MX9303642A - Composiciones enfriadoras con efecto pungente reducido. - Google Patents
Composiciones enfriadoras con efecto pungente reducido.Info
- Publication number
- MX9303642A MX9303642A MX9303642A MX9303642A MX9303642A MX 9303642 A MX9303642 A MX 9303642A MX 9303642 A MX9303642 A MX 9303642A MX 9303642 A MX9303642 A MX 9303642A MX 9303642 A MX9303642 A MX 9303642A
- Authority
- MX
- Mexico
- Prior art keywords
- coolant
- cooling compositions
- compositions
- reduced
- specific type
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q9/00—Preparations for removing hair or for aiding hair removal
- A61Q9/02—Shaving preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención provee composiciones enfriadoras para aplicación tópica a la piel, que pueden dar enfriamiento de larga duración, con poco o reducido efecto pungente para la piel. Las composiciones comprenden una mezcla de un tipo específico de enfriador de carboxiamida acíclica, con un tipo específico de enfriador de p-mentano 3 sustituido, un vehículo acuoso y no más de aproximadamente 30 de alcohol monohídrico de 1 a 6 átomos de carbono.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90021992A | 1992-06-17 | 1992-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9303642A true MX9303642A (es) | 1994-05-31 |
Family
ID=25412181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9303642A MX9303642A (es) | 1992-06-17 | 1993-06-17 | Composiciones enfriadoras con efecto pungente reducido. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6277385B1 (es) |
EP (1) | EP0644749B1 (es) |
AT (1) | ATE156997T1 (es) |
AU (1) | AU4530493A (es) |
BR (1) | BR9306575A (es) |
CA (1) | CA2123794C (es) |
DE (1) | DE69313278T2 (es) |
ES (1) | ES2105293T3 (es) |
GR (1) | GR3025029T3 (es) |
MX (1) | MX9303642A (es) |
WO (1) | WO1993025177A1 (es) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527530A (en) * | 1994-07-08 | 1996-06-18 | The Procter & Gamble Company | Alcoholic moisturizing after shave lotion |
US5449512A (en) * | 1994-08-24 | 1995-09-12 | The Procter & Gamble Company | Anhydrous after shave lotions |
US5698181A (en) * | 1994-12-09 | 1997-12-16 | Warner-Lambert Company | Breath-freshening edible compositions comprising menthol and an N-substituted-P-menthane carboxamide and methods for preparing same |
US5649914A (en) * | 1994-12-22 | 1997-07-22 | Kimberly-Clark Corporation | Toilet training aid |
US5681298A (en) * | 1994-12-22 | 1997-10-28 | Kimberly-Clark Worldwide, Inc. | Toilet training aid creating a temperature change |
AU4928596A (en) * | 1995-03-16 | 1996-10-02 | Procter & Gamble Company, The | Coolant compositions |
US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
US5713131A (en) * | 1995-06-30 | 1998-02-03 | The Gillette Company | Shaving aid composite with a non-volatile cooling agent |
US5725865A (en) * | 1995-08-29 | 1998-03-10 | V. Mane Fils S.A. | Coolant compositions |
US5752529A (en) * | 1996-08-21 | 1998-05-19 | V. Mane Fils S.A. | Tobacco products containing coolant compositions |
US5843466A (en) * | 1995-08-29 | 1998-12-01 | V. Mane Fils S.A. | Coolant compositions |
WO1997007771A1 (fr) * | 1995-08-29 | 1997-03-06 | V. Mane Fils S.A. | Compositions rafraichissantes |
FR2747036B1 (fr) * | 1996-04-05 | 1998-05-15 | Oreal | Composition cosmetique comprenant un polymere fixant et un amidon amphotere |
US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
US5693330A (en) * | 1996-04-25 | 1997-12-02 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing melinamide and a retinoid |
US5747051A (en) * | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
ATE243493T1 (de) * | 1997-03-19 | 2003-07-15 | Koninkl Philips Electronics Nv | Vorrasurwasser |
US7588793B1 (en) | 1998-06-05 | 2009-09-15 | Cadbury Adams Usa, Llc | Enhanced flavoring compositions containing N-ethyl-p-menthane-3-carboxamide and method of making and using same |
JP4873768B2 (ja) * | 1999-08-19 | 2012-02-08 | 久光製薬株式会社 | 経皮吸収促進剤及び経皮吸収型製剤 |
AU776143B2 (en) * | 1999-09-24 | 2004-08-26 | Reckitt Benckiser (Uk) Limited | Skin treatment compositions |
AU2001283312A1 (en) * | 2000-08-11 | 2002-02-25 | The Procter And Gamble Company | Method of providing improved deodorant application to the underarm |
US7344702B2 (en) * | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
EP1496095B1 (en) * | 2002-03-01 | 2006-12-20 | Takasago International Corporation | Refrigerant compositions and uses thereof |
ES2687970T3 (es) | 2002-09-05 | 2018-10-30 | Vanderbilt Royalty Sub L.P. | Composiciones y kits para la eliminación de compuestos irritantes de las superficies corporales |
DE10329361A1 (de) * | 2003-06-30 | 2005-01-27 | Laverana Gmbh | Gleitmittelzusammensetzung |
US20050020600A1 (en) * | 2003-07-23 | 2005-01-27 | Scherer Warren J. | Methods of treating cutaneous flushing using selective alpha-2-adrenergic receptor agonists |
JP5335191B2 (ja) * | 2003-08-22 | 2013-11-06 | デンドレオン コーポレイション | Trp−p8発現に関連する疾患の処置をするための組成物および方法 |
US7482378B2 (en) * | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
AU2005262354B2 (en) * | 2004-07-01 | 2008-10-23 | E-L Management Corp. | Cosmetic compositions and methods for sensory cooling |
JP4964773B2 (ja) | 2004-08-11 | 2012-07-04 | クラフト・フーヅ・グローバル・ブランズ・エルエルシー | 感覚惹起剤組成物及びそれらの送達システム |
US20070148284A1 (en) | 2004-08-25 | 2007-06-28 | Cadbury Adams Usa Llc. | Liquid-filled chewing gum |
US20060067962A1 (en) * | 2004-09-30 | 2006-03-30 | Kimberly-Clark Worldwide, Inc. | Skin cooling compositions |
US20060067961A1 (en) * | 2004-09-30 | 2006-03-30 | Kimberly-Clark Worldwide,Inc. | Skin cooling compositions |
DK1833443T3 (da) * | 2005-01-04 | 2012-01-23 | Teikoku Pharma Usa Inc | Kølende topisk plastersammensætning |
WO2006107723A1 (en) * | 2005-04-01 | 2006-10-12 | Neurogesx, Inc. | Oils of capsaicinoids and methods of making and using the same |
WO2006127935A1 (en) | 2005-05-23 | 2006-11-30 | Cadbury Adams Usa Llc | Taste potentiator compositions and beverages containing same |
EP1940377A4 (en) * | 2005-10-24 | 2010-12-08 | Teikoku Pharma Usa Inc | TOPICAL AEROSPECTIVE COMPOSITIONS OF N, 2,3-TRIMETHYL-2-ISOPROPYLBUTAMIDE AND METHOD OF USE THEREOF |
WO2007073525A2 (en) * | 2005-11-28 | 2007-06-28 | Yvonne Daily | Hot-flash wipes and clothing |
ES2478634T3 (es) | 2005-12-23 | 2014-07-22 | Intercontinental Great Brands Llc | Composiciones que proporcionan sensación de calor para administración oral o dérmica |
EP2001448A2 (en) * | 2006-01-27 | 2008-12-17 | Cadbury Adams USA LLC | Flavor-enhancing compositions, methods of manufacture, and methods of use |
US7772266B2 (en) | 2006-02-15 | 2010-08-10 | Dendreon Corporation | Small-molecule modulators of TRP-P8 activity |
BRPI0707821A2 (pt) | 2006-02-15 | 2011-05-10 | Dendreon Corp | composto, mÉtodos para tratar cÂncer, para induzir apoptose e/ou necrose em uma cÉlula que expressa trp-p8, composiÇço farmacÊutica, mÉtodos para tratar uma doenÇa ou uma condiÇço, para modular a funÇço receptora de trp-p8, uso de um composto , e, mÉtodo para indentificar um agonista de trp-8 |
US20080213440A1 (en) | 2007-03-01 | 2008-09-04 | Cadbury Adams Usa Llc | Non-Aldehyde Cinnamon Flavor and Delivery Systems Therefor |
CN101883499A (zh) * | 2007-11-29 | 2010-11-10 | 吉百利亚当斯美国有限责任公司 | 具有活性物的多区咀嚼型胶基糖 |
JP2011512818A (ja) | 2008-02-27 | 2011-04-28 | キャドバリー アダムス ユーエスエー エルエルシー | 複数領域菓子 |
ES2538224T3 (es) | 2008-05-02 | 2015-06-18 | Intercontinental Great Brands Llc | Productos de confitería a base de manitol sin azúcar multicapa y métodos para su producción |
EP2389072A1 (en) | 2009-01-22 | 2011-11-30 | Kraft Foods Global Brands LLC | Confectionery processing |
WO2011044373A2 (en) | 2009-10-08 | 2011-04-14 | Cadbury Adams Usa Llc | Co-extruded layered candy and gum apparatus and methods |
EP2316279B1 (en) | 2009-10-30 | 2013-10-09 | Intercontinental Great Brands LLC | Sugar free confectionery; methods of making same; and use in preparing multilayered confectionery. |
PL3417714T3 (pl) | 2009-12-21 | 2019-12-31 | Intercontinental Great Brands Llc | Rozdrobnione kompozycje powłokowe, powlekany wyrób cukierniczy oraz sposoby ich wytwarzania |
US20130316042A1 (en) | 2010-06-25 | 2013-11-28 | Cadbury Adams Mexico, S. De R.L. De C.V. | Enhanced release of lipophilic ingredients from chewing gum with hydrocolloids |
CN103379829B (zh) | 2011-02-14 | 2016-03-30 | 洲际大品牌有限责任公司 | 具有多重风味和质地的糖食 |
AU2012220602B2 (en) | 2011-02-23 | 2015-02-19 | Intercontinental Great Brands Llc | Flavor pre-blends for chewing gum, methods of making flavor pre-blends and chewing gum compositions thereof |
CA2829351A1 (en) | 2011-03-11 | 2012-09-20 | Intercontinental Great Brands Llc | System and method of forming multilayer confectionery |
US9480633B2 (en) | 2011-04-28 | 2016-11-01 | Kimberly-Clark Worldwide, Inc. | Temperature management composition |
WO2012149088A1 (en) | 2011-04-29 | 2012-11-01 | Kraft Foods Global Brands Llc | Encapsulated acid, method for the preparation thereof, and chewing gum comprising same |
CN103857292A (zh) | 2011-07-21 | 2014-06-11 | 洲际大品牌有限责任公司 | 用于形成和冷却咀嚼型胶基糖的系统和方法 |
JP2013195289A (ja) | 2012-03-21 | 2013-09-30 | Takasago Internatl Corp | 感覚刺激成分の評価方法 |
PL2861083T3 (pl) | 2012-06-19 | 2019-04-30 | Intercontinental Great Brands Llc | Pakowana luzem, niepowlekana guma do żucia |
RU2015106110A (ru) | 2012-08-22 | 2016-10-20 | Интэрконтинентал Грэйт Брэндс Ллс | Составы жевательной резинки и методы их изготовления |
WO2014128566A2 (en) | 2013-02-21 | 2014-08-28 | Mondelez International | Chewing gum and methods of making thereof field |
PL3009004T3 (pl) | 2013-03-29 | 2020-03-31 | Intercontinental Great Brands Llc | Przezroczyste i półprzezroczyste cukierki z płynnym nadzieniem; bezcukrowa, płynna, jadalna kompozycja |
US20160100606A1 (en) | 2013-05-31 | 2016-04-14 | Intercontinental Great Brands Llc | Chewing gum with hard, amorphous inclusions; and methods of making thereof |
WO2015051056A1 (en) | 2013-10-02 | 2015-04-09 | Intercontinental Great Brands Llc | Particulate coated chewing gum and confectionery; and methods of making the same |
ES2953728T3 (es) | 2014-02-28 | 2023-11-15 | Intercontinental Great Brands Llc | Método para recubrir núcleos comestibles y el uso de un método para limitar la adherencia de los núcleos comestibles a la pared interior del tambor |
CN106061280A (zh) | 2014-03-03 | 2016-10-26 | 洲际大品牌有限责任公司 | 制造食品的方法 |
EP3142494A1 (en) | 2014-05-15 | 2017-03-22 | Intercontinental Great Brands LLC | Multi-textured chewing gum and methods of making thereof |
JP6466879B2 (ja) * | 2016-04-04 | 2019-02-06 | トヨタ自動車株式会社 | 冷却液組成物及びこれを用いた内燃機関の運転方法 |
CN110168038B (zh) | 2017-01-10 | 2022-05-27 | 高砂香料工业株式会社 | 甲基薄荷醇衍生物以及含有其的冷感剂组合物 |
CN110312432B (zh) | 2017-02-06 | 2022-12-20 | 洲际大品牌有限责任公司 | 双重质构的糖食及其制备方法 |
CN110662429B (zh) | 2017-06-05 | 2023-10-20 | 洲际大品牌有限责任公司 | 咀嚼型胶基糖组合物及其制备方法 |
EP3668326B1 (en) | 2017-08-18 | 2023-10-04 | Intercontinental Great Brands LLC | Chewing gum compositions and methods of making thereof |
EP3699250A4 (en) | 2017-10-16 | 2021-08-25 | Takasago International Corporation | COMPOSITION PROVIDING A FRESHNESS FEELING CONTAINING A DERIVATIVE OF 2,2,6-TRIMETHYLCYLCYCLOHEXANECARBOXYLIC ACID |
PL3869971T3 (pl) | 2018-10-26 | 2024-09-09 | Intercontinental Great Brands Llc | Nadziewany wyrób cukierniczy, wyrób z polewą i sposoby jego wytwarzania |
EP4013233B1 (en) | 2019-08-14 | 2024-10-02 | Intercontinental Great Brands LLC | Confectionery chip product and methods of making the same |
WO2022076194A2 (en) | 2020-10-09 | 2022-04-14 | Intercontinental Great Brands Llc | Unwrapped hard candy product; isomalt confectionery; method of making and use thereof |
WO2023248187A1 (en) | 2022-06-24 | 2023-12-28 | Nicoventures Trading Limited | Oral composition comprising a receptor modulator |
WO2024179975A1 (en) | 2023-03-01 | 2024-09-06 | Perfetti Van Melle Benelux B.V. | Tooth whitening chewing gum; and methods of making the same |
GB202303792D0 (en) | 2023-03-15 | 2023-04-26 | Givaudan Sa | Cosmetic composition |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1082370B (de) * | 1958-01-18 | 1960-05-25 | C F Asche & Co Ag | Verfahren zur Herstellung von verformbaren Massen fuer kosmetische und pharmazeutische Zwecke |
US4136163A (en) * | 1971-02-04 | 1979-01-23 | Wilkinson Sword Limited | P-menthane carboxamides having a physiological cooling effect |
GB1351761A (en) | 1971-02-04 | 1974-05-01 | Wilkinson Sword Ltd | Substituted p-menthane carboxamides and compositions containing them |
GB1315626A (en) | 1971-02-04 | 1973-05-02 | Wilkinson Sword Ltd | Substituted p-menthanes and compositions containing them |
GB1404596A (en) | 1972-04-18 | 1975-09-03 | Wilkinson Sword Ltd | Ingestible topical and other compositions containing physiolog cal cooling agents |
US4153679A (en) * | 1972-04-18 | 1979-05-08 | Wilkinson Sword Limited | Acyclic carboxamides having a physiological cooling effect |
IT1006572B (it) * | 1972-04-18 | 1976-10-20 | Wilkinson Sword Ltd | Composizioni ingeribili locali e altre aventi un effetto fisiologi co raffreddante sulla pelle e sul le membrane mucose del corpo |
GB1421743A (en) * | 1972-04-18 | 1976-01-21 | Wilkinson Sword Ltd | Ingestible topical and other compositions |
GB1432354A (en) | 1972-07-20 | 1976-04-14 | Wilkinson Sword Ltd | Compounds having a physiological cooling effect and compo sitions containing them |
GB1434728A (en) | 1972-09-27 | 1976-05-05 | Wilkinson Sword Ltd | Compositions and articles containing phospine oxides having a physiological cooling effect and phosphine oxides for use therein |
US3936398A (en) * | 1973-03-15 | 1976-02-03 | Givaudan Corporation | Improving the odor of perfume by novel cyclic ketal |
GB1422998A (en) * | 1973-03-22 | 1976-01-28 | Wilkinson Sword Ltd | Cyclohexanecarboxamides having a physiological cooling effect and compositions containing them |
GB1471894A (en) | 1973-12-12 | 1977-04-27 | Wilkinson Sword Ltd | Compositions for application to or consumption by the body and containing a compound having a physiological cooling effect |
US4136164A (en) | 1974-04-17 | 1979-01-23 | Wilkinson Sword Limited | Certain substituted amides having a physiological cooling effect |
US4137304A (en) | 1975-04-16 | 1979-01-30 | Wilkinson Sword Limited | Cyclic substituted ureas having a physiological cooling effect |
DE2608226A1 (de) | 1976-02-28 | 1977-09-08 | Haarmann & Reimer Gmbh | Mittel mit physiologischer kuehlwirkung |
US4279891A (en) | 1979-02-08 | 1981-07-21 | American Cyanamid Company | Low alcohol content after-shave lotion |
JPS6059671B2 (ja) | 1981-02-20 | 1985-12-26 | 富士通株式会社 | 磁気バブルメモリ素子 |
US4548743A (en) * | 1984-04-20 | 1985-10-22 | International Flavors & Fragrances Inc. | Ketal and use in perfumery |
US4758599A (en) | 1986-06-04 | 1988-07-19 | American Cyanamid Company | Clear, hydroalcoholic aftershave lotion which moisturizes, conditions, and prevents irritation |
US5009893A (en) * | 1989-07-17 | 1991-04-23 | Warner-Lambert Company | Breath-freshening edible compositions of methol and a carboxamide |
DE4110973A1 (de) * | 1991-04-05 | 1992-10-08 | Haarmann & Reimer Gmbh | Mittel mit physiologischem kuehleffekt und fuer diese mittel geeignete wirksame verbindungen |
-
1993
- 1993-06-09 DE DE69313278T patent/DE69313278T2/de not_active Expired - Lifetime
- 1993-06-09 CA CA002123794A patent/CA2123794C/en not_active Expired - Lifetime
- 1993-06-09 AU AU45304/93A patent/AU4530493A/en not_active Abandoned
- 1993-06-09 AT AT93915249T patent/ATE156997T1/de not_active IP Right Cessation
- 1993-06-09 WO PCT/US1993/005455 patent/WO1993025177A1/en active Search and Examination
- 1993-06-09 EP EP93915249A patent/EP0644749B1/en not_active Expired - Lifetime
- 1993-06-09 BR BR9306575A patent/BR9306575A/pt not_active IP Right Cessation
- 1993-06-09 ES ES93915249T patent/ES2105293T3/es not_active Expired - Lifetime
- 1993-06-17 MX MX9303642A patent/MX9303642A/es unknown
-
1995
- 1995-01-18 US US08/375,193 patent/US6277385B1/en not_active Expired - Lifetime
-
1997
- 1997-10-15 GR GR970402675T patent/GR3025029T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2123794C (en) | 1998-09-15 |
ATE156997T1 (de) | 1997-09-15 |
WO1993025177A1 (en) | 1993-12-23 |
BR9306575A (pt) | 1998-12-08 |
EP0644749A1 (en) | 1995-03-29 |
EP0644749B1 (en) | 1997-08-20 |
US6277385B1 (en) | 2001-08-21 |
DE69313278D1 (de) | 1997-09-25 |
GR3025029T3 (en) | 1998-01-30 |
AU4530493A (en) | 1994-01-04 |
CA2123794A1 (en) | 1993-12-23 |
ES2105293T3 (es) | 1997-10-16 |
DE69313278T2 (de) | 1998-03-26 |
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