MX9603403A - Tratamiento de diarrea asociada con antibioticos. - Google Patents

Tratamiento de diarrea asociada con antibioticos.

Info

Publication number
MX9603403A
MX9603403A MX9603403A MX9603403A MX9603403A MX 9603403 A MX9603403 A MX 9603403A MX 9603403 A MX9603403 A MX 9603403A MX 9603403 A MX9603403 A MX 9603403A MX 9603403 A MX9603403 A MX 9603403A
Authority
MX
Mexico
Prior art keywords
treatment
associated diarrhea
antibiotic associated
cdad
antibiotic
Prior art date
Application number
MX9603403A
Other languages
English (en)
Other versions
MXPA96003403A (es
MX197129B (es
Inventor
Louis D Heerze
Glen D Armstrong
Original Assignee
Synsorb Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synsorb Biotech Inc filed Critical Synsorb Biotech Inc
Publication of MX9603403A publication Critical patent/MX9603403A/es
Publication of MXPA96003403A publication Critical patent/MXPA96003403A/es
Publication of MX197129B publication Critical patent/MX197129B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals

Abstract

Esta invencion se refiere al tratamiento de diarrea asociados con antibioticos, incluyendo diarrea asociada con Clostridium difficile (CDAD) y colitis pseudomembranosa (PMC), usando composiciones de oligosacáridos que se enlazan a la toxina A de Clostridium difficile. Muy especificamente, la invencion se refiere a la neutralizacion de toxina A de Cloetridium difficile asociada con CDAD.
MX9603403A 1994-02-14 1996-08-13 Tratamiento de diarrea asociada con antibioticos. MX197129B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/195,009 US5484773A (en) 1994-02-14 1994-02-14 Treatment of antibiotic associated diarrhea
US08195009 1994-02-14

Publications (3)

Publication Number Publication Date
MX9603403A true MX9603403A (es) 1998-10-31
MXPA96003403A MXPA96003403A (es) 1999-01-11
MX197129B MX197129B (es) 2000-06-23

Family

ID=22719705

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9603403A MX197129B (es) 1994-02-14 1996-08-13 Tratamiento de diarrea asociada con antibioticos.

Country Status (15)

Country Link
US (2) US5484773A (es)
EP (1) EP0744959B1 (es)
JP (1) JP4122052B2 (es)
KR (1) KR970701064A (es)
CN (1) CN1131070C (es)
AT (1) ATE267614T1 (es)
AU (1) AU698275B2 (es)
CA (1) CA2181359C (es)
DE (1) DE69533084T2 (es)
IL (1) IL112428A (es)
MX (1) MX197129B (es)
NO (1) NO963378L (es)
NZ (1) NZ279180A (es)
WO (1) WO1995021628A1 (es)
ZA (1) ZA95630B (es)

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ATE198991T1 (de) * 1991-10-18 2001-02-15 Synsorb Biotech Inc Behandlung bakterieller dysenterie
DE4428056A1 (de) * 1994-07-29 1996-02-08 Schering Ag Verwendung von Mikropartikelpräparationen zur Eliminierung gelöster, nicht nierengängiger Substanzen aus dem Blut
US6140045A (en) * 1995-03-10 2000-10-31 Meso Scale Technologies Multi-array, multi-specific electrochemiluminescence testing
US5661131A (en) * 1995-06-05 1997-08-26 Synsorb Biotech, Inc. Treatment of cholera
US5627163A (en) * 1995-06-05 1997-05-06 Synsorb Biotech, Inc. Treatment of traveller's diarrhea
US5811409A (en) * 1995-06-05 1998-09-22 Synsorb Biotech, Inc. Treatment of cholera
US5637576A (en) * 1995-06-05 1997-06-10 Synsorb Biotech, Inc. Treatment of traveller's diarrhea
US5736533A (en) * 1995-06-07 1998-04-07 Neose Technologies, Inc. Bacterial inhibition with an oligosaccharide compound
US6069137A (en) * 1996-03-11 2000-05-30 Synsorb Biotech, Inc. Treatment of traveller's diarrhea
US5891860A (en) * 1996-03-11 1999-04-06 Synsorb Biotech, Inc. Treatment of traveller's diarrhea
JPH107575A (ja) * 1996-06-21 1998-01-13 Synsorb Biotec Inc 細菌性赤痢の処置
US5846943A (en) * 1996-11-08 1998-12-08 Synsorb Biotech, Inc. Solid support matricles containing a toxin binding oligosaccharide
US6013634A (en) * 1996-11-08 2000-01-11 Synsorb Biotech, Inc. Solid support matrices containing a toxin binding oligosaccharide
US5932554A (en) * 1996-11-14 1999-08-03 Synsorb Biotech, Inc. 1-galactose derivatives
US6087339A (en) * 1996-11-14 2000-07-11 Synsorb Biotech, Inc. Saccharide derivatives
US6063769A (en) * 1996-11-14 2000-05-16 Synsorb Biotech, Inc. 1-thiogalactose derivatives
US5968907A (en) * 1996-11-14 1999-10-19 Synsorb Biotech, Inc. 1-thiogalactose derivatives
US5965719A (en) * 1996-11-15 1999-10-12 Sunsorb Biotech, Inc. Combinatorial synthesis of carbohydrate libraries
EP0938492A1 (en) * 1996-11-15 1999-09-01 SYNSORB Biotech Inc. Combinatorial synthesis of carbohydrate libraries
US6096725A (en) * 1997-07-02 2000-08-01 Neose Technologies, Inc. Methods of using αGal oligosaccharides as immune system targeting agents
US20020019991A1 (en) * 1998-04-30 2002-02-14 Abbott Laboratories Compositions containing an alpha 1,2-fucose linkage and uses thereof
US6174867B1 (en) 1998-05-08 2001-01-16 Synsorb Biotech, Inc. 1-galactose derivatives having a carbon- or nitrogen-containing aglycon linkage
US6358930B1 (en) * 1998-05-28 2002-03-19 Synsorb Biotech Inc. Treatment of C. difficile toxin B associated conditions
US6013635A (en) * 1998-05-28 2000-01-11 Synsorb Biotech, Inc. Treatment of C. difficile toxin B associated conditions
US6291435B1 (en) 1999-03-04 2001-09-18 The Governs Of The University Of Alberta Treatment of diarrhea caused by enteropathogenic Escherichia coli
US6270755B1 (en) 1999-05-13 2001-08-07 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders
US6290946B1 (en) * 1999-05-13 2001-09-18 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders and antibacterial agents
CA2314494A1 (en) 2000-05-02 2001-11-02 Geltex Pharmaceuticals, Inc. Anionic polymers as species specific antibacterial agents
US6596707B2 (en) * 2001-05-24 2003-07-22 Abbott Laboratories Monovalent saccharides and uses thereof
CN100411625C (zh) * 2002-07-22 2008-08-20 基酶有限公司 聚(钾和钠的苯乙烯苯磺酸盐),其制备及其用途
US7682631B2 (en) * 2003-10-01 2010-03-23 Clemson University Adhesin-specific nanoparticles and process for using same
MXPA06006392A (es) * 2003-12-05 2007-03-15 Childrens Hosp Medical Center Composiciones de oligosacaridos y uso de estas en el tratamiento de infecciones.
AU2005295708A1 (en) * 2004-10-13 2006-04-27 Relypsa, Inc. Pharmaceutical compositions comprising a toxin-binding oligosaccharide and a polymeric particle
US20060078534A1 (en) * 2004-10-13 2006-04-13 Dominique Charmot Toxin binding compositions
BRPI0610683B8 (pt) * 2005-05-18 2021-05-25 Hopitaux Paris Assist Publique aplicação colônica de absorventes
US7915235B2 (en) * 2006-03-20 2011-03-29 Brian Dieckgraefe High affinity ligands bind to clostridium difficile toxin A
WO2007114683A1 (en) * 2006-03-30 2007-10-11 N.V. Nutricia Milk oligosaccharides for stimulating the immune system
US8048413B2 (en) * 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
US20080041643A1 (en) * 2006-08-17 2008-02-21 Khalife Tony N Wind-power vehicle aka WPV
US7871785B2 (en) 2007-09-07 2011-01-18 Children's Hospital Medical Center Use of secretor, Lewis and sialyl antigen levels in clinical samples as predictors of risk for disease
JP2012532195A (ja) 2009-07-06 2012-12-13 チルドレンズ ホスピタル メディカル センター 乳オリゴ糖による炎症の阻害
WO2014130789A1 (en) 2013-02-21 2014-08-28 Children's Hospital Medical Center Use of glycans and glycosyltransferases for diagnosing/monitoring inflammatory bowel disease
EP3288389A4 (en) 2015-04-28 2018-10-10 Children's Hospital Medical Center Use of oligosaccharide compositions to enhance weight gain
CN108977497A (zh) * 2018-06-12 2018-12-11 深圳市领治医学科技有限公司 一种采集和保存人痕量粪便样本的方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1544908A (en) * 1975-07-08 1979-04-25 Chembiomed Ltd Artificial oligosaccharide antigenic determinants
US4362720A (en) * 1977-04-14 1982-12-07 Chembiomed Ltd. Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals
DE2857790C2 (de) * 1977-04-14 1983-12-22 Chembiomed Ltd., Edmonton, Alberta Verfahren zur Herstellung von O-geschützten 2-Azido-2-desoxy-glycosylhalogeniden, einige derartige Verbindungen als solche und deren Verwendung
US4713240A (en) * 1985-04-04 1987-12-15 Research Corporation Vaccines based on insoluble supports
US4863852A (en) * 1985-07-03 1989-09-05 Virginia Tech Intellectual Properties, Inc. Method of detecting, isolating and purifying clostridium difficile toxin A and its receptors
US5079353A (en) * 1987-12-02 1992-01-07 Chembiomed, Ltd. Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
US5098826A (en) * 1990-03-09 1992-03-24 Virginia Tech Intellectual Properties, Inc. Detection, isolation and purification of Clostridium difficile toxin A with toxin receptors
US5266315A (en) * 1990-05-07 1993-11-30 Kabushiki Kaisha Miyarisan Seibutsu Igaku Kenkyusho Composite for Clostridium difficile diarrhea and pseudomembranous colitis
ATE198991T1 (de) * 1991-10-18 2001-02-15 Synsorb Biotech Inc Behandlung bakterieller dysenterie

Also Published As

Publication number Publication date
CA2181359C (en) 2001-07-03
CA2181359A1 (en) 1995-08-17
CN1140415A (zh) 1997-01-15
IL112428A (en) 1999-08-17
NO963378D0 (no) 1996-08-13
IL112428A0 (en) 1995-03-30
NZ279180A (en) 1997-10-24
KR970701064A (en) 1997-03-17
AU698275B2 (en) 1998-10-29
DE69533084T2 (de) 2005-06-09
EP0744959A1 (en) 1996-12-04
ATE267614T1 (de) 2004-06-15
DE69533084D1 (de) 2004-07-01
US5635606A (en) 1997-06-03
ZA95630B (en) 1995-10-05
JPH09508631A (ja) 1997-09-02
WO1995021628A1 (en) 1995-08-17
EP0744959B1 (en) 2004-05-26
JP4122052B2 (ja) 2008-07-23
CN1131070C (zh) 2003-12-17
MX197129B (es) 2000-06-23
AU1572795A (en) 1995-08-29
US5484773A (en) 1996-01-16
NO963378L (no) 1996-08-13

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