DE60026848D1 - C-6 ringsubstituierte pyridoä1,2-aübenzimidazolderivate zur behandlung von störungen des zentralen nervensystems - Google Patents

C-6 ringsubstituierte pyridoä1,2-aübenzimidazolderivate zur behandlung von störungen des zentralen nervensystems

Info

Publication number
DE60026848D1
DE60026848D1 DE60026848T DE60026848T DE60026848D1 DE 60026848 D1 DE60026848 D1 DE 60026848D1 DE 60026848 T DE60026848 T DE 60026848T DE 60026848 T DE60026848 T DE 60026848T DE 60026848 D1 DE60026848 D1 DE 60026848D1
Authority
DE
Germany
Prior art keywords
pyridoa1
zimidazole
derivatives
ring
nervous system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60026848T
Other languages
English (en)
Other versions
DE60026848T2 (de
Inventor
B Reitz
O Nortey
Pauline Sanfilippo
K Scott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
Ortho McNeil Pharmaceutical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho McNeil Pharmaceutical Inc filed Critical Ortho McNeil Pharmaceutical Inc
Publication of DE60026848D1 publication Critical patent/DE60026848D1/de
Application granted granted Critical
Publication of DE60026848T2 publication Critical patent/DE60026848T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE60026848T 1999-08-02 2000-07-20 C-6 ringsubstituierte pyridoä1,2-aübenzimidazolderivate zur behandlung von störungen des zentralen nervensystems Expired - Lifetime DE60026848T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14673199P 1999-08-02 1999-08-02
US146731 1999-08-02
PCT/US2000/019882 WO2001009132A1 (en) 1999-08-02 2000-07-20 C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Publications (2)

Publication Number Publication Date
DE60026848D1 true DE60026848D1 (de) 2006-05-11
DE60026848T2 DE60026848T2 (de) 2006-11-16

Family

ID=22518751

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60026848T Expired - Lifetime DE60026848T2 (de) 1999-08-02 2000-07-20 C-6 ringsubstituierte pyridoä1,2-aübenzimidazolderivate zur behandlung von störungen des zentralen nervensystems

Country Status (12)

Country Link
US (1) US6358946B1 (de)
EP (1) EP1200433B1 (de)
JP (1) JP2003506373A (de)
AR (1) AR025008A1 (de)
AT (1) ATE321044T1 (de)
AU (1) AU779686B2 (de)
CA (1) CA2391766A1 (de)
DE (1) DE60026848T2 (de)
ES (1) ES2260034T3 (de)
MX (1) MXPA02001308A (de)
TW (1) TWI261590B (de)
WO (1) WO2001009132A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL403149A1 (pl) 2013-03-14 2014-09-15 Celon Pharma Spółka Akcyjna Nowe związki pochodne pirazolilobenzo[d]imidazolu

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004532A1 (en) * 1992-08-19 1994-03-03 Mcneilab, Inc. 3-oxo-pyrido(1,2-a^_)benzimidazole-4-carboxyl and 4-oxo-azepino(1,2-a^_)benzimidazole-5-carboxyl derivatives useful in treating central nervous system disorders
US5521200A (en) 1993-12-30 1996-05-28 Ho; Winston 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders
NZ335060A (en) * 1996-10-07 2000-05-26 Ortho Mcneil Pharm Inc 5-heteroatom containing alkyl substituted-3-oxo-pyrido[1,2-a]benzimidazole-4-carboxamide derivatives and medicaments useful in treating central nervous system disorders
US5922731A (en) 1997-06-30 1999-07-13 Ortho Pharmaceutical Corporation 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders
PT1023291E (pt) * 1997-10-07 2004-09-30 Ortho Mcneil Pharm Inc Derivados de dipiridoimidazole uteis no tratamento de desordens do sistema nervoso central
WO1999040092A1 (en) 1998-02-04 1999-08-12 Neurogen Corporation Oxo-dipyridoimidazole-carboxamides: gaba brain receptor ligands
CA2341531A1 (en) 1998-08-25 2000-03-02 Neurogen Corporation Oxo-pyridoimidazole-carboxamides: gaba brain receptor ligands

Also Published As

Publication number Publication date
AU6228900A (en) 2001-02-19
EP1200433A1 (de) 2002-05-02
AR025008A1 (es) 2002-11-06
MXPA02001308A (es) 2004-07-16
TWI261590B (en) 2006-09-11
CA2391766A1 (en) 2001-02-08
JP2003506373A (ja) 2003-02-18
WO2001009132A1 (en) 2001-02-08
ATE321044T1 (de) 2006-04-15
US6358946B1 (en) 2002-03-19
AU779686B2 (en) 2005-02-03
ES2260034T3 (es) 2006-11-01
DE60026848T2 (de) 2006-11-16
EP1200433B1 (de) 2006-03-22

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DE60026848D1 (de) C-6 ringsubstituierte pyridoä1,2-aübenzimidazolderivate zur behandlung von störungen des zentralen nervensystems

Legal Events

Date Code Title Description
8364 No opposition during term of opposition