MXPA02005870A - Inhibidores de n-[5-[[[5-alquil-2-oxazolil)metil)tio)-2-tiazolil)carboxamida de cinasas dependientes de ciclina. - Google Patents
Inhibidores de n-[5-[[[5-alquil-2-oxazolil)metil)tio)-2-tiazolil)carboxamida de cinasas dependientes de ciclina.Info
- Publication number
- MXPA02005870A MXPA02005870A MXPA02005870A MXPA02005870A MXPA02005870A MX PA02005870 A MXPA02005870 A MX PA02005870A MX PA02005870 A MXPA02005870 A MX PA02005870A MX PA02005870 A MXPA02005870 A MX PA02005870A MX PA02005870 A MXPA02005870 A MX PA02005870A
- Authority
- MX
- Mexico
- Prior art keywords
- hydrochloride
- pharmaceutically acceptable
- compound according
- thio
- mixture
- Prior art date
Links
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Classifications
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- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/464,511 US6262096B1 (en) | 1997-11-12 | 1999-12-15 | Aminothiazole inhibitors of cyclin dependent kinases |
| US61662700A | 2000-07-26 | 2000-07-26 | |
| PCT/US2000/033501 WO2001044242A1 (en) | 1999-12-15 | 2000-12-07 | N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]carboxamide inhibitors of cyclin dependent kinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02005870A true MXPA02005870A (es) | 2003-01-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02005870A MXPA02005870A (es) | 1999-12-15 | 2000-12-07 | Inhibidores de n-[5-[[[5-alquil-2-oxazolil)metil)tio)-2-tiazolil)carboxamida de cinasas dependientes de ciclina. |
Country Status (29)
| Country | Link |
|---|---|
| EP (1) | EP1240166B1 (enExample) |
| JP (1) | JP2003516987A (enExample) |
| KR (1) | KR100738132B1 (enExample) |
| CN (1) | CN1433416A (enExample) |
| AR (1) | AR026974A1 (enExample) |
| AT (1) | ATE289306T1 (enExample) |
| AU (1) | AU783719B2 (enExample) |
| BR (1) | BR0016424A (enExample) |
| CA (1) | CA2394552A1 (enExample) |
| CO (1) | CO5261565A1 (enExample) |
| CZ (1) | CZ20022015A3 (enExample) |
| DE (1) | DE60018205T2 (enExample) |
| DK (1) | DK1240166T3 (enExample) |
| EG (1) | EG24168A (enExample) |
| ES (1) | ES2236034T3 (enExample) |
| HK (1) | HK1049661B (enExample) |
| HU (1) | HUP0301032A3 (enExample) |
| IL (2) | IL149755A0 (enExample) |
| MX (1) | MXPA02005870A (enExample) |
| MY (1) | MY125768A (enExample) |
| NO (1) | NO323726B1 (enExample) |
| NZ (1) | NZ519120A (enExample) |
| PE (1) | PE20011026A1 (enExample) |
| PL (1) | PL364921A1 (enExample) |
| PT (1) | PT1240166E (enExample) |
| RU (1) | RU2002119016A (enExample) |
| TW (1) | TWI273103B (enExample) |
| UY (1) | UY26481A1 (enExample) |
| WO (1) | WO2001044242A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262096B1 (en) | 1997-11-12 | 2001-07-17 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
| US6414156B2 (en) * | 1998-10-21 | 2002-07-02 | Bristol-Myers Squibb Company | Process for preparing azacycloalkanoylaminothiazoles |
| US6392053B2 (en) | 1999-12-15 | 2002-05-21 | Bristol-Myers Squibb Company | Process for preparing arylacetylaminothiazoles |
| US6515004B1 (en) | 1999-12-15 | 2003-02-04 | Bristol-Myers Squibb Company | N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases |
| IL153591A0 (en) * | 2000-07-26 | 2003-07-06 | Bristol Myers Squibb Co | N-[5-(((5-alkyl-2-oxazolyl) methyl) thio)-2-thiazolyl] carboxamide and pharmaceutical compositions containing the same |
| US7473691B2 (en) | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| EP1318814B1 (en) | 2000-09-15 | 2007-05-30 | Vertex Pharmaceuticals Incorporated | Triazole compounds useful as protein kinase inhibitors |
| US7625913B2 (en) | 2000-12-21 | 2009-12-01 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
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| AU2015371251B2 (en) | 2014-12-23 | 2020-06-11 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 (CDK7) |
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| US6040321A (en) * | 1997-11-12 | 2000-03-21 | Bristol-Myers Squibb Company | Aminothiazole inhibitors of cyclin dependent kinases |
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