MX9307555A - Derivados de paclitaxel y formulaciones farmaceuticas que los contienen. - Google Patents

Derivados de paclitaxel y formulaciones farmaceuticas que los contienen.

Info

Publication number
MX9307555A
MX9307555A MX9307555A MX9307555A MX9307555A MX 9307555 A MX9307555 A MX 9307555A MX 9307555 A MX9307555 A MX 9307555A MX 9307555 A MX9307555 A MX 9307555A MX 9307555 A MX9307555 A MX 9307555A
Authority
MX
Mexico
Prior art keywords
pharmaceutical formulations
formulations containing
paclitaxel derivatives
pharmaceutically acceptable
paclitaxel
Prior art date
Application number
MX9307555A
Other languages
English (en)
Inventor
Shu-Hui Chen
Vittorio Farina
Gregory Roth
John Kadow
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/128,619 external-priority patent/US5380751A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX9307555A publication Critical patent/MX9307555A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Una formulación farmacéutica, caracterizada porque comprende como uningrediente activo un compuesto, o una sal farmacéuticamente aceptable delmismo, asociada con uno o más portadores, excipientes o diluyentesfarmacéuticamente aceptables para el mismo.
MX9307555A 1992-12-04 1993-12-01 Derivados de paclitaxel y formulaciones farmaceuticas que los contienen. MX9307555A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98576192A 1992-12-04 1992-12-04
US08/128,619 US5380751A (en) 1992-12-04 1993-09-28 6,7-modified paclitaxels

Publications (1)

Publication Number Publication Date
MX9307555A true MX9307555A (es) 1995-01-31

Family

ID=26826766

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9307555A MX9307555A (es) 1992-12-04 1993-12-01 Derivados de paclitaxel y formulaciones farmaceuticas que los contienen.

Country Status (20)

Country Link
EP (1) EP0600517B1 (es)
JP (1) JP3360186B2 (es)
CN (1) CN1049433C (es)
AT (1) ATE195939T1 (es)
AU (1) AU668777B2 (es)
CA (1) CA2109861C (es)
CZ (1) CZ287599B6 (es)
DE (1) DE69329327T2 (es)
DK (1) DK0600517T3 (es)
ES (1) ES2149188T3 (es)
FI (1) FI109795B (es)
GR (1) GR3034686T3 (es)
HU (2) HU222347B1 (es)
IL (1) IL107819A (es)
MX (1) MX9307555A (es)
NO (1) NO305756B1 (es)
NZ (1) NZ250343A (es)
PL (1) PL178135B1 (es)
PT (1) PT600517E (es)
SG (1) SG55014A1 (es)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998656A (en) 1991-09-23 1999-12-07 Florida State University C10 tricyclic taxanes
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State C10 taxane derivatives and pharmaceutical compositions containing them
EP0982301B1 (en) * 1993-06-11 2003-09-10 PHARMACIA & UPJOHN COMPANY Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them
IL127599A (en) * 1994-01-28 2004-06-01 Upjohn Co Process for preparing isotaxol analogs
US5395850A (en) * 1994-03-10 1995-03-07 Bristol-Myers Squibb Company 6,7-epoxy paclitaxels
GB9409131D0 (en) * 1994-05-09 1994-06-29 Erba Carlo Spa Unsaturated taxane compounds
FR2721025B1 (fr) * 1994-06-09 1996-07-12 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2721026B1 (fr) * 1994-06-09 1996-07-12 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5840929A (en) * 1995-04-14 1998-11-24 Bristol-Myers Squibb Company C4 methoxy ether derivatives of paclitaxel
FR2742753B1 (fr) * 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5773461A (en) * 1996-06-06 1998-06-30 Bristol-Myers Squibb Company 7-deoxy-6-substituted paclitaxels
US5635531A (en) * 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
US5977386A (en) * 1996-12-24 1999-11-02 Bristol-Myers Squibb Company 6-thio-substituted paclitaxels
US5902822A (en) * 1997-02-28 1999-05-11 Bristol-Myers Squibb Company 7-methylthiooxomethyl and 7-methylthiodioxomethyl paclitaxels
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US6017935A (en) * 1997-04-24 2000-01-25 Bristol-Myers Squibb Company 7-sulfur substituted paclitaxels
IT1317731B1 (it) * 2000-01-18 2003-07-15 Indena Spa Tassani semisintetici con attivita' antitumorale ed antiangiogenetica.
EP1165549B1 (en) 2000-02-02 2008-04-16 Florida State University Research Foundation, Inc. C7 carbamoyloxy substituted taxanes as antitumor agents
IL145636A0 (en) 2000-02-02 2002-06-30 Univ Florida State Res Found C10 carbonate substituted taxanes as antitumor agents
MXPA01009921A (es) 2000-02-02 2003-08-01 Univ Florida State Res Found Taxanos sustituidos como carbamoiloxilo en c10 como agentes antitumorales.
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
EP1992643A3 (en) 2001-06-20 2008-12-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
EP2143438B1 (en) 2001-09-18 2011-07-13 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumors
NZ533933A (en) 2002-01-02 2008-06-30 Genentech Inc Compositions and methods for the diagnosis and treatment of glioma tumor
KR20040101502A (ko) 2002-04-16 2004-12-02 제넨테크, 인크. 종양의 진단 및 치료 방법 및 이를 위한 조성물
AU2003243400B2 (en) 2002-06-07 2009-10-29 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
NZ596984A (en) 2003-11-17 2013-10-25 Genentech Inc Compositions and methods for the treatment of tumor of hematopoietic origin
GT200500025A (es) * 2004-02-13 2005-09-30 Taxanos sustituidos con esteres de ciclopentilo en c10
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
US7964195B2 (en) 2005-01-07 2011-06-21 Diadexus, Inc. Ovr110 antibody compositions and methods of use
AU2007243946B2 (en) 2006-04-05 2012-11-29 Curis, Inc. Method for using BOC/CDO to modulate hedgehog signaling
US8444971B2 (en) 2006-11-27 2013-05-21 Diadexus, Inc. OVR110 antibody compositions and methods of use
CA2676790A1 (en) 2007-02-22 2008-08-28 Genentech, Inc. Methods for detecting inflammatory bowel disease
NZ583367A (en) 2007-07-16 2012-10-26 Genentech Inc Anti-cd79b antibodies and immunoconjugates and methods of use
CL2008002083A1 (es) 2007-07-16 2008-11-21 Genentech Inc Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico
ES2643239T3 (es) 2008-01-31 2017-11-21 Genentech, Inc. Anticuerpos anti-CD79b e inmunoconjugados y métodos de uso
CA2718567A1 (en) 2008-03-31 2009-12-03 Florida State University Research Foundation, Inc. C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
KR20120057565A (ko) 2009-04-01 2012-06-05 제넨테크, 인크. 항-ＦｃＲＨ５ 항체 및 면역접합체 및 사용 방법
CA2778442A1 (en) 2009-10-22 2011-04-28 Genentech, Inc. Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
TWI537383B (zh) 2009-11-30 2016-06-11 建南德克公司 診斷及治療腫瘤之組合物及方法
CA2787657A1 (en) 2010-02-23 2011-09-01 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
CN102958941A (zh) 2010-05-03 2013-03-06 霍夫曼-拉罗奇有限公司 用于肿瘤诊断和治疗的组合物和方法
CN104650012A (zh) 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物
WO2015116902A1 (en) 2014-01-31 2015-08-06 Genentech, Inc. G-protein coupled receptors in hedgehog signaling
CR20250325A (es) 2018-04-13 2025-08-29 Genentech Inc Formulaciones inmunoconjugadas anti-cd79b estables (divisional expediente 2020-0550)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4876399A (en) * 1987-11-02 1989-10-24 Research Corporation Technologies, Inc. Taxols, their preparation and intermediates thereof
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5015744A (en) * 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
EP0982301B1 (en) * 1993-06-11 2003-09-10 PHARMACIA & UPJOHN COMPANY Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NO934277L (no) 1994-06-06
NO934277D0 (no) 1993-11-26
HU222347B1 (hu) 2003-06-28
IL107819A0 (en) 1994-04-12
DE69329327T2 (de) 2001-04-05
ES2149188T3 (es) 2000-11-01
FI935381A0 (fi) 1993-12-01
AU5212193A (en) 1994-06-16
HUT65640A (en) 1994-07-28
SG55014A1 (en) 1998-12-21
DK0600517T3 (da) 2000-10-30
GR3034686T3 (en) 2001-01-31
HU9303428D0 (en) 1994-04-28
JPH06211823A (ja) 1994-08-02
HU221817B1 (hu) 2003-01-28
CN1094041A (zh) 1994-10-26
EP0600517A1 (en) 1994-06-08
CZ287599B6 (en) 2001-01-17
DE69329327D1 (de) 2000-10-05
CA2109861A1 (en) 1994-06-05
NO305756B1 (no) 1999-07-19
PT600517E (pt) 2000-12-29
ATE195939T1 (de) 2000-09-15
CZ260393A3 (en) 1994-07-13
IL107819A (en) 2000-06-29
FI935381L (fi) 1994-06-05
PL178135B1 (pl) 2000-03-31
PL301305A1 (en) 1994-06-13
NZ250343A (es) 1996-11-26
EP0600517B1 (en) 2000-08-30
JP3360186B2 (ja) 2002-12-24
CA2109861C (en) 1999-03-16
AU668777B2 (en) 1996-05-16
FI109795B (fi) 2002-10-15
CN1049433C (zh) 2000-02-16

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees