BRPI0610683B8 - aplicação colônica de absorventes - Google Patents
aplicação colônica de absorventesInfo
- Publication number
- BRPI0610683B8 BRPI0610683B8 BRPI0610683A BRPI0610683A BRPI0610683B8 BR PI0610683 B8 BRPI0610683 B8 BR PI0610683B8 BR PI0610683 A BRPI0610683 A BR PI0610683A BR PI0610683 A BRPI0610683 A BR PI0610683A BR PI0610683 B8 BRPI0610683 B8 BR PI0610683B8
- Authority
- BR
- Brazil
- Prior art keywords
- colon
- absorbent
- absorbents
- application
- application systems
- Prior art date
Links
- 230000002745 absorbent Effects 0.000 title abstract 8
- 239000002250 absorbent Substances 0.000 title abstract 8
- 230000000112 colonic effect Effects 0.000 title abstract 3
- 210000001072 colon Anatomy 0.000 abstract 5
- 239000002245 particle Substances 0.000 abstract 3
- 235000010987 pectin Nutrition 0.000 abstract 3
- 229920001277 pectin Polymers 0.000 abstract 3
- 239000001814 pectin Substances 0.000 abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 239000011324 bead Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 230000002351 pectolytic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 108700012359 toxins Proteins 0.000 abstract 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68207405P | 2005-05-18 | 2005-05-18 | |
US60/682,074 | 2005-05-18 | ||
PCT/EP2006/005629 WO2006122835A1 (en) | 2005-05-18 | 2006-05-18 | Colonic delivery of adsorbents |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0610683A2 BRPI0610683A2 (pt) | 2010-07-20 |
BRPI0610683B1 BRPI0610683B1 (pt) | 2020-09-08 |
BRPI0610683B8 true BRPI0610683B8 (pt) | 2021-05-25 |
Family
ID=36974012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0610683A BRPI0610683B8 (pt) | 2005-05-18 | 2006-05-18 | aplicação colônica de absorventes |
Country Status (12)
Country | Link |
---|---|
US (1) | US8106000B2 (pt) |
EP (1) | EP1883396B1 (pt) |
JP (1) | JP2008540602A (pt) |
CN (1) | CN101257892B (pt) |
AU (1) | AU2006249100B2 (pt) |
BR (1) | BRPI0610683B8 (pt) |
CA (1) | CA2608505C (pt) |
DK (1) | DK1883396T3 (pt) |
ES (1) | ES2429095T3 (pt) |
PL (1) | PL1883396T3 (pt) |
PT (1) | PT1883396E (pt) |
WO (1) | WO2006122835A1 (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8048413B2 (en) | 2006-05-17 | 2011-11-01 | Helene Huguet | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
US8932634B2 (en) * | 2006-06-15 | 2015-01-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Hydrocolloid carrier beads with inert filler material |
JP2010510196A (ja) * | 2006-11-17 | 2010-04-02 | ダ・ボルテラ | オイドラギット被覆を施した亜鉛/ペクチンビーズを使用する結腸送達 |
US20080124279A1 (en) * | 2006-11-17 | 2008-05-29 | Antoine Andremont | Colonic delivery using Zn/pectin beads with a Eudragit coating |
US8273376B2 (en) | 2006-11-17 | 2012-09-25 | Da Volterra | Colonic delivery of metallo-dependent enzymes |
FI119678B (fi) * | 2006-11-28 | 2009-02-13 | Ipsat Therapies Oy | Beta-laktamaasin käyttö |
US20100239682A1 (en) * | 2007-09-17 | 2010-09-23 | Antoine Andremont | Colonic delivery of antimicrobial agents |
FR2950252B1 (fr) | 2009-09-23 | 2012-01-20 | Centre Nat Rech Scient | Forme galenique capable d'adsorber de maniere specifique les molecules indesirables |
CZ302789B6 (cs) | 2009-11-25 | 2011-11-09 | Zentiva, K. S. | Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva |
KR101820374B1 (ko) | 2010-02-23 | 2018-01-19 | 다 볼떼라 | 장 내 흡착제의 경구 전달을 위한 제형 |
FI20105572A0 (fi) | 2010-05-24 | 2010-05-24 | Prevab R Lcc | Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt |
RU2678124C2 (ru) | 2014-04-17 | 2019-01-23 | Синтесик Байолоджикс, Инк. | Бета-лактамазы с улучшенными свойствами для лечения |
CN106574273B (zh) | 2014-08-28 | 2021-07-02 | 合成生物制品有限公司 | β-内酰胺酶的基于大肠杆菌的生产 |
WO2016057744A1 (en) | 2014-10-08 | 2016-04-14 | Synthetic Biologics, Inc. | Beta-lactamase formulations and uses thereof |
EP3236993B1 (en) | 2014-12-23 | 2023-09-13 | Theriva Biologics, Inc. | Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics |
WO2016137993A1 (en) | 2015-02-23 | 2016-09-01 | Synthetic Biologics, Inc. | Carbapenemases for use with antibiotics for the protection of the intestinal microbiome |
AU2016229976B2 (en) | 2015-03-06 | 2021-11-11 | Theriva Biologics, Inc. | Safe and effective beta-lactamase dosing for microbiome protection |
US20180303867A1 (en) * | 2015-10-06 | 2018-10-25 | Da Volterra | Suppression or reduction of the pathogenicity or virulence of a clostridium bacteria |
JP2021533150A (ja) | 2018-08-05 | 2021-12-02 | ダ・ヴォルテッラ | 移植片対宿主病の治療のための組成物 |
BR112021002106A2 (pt) | 2018-08-05 | 2021-06-01 | Da Volterra | método para aprimorar a eficácia de agente anticâncer |
CN110051688B (zh) * | 2019-05-07 | 2022-01-14 | 西北师范大学 | 半胱氨酸接枝凹凸棒石复合材料在制备解毒剂中的应用 |
CN111450049B (zh) * | 2020-05-11 | 2021-06-25 | 中国药科大学 | 一种具有结肠特异性递送的微米水凝胶制备方法 |
WO2022084550A1 (en) | 2020-10-23 | 2022-04-28 | Da Volterra | Compositions for use in the treatment or prevention of dysbiosis |
WO2022090433A1 (en) | 2020-10-30 | 2022-05-05 | Da Volterra | Method for the manufacture of an adsorbent formulation |
WO2022101267A2 (en) | 2020-11-12 | 2022-05-19 | Da Volterra | Compositions for delivery of an adsorbent |
WO2022101269A1 (en) | 2020-11-13 | 2022-05-19 | Da Volterra | Formulations and dosage regimen for oral delivery of adsorbents in the gut |
CN112451541A (zh) * | 2020-12-25 | 2021-03-09 | 刘长德 | 一种防治犬猫腹泻的组合物 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2437878A1 (de) | 1974-07-26 | 1976-02-12 | Sandoz Ag | Ueberzogene aktivkohleteilchen |
JPH03120227A (ja) | 1989-10-02 | 1991-05-22 | Shigeo Ochi | 飲食物消化分解産物吸収抑制剤 |
US5484773A (en) * | 1994-02-14 | 1996-01-16 | Alberta Research Council | Treatment of antibiotic associated diarrhea |
US5929051A (en) * | 1998-05-13 | 1999-07-27 | Carrington Laboratories, Inc. | Aloe pectins |
CN100358509C (zh) | 1998-09-28 | 2008-01-02 | 沃纳-兰伯特公司 | 采用hpmc胶囊进行肠和结肠传递 |
US6706287B2 (en) | 2001-05-15 | 2004-03-16 | Kibow Biotech Inc. | Prebiotic and probiotic compositions and methods for their use in gut-based therapies |
US6706263B2 (en) | 1999-04-30 | 2004-03-16 | Kibow Biotech Inc. | Composition for alleviating symptoms of uremia in patients |
US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
US6991807B2 (en) | 2000-02-24 | 2006-01-31 | Advancis Pharmaceutical, Corp. | Antibiotic composition |
DE10013029A1 (de) | 2000-03-17 | 2001-09-20 | Roehm Gmbh | Mehrschichtige Arzneiform für die Colonfreigabe |
CN1326745A (zh) * | 2000-06-01 | 2001-12-19 | 翟永功 | 蒙脱石为胃肠道药物的成份 |
US7105174B2 (en) | 2000-10-13 | 2006-09-12 | Advancis Pharmaceutical Corporation | Multiple-delayed release anti-neoplastic product, use and formulation thereof |
US7074417B2 (en) | 2000-10-13 | 2006-07-11 | Advancis Pharmaceutical Corporation | Multiple-delayed release anti-viral product, use and formulation thereof |
US7157095B2 (en) | 2000-10-13 | 2007-01-02 | Advancis Pharmaceutical Corporation | Multiple-delayed release antifungal product, use and formulation thereof |
EP1248599B1 (de) | 2001-01-31 | 2007-12-05 | Evonik Röhm GmbH | Multipartikuläre arzneiform, enthaltend mindestens zwei unterschiedlich überzogene pelletformen |
JP2002308786A (ja) * | 2001-04-12 | 2002-10-23 | Oto Corporation:Kk | 食物繊維で包括されたカーボン粒入りゼリーの製造法 |
EP1435922A1 (de) | 2001-10-15 | 2004-07-14 | Röhm GmbH & Co. KG | Verwendung eines copolymeren zur herstellung einer arzneiform, die als wirkstoff ein peptid oder protein enthält |
WO2003086344A1 (en) | 2001-12-20 | 2003-10-23 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
WO2003075852A2 (en) | 2002-03-07 | 2003-09-18 | Advancis Pharmaceuticals Corporation | Antibiotic composition |
DE10214002A1 (de) | 2002-03-27 | 2003-10-09 | Roehm Gmbh | Pharmazeutische Formulierung für den Wirkstoff Budesonid |
US7317001B2 (en) | 2002-06-06 | 2008-01-08 | Oscient Pharmaceuticals Corporation | Use of ramoplanin to treat diseases associated with the use of antibiotics |
FR2843302B1 (fr) * | 2002-08-09 | 2004-10-22 | Centre Nat Rech Scient | Forme galenique pour la delivrance colique de principes actifs |
SE0203065D0 (sv) | 2002-10-16 | 2002-10-16 | Diabact Ab | Gastric acid secretion inhibiting composition |
DE10250543A1 (de) | 2002-10-29 | 2004-05-19 | Röhm GmbH & Co. KG | Mehrschichtige Arzneiform |
DE10260921A1 (de) | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln |
DE10332160A1 (de) | 2003-07-15 | 2005-02-03 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
AR045068A1 (es) | 2003-07-23 | 2005-10-12 | Univ Missouri | Formulacion de liberacion inmediata de composiciones farmaceuticas |
US20050244490A1 (en) | 2003-12-09 | 2005-11-03 | Michael Otto | Dosing methods for beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine antiviral therapy |
DK1566173T3 (da) | 2004-02-20 | 2006-12-27 | Mattern Udo | Farmaceutisk sammensætning til oral anvendelse og fremgangsmåde til fremstilling deraf |
US8048413B2 (en) | 2006-05-17 | 2011-11-01 | Helene Huguet | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
-
2006
- 2006-05-18 CA CA2608505A patent/CA2608505C/en active Active
- 2006-05-18 WO PCT/EP2006/005629 patent/WO2006122835A1/en active Application Filing
- 2006-05-18 DK DK06743150.2T patent/DK1883396T3/da active
- 2006-05-18 AU AU2006249100A patent/AU2006249100B2/en not_active Ceased
- 2006-05-18 JP JP2008511657A patent/JP2008540602A/ja active Pending
- 2006-05-18 BR BRPI0610683A patent/BRPI0610683B8/pt not_active IP Right Cessation
- 2006-05-18 CN CN2006800231175A patent/CN101257892B/zh not_active Expired - Fee Related
- 2006-05-18 PL PL06743150T patent/PL1883396T3/pl unknown
- 2006-05-18 EP EP06743150.2A patent/EP1883396B1/en active Active
- 2006-05-18 US US11/920,713 patent/US8106000B2/en not_active Expired - Fee Related
- 2006-05-18 PT PT67431502T patent/PT1883396E/pt unknown
- 2006-05-18 ES ES06743150T patent/ES2429095T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
CN101257892A (zh) | 2008-09-03 |
WO2006122835A1 (en) | 2006-11-23 |
BRPI0610683B1 (pt) | 2020-09-08 |
AU2006249100B2 (en) | 2012-01-19 |
WO2006122835B1 (en) | 2007-04-12 |
US20090324568A1 (en) | 2009-12-31 |
BRPI0610683A2 (pt) | 2010-07-20 |
ES2429095T3 (es) | 2013-11-13 |
EP1883396A1 (en) | 2008-02-06 |
CN101257892B (zh) | 2013-01-02 |
PT1883396E (pt) | 2013-10-08 |
DK1883396T3 (da) | 2013-10-07 |
US8106000B2 (en) | 2012-01-31 |
CA2608505C (en) | 2013-12-24 |
CA2608505A1 (en) | 2006-11-23 |
JP2008540602A (ja) | 2008-11-20 |
AU2006249100A1 (en) | 2006-11-23 |
EP1883396B1 (en) | 2013-07-03 |
PL1883396T3 (pl) | 2014-03-31 |
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Legal Events
Date | Code | Title | Description |
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B25A | Requested transfer of rights approved |
Owner name: DA VOLTERRA (FR) , CENTRE NATIONAL DE LA RECHERCHE |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/09/2020, OBSERVADAS AS CONDICOES LEGAIS. |
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B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
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B25A | Requested transfer of rights approved |
Owner name: DA VOLTERRA (FR) ; ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) ; UNIVERSITE PARIS DIDEROT - PARIS 7 (FR) ; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) ; UNIVERSITE PARIS-SACLAY (FR) |
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B25A | Requested transfer of rights approved |
Owner name: DA VOLTERRA (FR) ; ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (FR) ; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) ; UNIVERSITE PARIS-SACLAY (FR) ; UNIVERSITE DE PARIS (FR) |
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