MXPA02001308A - Derivados de pirido (1, 2-a)bencimidazol sustituidos en el anillo c-6 utiles en el tratamiento de trastornos del sistema nervioso central. - Google Patents

Derivados de pirido (1, 2-a)bencimidazol sustituidos en el anillo c-6 utiles en el tratamiento de trastornos del sistema nervioso central.

Info

Publication number
MXPA02001308A
MXPA02001308A MXPA02001308A MXPA02001308A MXPA02001308A MX PA02001308 A MXPA02001308 A MX PA02001308A MX PA02001308 A MXPA02001308 A MX PA02001308A MX PA02001308 A MXPA02001308 A MX PA02001308A MX PA02001308 A MXPA02001308 A MX PA02001308A
Authority
MX
Mexico
Prior art keywords
pyrido
ringsubstituted
benzimidazole
benzimidazole derivative
substituted pyrido
Prior art date
Application number
MXPA02001308A
Other languages
English (en)
Inventor
K Scott Malcolm
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA02001308A publication Critical patent/MXPA02001308A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Un derivado de pirido (1 2-a)benzimidazol sustituido en el anillo C-6 de formula (1): se describen metodos de preparacion y composiciones farmaceuticas que contienen un derivado de pirido [1, 2-a]benzimidazol sustituido como el ingrediente activo; los derivados de pirido [1, 2- a]benzimidazol sustituidos son utiles en el tratamiento de transtornos del sistema nervioso central.
MXPA02001308A 1999-08-02 2000-07-20 Derivados de pirido (1, 2-a)bencimidazol sustituidos en el anillo c-6 utiles en el tratamiento de trastornos del sistema nervioso central. MXPA02001308A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14673199P 1999-08-02 1999-08-02
PCT/US2000/019882 WO2001009132A1 (en) 1999-08-02 2000-07-20 C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Publications (1)

Publication Number Publication Date
MXPA02001308A true MXPA02001308A (es) 2004-07-16

Family

ID=22518751

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02001308A MXPA02001308A (es) 1999-08-02 2000-07-20 Derivados de pirido (1, 2-a)bencimidazol sustituidos en el anillo c-6 utiles en el tratamiento de trastornos del sistema nervioso central.

Country Status (12)

Country Link
US (1) US6358946B1 (es)
EP (1) EP1200433B1 (es)
JP (1) JP2003506373A (es)
AR (1) AR025008A1 (es)
AT (1) ATE321044T1 (es)
AU (1) AU779686B2 (es)
CA (1) CA2391766A1 (es)
DE (1) DE60026848T2 (es)
ES (1) ES2260034T3 (es)
MX (1) MXPA02001308A (es)
TW (1) TWI261590B (es)
WO (1) WO2001009132A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL403149A1 (pl) 2013-03-14 2014-09-15 Celon Pharma Spółka Akcyjna Nowe związki pochodne pirazolilobenzo[d]imidazolu

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3463935B2 (ja) * 1992-08-19 2003-11-05 マクニーラブ・インコーポレーテツド 中枢神経系障害の処置において有用な３−オキソ−ピリド（１，２−▲ａ▼）ベンズイミダゾール−４−カルボキシル及び４−オキソ−アゼピノ（１，２−▲ａ▼）ベンズイミダゾール−５−カルボキシル誘導体
US5521200A (en) 1993-12-30 1996-05-28 Ho; Winston 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders
DE69726749T2 (de) * 1996-10-07 2005-07-21 Ortho-Mcneil Pharmaceutical, Inc. 5-heteroatom-alkyl substituierte 3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid derivate zur behandlung zentral nervöser system störungen
US5922731A (en) * 1997-06-30 1999-07-13 Ortho Pharmaceutical Corporation 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders
WO1999018105A1 (en) * 1997-10-07 1999-04-15 Ortho-Mcneil Pharmaceutical, Inc. Dipyridoimidazolderivatives useful in treating central nervous system disorders
AU2653499A (en) 1998-02-04 1999-08-23 Neurogen Corporation Oxo-dipyridoimidazole-carboxamides: gaba brain receptor ligands
AU5691199A (en) 1998-08-25 2000-03-14 Neurogen Corporation Oxo-pyridoimidazole-carboxamides: gaba brain receptor ligands

Also Published As

Publication number Publication date
TWI261590B (en) 2006-09-11
DE60026848T2 (de) 2006-11-16
JP2003506373A (ja) 2003-02-18
US6358946B1 (en) 2002-03-19
EP1200433B1 (en) 2006-03-22
DE60026848D1 (de) 2006-05-11
WO2001009132A1 (en) 2001-02-08
AR025008A1 (es) 2002-11-06
AU6228900A (en) 2001-02-19
AU779686B2 (en) 2005-02-03
ES2260034T3 (es) 2006-11-01
CA2391766A1 (en) 2001-02-08
EP1200433A1 (en) 2002-05-02
ATE321044T1 (de) 2006-04-15

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