MX386559B - Procedimiento para la preparación de una formulación de 2-[(3-aminopropil)amino]etanotiol liofilizado. - Google Patents
Procedimiento para la preparación de una formulación de 2-[(3-aminopropil)amino]etanotiol liofilizado.Info
- Publication number
- MX386559B MX386559B MX2019006310A MX2019006310A MX386559B MX 386559 B MX386559 B MX 386559B MX 2019006310 A MX2019006310 A MX 2019006310A MX 2019006310 A MX2019006310 A MX 2019006310A MX 386559 B MX386559 B MX 386559B
- Authority
- MX
- Mexico
- Prior art keywords
- ethanethiol
- aminopropyl
- amino
- freeze
- dried
- Prior art date
Links
- YHPLKWQJMAYFCN-UHFFFAOYSA-N WR-1065 Chemical compound NCCCNCCS YHPLKWQJMAYFCN-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- JKOQGQFVAUAYPM-UHFFFAOYSA-N amifostine Chemical compound NCCCNCCSP(O)(O)=O JKOQGQFVAUAYPM-UHFFFAOYSA-N 0.000 abstract 1
- 229960001097 amifostine Drugs 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16306582.4A EP3330251A1 (en) | 2016-11-30 | 2016-11-30 | Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol |
| PCT/EP2017/080881 WO2018100008A1 (en) | 2016-11-30 | 2017-11-29 | Process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2019006310A MX2019006310A (es) | 2019-08-12 |
| MX386559B true MX386559B (es) | 2025-03-19 |
Family
ID=57542923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019006310A MX386559B (es) | 2016-11-30 | 2017-11-29 | Procedimiento para la preparación de una formulación de 2-[(3-aminopropil)amino]etanotiol liofilizado. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11021442B2 (https=) |
| EP (2) | EP3330251A1 (https=) |
| JP (1) | JP7138104B2 (https=) |
| KR (1) | KR102596798B1 (https=) |
| CN (1) | CN110300742B (https=) |
| AU (1) | AU2017369603B2 (https=) |
| CA (1) | CA3039425A1 (https=) |
| IL (1) | IL266811B (https=) |
| MX (1) | MX386559B (https=) |
| WO (1) | WO2018100008A1 (https=) |
| ZA (1) | ZA201902119B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3824880A1 (en) * | 2019-11-25 | 2021-05-26 | Clevexel Pharma | Freeze-dried powder containing 2-[(3-aminopropyl)amino]ethanethiol and its use for preparing a thermogel |
| EP4303224A4 (en) * | 2021-03-03 | 2025-02-19 | Tohoku University | PROTEIN FOLDING AGENTS |
| CN116283682B (zh) * | 2023-02-21 | 2024-08-02 | 梯尔希（南京）药物研发有限公司 | 一种同位素标记的氨磷汀代谢物的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU670567A1 (ru) * | 1978-02-06 | 1979-06-30 | Предприятие П/Я В-2343 | Способ получени дихлоргидрата бета-меркаптоэтил-1,3-пропилендиамина |
| US6239119B1 (en) | 1998-04-27 | 2001-05-29 | Medimmune Oncology, Inc. | Topical administration of amifostine and related compounds |
| US6407278B2 (en) * | 1998-11-16 | 2002-06-18 | Medimmune Oncology, Inc. | Stable amorphous amifostine compositions and methods for the preparation and use of the same |
| MXPA03004546A (es) * | 2000-11-22 | 2003-09-10 | Rxkinetix Inc | Tratamiento de mucositis. |
| WO2013163423A1 (en) * | 2012-04-25 | 2013-10-31 | Musc Foundation For Research Development | Compositions and methods for wound healing and tissue repair |
| FR2994844B1 (fr) * | 2012-08-31 | 2015-01-02 | Assist Publ Hopitaux De Paris | Formulation gelifiante a base de ketamine |
-
2016
- 2016-11-30 EP EP16306582.4A patent/EP3330251A1/en not_active Withdrawn
-
2017
- 2017-11-29 EP EP17825118.7A patent/EP3548464A1/en active Pending
- 2017-11-29 CN CN201780074153.2A patent/CN110300742B/zh active Active
- 2017-11-29 US US16/465,505 patent/US11021442B2/en active Active
- 2017-11-29 JP JP2019529868A patent/JP7138104B2/ja active Active
- 2017-11-29 KR KR1020197016544A patent/KR102596798B1/ko active Active
- 2017-11-29 AU AU2017369603A patent/AU2017369603B2/en active Active
- 2017-11-29 MX MX2019006310A patent/MX386559B/es unknown
- 2017-11-29 WO PCT/EP2017/080881 patent/WO2018100008A1/en not_active Ceased
- 2017-11-29 CA CA3039425A patent/CA3039425A1/en active Pending
-
2019
- 2019-04-04 ZA ZA2019/02119A patent/ZA201902119B/en unknown
- 2019-05-22 IL IL266811A patent/IL266811B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL266811A (en) | 2019-07-31 |
| AU2017369603B2 (en) | 2021-04-29 |
| JP7138104B2 (ja) | 2022-09-15 |
| US20200239414A1 (en) | 2020-07-30 |
| EP3330251A1 (en) | 2018-06-06 |
| KR20190085526A (ko) | 2019-07-18 |
| BR112019011006A2 (pt) | 2019-10-08 |
| KR102596798B1 (ko) | 2023-10-31 |
| BR112019011006A8 (pt) | 2023-04-11 |
| IL266811B (en) | 2021-10-31 |
| EP3548464A1 (en) | 2019-10-09 |
| CN110300742A (zh) | 2019-10-01 |
| WO2018100008A1 (en) | 2018-06-07 |
| CN110300742B (zh) | 2022-02-18 |
| CA3039425A1 (en) | 2018-06-07 |
| JP2019535801A (ja) | 2019-12-12 |
| AU2017369603A1 (en) | 2019-05-02 |
| ZA201902119B (en) | 2023-01-25 |
| MX2019006310A (es) | 2019-08-12 |
| US11021442B2 (en) | 2021-06-01 |
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