MX9207215A - Derivados de acidos guanidino-alquil-1,1-bis-fosfonicos, procedimientos para su preparacion y su utilizacion. - Google Patents
Derivados de acidos guanidino-alquil-1,1-bis-fosfonicos, procedimientos para su preparacion y su utilizacion.Info
- Publication number
- MX9207215A MX9207215A MX9207215A MX9207215A MX9207215A MX 9207215 A MX9207215 A MX 9207215A MX 9207215 A MX9207215 A MX 9207215A MX 9207215 A MX9207215 A MX 9207215A MX 9207215 A MX9207215 A MX 9207215A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- preparation
- hydrogen atom
- chemical structure
- guanidino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
- C07F9/405—Esters of poly(thio)phosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
- C07F9/65068—Five-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4140908 | 1991-12-12 | ||
| DE4211976 | 1992-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9207215A true MX9207215A (es) | 1993-06-01 |
Family
ID=25910001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9207215A MX9207215A (es) | 1991-12-12 | 1992-12-11 | Derivados de acidos guanidino-alquil-1,1-bis-fosfonicos, procedimientos para su preparacion y su utilizacion. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5294608A (es) |
| EP (1) | EP0546548B1 (es) |
| JP (1) | JP3377234B2 (es) |
| KR (1) | KR100269544B1 (es) |
| AT (1) | ATE152453T1 (es) |
| AU (1) | AU657018B2 (es) |
| BR (1) | BR9204984A (es) |
| CA (1) | CA2085171C (es) |
| DE (1) | DE59208426D1 (es) |
| DK (1) | DK0546548T3 (es) |
| ES (1) | ES2101012T3 (es) |
| FI (1) | FI105550B (es) |
| MX (1) | MX9207215A (es) |
| NZ (1) | NZ245414A (es) |
| RU (1) | RU2124519C1 (es) |
| TW (1) | TW222637B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030148933A1 (en) * | 1990-10-01 | 2003-08-07 | Pharma Mar S.A. | Derivatives of dehydrodidemnin B |
| GB8922026D0 (en) * | 1989-09-29 | 1989-11-15 | Pharma Mar Sa | Novel anti-viral and cytotoxic agent |
| DE4223940A1 (de) * | 1992-07-21 | 1994-01-27 | Boehringer Mannheim Gmbh | Neue acyclische Amidingruppen-haltige Diphosphonsäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| ES2129485T3 (es) * | 1992-12-02 | 1999-06-16 | Hoechst Ag | Derivados de acidos guanidinoalquil-1,1-bisfosfonicos, procedimiento para su preparacion y su utilizacion. |
| JPH06298779A (ja) * | 1993-04-15 | 1994-10-25 | Hoechst Japan Ltd | ヘテロ環イミノビスメチレンビスホスホン酸誘導体 |
| US5854227A (en) * | 1994-03-04 | 1998-12-29 | Hartmann; John F. | Therapeutic derivatives of diphosphonates |
| DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
| WO1998039344A1 (en) * | 1997-03-07 | 1998-09-11 | Metabasis Therapeutics, Inc. | Novel purine inhibitors of fructose-1,6-bisphosphatase |
| AU6691498A (en) * | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel benzimidazole inhibitors of fructose-1,6-bisphosphatase |
| IT1303672B1 (it) | 1998-07-28 | 2001-02-23 | Nicox Sa | Sali nitrati di farmaci attivi nei disordini ossei |
| AU2756701A (en) * | 2000-01-04 | 2001-07-16 | Regents Of The University Of California, The | Use of low dosage bisphosphonates to inhibit cardiac and arterial calcification |
| EP1802641B8 (en) * | 2004-10-08 | 2012-03-07 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases |
| WO2008128056A1 (en) * | 2004-10-08 | 2008-10-23 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods with enhanced potency for multiple targets including fpps, ggpps, and dpps |
| CA2646334A1 (en) * | 2006-03-17 | 2007-09-27 | The Board Of Trustees Of The University Of Illinois | Bisphosphonate compounds and methods |
| US7457149B2 (en) | 2006-05-05 | 2008-11-25 | Macronix International Co., Ltd. | Methods and apparatus for thermally assisted programming of a magnetic memory device |
| JP2010523709A (ja) * | 2007-04-12 | 2010-07-15 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | Ｆｐｐｓ、ｇｇｐｐｓ及びｄｐｐｓを含む複数の標的に対して高い効能を有するビスホスホネート化合物及び方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3225469A1 (de) * | 1982-07-05 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate |
| IL77243A (en) * | 1984-12-21 | 1996-11-14 | Procter & Gamble | Pharmaceutical compositions containing geminal diphosphonic acid compounds and certain such novel compounds |
| DE3770982D1 (de) * | 1986-04-24 | 1991-08-01 | Fujisawa Pharmaceutical Co | Diphosphonsaeure-verbindungen, verfahren zu deren herstellung und sie enthaltende arzneimittel. |
| KR880011136A (ko) * | 1987-03-11 | 1988-10-26 | 모리오까 시게오 | 아졸- 아미노메틸렌 비스포스폰산 유도체 |
| IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them |
| US4990503A (en) * | 1988-08-12 | 1991-02-05 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic bisphosphonic acid derivatives |
-
1992
- 1992-12-05 TW TW081109748A patent/TW222637B/zh active
- 1992-12-09 NZ NZ245414A patent/NZ245414A/en unknown
- 1992-12-10 US US07/988,890 patent/US5294608A/en not_active Expired - Lifetime
- 1992-12-10 FI FI925617A patent/FI105550B/fi not_active IP Right Cessation
- 1992-12-10 DK DK92121077.9T patent/DK0546548T3/da active
- 1992-12-10 AT AT92121077T patent/ATE152453T1/de not_active IP Right Cessation
- 1992-12-10 EP EP92121077A patent/EP0546548B1/de not_active Expired - Lifetime
- 1992-12-10 ES ES92121077T patent/ES2101012T3/es not_active Expired - Lifetime
- 1992-12-10 DE DE59208426T patent/DE59208426D1/de not_active Expired - Fee Related
- 1992-12-11 KR KR1019920023961A patent/KR100269544B1/ko not_active IP Right Cessation
- 1992-12-11 CA CA002085171A patent/CA2085171C/en not_active Expired - Fee Related
- 1992-12-11 JP JP33133392A patent/JP3377234B2/ja not_active Expired - Fee Related
- 1992-12-11 RU RU92004530A patent/RU2124519C1/ru not_active IP Right Cessation
- 1992-12-11 AU AU30173/92A patent/AU657018B2/en not_active Ceased
- 1992-12-11 MX MX9207215A patent/MX9207215A/es not_active IP Right Cessation
- 1992-12-11 BR BR9204984A patent/BR9204984A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE152453T1 (de) | 1997-05-15 |
| AU657018B2 (en) | 1995-02-23 |
| TW222637B (es) | 1994-04-21 |
| KR100269544B1 (ko) | 2000-10-16 |
| EP0546548B1 (de) | 1997-05-02 |
| JP3377234B2 (ja) | 2003-02-17 |
| FI925617A (fi) | 1993-06-13 |
| BR9204984A (pt) | 1993-06-15 |
| US5294608A (en) | 1994-03-15 |
| NZ245414A (en) | 1995-04-27 |
| FI925617A0 (fi) | 1992-12-10 |
| FI105550B (fi) | 2000-09-15 |
| CA2085171C (en) | 2003-12-02 |
| ES2101012T3 (es) | 1997-07-01 |
| JPH05271260A (ja) | 1993-10-19 |
| DK0546548T3 (da) | 1997-10-13 |
| DE59208426D1 (de) | 1997-06-05 |
| CA2085171A1 (en) | 1993-06-13 |
| EP0546548A1 (de) | 1993-06-16 |
| AU3017392A (en) | 1993-06-17 |
| RU2124519C1 (ru) | 1999-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |