MX384438B - Compuestos farmacéuticos. - Google Patents

Compuestos farmacéuticos.

Info

Publication number
MX384438B
MX384438B MX2019004113A MX2019004113A MX384438B MX 384438 B MX384438 B MX 384438B MX 2019004113 A MX2019004113 A MX 2019004113A MX 2019004113 A MX2019004113 A MX 2019004113A MX 384438 B MX384438 B MX 384438B
Authority
MX
Mexico
Prior art keywords
pharmaceutical compounds
activity
compound
formula
cbp
Prior art date
Application number
MX2019004113A
Other languages
English (en)
Spanish (es)
Other versions
MX2019004113A (es
Inventor
David Michel Adrien Taddei
Don Smyth
Gareth Harbottle
Jonathan Shannon
Neil Anthony Pegg
Richard James Brown
Silvia Paoletta
Stuart Thomas Onions
Original Assignee
Cellcentric Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellcentric Ltd filed Critical Cellcentric Ltd
Publication of MX2019004113A publication Critical patent/MX2019004113A/es
Publication of MX384438B publication Critical patent/MX384438B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2019004113A 2016-10-18 2017-10-18 Compuestos farmacéuticos. MX384438B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1617630.7A GB201617630D0 (en) 2016-10-18 2016-10-18 Pharmaceutical compounds
PCT/GB2017/053152 WO2018073586A1 (en) 2016-10-18 2017-10-18 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
MX2019004113A MX2019004113A (es) 2019-09-09
MX384438B true MX384438B (es) 2025-03-14

Family

ID=57680668

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019004113A MX384438B (es) 2016-10-18 2017-10-18 Compuestos farmacéuticos.

Country Status (24)

Country Link
US (2) US10696666B2 (OSRAM)
EP (1) EP3529248B1 (OSRAM)
JP (1) JP7152393B2 (OSRAM)
KR (1) KR102578786B1 (OSRAM)
CN (1) CN110049983B (OSRAM)
AU (1) AU2017346453B2 (OSRAM)
CA (1) CA3039641A1 (OSRAM)
CY (1) CY1123666T1 (OSRAM)
DK (1) DK3529248T3 (OSRAM)
EA (1) EA201990643A1 (OSRAM)
ES (1) ES2828504T3 (OSRAM)
GB (1) GB201617630D0 (OSRAM)
HR (1) HRP20201444T1 (OSRAM)
HU (1) HUE052443T2 (OSRAM)
IL (1) IL266017B (OSRAM)
LT (1) LT3529248T (OSRAM)
MX (1) MX384438B (OSRAM)
PT (1) PT3529248T (OSRAM)
RS (1) RS61007B1 (OSRAM)
SG (1) SG11201903155XA (OSRAM)
SI (1) SI3529248T1 (OSRAM)
SM (1) SMT202000593T1 (OSRAM)
WO (1) WO2018073586A1 (OSRAM)
ZA (1) ZA201902334B (OSRAM)

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CN112574191B (zh) * 2019-09-29 2024-01-23 南京圣和药业股份有限公司 异噁唑杂环类化合物及其应用
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US11795168B2 (en) 2020-09-23 2023-10-24 Forma Therapeutics, Inc. Inhibiting cyclic amp-responsive element-binding protein (CREB) binding protein (CBP)
TW202227429A (zh) * 2020-11-06 2022-07-16 大陸商貝達藥業股份有限公司 P300抑制劑、包含其的藥物組合物、其應用及製備其的方法
US20240122941A1 (en) * 2020-12-25 2024-04-18 National Cancer Center Therapy based on synthetic lethality in swi/snf complex-dysfunction cancer
WO2022143773A1 (zh) * 2020-12-31 2022-07-07 南京明德新药研发有限公司 苯并咪唑类化合物及其应用
CN114989158A (zh) * 2021-03-02 2022-09-02 复旦大学 组蛋白乙酰转移酶p300溴结构域抑制剂及其药用组合物及其应用
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Also Published As

Publication number Publication date
HRP20201444T1 (hr) 2020-12-11
US20200407349A1 (en) 2020-12-31
IL266017A (en) 2019-06-30
PT3529248T (pt) 2020-09-03
CN110049983A (zh) 2019-07-23
HUE052443T2 (hu) 2021-04-28
RS61007B1 (sr) 2020-11-30
US11377443B2 (en) 2022-07-05
EA201990643A1 (ru) 2019-11-29
EP3529248A1 (en) 2019-08-28
DK3529248T3 (da) 2020-09-14
US20190375740A1 (en) 2019-12-12
BR112019007834A2 (pt) 2019-07-16
AU2017346453B2 (en) 2022-02-17
SMT202000593T1 (it) 2020-11-10
EP3529248B1 (en) 2020-08-19
CN110049983B (zh) 2022-06-14
CY1123666T1 (el) 2022-03-24
SG11201903155XA (en) 2019-05-30
GB201617630D0 (en) 2016-11-30
US10696666B2 (en) 2020-06-30
ZA201902334B (en) 2022-10-26
JP2019537571A (ja) 2019-12-26
MX2019004113A (es) 2019-09-09
NZ752354A (en) 2025-02-28
KR102578786B1 (ko) 2023-09-15
JP7152393B2 (ja) 2022-10-12
SI3529248T1 (sl) 2020-11-30
IL266017B (en) 2021-08-31
CA3039641A1 (en) 2018-04-26
WO2018073586A1 (en) 2018-04-26
LT3529248T (lt) 2020-10-26
KR20190075095A (ko) 2019-06-28
AU2017346453A1 (en) 2019-05-02
ES2828504T3 (es) 2021-05-26

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