MX9200109A - Derivados de acridina, procedimiento para su prepaderivados de acridina, procedimiento para su preparacion y composicion farmaceutica que los contieneracion y composicion farmaceutica que los contiene. . - Google Patents
Derivados de acridina, procedimiento para su prepaderivados de acridina, procedimiento para su preparacion y composicion farmaceutica que los contieneracion y composicion farmaceutica que los contiene. .Info
- Publication number
- MX9200109A MX9200109A MX9200109A MX9200109A MX9200109A MX 9200109 A MX9200109 A MX 9200109A MX 9200109 A MX9200109 A MX 9200109A MX 9200109 A MX9200109 A MX 9200109A MX 9200109 A MX9200109 A MX 9200109A
- Authority
- MX
- Mexico
- Prior art keywords
- group
- 4alkoxy
- 4alkyl
- hydrogen atom
- atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
- Laminated Bodies (AREA)
- Soft Magnetic Materials (AREA)
- Paper (AREA)
- Dry Shavers And Clippers (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919100628A GB9100628D0 (en) | 1991-01-11 | 1991-01-11 | Chemical compounds |
| GB919100637A GB9100637D0 (en) | 1991-01-11 | 1991-01-11 | Chemical compounds |
| GB919115981A GB9115981D0 (en) | 1991-07-24 | 1991-07-24 | Chemical compounds |
| GB919115956A GB9115956D0 (en) | 1991-07-24 | 1991-07-24 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9200109A true MX9200109A (es) | 1992-09-01 |
Family
ID=27450605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9200109A MX9200109A (es) | 1991-01-11 | 1992-01-10 | Derivados de acridina, procedimiento para su prepaderivados de acridina, procedimiento para su preparacion y composicion farmaceutica que los contieneracion y composicion farmaceutica que los contiene. . |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5604237A (es) |
| EP (2) | EP0569380B1 (es) |
| JP (1) | JP2783680B2 (es) |
| KR (1) | KR100220538B1 (es) |
| AT (1) | ATE153660T1 (es) |
| AU (1) | AU652996B2 (es) |
| CA (1) | CA2100258C (es) |
| CZ (1) | CZ283038B6 (es) |
| DE (1) | DE69220037T2 (es) |
| DK (1) | DK0569380T3 (es) |
| ES (1) | ES2104887T3 (es) |
| FI (1) | FI103888B1 (es) |
| GE (1) | GEP20002210B (es) |
| GR (1) | GR3024525T3 (es) |
| HU (2) | HUT68856A (es) |
| IE (1) | IE920083A1 (es) |
| IL (1) | IL100631A (es) |
| MX (1) | MX9200109A (es) |
| NO (1) | NO300267B1 (es) |
| NZ (1) | NZ241278A (es) |
| PL (1) | PL168202B1 (es) |
| RU (1) | RU2119482C1 (es) |
| SG (1) | SG45403A1 (es) |
| SK (1) | SK280864B6 (es) |
| WO (1) | WO1992012132A1 (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2104887T3 (es) * | 1991-01-11 | 1997-10-16 | Glaxo Lab Sa | Derivados de acridina. |
| TR28930A (tr) * | 1992-05-07 | 1997-07-21 | Zeneca Ltd | Alkil sübstitüentli nitrotoluen türevleri |
| GB9209872D0 (en) * | 1992-05-07 | 1992-06-24 | Ici Plc | Alkyl substituted nitrotoluene derivatives |
| EP0649410B1 (en) * | 1992-07-10 | 1997-05-02 | Laboratoires Glaxo Sa | Anilide derivatives |
| RU2036198C1 (ru) * | 1993-04-01 | 1995-05-27 | Товарищество с ограниченной ответственностью "Полисан" | N-МЕТИЛ-N-( α,D -ГЛЮКОПИРАНОЗИЛ) АММОНИЯ-2-(АКРИДОН-9-ОН-10-ИЛ)АЦЕТАТ(ЦИКЛОФЕРОН), ОБЛАДАЮЩИЙ ИНТЕРФЕРОНОГЕННОЙ, ПРОТИВОВИРУСНОЙ, В ТОМ ЧИСЛЕ АНТИВИЧ, АНТИПАРАЗИТАРНОЙ, АНТИПРОМОТОРНОЙ И РАДИОПРОТЕКТИВНОЙ АКТИВНОСТЬЮ |
| US5387685A (en) * | 1993-07-16 | 1995-02-07 | American Cyanamid Co | MDR reversal agents |
| DE4422517A1 (de) * | 1994-06-28 | 1996-01-04 | Dresden Arzneimittel | Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US6057358A (en) * | 1994-08-04 | 2000-05-02 | C&C Research Labs. | Amine derivatives, processes for producing them and a use of them as antiarrhythmic drugs |
| EP0784474A2 (en) * | 1994-10-05 | 1997-07-23 | Glaxo Wellcome Inc. | Parenteral pharmaceutical compositions containing gf120918a |
| FR2726267B1 (fr) * | 1994-10-26 | 1998-01-02 | Smithkline Beecham Lab | Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer |
| US6245805B1 (en) | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| US6395770B1 (en) | 1995-10-26 | 2002-05-28 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for administering taxanes orally to human patients |
| WO1997028166A1 (de) * | 1996-02-01 | 1997-08-07 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Thienochinoline |
| US6713517B1 (en) | 1996-03-08 | 2004-03-30 | Oxigene, Inc. | Use of aryl N-substituted carboxamides directly and as radio-and chemosensitizers for killing tumor and cancer cells and novel compounds for such use |
| RU2118532C1 (ru) * | 1996-04-10 | 1998-09-10 | Олег Викторович Травкин | Противоинфекционное, противовоспалительное и противоопухолевое лекарственное средство |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9710612D0 (en) * | 1997-05-23 | 1997-07-16 | Glaxo Group Ltd | Synthesis of acridine derivatives |
| SK157599A3 (en) * | 1997-05-27 | 2002-10-08 | Baker Norton Pharma | Method and compositions for administering taxanes orally to human patients |
| GB9718903D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| GB9812189D0 (en) * | 1998-06-05 | 1998-08-05 | Glaxo Group Ltd | Methods and compositions for increasing penetration of HIV protease inhibitors |
| WO2000000472A1 (en) * | 1998-06-30 | 2000-01-06 | Du Pont Pharmaceuticals Company | 5-ht7 receptor antagonists |
| CA2346689A1 (en) | 1998-10-08 | 2000-04-20 | Gregor James Macdonald | Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents) |
| WO2000069390A2 (en) * | 1999-05-17 | 2000-11-23 | Cancer Research Ventures Limited | Compositions for improving bioavailability of orally administered drugs |
| EP1229934B1 (en) | 1999-10-01 | 2014-03-05 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US6521635B1 (en) | 2000-01-20 | 2003-02-18 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of MXR transport by acridine derivatives |
| MXPA02008014A (es) * | 2000-02-18 | 2004-04-05 | New York Medical College | Composiciones inhibidoras de tumores de 1-nitroacridina. |
| NZ520624A (en) * | 2000-03-14 | 2004-02-27 | Actelion Pharmaceuticals Ltd | 1,2,3,4-tetrahydroisoquinoline derivatives |
| CA2408343A1 (en) | 2000-05-11 | 2002-11-07 | Banyu Pharmaceutical Co., Ltd. | N-acyltetrahydroisoquinoline derivatives |
| HUP0303719A2 (hu) * | 2000-10-16 | 2004-03-01 | Neopharm, Inc. | Mitoxantron hatóanyag-tartalmú liposzómás gyógyszerkészítmények és eljárás az előállításukra |
| CA2485430C (en) * | 2002-05-14 | 2011-12-06 | Xenova Limited | Process for the preparation of a hydrate of an anthranilic acid derivative |
| WO2004039795A2 (en) * | 2002-10-29 | 2004-05-13 | Fujisawa Pharmaceutical Co., Ltd. | Amide compounds for the treatment of hyperlipidemia |
| NZ550216A (en) | 2004-03-01 | 2009-08-28 | Actelion Pharmaceuticals Ltd | Substituted 1,2,3,4-tetrahydroisoquinoline derivatives |
| RU2346692C2 (ru) * | 2007-03-29 | 2009-02-20 | Ефаг АО | Применение 9-оксоакридин-10-уксусной кислоты, ее солей и сложных эфиров в комбинированной терапии рака яичников, способ лечения и наборы |
| SE531698C2 (sv) * | 2007-07-12 | 2009-07-07 | Respiratorius Ab | Nya bronkdilaterande a,b-omättade amider |
| WO2015142670A1 (en) * | 2014-03-15 | 2015-09-24 | Medisyn Technologies, Inc. | Anti-diabetic compounds, pharmaceutical compositions containing them, and method to treat diabetes |
| CN104434808A (zh) | 2014-07-03 | 2015-03-25 | 石药集团中奇制药技术（石家庄）有限公司 | 一种治疗性纳米粒子及其制备方法 |
| MX2020009563A (es) * | 2018-03-21 | 2020-10-05 | Izumi Tech Llc | Analogos deuterados del elacridar. |
| CN113387873B (zh) * | 2021-06-15 | 2022-09-20 | 山东第一医科大学(山东省医学科学院) | 取代二芳基类化合物其制备方法和用途 |
| CN117414367A (zh) * | 2022-08-09 | 2024-01-19 | 北京清华长庚医院 | 一种逆转仑伐替尼耐药的药物组合物及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4250182A (en) * | 1972-02-24 | 1981-02-10 | Burroughs Wellcome Co. | Pharmaceutical composition containing acridone compounds and method of using same |
| US4021551A (en) * | 1972-06-07 | 1977-05-03 | Boehringer Ingelheim Gmbh | 3,6-Bis-(heterocyclic aminoacyl-amino)-acridines and salts thereof |
| US4127573A (en) * | 1972-09-06 | 1978-11-28 | Burroughs Wellcome Co. | Ditetrazole substituted acridone compounds |
| ATE12779T1 (de) * | 1980-09-30 | 1985-05-15 | Bayer Ag | Verfahren zur herstellung eines antithrombinheparin-komplexes sowie diesen komplex enthaltende pharmazeutische mischungen. |
| NZ198115A (en) * | 1981-08-21 | 1985-05-31 | New Zealand Dev Finance | 9-anilinoacridines;pharmaceutical compositions |
| NZ201084A (en) * | 1982-06-25 | 1985-10-11 | New Zealand Dev Finance | 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such |
| IN164921B (es) * | 1986-07-22 | 1989-07-08 | Hoechst India | |
| US5104858A (en) * | 1988-09-29 | 1992-04-14 | Yale University | Sensitizing multidrug resistant cells to antitumor agents |
| CA1340821C (en) * | 1988-10-06 | 1999-11-16 | Nobuyuki Fukazawa | Heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components |
| HUT59377A (en) * | 1989-06-19 | 1992-05-28 | Wellcome Found | Process for producing drugs containing new aromatic rings |
| ES2104887T3 (es) * | 1991-01-11 | 1997-10-16 | Glaxo Lab Sa | Derivados de acridina. |
| US5296602A (en) * | 1991-03-18 | 1994-03-22 | Sloan-Kettering Institute For Cancer Research | Multisubstituted 1-hydroxy-9-acridones with anticancer activity |
| US5240936A (en) * | 1992-05-14 | 1993-08-31 | Texas A&M University System | Treating or preventing ocular inflammation or systemic imflammatory disease |
-
1992
- 1992-01-07 ES ES92901861T patent/ES2104887T3/es not_active Expired - Lifetime
- 1992-01-07 JP JP4501671A patent/JP2783680B2/ja not_active Expired - Lifetime
- 1992-01-07 GE GEAP19922653A patent/GEP20002210B/en unknown
- 1992-01-07 DE DE69220037T patent/DE69220037T2/de not_active Expired - Lifetime
- 1992-01-07 CZ CS931378A patent/CZ283038B6/cs not_active IP Right Cessation
- 1992-01-07 KR KR1019930702079A patent/KR100220538B1/ko not_active IP Right Cessation
- 1992-01-07 RU RU93051543A patent/RU2119482C1/ru active
- 1992-01-07 SK SK730-93A patent/SK280864B6/sk not_active IP Right Cessation
- 1992-01-07 WO PCT/EP1992/000020 patent/WO1992012132A1/en active IP Right Grant
- 1992-01-07 EP EP92901861A patent/EP0569380B1/en not_active Expired - Lifetime
- 1992-01-07 SG SG1996006197A patent/SG45403A1/en unknown
- 1992-01-07 CA CA002100258A patent/CA2100258C/en not_active Expired - Lifetime
- 1992-01-07 PL PL92299989A patent/PL168202B1/pl unknown
- 1992-01-07 DK DK92901861.2T patent/DK0569380T3/da active
- 1992-01-07 HU HU9301989A patent/HUT68856A/hu unknown
- 1992-01-07 AT AT92901861T patent/ATE153660T1/de not_active IP Right Cessation
- 1992-01-07 AU AU11543/92A patent/AU652996B2/en not_active Expired
- 1992-01-07 EP EP92100123A patent/EP0494623A1/en active Pending
- 1992-01-10 IE IE008392A patent/IE920083A1/en not_active IP Right Cessation
- 1992-01-10 IL IL10063192A patent/IL100631A/en not_active IP Right Cessation
- 1992-01-10 NZ NZ241278A patent/NZ241278A/en not_active IP Right Cessation
- 1992-01-10 MX MX9200109A patent/MX9200109A/es unknown
-
1993
- 1993-07-09 NO NO932512A patent/NO300267B1/no not_active IP Right Cessation
- 1993-07-09 FI FI933149A patent/FI103888B1/fi active
-
1995
- 1995-06-06 US US08/468,620 patent/US5604237A/en not_active Expired - Lifetime
- 1995-06-29 HU HU95P/P00524P patent/HU211623A9/hu unknown
-
1997
- 1997-08-22 GR GR970402168T patent/GR3024525T3/el unknown
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