MXPA03000199A - Xantones policiclicos nuevos y su uso. - Google Patents

Xantones policiclicos nuevos y su uso.

Info

Publication number
MXPA03000199A
MXPA03000199A MXPA03000199A MXPA03000199A MXPA03000199A MX PA03000199 A MXPA03000199 A MX PA03000199A MX PA03000199 A MXPA03000199 A MX PA03000199A MX PA03000199 A MXPA03000199 A MX PA03000199A MX PA03000199 A MXPA03000199 A MX PA03000199A
Authority
MX
Mexico
Prior art keywords
alkyl
hydrogen
class
compounds
new polycyclic
Prior art date
Application number
MXPA03000199A
Other languages
English (en)
Inventor
Francisco Romero
Original Assignee
Canedo Librada Maria
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canedo Librada Maria filed Critical Canedo Librada Maria
Publication of MXPA03000199A publication Critical patent/MXPA03000199A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/03—Actinomadura

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Mold Materials And Core Materials (AREA)

Abstract

Ha sido reconocida una clase novedosa de compuestos antitumorales basados en el aislamiento de un nuevo microbio marino, cepa PO13-046, que pertenece al (genus Actinomadura sp.), de un compuesto designado IB-00208. La clase de las formulas (I) o (II) en donde R1 puede ser hidrogeno, acilo, alquilo, alquenilo, arilo, bencilo, metal alcalino y/o azucar, y R2 y R3 pueden ser hidrogeno, alquilo o juntos R2 y R3 forman un enlace insaturado. Dichos compuestos demuestran varias lineas celulares cancerosas de actividad interesante y contra la bacteria Gram-positiva.
MXPA03000199A 2000-06-29 2001-06-29 Xantones policiclicos nuevos y su uso. MXPA03000199A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0016020.0A GB0016020D0 (en) 2000-06-29 2000-06-29 New polyciclic xanthones and their use
PCT/GB2001/002898 WO2002000663A2 (en) 2000-06-29 2001-06-29 Polycyclic xanthones as antibiotics

Publications (1)

Publication Number Publication Date
MXPA03000199A true MXPA03000199A (es) 2004-02-26

Family

ID=9894705

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03000199A MXPA03000199A (es) 2000-06-29 2001-06-29 Xantones policiclicos nuevos y su uso.

Country Status (21)

Country Link
US (1) US6812245B2 (es)
EP (1) EP1296989B1 (es)
JP (1) JP2004501924A (es)
KR (1) KR100801068B1 (es)
CN (1) CN1273470C (es)
AT (1) ATE362935T1 (es)
AU (2) AU6620601A (es)
BR (1) BR0112090A (es)
CA (1) CA2412559A1 (es)
CY (1) CY1106805T1 (es)
DE (1) DE60128565T2 (es)
DK (1) DK1296989T3 (es)
ES (1) ES2287135T3 (es)
GB (1) GB0016020D0 (es)
HK (1) HK1052707B (es)
IL (2) IL153679A0 (es)
MX (1) MXPA03000199A (es)
NZ (1) NZ523338A (es)
PT (1) PT1296989E (es)
RU (1) RU2285008C2 (es)
WO (1) WO2002000663A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101372538B (zh) 2007-08-21 2012-08-29 北京万和芯源生物技术有限公司 紫外光辅助的表面改性方法及具有由此方法形成的表面的制品
WO2009085360A2 (en) * 2007-10-04 2009-07-09 Novobiotic Pharmaceuticals Llc Citreamicin antibiotic with a sugar residue
WO2009085359A2 (en) * 2007-10-04 2009-07-09 Novobiotic Pharmaceuticals Llc Citreamicin antibiotic isolated from nocardia
CN101889998B (zh) * 2010-05-28 2012-10-03 暨南大学 一种组合物及其在制备tr3受体诱导剂中的应用
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام
CN110627640B (zh) * 2017-09-19 2020-10-30 浙江大学 一种暗黄链霉酸和暗黄链霉酮的制备及其医药用途
CN109320527B (zh) * 2018-11-12 2020-08-28 中国医学科学院医药生物技术研究所 鹿色霉素(cervinomycin)B1、B2、B3、B4及其生产方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57102897A (en) 1980-12-17 1982-06-26 Kitasato Inst:The Antibiotic am-5344-a2 and its preparation
JPH0755951B2 (ja) 1986-02-17 1995-06-14 北里研究所（社団法人） セルビノマイシン系抗生物質誘導体およびその製造法
JPS62270527A (ja) 1986-05-16 1987-11-24 Taiho Yakuhin Kogyo Kk ４１８１−２物質及びその誘導体を有効成分とする抗腫瘍剤
JPS62270587A (ja) 1986-05-16 1987-11-24 Taiho Yakuhin Kogyo Kk ４１８１−２物質及びそのアシル誘導体
AU599650B2 (en) 1986-05-16 1990-07-26 Taiho Pharmaceutical Co., Ltd. Substance 4181-2 and its derivatives
EP0353381A3 (en) 1988-08-04 1991-01-02 American Cyanamid Company Antibiotic ll-e19085 alpha
US5223430A (en) 1988-08-04 1993-06-29 American Cyanamid Company Subspecies of micromonospora citrea which produces antibiotic ll-e19085 alpha
US5096907A (en) 1989-06-29 1992-03-17 American Cyanamid Company Antibiotic LL-E19085
EP0405151A1 (en) 1989-06-29 1991-01-02 American Cyanamid Company Antibiotic LL-E19085
EP0442003A1 (en) 1990-02-13 1991-08-21 American Cyanamid Company Antibiotic LL-E 19085 alpha
GB0011927D0 (en) 2000-05-17 2000-07-05 Inst Biomar Sa New use of citreamicins

Also Published As

Publication number Publication date
HK1052707A1 (en) 2003-09-26
EP1296989B1 (en) 2007-05-23
JP2004501924A (ja) 2004-01-22
DK1296989T3 (da) 2007-09-24
WO2002000663A2 (en) 2002-01-03
GB0016020D0 (en) 2000-08-23
ATE362935T1 (de) 2007-06-15
CN1449399A (zh) 2003-10-15
HK1052707B (zh) 2007-09-21
WO2002000663A3 (en) 2002-05-30
ES2287135T3 (es) 2007-12-16
AU2001266206B2 (en) 2006-08-10
AU6620601A (en) 2002-01-08
CN1273470C (zh) 2006-09-06
KR100801068B1 (ko) 2008-02-04
IL153679A (en) 2008-06-05
CY1106805T1 (el) 2012-05-23
US20040009928A1 (en) 2004-01-15
PT1296989E (pt) 2007-08-29
RU2285008C2 (ru) 2006-10-10
BR0112090A (pt) 2003-05-06
KR20030034117A (ko) 2003-05-01
CA2412559A1 (en) 2002-01-03
DE60128565T2 (de) 2008-01-17
US6812245B2 (en) 2004-11-02
NZ523338A (en) 2005-07-29
DE60128565D1 (en) 2007-07-05
EP1296989A2 (en) 2003-04-02
IL153679A0 (en) 2003-07-06

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