EP1064022A4 - Hla-bindeproteine und deren verwendung - Google Patents
Hla-bindeproteine und deren verwendungInfo
- Publication number
- EP1064022A4 EP1064022A4 EP98910404A EP98910404A EP1064022A4 EP 1064022 A4 EP1064022 A4 EP 1064022A4 EP 98910404 A EP98910404 A EP 98910404A EP 98910404 A EP98910404 A EP 98910404A EP 1064022 A4 EP1064022 A4 EP 1064022A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hla
- binding peptides
- peptides
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/005039 WO1999045954A1 (en) | 1998-03-13 | 1998-03-13 | Hla-binding peptides and their uses |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1064022A1 EP1064022A1 (de) | 2001-01-03 |
EP1064022A4 true EP1064022A4 (de) | 2004-09-29 |
Family
ID=22266589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98910404A Withdrawn EP1064022A4 (de) | 1998-03-13 | 1998-03-13 | Hla-bindeproteine und deren verwendung |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1064022A4 (de) |
JP (1) | JP2002507397A (de) |
AU (1) | AU6465598A (de) |
CA (1) | CA2323632A1 (de) |
WO (1) | WO1999045954A1 (de) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7611713B2 (en) | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
US9340577B2 (en) | 1992-08-07 | 2016-05-17 | Epimmune Inc. | HLA binding motifs and peptides and their uses |
US6716809B1 (en) | 1997-09-12 | 2004-04-06 | Ludwig Institute For Cancer Research | Mage-A3 peptides presented by HLA class molecules |
US6291430B1 (en) | 1997-09-12 | 2001-09-18 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
US6183746B1 (en) | 1997-10-09 | 2001-02-06 | Zycos Inc. | Immunogenic peptides from the HPV E7 protein |
US6407063B1 (en) * | 1998-10-02 | 2002-06-18 | Ludwig Institute For Cancer Research | Tumor antigens and CTL clones isolated by a novel procedure |
EP1117679B9 (de) | 1998-10-02 | 2010-07-07 | Ludwig Institute For Cancer Research | Tumorantigene und ctl-klone, die durch ein neues verfahren isoliert wurden |
US6541214B1 (en) * | 1998-11-13 | 2003-04-01 | Oregon Heath Science University | N-terminally truncated HER-2/neu protein as a cancer prognostic indicator |
GB9826143D0 (en) * | 1998-11-27 | 1999-01-20 | Ludwig Inst Cancer Res | Tumour rejection antigens |
NZ512052A (en) * | 1998-12-01 | 2003-10-31 | Sumitomo Pharma | Novel tumor antigen protein art-1 and tumor antigen peptide thereof |
IT1309584B1 (it) * | 1999-02-26 | 2002-01-24 | San Raffaele Centro Fond | Peptidi immunogenici derivati da mage-3 presentati da mhc di classeii e loro uso. |
AU1440601A (en) * | 1999-10-29 | 2001-05-14 | Argonex Pharmaceuticals, Inc. | Cytotoxic t lymphocyte-stimulating peptides for prevention, treatment, and diagnosis of melanoma |
ATE445643T1 (de) * | 1999-11-18 | 2009-10-15 | Pharmexa Inc | Heteroklitische analoga von klasse-i epitopen |
WO2001041787A1 (en) * | 1999-12-10 | 2001-06-14 | Epimmune Inc. | INDUCING CELLULAR IMMUNE RESPONSES TO HER2/neu USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS |
US7026443B1 (en) * | 1999-12-10 | 2006-04-11 | Epimmune Inc. | Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions |
EP1237564A4 (de) * | 1999-12-10 | 2005-05-04 | Epimmune Inc | Induktion zellulärer immunantworten gegen p53 mittels peptid und nukleinsäure-verbindungen |
EP1235841A4 (de) * | 1999-12-10 | 2006-04-12 | Epimmune Inc | Induzierung von zellulärer immunantwort auf mage2/3 mit hilfe von peptid- und nukleinsäurezubereitungen |
JP2003521245A (ja) * | 1999-12-21 | 2003-07-15 | エピミューン, インコーポレイテッド | ペプチドおよび核酸組成物を使用する、前立腺癌抗原に対する細胞性免疫応答の誘導 |
US7462354B2 (en) | 1999-12-28 | 2008-12-09 | Pharmexa Inc. | Method and system for optimizing minigenes and peptides encoded thereby |
FR2806727A1 (fr) * | 2000-03-23 | 2001-09-28 | Pf Medicament | Molecule d'interet pharmaceutique comprotant en son extremite n-terminale un acide glutamique ou une glutamine sous forme de sel d'addition d'acide fort physiologiquement acceptable |
WO2001074847A2 (en) * | 2000-03-30 | 2001-10-11 | The Government Of The United States Of America Represented By The Secretary, Department Of Health And Human Services | T-cell epitope of mage-12 and related nucleic acids, vectors, cells, compositions and methods of inducing an immune response to cancer |
CN1107681C (zh) * | 2000-08-11 | 2003-05-07 | 中国科学院微生物研究所 | 乙肝病毒抗原多肽与热休克蛋白的复合物及其应用 |
AU2001295008A1 (en) * | 2000-08-14 | 2002-02-25 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of Her-2/neu-associated malignancies |
WO2002020053A1 (en) * | 2000-09-01 | 2002-03-14 | Epimmune Inc. | Hla binding peptides and their uses |
EP1195381A1 (de) * | 2000-09-28 | 2002-04-10 | Immusystems GmbH | CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope |
AU2002239410B2 (en) | 2000-10-31 | 2008-05-01 | Eisai Inc. | CYP1B1 nucleic acids and methods of use |
EP1490396A4 (de) * | 2001-03-01 | 2006-04-19 | Us Gov Health & Human Serv | Immunogene hiv-peptide zur verwendung als reagentien und impfstoffe |
CN100589845C (zh) * | 2001-03-07 | 2010-02-17 | 麦康公司 | 用于治疗癌症的抗新血管系统制剂 |
EP1752160A3 (de) * | 2001-04-06 | 2007-05-30 | Mannkind Corporation | Epitop-Sequenzen |
WO2003008537A2 (en) * | 2001-04-06 | 2003-01-30 | Mannkind Corporation | Epitope sequences |
WO2002080848A2 (en) | 2001-04-09 | 2002-10-17 | Mayo Foundation For Medical Education And Research | Methods and materials for cancer treatment |
WO2002094994A2 (en) | 2001-05-18 | 2002-11-28 | Mayo Foundation For Medical Education And Research | Chimeric antigen-specific t cell-activating polypeptides |
US7049413B2 (en) | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
US20060222656A1 (en) | 2005-04-01 | 2006-10-05 | University Of Maryland, Baltimore | MAGE-A3/HPV 16 peptide vaccines for head and neck cancer |
CA2449715A1 (en) * | 2001-06-05 | 2002-12-12 | The Government Of The United States Of America As Represented By The Sec Retary Of The Department Of Health And Human Services, Centers For Disea | Peptides for chlamydophila pneumoniae vaccine and diagnosis |
US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
CA2357906A1 (en) | 2001-09-28 | 2003-03-28 | Institut Pasteur | Identification of new cd8 epitopes from hiv-1 proteins with therapeutical and vaccinal properties against hiv infections |
WO2003063770A2 (en) | 2001-11-07 | 2003-08-07 | Mannkind Corporation | Expression vectors encoding epitopes of target-associated antigens and methods for their design |
AU2002349543A1 (en) * | 2001-12-10 | 2003-06-23 | Kyogo Itoh | Tumor antigens |
US20060018915A1 (en) * | 2002-04-05 | 2006-01-26 | Glenn Ishioka | Heteroclitic analogs and related methods |
DK1587837T3 (da) | 2003-01-28 | 2012-09-24 | Proscan Rx Pharma Inc | Epitopsekvenser til diagnose og behandling af prostatacancer |
JPWO2005007694A1 (ja) * | 2003-07-16 | 2007-09-20 | 株式会社グリーンペプタイド | HER2/neuペプチドおよびその治療上の用途 |
EP2481422A3 (de) * | 2003-09-03 | 2013-04-03 | Dendritherapeutics, Inc. | Multiplex-Impfstoffe |
US7488793B2 (en) * | 2003-09-22 | 2009-02-10 | Ludwig Institute For Cancer Research | Isolated peptide which binds to HLA-Cw*07 and uses thereof |
CA2539789A1 (en) * | 2003-09-22 | 2005-03-31 | Green Peptide Co., Ltd. | Peptide originating in hepatitis c virus |
US9090673B2 (en) | 2003-12-12 | 2015-07-28 | City Of Hope | Synthetic conjugate of CpG DNA and T-help/CTL peptide |
GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
GB0716992D0 (en) | 2007-08-31 | 2007-10-10 | Immune Targeting Systems Its L | Influenza antigen delivery vectors and constructs |
WO2005103679A2 (en) | 2004-04-21 | 2005-11-03 | Algonomics Nv | Method for affinity scoring of peptide/protein complexes |
US20080249283A1 (en) * | 2004-04-30 | 2008-10-09 | Tomoya Miyakawa | Hla-Binding Peptides, Precursors Thereof, Dna Fragments and Recombinant Vectors that Code for Those Peptide Sequences |
WO2006035681A1 (ja) * | 2004-09-27 | 2006-04-06 | National University Corporation Tokyo Medical And Dental University | HLA-A11拘束性Tax抗腫瘍エピトープ |
US20080306243A1 (en) * | 2005-09-07 | 2008-12-11 | Nec Corporation | Hla-Binding Peptide, and Dna Fragment and Recombinant Vector Coding for Said Hla-Binding Peptide |
EP2016095A2 (de) | 2006-04-13 | 2009-01-21 | Peptimmune, Inc. | Verfahren zur entwicklung und synthese von zusammensetzungen mit einem polymer mit gerichteter sequenz über die gerichtete expansion der epitoppermeabilität |
WO2008010010A1 (en) * | 2006-07-12 | 2008-01-24 | Vaxon Biotech | Identification, optimization and use of cryptic hla-b7 epitopes for immunotherapy |
AP3467A (en) | 2007-10-16 | 2015-11-30 | Peptimmune Inc | Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes |
JP5573679B2 (ja) | 2008-01-18 | 2014-08-20 | アエラス グローバル ティービー ワクチン ファウンデーション | マラリアワクチン組成物および細胞媒介免疫性を惹起する成分 |
EP2391635B1 (de) | 2009-01-28 | 2017-04-26 | Epimmune Inc. | Pan-dr-bindende polypeptide und verwendungen davon |
CA2775720A1 (en) * | 2009-09-30 | 2011-04-07 | Saint Louis University | Peptides for inducing heterosubtypic influenza t cell responses |
US20130183376A1 (en) * | 2010-09-08 | 2013-07-18 | Saitama Medical University | Hepatitis c virus liposome vaccine |
WO2012123755A1 (en) | 2011-03-17 | 2012-09-20 | The University Of Birmingham | Re-directed immunotherapy |
CN102286075A (zh) * | 2011-08-01 | 2011-12-21 | 中国人民解放军第三军医大学 | 乙肝病毒表面抗原的免疫显性hla-a*1101限制性ctl表位及其应用 |
WO2013036208A1 (en) * | 2011-09-09 | 2013-03-14 | Agency For Science, Technology And Research | P53 activating peptides |
KR102047323B1 (ko) * | 2012-01-20 | 2019-11-21 | 페르난도 토메 크뤠츠 | 자가 암 세포 백신 |
JP5999703B2 (ja) * | 2013-01-09 | 2016-09-28 | 国立大学法人 東京医科歯科大学 | HLA−DR1拘束性Tax特異的CD4+T細胞エピトープ |
AU2016221777A1 (en) * | 2015-02-18 | 2017-08-31 | F. Hoffmann-La Roche Ag | Immunoconjugates for specific induction of T cell cytotoxicity against a target cell |
CN105037559B (zh) * | 2015-08-17 | 2018-09-25 | 北京康爱瑞浩生物科技股份有限公司 | 治疗或预防乙肝的细胞毒性t淋巴细胞及其制备方法 |
IL309003A (en) | 2015-08-28 | 2024-01-01 | Immatics Biotechnologies Gmbh | New peptides and a combination of peptides and supports for use in immunotherapy in different types of cancer |
GB201515321D0 (en) | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
MX2019007924A (es) | 2016-12-28 | 2020-01-27 | Invvax Inc | Vacunas contra la influenza. |
KR20200047660A (ko) * | 2017-09-01 | 2020-05-07 | 다나-파버 캔서 인스티튜트 인크. | 암의 치료를 위한 bcma 및 taci 항원에 특이적인 면역원성 펩타이드 |
EP3545967A1 (de) * | 2018-03-28 | 2019-10-02 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Krebsimmunisierungsplattform |
CN113939527A (zh) * | 2019-01-11 | 2022-01-14 | 新加坡科技研究局 | Hla-a*11:01限制性乙型肝炎病毒(hbv)肽用于鉴别hbv特异性cd8+ t细胞的用途 |
AU2020231928A1 (en) * | 2019-03-04 | 2021-10-07 | University Health Network | T cell receptors and methods of use thereof |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003205A1 (en) * | 1992-08-07 | 1994-02-17 | Cytel Corporation | Hla binding peptides and their uses |
WO1997033602A1 (en) * | 1996-03-11 | 1997-09-18 | Cytel Corporation | Peptides with increased binding affinity for hla molecules |
WO1997034621A1 (en) * | 1996-03-21 | 1997-09-25 | Cytel Corporation | Hla-a2.1 binding peptides and their uses |
WO1997034617A1 (en) * | 1996-03-21 | 1997-09-25 | Cytel Corporation | Hla binding peptides and their uses |
WO1998032456A1 (en) * | 1997-01-23 | 1998-07-30 | Epimmune, Inc. | Identification of broadly reactive dr restricted epitopes |
-
1998
- 1998-03-13 AU AU64655/98A patent/AU6465598A/en not_active Abandoned
- 1998-03-13 CA CA002323632A patent/CA2323632A1/en not_active Abandoned
- 1998-03-13 JP JP2000535367A patent/JP2002507397A/ja active Pending
- 1998-03-13 EP EP98910404A patent/EP1064022A4/de not_active Withdrawn
- 1998-03-13 WO PCT/US1998/005039 patent/WO1999045954A1/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994003205A1 (en) * | 1992-08-07 | 1994-02-17 | Cytel Corporation | Hla binding peptides and their uses |
WO1997033602A1 (en) * | 1996-03-11 | 1997-09-18 | Cytel Corporation | Peptides with increased binding affinity for hla molecules |
WO1997034621A1 (en) * | 1996-03-21 | 1997-09-25 | Cytel Corporation | Hla-a2.1 binding peptides and their uses |
WO1997034617A1 (en) * | 1996-03-21 | 1997-09-25 | Cytel Corporation | Hla binding peptides and their uses |
WO1998032456A1 (en) * | 1997-01-23 | 1998-07-30 | Epimmune, Inc. | Identification of broadly reactive dr restricted epitopes |
Non-Patent Citations (4)
Title |
---|
ALTUVIA YAEL ET AL: "A structure-based algorithm to predict potential binding peptides to MHC molecules with hydrophobic binding pockets", HUMAN IMMUNOLOGY, vol. 58, no. 1, November 1997 (1997-11-01), pages 1 - 11, XP002279422, ISSN: 0198-8859 * |
GREY H M ET AL: "CLASS I MHC-PEPTIDE INTERACTIONS: STRUCTURAL REQUIREMENTS AND FUNCTIONAL IMPLICATIONS", CANCER SURVEYS, OXFORD, GB, vol. 22, 1995, pages 37 - 49, XP008024840 * |
PARTIDOS C D ET AL: "Induction of measles virus-specific cytotoxic T-cell responses after intranasal immunization with synthetic peptides", IMMUNOLOGY, vol. 87, no. 2, 1996, pages 179 - 185, XP002279421, ISSN: 0019-2805 * |
See also references of WO9945954A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999045954A1 (en) | 1999-09-16 |
CA2323632A1 (en) | 1999-09-16 |
AU6465598A (en) | 1999-09-27 |
EP1064022A1 (de) | 2001-01-03 |
JP2002507397A (ja) | 2002-03-12 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20000929 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: EPIMMUNE INC. |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 07K 14/82 B Ipc: 7C 07K 14/02 B Ipc: 7C 07K 7/00 B Ipc: 7A 61K 39/00 B Ipc: 7A 61K 39/29 A |
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A4 | Supplementary search report drawn up and despatched |
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Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20080401 |