANCER SURVEYS, OXFORD, GB, vol. 22, 1995, pages 37 - 49, XP008024840 *
PARTIDOS C D ET AL: "Induction of measles virus-specific cytotoxic T-cell responses after intranasal immunization with synthetic peptides", IMMUNOLOGY, vol. 87, no. 2, 1996, pages 179 - 185, XP002279421, ISSN: 0019-2805 *
See also references of WO9945954A1 *

Also Published As

Publication number Publication date
JP2002507397A (en) 2002-03-12
CA2323632A1 (en) 1999-09-16
EP1064022A1 (en) 2001-01-03
WO1999045954A1 (en) 1999-09-16
AU6465598A (en) 1999-09-27

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Owner name: EPIMMUNE INC.

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Ipc: 7C 07K 14/82 B

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