MXPA01007033A - Heterociclos funcionalizados como moduladores de receptores de quimiocinas. - Google Patents
Heterociclos funcionalizados como moduladores de receptores de quimiocinas.Info
- Publication number
- MXPA01007033A MXPA01007033A MXPA01007033A MXPA01007033A MXPA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A MX PA01007033 A MXPA01007033 A MX PA01007033A
- Authority
- MX
- Mexico
- Prior art keywords
- chemokine receptor
- receptor modulators
- functionalized heterocycles
- heterocycles
- functionalized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11565499P | 1999-01-13 | 1999-01-13 | |
| PCT/US1999/030434 WO2000042045A2 (en) | 1999-01-13 | 1999-12-20 | Functionalized heterocycles as chemokine receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA01007033A true MXPA01007033A (es) | 2003-07-21 |
Family
ID=22362668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA01007033A MXPA01007033A (es) | 1999-01-13 | 1999-12-20 | Heterociclos funcionalizados como moduladores de receptores de quimiocinas. |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1144415A2 (ja) |
| JP (1) | JP2002534526A (ja) |
| KR (1) | KR20010086166A (ja) |
| CN (1) | CN1344270A (ja) |
| AP (1) | AP2001002228A0 (ja) |
| AU (1) | AU1940900A (ja) |
| BR (1) | BR9916905A (ja) |
| CA (1) | CA2372197A1 (ja) |
| CZ (1) | CZ20012502A3 (ja) |
| EA (1) | EA200100774A1 (ja) |
| HK (1) | HK1044539A1 (ja) |
| HU (1) | HUP0202932A3 (ja) |
| IL (1) | IL144289A0 (ja) |
| MX (1) | MXPA01007033A (ja) |
| NO (1) | NO20013456L (ja) |
| OA (1) | OA11820A (ja) |
| PL (1) | PL349348A1 (ja) |
| SK (1) | SK9972001A3 (ja) |
| WO (1) | WO2000042045A2 (ja) |
| ZA (1) | ZA200106592B (ja) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002072549A1 (en) * | 2001-03-12 | 2002-09-19 | Millennium Pharmaceuticals, Inc. | Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor |
| AU2002303094B2 (en) * | 2001-03-29 | 2006-11-23 | Eli Lilly And Company | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor |
| WO2003035650A1 (fr) * | 2001-09-25 | 2003-05-01 | Takeda Chemical Industries, Ltd. | Inhibiteur d'entree |
| BRPI0408332A (pt) | 2003-03-14 | 2006-03-21 | Ono Pharmaceutical Co | derivados heterocìclicos contendo nitrogênio e medicamentos contendo os mesmos como ingrediente ativo |
| US7498323B2 (en) | 2003-04-18 | 2009-03-03 | Ono Pharmaceuticals Co., Ltd. | Spiro-piperidine compounds and medicinal use thereof |
| CN101775013A (zh) | 2004-09-13 | 2010-07-14 | 小野药品工业株式会社 | 含氮杂环衍生物及含有其作为活性成分的药物 |
| WO2006129679A1 (ja) | 2005-05-31 | 2006-12-07 | Ono Pharmaceutical Co., Ltd. | スピロピペリジン化合物およびその医薬用途 |
| US7915286B2 (en) | 2005-09-16 | 2011-03-29 | Ranbaxy Laboratories Limited | Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors |
| PL1942108T3 (pl) | 2005-10-28 | 2014-03-31 | Ono Pharmaceutical Co | Związek zawierający grupę zasadową i jego zastosowanie |
| ES2407115T3 (es) | 2005-11-18 | 2013-06-11 | Ono Pharmaceutical Co., Ltd. | Compuesto que contiene un grupo básico y uso del mismo |
| WO2007095561A2 (en) * | 2006-02-15 | 2007-08-23 | Allergan, Inc. | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor antagonist biological activity |
| CN101460458A (zh) | 2006-02-15 | 2009-06-17 | 阿勒根公司 | 具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物 |
| WO2007105637A1 (ja) | 2006-03-10 | 2007-09-20 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
| JP5257068B2 (ja) | 2006-05-16 | 2013-08-07 | 小野薬品工業株式会社 | 保護されていてもよい酸性基を含有する化合物およびその用途 |
| EA016633B1 (ru) * | 2006-05-23 | 2012-06-29 | Общество С Ограниченной Ответственностью "Инновационная Фармацевтика" | Замещенные индолы, способ их получения и применения |
| EP2055705A4 (en) | 2006-07-31 | 2014-08-20 | Ono Pharmaceutical Co | COMPOUND WITH A CYCLIC GROUP BOUND BY A SPIRO BINDING THEREOF AND APPLY THEREOF |
| US8524917B2 (en) | 2007-01-11 | 2013-09-03 | Allergan, Inc. | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity |
| KR20090101307A (ko) * | 2007-01-11 | 2009-09-24 | 알러간, 인코포레이티드 | 스핑고신-1-포스페이트(ｓ1ｐ) 수용체 길항제 생물학적 활성을 갖는 6-치환된 인돌-3-카르복실산 아미드 화합물 |
| WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
| EP2569301A1 (en) | 2010-05-12 | 2013-03-20 | Abbvie Inc. | Indazole inhibitors of kinase |
| EP2741777B1 (en) | 2011-08-12 | 2017-01-18 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| JO3459B1 (ar) | 2012-09-09 | 2020-07-05 | H Lundbeck As | تركيبات صيدلانية لعلاج مرض الزهايمر |
| CN104193669B (zh) * | 2014-08-01 | 2016-12-07 | 大连理工大学 | 一类阿比朵尔类似物或其盐、其制备方法及应用 |
| WO2016112088A1 (en) * | 2015-01-06 | 2016-07-14 | Spero Therapeutics, Inc. | Aryloxyacetylindoles and analogs as antibiotic tolerance inhibitors |
| CN110256324A (zh) * | 2019-06-13 | 2019-09-20 | 苏州莱安医药化学技术有限公司 | 一种2-甲基-5-羟基吲哚的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3549641A (en) * | 1966-06-28 | 1970-12-22 | Warner Lambert Pharmaceutical | Pyrano pyridines and process for their production |
| US3518258A (en) * | 1967-05-09 | 1970-06-30 | Warner Lambert Pharmaceutical | Pyrano(3,2-i)quinolizine and process for the production |
| US3565903A (en) * | 1967-11-24 | 1971-02-23 | Warner Lambert Pharmaceutical | Pyrano(2,3-b)quinolines and process for their production |
| US5635510A (en) * | 1993-05-06 | 1997-06-03 | Merrell Pharmaceuticals Inc. | Substituted pyrrolidin-3-yl-alkyl-piperidines |
| HRP960352A2 (en) * | 1996-07-26 | 1998-08-31 | Pliva Pharm & Chem Works | Novel coumarin quinoline carboxylic acids |
| TR199902056T2 (xx) * | 1997-02-26 | 2000-01-21 | Pfizer Inc. | Heteroaril-Heksanoik asit amid t�revleri. |
| WO1999038514A1 (en) * | 1998-02-02 | 1999-08-05 | Merck & Co., Inc. | Cyclic amine modulators of chemokine receptor activity |
-
1999
- 1999-12-20 BR BR9916905-3A patent/BR9916905A/pt not_active Application Discontinuation
- 1999-12-20 EP EP99963110A patent/EP1144415A2/en not_active Withdrawn
- 1999-12-20 OA OA1200100187A patent/OA11820A/en unknown
- 1999-12-20 WO PCT/US1999/030434 patent/WO2000042045A2/en not_active Application Discontinuation
- 1999-12-20 EA EA200100774A patent/EA200100774A1/ru unknown
- 1999-12-20 SK SK997-2001A patent/SK9972001A3/sk unknown
- 1999-12-20 AU AU19409/00A patent/AU1940900A/en not_active Abandoned
- 1999-12-20 IL IL14428999A patent/IL144289A0/xx unknown
- 1999-12-20 PL PL99349348A patent/PL349348A1/xx not_active Application Discontinuation
- 1999-12-20 HU HU0202932A patent/HUP0202932A3/hu unknown
- 1999-12-20 KR KR1020017008905A patent/KR20010086166A/ko not_active Application Discontinuation
- 1999-12-20 AP APAP/P/2001/002228A patent/AP2001002228A0/en unknown
- 1999-12-20 CZ CZ20012502A patent/CZ20012502A3/cs unknown
- 1999-12-20 JP JP2000593612A patent/JP2002534526A/ja active Pending
- 1999-12-20 CA CA002372197A patent/CA2372197A1/en not_active Abandoned
- 1999-12-20 MX MXPA01007033A patent/MXPA01007033A/es unknown
- 1999-12-20 CN CN99816475A patent/CN1344270A/zh active Pending
-
2001
- 2001-07-12 NO NO20013456A patent/NO20013456L/no not_active Application Discontinuation
- 2001-08-10 ZA ZA200106592A patent/ZA200106592B/en unknown
-
2002
- 2002-08-28 HK HK02106357.2A patent/HK1044539A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1940900A (en) | 2000-08-01 |
| SK9972001A3 (en) | 2002-03-05 |
| EP1144415A2 (en) | 2001-10-17 |
| BR9916905A (pt) | 2002-01-29 |
| JP2002534526A (ja) | 2002-10-15 |
| CZ20012502A3 (cs) | 2002-03-13 |
| KR20010086166A (ko) | 2001-09-08 |
| HK1044539A1 (zh) | 2002-10-25 |
| NO20013456D0 (no) | 2001-07-12 |
| CN1344270A (zh) | 2002-04-10 |
| WO2000042045A3 (en) | 2000-11-09 |
| IL144289A0 (en) | 2002-05-23 |
| AP2001002228A0 (en) | 2001-09-30 |
| EA200100774A1 (ru) | 2002-02-28 |
| WO2000042045A2 (en) | 2000-07-20 |
| HUP0202932A2 (hu) | 2002-12-28 |
| OA11820A (en) | 2005-08-17 |
| HUP0202932A3 (en) | 2003-07-28 |
| PL349348A1 (en) | 2002-07-15 |
| ZA200106592B (en) | 2002-08-12 |
| CA2372197A1 (en) | 2000-07-20 |
| NO20013456L (no) | 2001-09-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA01007033A (es) | Heterociclos funcionalizados como moduladores de receptores de quimiocinas. | |
| ZA200108846B (en) | Glucocorticoid receptor modulators. | |
| HK1052037A1 (en) | Structural member. | |
| ZA200203181B (en) | Positive modulators of nicotinic receptor agonists. | |
| HK1043985A1 (en) | Chemokine receptor binding heterocyclic compounds | |
| MXPA01013362A (es) | Anticuerpos de humano, anti-alfavbeta3 recombinantes, °cidos nucleicos que codifican a los mismos y metodos de uso. | |
| ZA200001665B (en) | Suspension device. | |
| EG24361A (en) | 4-pyrimiding1-n-acy1.l.phenlalanines | |
| ZA200200477B (en) | 2-pyrazolin-5-ones. | |
| ZA200202537B (en) | Pour-on-formulations. | |
| HK1053470A1 (en) | 4-Pyridinyln-acyl-l-phenylalanines. | |
| ZA200203171B (en) | Positive modulators of nicotinic receptor agonists. | |
| HK1030923A1 (en) | Hoist. | |
| MXPA01012165A (es) | Antagonistas ccr3 del receptor de quimiocina. | |
| HK1047184A1 (en) | Eccentricity compensation apparatus. | |
| HK1030590A1 (en) | Crane apparatus. | |
| ZA200108481B (en) | 8A- and 9A-15-membered lactams. | |
| MXPA02000261A (es) | Aminoindanos novedosos. | |
| HK1054382A1 (en) | Substituted pyrroles. | |
| ZA200108129B (en) | Histidine protein-phosphatase. | |
| MXPA01011286A (es) | Derivados de ciclocarbamato como moduladores de receptor de progesterona. | |
| ZA200108207B (en) | Vinylcyclohexane-based polymers. | |
| HUP0200428A3 (en) | Stopper | |
| ZA200204581B (en) | Nitro-sulfobenzamides. | |
| HK1031254A1 (en) | Tachogragh. |