MXPA02012163A - Composiciones farmaceuticas que comprenden derivados de acriloil-distamicina e inhibidores de topoisomerasa 1 y 11. - Google Patents
Composiciones farmaceuticas que comprenden derivados de acriloil-distamicina e inhibidores de topoisomerasa 1 y 11.Info
- Publication number
- MXPA02012163A MXPA02012163A MXPA02012163A MXPA02012163A MXPA02012163A MX PA02012163 A MXPA02012163 A MX PA02012163A MX PA02012163 A MXPA02012163 A MX PA02012163A MX PA02012163 A MXPA02012163 A MX PA02012163A MX PA02012163 A MXPA02012163 A MX PA02012163A
- Authority
- MX
- Mexico
- Prior art keywords
- topoisomerase
- inhibitors
- distamycin derivatives
- acryloyl distamycin
- combined therapy
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 108090000323 DNA Topoisomerases Chemical class 0.000 title abstract 2
- 102000003915 DNA Topoisomerases Human genes 0.000 title abstract 2
- 108010046308 Type II DNA Topoisomerases Chemical class 0.000 title abstract 2
- 102000007537 Type II DNA Topoisomerases Human genes 0.000 title abstract 2
- -1 acryloyl distamycin derivatives Chemical class 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 238000002648 combination therapy Methods 0.000 title 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 230000014399 negative regulation of angiogenesis Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0015444.3A GB0015444D0 (en) | 2000-06-23 | 2000-06-23 | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| PCT/EP2001/007059 WO2001097789A2 (en) | 2000-06-23 | 2001-06-20 | Pharmaceutical compositions comprising acryloyl distamycin derivatives and topoisomerase i and ii inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02012163A true MXPA02012163A (es) | 2003-04-25 |
Family
ID=9894285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02012163A MXPA02012163A (es) | 2000-06-23 | 2001-06-20 | Composiciones farmaceuticas que comprenden derivados de acriloil-distamicina e inhibidores de topoisomerasa 1 y 11. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20030162722A1 (enExample) |
| EP (1) | EP1292290B1 (enExample) |
| JP (1) | JP2003535890A (enExample) |
| KR (1) | KR100853955B1 (enExample) |
| CN (1) | CN1241573C (enExample) |
| AT (1) | ATE323483T1 (enExample) |
| AU (2) | AU7846301A (enExample) |
| BR (1) | BR0111813A (enExample) |
| CA (1) | CA2411172C (enExample) |
| CZ (1) | CZ20024155A3 (enExample) |
| DE (1) | DE60118914T2 (enExample) |
| DK (1) | DK1292290T3 (enExample) |
| EA (1) | EA006684B1 (enExample) |
| EE (1) | EE05319B1 (enExample) |
| ES (1) | ES2261448T3 (enExample) |
| GB (1) | GB0015444D0 (enExample) |
| HK (1) | HK1054334B (enExample) |
| HU (1) | HUP0301257A2 (enExample) |
| IL (1) | IL153177A0 (enExample) |
| MX (1) | MXPA02012163A (enExample) |
| NO (1) | NO329783B1 (enExample) |
| NZ (1) | NZ523000A (enExample) |
| PL (1) | PL200503B1 (enExample) |
| PT (1) | PT1292290E (enExample) |
| SK (1) | SK287549B6 (enExample) |
| WO (1) | WO2001097789A2 (enExample) |
| ZA (1) | ZA200209834B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0015447D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| GB0015444D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
| DE60210329T2 (de) * | 2002-01-02 | 2006-11-30 | Nerviano Medical Sciences S.R.L., Nerviano | Kombinierte tumortherapie auf der basis von substituierten acryloyl-distamycin-derivaten und protein-kinase (serin/threonin-kinase) inhibitoren |
| CN100438913C (zh) * | 2004-11-22 | 2008-12-03 | 山东蓝金生物工程有限公司 | 一种抗癌药物组合物 |
| MD36Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului ductal in situ neinvaziv al glandei mamare |
| MD23Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului lobular in situ neinvaziv al glandei mamare |
| MD35Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de apreciere a riscului dezvoltării carcinomului neinvaziv in situ al glandei mamare |
| MD24Z (ro) * | 2008-12-02 | 2010-01-31 | Василе ЖОВМИР | Metodă de tratament diferenţiat al carcinomului neinvaziv al glandei mamare |
| EP2588490B1 (en) | 2010-07-02 | 2017-02-22 | Angiochem Inc. | Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
| CN109718228A (zh) * | 2017-10-30 | 2019-05-07 | 沈阳药科大学 | 米托蒽醌的抗肿瘤淋巴转移作用及其药物制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9615692D0 (en) * | 1996-07-25 | 1996-09-04 | Pharmacia Spa | Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents |
| GB9623522D0 (en) * | 1996-11-11 | 1997-01-08 | Pharmacia & Upjohn Spa | Benzoheterocycle distamycin derivatives process for preparing them and their use as antitumour and antiviral agents |
| GB9727524D0 (en) * | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Synergistic antitumor composition containing a biologically active ureido compound |
| GB9806692D0 (en) * | 1998-03-27 | 1998-05-27 | Pharmacia & Upjohn Spa | Benzoheterocyclic distamycin derivatives, process for preparing them and their use as antitumour agents |
| GB0015444D0 (en) * | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors |
-
2000
- 2000-06-23 GB GBGB0015444.3A patent/GB0015444D0/en not_active Ceased
-
2001
- 2001-06-20 HU HU0301257A patent/HUP0301257A2/hu unknown
- 2001-06-20 MX MXPA02012163A patent/MXPA02012163A/es active IP Right Grant
- 2001-06-20 PL PL360297A patent/PL200503B1/pl not_active IP Right Cessation
- 2001-06-20 ES ES01956495T patent/ES2261448T3/es not_active Expired - Lifetime
- 2001-06-20 KR KR1020027017440A patent/KR100853955B1/ko not_active Expired - Fee Related
- 2001-06-20 DE DE60118914T patent/DE60118914T2/de not_active Expired - Lifetime
- 2001-06-20 EE EEP200200681A patent/EE05319B1/xx not_active IP Right Cessation
- 2001-06-20 BR BR0111813-7A patent/BR0111813A/pt not_active Application Discontinuation
- 2001-06-20 EA EA200300060A patent/EA006684B1/ru not_active IP Right Cessation
- 2001-06-20 DK DK01956495T patent/DK1292290T3/da active
- 2001-06-20 IL IL15317701A patent/IL153177A0/xx not_active IP Right Cessation
- 2001-06-20 US US10/297,915 patent/US20030162722A1/en not_active Abandoned
- 2001-06-20 CN CNB018116396A patent/CN1241573C/zh not_active Expired - Fee Related
- 2001-06-20 NZ NZ523000A patent/NZ523000A/en unknown
- 2001-06-20 AU AU7846301A patent/AU7846301A/xx active Pending
- 2001-06-20 EP EP01956495A patent/EP1292290B1/en not_active Expired - Lifetime
- 2001-06-20 WO PCT/EP2001/007059 patent/WO2001097789A2/en not_active Ceased
- 2001-06-20 CZ CZ20024155A patent/CZ20024155A3/cs unknown
- 2001-06-20 CA CA002411172A patent/CA2411172C/en not_active Expired - Fee Related
- 2001-06-20 AU AU2001278463A patent/AU2001278463B2/en not_active Ceased
- 2001-06-20 SK SK1833-2002A patent/SK287549B6/sk not_active IP Right Cessation
- 2001-06-20 PT PT01956495T patent/PT1292290E/pt unknown
- 2001-06-20 JP JP2002503266A patent/JP2003535890A/ja not_active Abandoned
- 2001-06-20 HK HK03106770.0A patent/HK1054334B/zh not_active IP Right Cessation
- 2001-06-20 AT AT01956495T patent/ATE323483T1/de not_active IP Right Cessation
-
2002
- 2002-12-04 ZA ZA200209834A patent/ZA200209834B/en unknown
- 2002-12-18 NO NO20026078A patent/NO329783B1/no not_active IP Right Cessation
Also Published As
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|---|---|---|
| AU2002213421A1 (en) | Condensed pyridoindole derivatives | |
| GB0015444D0 (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and topoisomerase I and II inhibitors | |
| AU2002213419A1 (en) | Condensed pyridoindole derivatives | |
| MXPA03004023A (es) | Compuestos quimicos. | |
| MXPA02012209A (es) | Terapia combinada contra tumores que comprende derivados de bistamicina acriloilo substituida y agentes de alquilacion. | |
| MXPA02012165A (es) | Terapia combinada contra tumores que comprende derivados de acriloil-distamicina sustituida, taxanos y/o antimetabolitos. | |
| IL162820A0 (en) | Combined therapy against tumors comprising substituted acryloyl distamycin derivatives and protein kinase (serine/threonine kinase) inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| GB | Transfer or rights |