MX9703113A - Metodo y composiciones para la inhibicion de proteina cinasas. - Google Patents
Metodo y composiciones para la inhibicion de proteina cinasas.Info
- Publication number
- MX9703113A MX9703113A MX9703113A MX9703113A MX9703113A MX 9703113 A MX9703113 A MX 9703113A MX 9703113 A MX9703113 A MX 9703113A MX 9703113 A MX9703113 A MX 9703113A MX 9703113 A MX9703113 A MX 9703113A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- independently represents
- protein kinases
- inhibiting protein
- double bond
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Se describe un método para inhibir selectivamente una cinasa, que comprende poner en contacto una composicion que contiene una cinasa con una molécula de formula (I), en donde R1 es H, alquilo inferior, o alcanoílo inferior; R2 es H, alquilo inferior, o alcanoílo inferior; R3 y R4 representan juntos un doble enlace cis o -O- o cada uno de R3 y R4 representan independientemente H o OR; R5 es =O, =S, o -H, -OR R6 y R7 representan juntos un doble enlace o -O- o cada uno de R6 y R7 representan independientemente H o OR; R8 y R9 representan juntos un doble enlace o -O- o cada uno de R8 y R9 representan independientemente H o OR; y cada R representa independientemente H, alquilo inferior, o alcanoílo inferior.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08332597 | 1994-10-28 | ||
| US08/332,597 US5795910A (en) | 1994-10-28 | 1994-10-28 | Method and compositions for inhibiting protein kinases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9703113A true MX9703113A (es) | 1998-06-30 |
| MXPA97003113A MXPA97003113A (es) | 1998-10-30 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| EP0788356A2 (en) | 1997-08-13 |
| PT788356E (pt) | 2002-06-28 |
| US5795910A (en) | 1998-08-18 |
| DK0788356T3 (da) | 2002-03-18 |
| AU4278996A (en) | 1996-05-23 |
| US5728726A (en) | 1998-03-17 |
| EP0788356B1 (en) | 2001-12-12 |
| TW467743B (en) | 2001-12-11 |
| DE69524628T2 (de) | 2002-08-08 |
| JPH10508024A (ja) | 1998-08-04 |
| ES2170172T3 (es) | 2002-08-01 |
| CA2203757A1 (en) | 1996-05-09 |
| CN1165481A (zh) | 1997-11-19 |
| EP0788356B9 (en) | 2002-10-02 |
| US5674892A (en) | 1997-10-07 |
| ATE210439T1 (de) | 2001-12-15 |
| KR970706812A (ko) | 1997-12-01 |
| AU706621B2 (en) | 1999-06-17 |
| DE69524628D1 (de) | 2002-01-24 |
| WO1996013259A2 (en) | 1996-05-09 |
| WO1996013259A3 (en) | 1996-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |