MX390837B - Composiciones de proteinas estables. - Google Patents
Composiciones de proteinas estables.Info
- Publication number
- MX390837B MX390837B MX2018004695A MX2018004695A MX390837B MX 390837 B MX390837 B MX 390837B MX 2018004695 A MX2018004695 A MX 2018004695A MX 2018004695 A MX2018004695 A MX 2018004695A MX 390837 B MX390837 B MX 390837B
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic biomolecule
- reservoir
- biomolecule
- therapeutic
- porous structure
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 abstract 5
- 238000012377 drug delivery Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/08—Polyethers derived from hydroxy compounds or from their metallic derivatives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Polymers & Plastics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562242412P | 2015-10-16 | 2015-10-16 | |
| PCT/US2016/057019 WO2017066554A1 (en) | 2015-10-16 | 2016-10-14 | Stable protein compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2018004695A MX2018004695A (es) | 2019-03-14 |
| MX390837B true MX390837B (es) | 2025-03-21 |
Family
ID=57209897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018004695A MX390837B (es) | 2015-10-16 | 2016-10-14 | Composiciones de proteinas estables. |
| MX2022003376A MX2022003376A (es) | 2015-10-16 | 2018-04-16 | Composiciones de proteinas estables. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022003376A MX2022003376A (es) | 2015-10-16 | 2018-04-16 | Composiciones de proteinas estables. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20180289623A1 (enExample) |
| EP (1) | EP3362041A1 (enExample) |
| JP (3) | JP6853245B2 (enExample) |
| KR (1) | KR102731879B1 (enExample) |
| CN (2) | CN113827704B (enExample) |
| AU (2) | AU2016340072B2 (enExample) |
| CA (1) | CA3001346A1 (enExample) |
| EA (1) | EA036623B1 (enExample) |
| IL (2) | IL258570B2 (enExample) |
| MX (2) | MX390837B (enExample) |
| MY (2) | MY199546A (enExample) |
| WO (1) | WO2017066554A1 (enExample) |
| ZA (1) | ZA201802460B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2909777T3 (es) | 2011-11-18 | 2022-05-10 | Regeneron Pharma | Formulación de liberación prolongada que comprende micropartículas para su uso en el humor vítreo del ojo para tratar trastornos oculares vasculares |
| IL258570B2 (en) * | 2015-10-16 | 2024-07-01 | Regeneron Pharma | Stable protein preparations |
| US12156900B2 (en) | 2017-11-17 | 2024-12-03 | Amgen Inc. | VEGFR-Fc fusion protein formulations |
| PT4364724T (pt) | 2018-05-10 | 2025-12-16 | Regeneron Pharma | Formulações contendo uma proteína de fusão do recetor do vegf de concentração elevada |
| US20220054586A1 (en) * | 2018-09-10 | 2022-02-24 | Samsung Bioepis Co., Ltd. | Liquid composition comprising protein |
| CN112294760B (zh) * | 2019-07-26 | 2025-12-12 | 宁波新致生物科技有限公司 | 一种液体制剂及其应用 |
| WO2025235973A1 (en) * | 2024-05-09 | 2025-11-13 | Deep Brain Bci Corporation | Implantable medical devices for delivering therapeutics and brain-computer interface systems |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3756512B2 (ja) * | 1992-09-21 | 2006-03-15 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 徐放性タンパク質製剤 |
| US6004549A (en) * | 1994-12-14 | 1999-12-21 | Schering Corporation | Crystalline protein controlled release compositions |
| RU2357750C2 (ru) * | 2002-12-31 | 2009-06-10 | Элтус Фармасьютикалз Инк. | Кристаллы человеческого гормона роста и способы их получения |
| CA2530113C (en) * | 2003-06-26 | 2013-08-13 | Control Delivery Systems, Inc. | Bioerodible sustained release drug delivery systems |
| CA2588449A1 (en) * | 2004-11-24 | 2006-06-01 | Therakine Corporation | An implant for intraocular drug delivery |
| CN104434770A (zh) | 2006-06-16 | 2015-03-25 | 瑞泽恩制药公司 | 适合玻璃体内施用的vegf拮抗剂的制剂 |
| WO2008109886A1 (en) | 2007-03-08 | 2008-09-12 | The Regents Of The University Of California | Topographically engineered structures and methods for using the same in regenerative medicine applications |
| EP3000434A1 (en) | 2007-03-16 | 2016-03-30 | The Regents Of The University Of California | Nanostructure surface coated medical implants and methods of using the same |
| SG173167A1 (en) * | 2009-01-29 | 2011-08-29 | Forsight Labs Llc | Posterior segment drug delivery |
| US8623395B2 (en) * | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| CN101559041B (zh) * | 2009-05-19 | 2014-01-15 | 中国科学院过程工程研究所 | 粒径均一的多肽药物缓释微球或微囊制剂及制备方法 |
| US8417452B2 (en) | 2009-08-19 | 2013-04-09 | General Motors Llc | System for providing information to an operator of a vehicle |
| EP2600812B1 (en) * | 2010-08-05 | 2021-09-22 | ForSight Vision4, Inc. | Apparatus to treat an eye |
| HUE054113T2 (hu) | 2010-08-05 | 2021-08-30 | Forsight Vision4 Inc | Injekciós készülék gyógyszerbejuttatáshoz |
| WO2012142318A1 (en) | 2011-04-14 | 2012-10-18 | The Regents Of The University Of California | Multilayer thin film drug delivery device and methods of making and using the same |
| BR112014029760A2 (pt) | 2012-05-30 | 2017-06-27 | Univ California | dispositivos de distribuição de agente bioativo e métodos para fazer e usar os mesmos |
| US9463177B2 (en) | 2012-09-10 | 2016-10-11 | The Regents Of The University Of California | Compounds and methods for modulating vascular injury |
| EP3929218A1 (en) * | 2014-07-14 | 2021-12-29 | Amgen, Inc | Crystalline antibody formulations |
| KR101808234B1 (ko) | 2015-06-23 | 2017-12-12 | (주)알테오젠 | IgG Fc 도메인을 가지는 융합 단백질의 안정한 액상 제제 |
| IL258570B2 (en) | 2015-10-16 | 2024-07-01 | Regeneron Pharma | Stable protein preparations |
-
2016
- 2016-10-14 IL IL258570A patent/IL258570B2/en unknown
- 2016-10-14 CN CN202111110779.9A patent/CN113827704B/zh active Active
- 2016-10-14 AU AU2016340072A patent/AU2016340072B2/en active Active
- 2016-10-14 EP EP16788338.8A patent/EP3362041A1/en active Pending
- 2016-10-14 KR KR1020187013253A patent/KR102731879B1/ko active Active
- 2016-10-14 EA EA201890979A patent/EA036623B1/ru unknown
- 2016-10-14 IL IL310557A patent/IL310557A/en unknown
- 2016-10-14 MX MX2018004695A patent/MX390837B/es unknown
- 2016-10-14 JP JP2018519460A patent/JP6853245B2/ja active Active
- 2016-10-14 CA CA3001346A patent/CA3001346A1/en active Pending
- 2016-10-14 MY MYPI2022002413A patent/MY199546A/en unknown
- 2016-10-14 WO PCT/US2016/057019 patent/WO2017066554A1/en not_active Ceased
- 2016-10-14 CN CN201680067420.9A patent/CN108348462B/zh active Active
- 2016-10-14 MY MYPI2018701358A patent/MY193964A/en unknown
- 2016-10-14 US US15/766,586 patent/US20180289623A1/en active Pending
-
2018
- 2018-04-13 ZA ZA2018/02460A patent/ZA201802460B/en unknown
- 2018-04-16 MX MX2022003376A patent/MX2022003376A/es unknown
-
2021
- 2021-03-11 JP JP2021038817A patent/JP7179112B2/ja active Active
-
2022
- 2022-01-25 AU AU2022200475A patent/AU2022200475B2/en active Active
- 2022-11-15 JP JP2022182235A patent/JP7547438B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2018004695A (es) | 2019-03-14 |
| BR112018007507A2 (pt) | 2018-10-23 |
| JP2018538243A (ja) | 2018-12-27 |
| JP7179112B2 (ja) | 2022-11-28 |
| JP6853245B2 (ja) | 2021-03-31 |
| CA3001346A1 (en) | 2017-04-20 |
| AU2016340072B2 (en) | 2021-10-28 |
| MX2022003376A (es) | 2022-04-12 |
| KR102731879B1 (ko) | 2024-11-20 |
| JP7547438B2 (ja) | 2024-09-09 |
| IL258570B1 (en) | 2024-03-01 |
| AU2022200475B2 (en) | 2023-09-14 |
| JP2021098742A (ja) | 2021-07-01 |
| WO2017066554A1 (en) | 2017-04-20 |
| EA201890979A1 (ru) | 2018-10-31 |
| CN113827704A (zh) | 2021-12-24 |
| ZA201802460B (en) | 2024-09-25 |
| MY193964A (en) | 2022-11-03 |
| US20180289623A1 (en) | 2018-10-11 |
| IL258570A (en) | 2018-05-31 |
| IL310557A (en) | 2024-03-01 |
| EA036623B1 (ru) | 2020-12-01 |
| IL258570B2 (en) | 2024-07-01 |
| KR20180063311A (ko) | 2018-06-11 |
| JP2023025046A (ja) | 2023-02-21 |
| AU2016340072A1 (en) | 2018-05-10 |
| CN108348462B (zh) | 2021-10-15 |
| CN113827704B (zh) | 2024-07-12 |
| EP3362041A1 (en) | 2018-08-22 |
| MY199546A (en) | 2023-11-06 |
| AU2022200475A1 (en) | 2022-02-17 |
| CN108348462A (zh) | 2018-07-31 |
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